KEGG   Otolemur garnettii (small-eared galago): 100941909
Entry
100941909         CDS       T07855                                 
Symbol
PPP1CA
Name
(RefSeq) serine/threonine-protein phosphatase PP1-alpha catalytic subunit
  KO
K06269  serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
Organism
oga  Otolemur garnettii (small-eared galago)
Pathway
oga03015  mRNA surveillance pathway
oga04022  cGMP-PKG signaling pathway
oga04024  cAMP signaling pathway
oga04114  Oocyte meiosis
oga04218  Cellular senescence
oga04261  Adrenergic signaling in cardiomyocytes
oga04270  Vascular smooth muscle contraction
oga04390  Hippo signaling pathway
oga04510  Focal adhesion
oga04611  Platelet activation
oga04720  Long-term potentiation
oga04728  Dopaminergic synapse
oga04750  Inflammatory mediator regulation of TRP channels
oga04810  Regulation of actin cytoskeleton
oga04910  Insulin signaling pathway
oga04921  Oxytocin signaling pathway
oga04931  Insulin resistance
oga05031  Amphetamine addiction
oga05034  Alcoholism
oga05168  Herpes simplex virus 1 infection
oga05205  Proteoglycans in cancer
oga05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:oga00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    100941909 (PPP1CA)
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    100941909 (PPP1CA)
   04024 cAMP signaling pathway
    100941909 (PPP1CA)
   04022 cGMP-PKG signaling pathway
    100941909 (PPP1CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    100941909 (PPP1CA)
   04218 Cellular senescence
    100941909 (PPP1CA)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100941909 (PPP1CA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100941909 (PPP1CA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100941909 (PPP1CA)
  09152 Endocrine system
   04910 Insulin signaling pathway
    100941909 (PPP1CA)
   04921 Oxytocin signaling pathway
    100941909 (PPP1CA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100941909 (PPP1CA)
   04270 Vascular smooth muscle contraction
    100941909 (PPP1CA)
  09156 Nervous system
   04728 Dopaminergic synapse
    100941909 (PPP1CA)
   04720 Long-term potentiation
    100941909 (PPP1CA)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100941909 (PPP1CA)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    100941909 (PPP1CA)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    100941909 (PPP1CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    100941909 (PPP1CA)
   05034 Alcoholism
    100941909 (PPP1CA)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    100941909 (PPP1CA)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    100941909 (PPP1CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:oga01009]
    100941909 (PPP1CA)
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:oga03021]
    100941909 (PPP1CA)
   03019 Messenger RNA biogenesis [BR:oga03019]
    100941909 (PPP1CA)
   03041 Spliceosome [BR:oga03041]
    100941909 (PPP1CA)
Enzymes [BR:oga01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     100941909 (PPP1CA)
Protein phosphatases and associated proteins [BR:oga01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    Catalytic subunits
     100941909 (PPP1CA)
Transcription machinery [BR:oga03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     100941909 (PPP1CA)
Messenger RNA biogenesis [BR:oga03019]
 Eukaryotic type
  mRNA processing factors
   3' end processing
    Cleavage and polyadenylation specificity factor (CPSF) complex
     100941909 (PPP1CA)
Spliceosome [BR:oga03041]
 Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    100941909 (PPP1CA)
SSDB
Motif
Pfam: Metallophos STPPase_N
Other DBs
NCBI-GeneID: 100941909
NCBI-ProteinID: XP_003798371
Ensembl: ENSOGAG00000033516
UniProt: H0XUE6
LinkDB
Position
Unknown
AA seq 330 aa
MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLK
ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD
KNKGKYGQFSGLNPGGRPITPPRNSAKAKK
NT seq 993 nt   +upstreamnt  +downstreamnt
atgtccgacagcgagaagctcaacctggactctatcatcgggcgcctgctggaagtgcag
ggctcacgacctggaaagaatgtacagctgacagaaaatgagatacgtggtctgtgcctc
aaatcccgggagattttcctgagccagcccattcttttggaactggaggcacccctcaag
atatgtggtgacatccatggccagtactacgacctcctgcggctgtttgagtatgggggc
ttccctccggagagcaactacctctttctgggggactatgtggaccggggcaagcaatcc
ttggagacaatctgcctgctgctggcctataagatcaagtaccctgagaatttcttcctg
ctccgtgggaaccatgagtgtgccagcatcaaccggatctatggtttctacgatgagtgt
aagagacgctacaacatcaaactgtggaaaaccttcactgactgctttaactgcctgccc
attgcagccattgtagacgagaagatcttctgctgccatggaggcctgtccccagacctg
cagtctatggagcagattcggcgcatcatgcggcccacagatgtgcctgaccagggcctg
ctgtgtgacctgctgtggtcagaccctgacaaggatgtgcagggatggggtgagaatgac
cgtggtgtctcctttacctttggagctgaggtggtggctaagttcctgcacaaacacgac
ttggaccttatctgccgagcacaccaggtggtagaagatggctatgagttctttgccaag
cggcagctggtgacacttttctcagctcccaactactgtggcgagtttgacaatgctggt
gccatgatgagtgtagatgagaccctcatgtgctccttccaaatcctcaagcccgctgac
aagaacaaggggaaatatgggcagttcagtggcctgaaccctggaggacgacccatcacc
ccaccccgcaattctgccaaagccaagaaatag

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