KEGG   Otolemur garnettii (small-eared galago): 100941865
Entry
100941865         CDS       T07855                                 
Symbol
SRC
Name
(RefSeq) proto-oncogene tyrosine-protein kinase Src
  KO
K05704  tyrosine-protein kinase Src [EC:2.7.10.2]
Organism
oga  Otolemur garnettii (small-eared galago)
Pathway
oga01521  EGFR tyrosine kinase inhibitor resistance
oga01522  Endocrine resistance
oga04012  ErbB signaling pathway
oga04015  Rap1 signaling pathway
oga04062  Chemokine signaling pathway
oga04081  Hormone signaling
oga04137  Mitophagy - animal
oga04144  Endocytosis
oga04360  Axon guidance
oga04370  VEGF signaling pathway
oga04510  Focal adhesion
oga04520  Adherens junction
oga04530  Tight junction
oga04540  Gap junction
oga04611  Platelet activation
oga04613  Neutrophil extracellular trap formation
oga04625  C-type lectin receptor signaling pathway
oga04727  GABAergic synapse
oga04750  Inflammatory mediator regulation of TRP channels
oga04810  Regulation of actin cytoskeleton
oga04912  GnRH signaling pathway
oga04915  Estrogen signaling pathway
oga04917  Prolactin signaling pathway
oga04919  Thyroid hormone signaling pathway
oga04921  Oxytocin signaling pathway
oga04926  Relaxin signaling pathway
oga05100  Bacterial invasion of epithelial cells
oga05135  Yersinia infection
oga05152  Tuberculosis
oga05161  Hepatitis B
oga05163  Human cytomegalovirus infection
oga05167  Kaposi sarcoma-associated herpesvirus infection
oga05168  Herpes simplex virus 1 infection
oga05203  Viral carcinogenesis
oga05205  Proteoglycans in cancer
oga05207  Chemical carcinogenesis - receptor activation
oga05208  Chemical carcinogenesis - reactive oxygen species
oga05219  Bladder cancer
oga05417  Lipid and atherosclerosis
oga05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:oga00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    100941865 (SRC)
   04015 Rap1 signaling pathway
    100941865 (SRC)
   04370 VEGF signaling pathway
    100941865 (SRC)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    100941865 (SRC)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    100941865 (SRC)
   04137 Mitophagy - animal
    100941865 (SRC)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100941865 (SRC)
   04520 Adherens junction
    100941865 (SRC)
   04530 Tight junction
    100941865 (SRC)
   04540 Gap junction
    100941865 (SRC)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100941865 (SRC)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100941865 (SRC)
   04613 Neutrophil extracellular trap formation
    100941865 (SRC)
   04625 C-type lectin receptor signaling pathway
    100941865 (SRC)
   04062 Chemokine signaling pathway
    100941865 (SRC)
  09152 Endocrine system
   04912 GnRH signaling pathway
    100941865 (SRC)
   04915 Estrogen signaling pathway
    100941865 (SRC)
   04917 Prolactin signaling pathway
    100941865 (SRC)
   04921 Oxytocin signaling pathway
    100941865 (SRC)
   04926 Relaxin signaling pathway
    100941865 (SRC)
   04919 Thyroid hormone signaling pathway
    100941865 (SRC)
  09156 Nervous system
   04727 GABAergic synapse
    100941865 (SRC)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100941865 (SRC)
  09158 Development and regeneration
   04360 Axon guidance
    100941865 (SRC)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    100941865 (SRC)
   05207 Chemical carcinogenesis - receptor activation
    100941865 (SRC)
   05208 Chemical carcinogenesis - reactive oxygen species
    100941865 (SRC)
   05203 Viral carcinogenesis
    100941865 (SRC)
  09162 Cancer: specific types
   05219 Bladder cancer
    100941865 (SRC)
  09172 Infectious disease: viral
   05161 Hepatitis B
    100941865 (SRC)
   05168 Herpes simplex virus 1 infection
