KEGG   Osmerus eperlanus (European smelt): 134026688
Entry
134026688         CDS       T10927                                 
Symbol
plcb2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
oep  Osmerus eperlanus (European smelt)
Pathway
oep00562  Inositol phosphate metabolism
oep01100  Metabolic pathways
oep04020  Calcium signaling pathway
oep04070  Phosphatidylinositol signaling system
oep04081  Hormone signaling
oep04082  Neuroactive ligand signaling
oep04261  Adrenergic signaling in cardiomyocytes
oep04270  Vascular smooth muscle contraction
oep04310  Wnt signaling pathway
oep04371  Apelin signaling pathway
oep04540  Gap junction
oep04621  NOD-like receptor signaling pathway
oep04912  GnRH signaling pathway
oep04916  Melanogenesis
Module
oep_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:oep00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    134026688 (plcb2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    134026688 (plcb2)
   04371 Apelin signaling pathway
    134026688 (plcb2)
   04020 Calcium signaling pathway
    134026688 (plcb2)
   04070 Phosphatidylinositol signaling system
    134026688 (plcb2)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    134026688 (plcb2)
   04081 Hormone signaling
    134026688 (plcb2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    134026688 (plcb2)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    134026688 (plcb2)
  09152 Endocrine system
   04912 GnRH signaling pathway
    134026688 (plcb2)
   04916 Melanogenesis
    134026688 (plcb2)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    134026688 (plcb2)
   04270 Vascular smooth muscle contraction
    134026688 (plcb2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:oep04131]
    134026688 (plcb2)
Enzymes [BR:oep01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     134026688 (plcb2)
Membrane trafficking [BR:oep04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    134026688 (plcb2)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    134026688 (plcb2)
SSDB
Motif
Pfam: PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh PLC-beta_C EF-hand_like C2
Other DBs
NCBI-GeneID: 134026688
NCBI-ProteinID: XP_062325565
LinkDB
Position
9:17999045..18020672
AA seq 1545 aa
MDKRRYILEPPEVKDYLLKGDRFTKWSEESTKTVTVTMKMDPKGYYLYWTNQSKETEFLD
IQTIRDTRSGKYAKLPKHPKVRNVFNLDFPDSHHLAKTLTIVSGPDMVNLTYHNFFAYKE
KVTQNWADDILAIAYNPQRNNACRQVFLDKMYVRISLHTNKDGKIPVKHVYKMFPADKKR
VESSLASAHLPKGKGDTMKPDVFTEAAFKSFLMNLCPRPEIYEIFTSYSAKAKPYMTKDS
LAKFINDKQRDGRLNEELFPRTRPDQVKALIEKYEPCSSNANRGQISPEGLLFYLLGTET
SVVILDKLARCQDMNQPLPHYLIKSSHNTYLTAGQFSGVSSPEMYRQCLLAGCRCLELDC
WKGKPPEEEPIITHGFTMTTEILFKDVIEAIAESAFKTSQYPVILSFENHVDSVKQQEKM
ANYCKTIFGDALLTDPLDKYPLKPGQQIPSPAELMGKILIKNKKGSHDKPSQDSPKKTPA
PNQNTLGPAAGLCQPPPPPSTQEGQEGEGPSEETEEHEDLEEQDEEKMKNSDEGTAGQEV
TAYEEMSALVNYIQPNKFISFENAKKKNRSYSMSSFVETKGESLISKSAVEFVEYNKRQM
