KEGG   Osmerus eperlanus (European smelt): 134030951
Entry
134030951         CDS       T10927                                 
Symbol
erbb2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2
  KO
K05083  receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
Organism
oep  Osmerus eperlanus (European smelt)
Pathway
oep04010  MAPK signaling pathway
oep04012  ErbB signaling pathway
oep04020  Calcium signaling pathway
oep04510  Focal adhesion
oep04520  Adherens junction
oep04530  Tight junction
Brite
KEGG Orthology (KO) [BR:oep00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    134030951 (erbb2)
   04012 ErbB signaling pathway
    134030951 (erbb2)
   04020 Calcium signaling pathway
    134030951 (erbb2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    134030951 (erbb2)
   04520 Adherens junction
    134030951 (erbb2)
   04530 Tight junction
    134030951 (erbb2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:oep01001]
    134030951 (erbb2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:oep04147]
    134030951 (erbb2)
   04090 CD molecules [BR:oep04090]
    134030951 (erbb2)
Enzymes [BR:oep01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     134030951 (erbb2)
Protein kinases [BR:oep01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   134030951 (erbb2)
Exosome [BR:oep04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   134030951 (erbb2)
CD molecules [BR:oep04090]
 Proteins
  134030951 (erbb2)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like TM_ErbB1 ABC1 Tcell_CD4_C Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 134030951
NCBI-ProteinID: XP_062330367
LinkDB
Position
12:complement(17731657..17752917)
AA seq 1269 aa
MEAARSFLYLRVLLLGVSGALSREVCLGTDMKLALPSSEQNHYQILKLLYSGCQVVHGNL
EITHLHGQPDLSFLQGIVEVQGYVLVAHVSVGMIPLDSLRIIRGSQLFNNSYALAVVDNT
AAGAGLRTLRLRSLTEMLLGGVYIWGNPQLCFPDPRNMMWRDTLDNQNTHAAELRLQAQA
PGCPKCSCKNRGCWGETPQDCQTWTSIECASGCLRCKGDHSNDCCHNQCAAGCTGPKDSD
CLACRHFNNSGVCKDSCPPPNTYDKVTFQSKPNPDKKFSFGASCVKTCPHNYLAMEEACT
MVCPKANQEVITMQPDGQEVQNCEKCEGECPKVCYGLGMGGLQGVTMVTSAIIDQFSGCD
KIFGSLAFLKQSFTDDPVTNTSGLTLRQLDVFNKLEEITGYLYIDEWPANWTDLSVFENL
RVIRGRMLYKGVFSLGIQHLQIRSLGLRSLRSVSGGLVLLNDNPQLCYTTSLPLGQLLHP
TQGPHSIVSGNQDPQLCEEQGRVCDPLCSGGCWGPGPRQCVSCSASQRGADCVEECHLYQ
GSVREYQDGSLCGVCHSECRPINGSASCHGPGPHQCAECLHLQDGGVCVSRCPSGVKEEQ
GTVWKYSNASGHCLSCNTNCTLSCTEMDERGCPVHSQTGPGTSIAAAVGGVILFLILLAL
LVFYLRRQKKLRRKETMRRILQEHELVEPLTPSGAVPNQAQMRILKETELKKLRVLGSGA
FGTVYKGVWAPDGESVKIPVAIKVLRENTSPKANKEILDEAYVMAGVASPYVCRLLGICL
TSTVQLVTQLMPYGCLLDYVRENQERIGSQCLLNWCVQIAKGMSYLEDVRLVHRDLAARN
VLVKNQNHVKITDFGLARLLDVDETEYHADGGKVPIKWMALESILHRKFTHQSDVWSYGV
TVWELMTFGAKPYDQIPARDIPELLEGGDRLPQPLVCTIDVYMIMVKCWMIEPDSRPRFR
VLVSEFSAMARDPSRYVVIQNDEQMSLSSPVESQFFRMLLEEEGPHMRDLLDAEEYLVPQ
PNFFRAQGDAPSRHPSHRSADQSLEGEGPLATGPKGMYSSLETLGRSQYPTLPLGGSSGP
WTPPYPSLARSPSAGGHSDSVFLDGSCEDVPERYCKDPTFPGGEEGGVETDGPAHRLQHH
NHTLPRGSQRAGHHGNAAPEYVNQQVQPPRPALPDRPSTLPRRPQDRRRPSGLKNPEYGL
APGHSGEHPEYLVPLPTSPAFDNRYYLDLPATAWAGGAGGAARHINGFVTPTAENPEYLG
LADTWGGHT
NT seq 3810 nt   +upstreamnt  +downstreamnt
atggaggcggcgagaagttttctgtatctccgggtactgctactcggagtgtcgggcgcg
ttgagcagagaagtgtgtctggggactgacatgaagctggccctgccctccagtgagcag
aaccactaccagatcctgaagctgctctactctggctgccaggtcgtccacggcaacctg
gagatcacacacctgcacggccagccagacctatcctttttgcagggcatcgtggaggtg
caggggtatgtgctggtggctcatgtgtcagtgggcatgatccccttggacagccttcgc
atcatcaggggcagccagctgttcaataactcctacgccctcgccgtggtggacaacaca
gccgcaggggcggggcttaggaccctgcgcctccgcagcctgacagagatgctgctggga