    100941865 (SRC)
   05163 Human cytomegalovirus infection
    100941865 (SRC)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100941865 (SRC)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    100941865 (SRC)
   05152 Tuberculosis
    100941865 (SRC)
   05100 Bacterial invasion of epithelial cells
    100941865 (SRC)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100941865 (SRC)
   05418 Fluid shear stress and atherosclerosis
    100941865 (SRC)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100941865 (SRC)
   01522 Endocrine resistance
    100941865 (SRC)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:oga01001]
    100941865 (SRC)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:oga04131]
    100941865 (SRC)
Enzymes [BR:oga01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     100941865 (SRC)
Protein kinases [BR:oga01001]
 Non-receptor tyrosine kinases
  SRC family
   100941865 (SRC)
Membrane trafficking [BR:oga04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    100941865 (SRC)
 Endocytosis
  Clathrin-mediated endocytosis
   Kinases
    100941865 (SRC)
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    100941865 (SRC)
  Macropinocytosis
   Kinases
    100941865 (SRC)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_9 SH3_2 SH2_1 SH3_10 DUF7063 ABC1 Haspin_kinase SH3_3
Other DBs
NCBI-GeneID: 100941865
NCBI-ProteinID: XP_012659430
Ensembl: ENSOGAG00000015510
LinkDB
Position
Unknown
AA seq 536 aa
MGSNKSKPKDASQRRRSLEPSENAHAVGGGAFPTSQTPSKPASADGHRGPSAAFASAAAE
PKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGD
WWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNTENPRGTFLVRES
ETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGL
CHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTL
KPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKY
LRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYT
ARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVER
GYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL
NT seq 1611 nt   +upstreamnt  +downstreamnt
atgggcagcaacaagagcaagcccaaggatgccagccagcggcgccgcagcctggagccc
tccgagaacgcccatgctgtaggagggggcgccttccccacctcccagacccccagcaag
ccagcttcggccgacggccaccgcggacccagcgcagccttcgcctccgccgccgcagag
cccaagctgttcggaggtttcaactcctcggacacggtcacctccccgcagagggcgggg
ccactggctggcggagtgaccacctttgtggctctctatgattatgagtcacggacggag
actgacctgtccttcaagaaaggggaacggctccagattgtcaacaacacagagggagac
tggtggctggcccactcgctcagcaccggacagacaggctacatccccagcaactatgtg
gcgccctctgactccatccaggccgaggagtggtactttggcaagatcaccagacgagag
tccgagaggttactgctcaacaccgagaacccgagagggaccttcttagtacgagaaagt
gagaccacaaaaggtgcctactgcctctctgtgtccgacttcgacaacgccaagggcctc
aacgtgaagcactacaagatccgcaagctggacagtggtggcttctacatcacctcccgc
acccagttcaacagcctgcagcagctggtggcctactactccaaacacgccgacggcctg
tgccatcgcctcaccaccgtgtgccccacgtccaagccgcagactcagggcctggccaag
gatgcctgggagatccctcgggagtcactgcggcttgaggtcaagctgggccagggctgc
tttggagaggtgtggatggggacctggaatggcactactagggtggccatcaaaacccta
aagccgggcacgatgtctccagaggccttcctgcaggaggcccaggtcatgaagaaactg
aggcacgagaagctggtgcagctgtatgcagtggtgtctgaggagcccatctacattgtt
acggagtacatgagcaaggggagtttgctggactttctcaagggggagacaggcaagtac
ctgcgactgcctcagctggtggacatggctgctcagatcgcttcagggatggcatatgtg
gagcggatgaactatgtccaccgggacctccgtgctgccaacatcctggtgggcgagaac
ctggtatgcaaggtggctgactttgggctggcccggctcattgaagacaacgagtacaca
gcccggcaaggtgccaaatttcccatcaagtggacggctccagaagctgcgctctatggc
cgattcaccatcaagtcggatgtgtggtcctttgggatcctgctgacagagctcacaaca
aagggacgggtcccctaccctgggatggtgaatcgtgaggtgctggaccaggttgagcga
ggctaccggatgccctgcccacccgagtgtcctgagtccctgcatgacctcatgtgccag
tgctggcggaaggagccagaggagcggcctaccttcgagtacctgcaggcctttctggag
gactacttcacgtccactgagccccagtaccagcccggagagaacctctag

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