SRIYPKGTRMDSSNYTPQLFWNAGCQMVALNYQTMDFPMQLNMSVFEFNGRTGYLLKHDL
LRRSDKKFDPYTDRIDTIVANTLTIKIYSGQFLSDKSVKTGVEVEVIGLPGDPKKKCRTK
WSATQNAINPVWNEEPFVFEKILLPDMAHLRIVVHEENGKFLGHRIIPIEVLQSGFQHIC
LRSESNMPLSLPALFVYIEVKDYIPAAFADFTDALFNPTKNSEKLTKTQESADYVSPYEL
PLVAQTLIDKAPTAAEPEPKTAAATSPEEDVENPEDQIPSPAPEENLLEAADPNMASDSP
QDNPPAEPDGEPDPASRTEEPDVDPIPDPATEPGSTTPEPLPDASPSPDSGETIAANEPS
PQSEAPPNSIPDSTPNGKPVSEDTPTPENVPDTVTSLAFVPAAPDPTEPESSAELDTVSP
EQLIQHKSFLKLTRRQEKDLKELERKFQKKEEELLQKYADTFKNLKKKNSLKKKEGEGDV
PEPSAPGKVREQKERLQVELRALRMQKMDQTKRRKEQNATERLAKLLEMTTERHSCELRQ
LESQTKDSKKKSVTKRSGSDKTRLRRAMSCEVLEDSAQTDSGQTTDSSPQQYALVKKQTA
NLERIKDVANQKIKKSQHNHSSSPTSLHALLPACTLSYQPARSPTSLHTLLPACKLSYQP
ARSPTSLHALLPACTLSYQPAHSPTSLQALLPACTLSYQPARSPTSLHALLPACKLSYQP
AHSPTSLQALLPVCTLSYQPARSPTSLHTLLPACKLSYQPASSPTSLHALLPACKLSYQP
ALSYQPARSPTSLHALLQACKLSYQPAHSPTSLQALLPACKLSYQPASSPTSLHALLPAC
KLSHQPARSPTSLQALLPACTLSYQPASSPTCLHALLPACTLSYLPASSPTSLPALLTAC
SGLFLEEPFSEKADKGSEHSTGIPDKRGLVESTGFYRAVSNNVSV
NT seq 4638 nt   +upstreamnt  +downstreamnt
atggacaagagacgctacatcctggagccccctgaggtgaaggactacctgctgaagggg
gacaggttcaccaaatggtccgaggagtccacaaaaactgttactgtcaccatgaaaatg
gaccctaagggctattacctctactggaccaaccagagcaaggagacagagtttctagac
atccaaaccatccgagacaccagatcagggaaatatgcaaaacttcctaaacacccgaag
gtcaggaatgtgttcaacctggactttccagacagccaccatctggccaaaaccttgacc
attgtttcaggtccagatatggtcaatctgacctaccacaacttctttgcctacaaagag
aaagtgacgcagaactgggctgatgatatcctggccatagcttacaaccctcagaggaat
aacgcatgcagacaagtcttcctggacaagatgtatgttcgcatctctcttcacaccaac
aaggatggcaagatccctgtcaaacatgtttacaaaatgtttcctgccgacaagaagcga
gtggaaagttccctggcctcagcccacctgcccaaagggaagggcgacaccatgaagccg
gacgtctttaccgaggctgccttcaagtccttcctgatgaacctgtgtcctcgaccagaa
atctacgagatcttcacctcctactctgccaaggccaagccctacatgaccaaggacagc
ctagccaagttcatcaacgacaagcagcgagacggtcggctgaacgaggagctgttcccc
cggaccaggccggaccaggtcaaggccctcatagagaagtacgagccttgctcatccaac
gccaaccgaggtcagatatctcccgagggcctcctgttctacctgctgggcactgagacc
tctgtggtgatcctggacaagctggcccgctgccaggacatgaaccagcctcttcctcac
tacctcatcaagtcctctcacaacacctacctgacagccggtcagttttctggtgtgtcg
tcccctgagatgtaccgccagtgtctgctggcagggtgtcgctgtctggagctggactgt
tggaaggggaaacccccagaggaagagcccatcatcacccacggcttcaccatgaccaca
gagatcctgttcaaggatgtgatcgaagccattgctgagagcgcctttaaaacgtcccag
tatcctgtcatcctgtcctttgagaaccacgtggactcggtgaagcaacaggagaagatg
gccaactactgtaagaccatatttggtgacgctctgctgacagaccccctggacaagtac
cctctgaagccaggacagcagatccccagcccagcagagctcatggggaagattctgatc
aagaacaagaaaggaagtcatgataaacccagccaggacagcccaaagaagaccccagca
cccaaccagaacacgctgggccctgctgcgggcctctgccagcctccaccccccccctcc
acccaggagggccaagagggcgaggggccttcggaggagacggaggaacatgaggacctg
gaggagcaggatgaggaaaagatgaagaactcggatgaggggacagcgggacaggaagtg
acagcgtatgaggagatgtctgccctggtcaactacatccagcccaacaaatttatttct
tttgagaacgccaaaaagaagaacaggagctattccatgtcatcctttgtggagaccaaa
ggagagagtttgatctccaaatctgctgttgagtttgttgagtataataagcgtcagatg
agcaggatctatcctaaaggaaccaggatggactcctctaactacactccccaactgttc