ggggtgtatatttgggggaacccccagctgtgtttccctgatccccggaacatgatgtgg
agagacacactggacaaccagaacacacatgctgcagagctcagactgcaggctcaggct
cctggctgtcccaagtgttcctgcaagaaccgaggatgctggggagagaccccccaggac
tgtcagacctggaccagtatcgagtgtgcgtcagggtgtctgaggtgtaagggagatcat
tccaatgactgctgccataaccagtgtgctgcaggatgcaccgggcccaaggactcagac
tgtctggcgtgccgtcacttcaacaacagcggggtgtgtaaggacagctgcccccccccc
aacacctacgacaaggtcaccttccagtctaaacccaacccagacaagaagttcagcttc
ggagcctcctgcgtgaagacatgtcctcataactatctagccatggaggaagcctgcacc
atggtttgtcccaaagccaaccaggaagtgatcactatgcagccggatggacaggaagtg
cagaattgtgaaaagtgtgaaggggagtgtcccaaagtgtgctatgggctgggcatgggg
gggcttcagggcgttaccatggtgacctctgccatcatagaccagttttccggatgtgac
aagatcttcggcagtctggccttcctgaagcagagcttcactgatgaccccgtgaccaac
acgtcaggcctgactctcagacagctagacgtgttcaacaaactggaggaaatcacaggt
tacctgtacatcgatgagtggcctgccaactggacagacctgagtgtgtttgaaaacctg
agagtaatcaggggaagaatgctctataagggggtgttctccctgggcatacagcacctt
cagatccgctccctgggcctgcgctcgctgcgtagcgtgagtggaggtctggtgctgctc
aacgacaacccccagctctgctacaccacctccctgcccttggggcagctgctgcacccc
acacagggcccccacagcatcgtcagcggcaaccaggacccccagctctgtgaggagcag
ggccgtgtgtgtgaccccctgtgttcgggggggtgctggggccccgggccccgacagtgc
gtctcctgctcggcctcccagcgaggagcggactgtgtggaggagtgtcacctctaccaa
ggctctgtgcgggagtaccaggacggctctctctgcggcgtctgtcactcagaatgtcga
ccaatcaatggctccgcttcctgccatggcccggggccccaccagtgtgcggagtgtctg
cacctgcaagacgggggagtgtgtgtgtcgcgctgccccagcggggtgaaggaggagcag
ggcaccgtctggaagtacagcaacgccagcgggcactgtctgtcctgcaacaccaactgc
acgctctcgtgcacggagatggacgagagaggctgtccagttcactcccagacaggacca
gggacgtccatcgcggcggcggtgggcggagtcattctgttcctgatcctattggctctg
ctggtgttctacctgcgcaggcagaagaagctgcgcaggaaggagactatgaggaggatc
ctgcaggagcacgagctggtggagcctctaactcccagcggtgcagtgcccaaccaggcc
cagatgaggatcctgaaggagaccgagctgaagaagctgagagtgctcgggtccggagcc
ttcggcaccgtctacaagggggtgtgggctcctgatggggagagtgtaaagatcccggtg
gccatcaaggttttgcgtgagaacacttctcctaaagccaacaaggagatcctggatgag
gcgtatgtgatggcgggcgtggccagcccgtacgtgtgtcgtctgctggggatctgcttg
acctccacggtgcagctggtcacccagctgatgccctacggctgcctgctggactacgtc
agggagaaccaggagcgcatcggctcccagtgcctcctcaactggtgcgtccagatcgcc
aaggggatgagctacttagaggacgtccgtctggtgcatcgtgacctggcagcgcggaac
gtcctggtgaagaaccagaaccacgtgaagatcacagacttcggtctggcccgcctgctg
gacgtagacgagaccgagtaccacgccgacgggggcaaagtccccatcaagtggatggca
ctggagtccatcctccacaggaagttcacccaccagagtgacgtgtggagctacggggtg
acggtgtgggagctgatgacgttcggggcgaagccgtatgaccagatcccggcgcgggac
atccccgagcttctggagggaggagaccgcctgccacagccgctcgtctgcaccatcgac
gtctacatgatcatggtcaagtgctggatgattgagccagacagcagaccgaggttcagg
gttctggtgtcagagttcagcgccatggcccgtgacccctcccgctacgtggtcatccag
aacgacgagcagatgagcctgtcgtccccggtggagagccagttcttccggatgcttctg
gaggaggagggtcctcacatgagggatctcctggacgctgaggagtacctggtgccgcag
cccaacttcttcagagcgcagggagacgcgccctccagacacccctctcacaggagcgca
gaccagagcctggaaggagaggggcccctggccactggccctaagggcatgtactcctcc
ctggagaccctggggcgcagccagtaccccaccctgcccctggggggcagcagcggcccc
tggacgcccccgtacccttcgctggcccggagcccgtcagcgggggggcactcagactca
gtgtttctggacgggagctgtgaggatgtcccggagcgctactgtaaggaccccacgttc
cccggcggcgaggaggggggcgtggagacggatggccctgcccaccgcctgcagcatcac
aaccacacgctgccccgcgggagccagcgagctggtcaccatggcaacgccgcgccagag
tacgtaaaccagcaggtgcagccccctcggccggccctcccggaccgccccagcaccctg
ccccgcaggccccaggacaggaggaggcccagcggcctgaagaacccagagtacggcctg
gcccccggacacagtggggagcacccagagtacctggtccctctccccacctccccggcc
ttcgacaaccgctactacctggacctgccagccacggcctgggctgggggggcggggggg
gcagccagacacatcaacgggtttgtgacgcccacggctgaaaacccggagtacctgggc
ctggcggacacctgggggggccacacctga

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