Otolemur garnettii (small-eared galago): 100940365
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Entry
100940365 CDS
T07855
Symbol
NDUFS1
Name
(RefSeq) NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
KO
K03934
NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:
7.1.1.2
]
Organism
oga
Otolemur garnettii (small-eared galago)
Pathway
oga00190
Oxidative phosphorylation
oga01100
Metabolic pathways
oga04714
Thermogenesis
oga04723
Retrograde endocannabinoid signaling
oga04932
Non-alcoholic fatty liver disease
oga05010
Alzheimer disease
oga05012
Parkinson disease
oga05014
Amyotrophic lateral sclerosis
oga05016
Huntington disease
oga05020
Prion disease
oga05022
Pathways of neurodegeneration - multiple diseases
oga05208
Chemical carcinogenesis - reactive oxygen species
oga05415
Diabetic cardiomyopathy
Module
oga_M00143
NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
Brite
KEGG Orthology (KO) [BR:
oga00001
]
09100 Metabolism
09102 Energy metabolism
00190 Oxidative phosphorylation
100940365 (NDUFS1)
09150 Organismal Systems
09156 Nervous system
04723 Retrograde endocannabinoid signaling
100940365 (NDUFS1)
09159 Environmental adaptation
04714 Thermogenesis
100940365 (NDUFS1)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
100940365 (NDUFS1)
09164 Neurodegenerative disease
05010 Alzheimer disease
100940365 (NDUFS1)
05012 Parkinson disease
100940365 (NDUFS1)
05014 Amyotrophic lateral sclerosis
100940365 (NDUFS1)
05016 Huntington disease
100940365 (NDUFS1)
05020 Prion disease
100940365 (NDUFS1)
05022 Pathways of neurodegeneration - multiple diseases
100940365 (NDUFS1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
100940365 (NDUFS1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
100940365 (NDUFS1)
Enzymes [BR:
oga01000
]
7. Translocases
7.1 Catalysing the translocation of protons
7.1.1 Linked to oxidoreductase reactions
7.1.1.2 NADH:ubiquinone reductase (H+-translocating)
100940365 (NDUFS1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Molybdopterin
Fer4_Nqo3
Fer4_NDSU1
Fer2_4
NADH-G_4Fe-4S_3
NADH_dhqG_C
Fer2
Motif
Other DBs
NCBI-GeneID:
100940365
NCBI-ProteinID:
XP_003785053
Ensembl:
ENSOGAG00000011226
UniProt:
H0X4D4
LinkDB
All DBs
Position
Unknown
AA seq
727 aa
AA seq
DB search
MLRIPVRRALMGLSKSPKGCVRTTATAASNLIEVFVDGQSVMVEPGTTVLQACEKVGMQI
PRFCYHERLSVAGNCRMCLVEIEKAPKVVAACAMPVMKGWNILTNSEKSKKAREGVMEFL
LANHPLDCPICDQGGECDLQDQSMMFGNDRSRFLEGKRAVEDKNIGPLVKTIMTRCIQCT
RCIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNIIDICPVGALTSKPYAFTA
RPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINEEWISDKTRFAYDGLKRQ
RLTEPMVRNEKGLLTYTSWEDALSRVAGMLQSFQGKDVAAIAGGLVDAEALVALKDLLNR