tggaacgccggctgccagatggtggcgctaaactaccaaaccatggattttcccatgcag
ctgaacatgtccgtgtttgagttcaacggcagaacaggttacctcctgaaacatgacctc
cttcgacgcagcgacaagaagtttgacccctacactgacagaatagacaccattgttgcc
aacacactgaccatcaagatctattctggccagttcctgtctgacaagagtgtgaagaca
ggtgtggaggtggaggtcatagggctgccaggtgaccccaagaagaagtgccgcaccaag
tggtccgctacacaaaacgccataaacccagtgtggaacgaggaaccctttgtttttgag
aagatcttgttgcccgacatggcccacctcaggatcgtggttcatgaggagaacggcaag
tttctggggcaccggatcatccccatcgaggtcctgcagtcaggcttccagcacatctgc
ctgcgcagtgagagcaacatgccgctgtctctgccggcgctgtttgtgtacatcgaggtc
aaggactacatccctgctgctttcgcagactttacagacgccctgtttaatccaacaaag
aattcggagaagttgaccaagacacaggagtctgcagattacgtcagcccgtacgagttg
cctctcgtggcccaaacacttattgacaaagctccaactgcagcagaaccagagcccaag
actgcagctgccaccagcccagaggaggatgtggagaacccagaggaccagatcccctct
cctgcccctgaggagaacctcctggaggctgcagaccccaacatggcctcagattctccc
caggacaacccccctgcagaacctgatggagaacctgaccccgcttccagaaccgaggaa
ccggatgtggaccccatccctgatcctgccaccgaaccaggaagcaccacacctgagccc
ctccctgatgcaagcccctcccctgatagtggagagacaatcgcagccaatgaaccatcc
cctcaatctgaagctcctcccaacagcatccctgactcaaccccaaacggcaagcctgtt
tcagaggacacacccaccccagagaacgttccagacaccgtcacaagtctggctttcgtc
cctgctgcacctgaccccacggaaccagaatccagcgcagagctcgacaccgtgtcccct
gagcagctgattcagcacaagagcttcctgaagttgaccaggaggcaggagaaggatctg
aaggagctggagaggaagttccagaagaaggaggaggaactgctgcagaagtacgcagac
acctttaaaaacctgaagaagaagaactcgctgaagaagaaagagggggagggggacgtg
ccggagcccagtgccccggggaaggtgcgggagcagaaggagaggctgcaggtggagctg
cgggccctgaggatgcagaagatggaccagacaaagaggaggaaggagcagaacgccaca
gagcggctggccaagctgttggagatgaccacggagagacacagttgcgagctgagacag
ctggagagccaaaccaaggactccaagaagaaaagtgtgacgaagcgcagtggatctgac
aagacgaggctcagacgagcgatgagctgtgaggtgctggaagactctgcccagacagac
tcagggcagacaacagacagcagccctcaacaatacgctctggtgaagaaacagaccgct
aatctggagaggatcaaagatgtagctaatcagaagatcaagaagagccaacacaatcac
tcaagctctcctaccagcctgcacgctctcttaccagcctgcacgctctcctaccagcct
gcacgctctcctaccagcctgcacactctcctaccagcctgcaagctctcctaccagcct
gcacgctctcctaccagcctgcacgctctcctaccagcctgcacactctcctaccagcct
gcacactctcctaccagcctgcaagctctcctaccagcctgcacgctctcctaccagcct
gcacgctctcctaccagcctgcacgctctcctaccagcctgcaagctctcctaccagcct
gcacactctcctaccagcctgcaagctctcctaccagtctgcacgctctcctaccagcct
gcacgctctcctaccagcctgcacactctcctaccagcctgcaagctctcctaccagcct
gcaagctctcctaccagcctgcacgctctcctaccagcctgcaagctctcctaccagcct
gcactctcctaccagcctgcacgctctcctaccagcctgcacgctctcctacaagcctgc
aagctctcctaccagcctgcacactctcctaccagcctgcaagctctcctaccagcctgc
aagctctcctaccagcctgcaagctctcccaccagcctgcacgctctcctaccagcctgc
aagctctcccaccagcctgcacgctctcctaccagcctgcaagctctcctacctgcctgc
acgctctcctaccagcctgcaagctctcctacctgcctgcacgctctcctaccagcctgc
acgctctcctacctgcctgcaagctctcctaccagcctaccagctctcttaacagcctgc
tcgggtctatttctggaggagccattctctgaaaaagccgacaaaggctctgagcactcc
actggaataccagataagaggggtttggtggagagcacaggattttatcgagctgtgagc
aacaatgtctcggtttga

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