VDSDTLCTEEVFPTAGAGTDLRSNYLLNTTIAGVEEADVVLLVGTNPRFEAPLFNARIRK
SWLHNDLKVALIGSPVDLTYTYDHLGDSPRILQDIASGSHSFSQVLKEAKKPMVVLGSSA
LQRSDGAAILAAVSNIAQKIRMTSGVTSDWKVMNILHRVANQVAALDLGYKAGVEAIRKN
PPKVLFLLGADGGCITRQDLPKDCFIIYQGHHGDVGAPIADVIFPGAAYTEKSATYVNME
GRAQQTKVAVTPPGLAREDWKIIRALSEIAGITLPYDTLDQVRNRLEEVSPNLVRYDDVE
GANYFQQANELSKLVNQQLLADPLVPPQLTIKDFYMTDAISRASQTMAKCVKAVTEGAQA
VEEPSIC
NT seq
2184 nt
NT seq
+upstream
nt +downstream
nt
atgctaaggatacctgtaagaagggccttaatgggcctttctaagtctcccaaaggatgt
gttcgaacaactgccacagcagcaagcaacttgattgaagtatttgttgatggtcagtct
gtcatggtggaaccaggaacaactgtcctccaagcttgtgagaaggttggcatgcagatc
ccccgattctgttatcatgaaagattatctgttgctggaaattgcagaatgtgccttgtt
gaaattgagaaagctcctaaggttgtagctgcttgtgccatgccagtaatgaaaggttgg
aatatcctgacaaattcagaaaaatccaagaaagcaagagaaggcgtgatggagttctta
ttagcaaaccacccactggactgccctatttgtgaccaaggaggtgaatgtgatctgcaa
gaccagtccatgatgtttggaaatgataggagccgatttttagaagggaagcgtgctgtg
gaggacaagaacattgggccattggtaaagaccatcatgactagatgtatacagtgtact
cgctgcattaggttcgcaagtgaaattgcaggagtagatgatttgggaacaacgggcaga
ggaaatgatatgcaagttggtacatacattgaaaagatgttcatgtctgaactgtctggg
aatatcattgatatctgccctgtaggtgccctaacctctaaaccttatgcctttactgct
cggccttgggaaacaagaaagacagaatcaattgatgtcatggatgcagttggaagtaat
attgtggttagcacaagaactggagaagtaatgaggattttgccacgtatgcatgaggac
attaatgaagagtggatctctgataaaaccagatttgcttatgatgggctaaaacgtcaa
agacttacggagccgatggtcagaaacgaaaagggtcttttaacctatacctcctgggag
gatgcactctctcgtgtagctggaatgttgcagagttttcaaggcaaagatgtggcagca
attgcaggtggcttggtggatgctgaagccctagtagctctcaaagatttgctcaataga
gtggactctgacaccttatgcactgaagaagtcttccccaccgcaggagctggcacagat
ttgcgttccaattatcttcttaatactacaattgctggagtggaagaggcagatgttgtc
cttctggttggtacaaatccacgttttgaggcaccactatttaatgctagaattcgaaag
agttggcttcataatgatctaaaagtggcccttataggtagtccagtggacctcacttac
acatatgaccacctgggagactccccccgaattcttcaagacattgcttctggtagccat
tcatttagccaggtcctaaaggaagctaaaaaaccaatggtggttttaggcagttctgca
ctccaaagaagtgatggagcggcaattcttgcagctgtttccaacatcgcacaaaagatt
cggatgactagtggtgttactagtgattggaaagttatgaacatccttcatagggttgcg
aatcaagtagctgctttggaccttggctataaagcaggggtggaagcaattcgcaagaac
ccgcctaaagtactgtttctcctaggagcagatggaggttgtatcacacgacaggatttg
ccaaaggattgttttattatttatcaaggacatcatggtgacgttggagctcccatagct
gatgtcatcttcccaggagctgcttacacagagaaatctgctacttatgtcaatatggag
ggcagagctcagcagactaaagtagcagtgacacctcctggcttggcaagagaagattgg
aaaattataagagccctttctgagattgcaggtataactcttccatatgatactctggat
caagtgaggaacagattggaggaagtctctcctaatcttgttcgatatgatgatgttgaa
ggggctaactactttcagcaggcaaatgaactgtccaagctagtgaaccagcaacttctt
gctgacccacttgttccacctcagctaaccataaaagacttctacatgacagatgccatt
agcagagcctcccagacaatggccaagtgtgtcaaagctgtcacagagggtgcccaggca
gtagaagagccatccatttgctga
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