Otolemur garnettii (small-eared galago): 100942489
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Entry
100942489 CDS
T07855
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1 isoform X1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
oga
Otolemur garnettii (small-eared galago)
Pathway
oga04140
Autophagy - animal
oga04141
Protein processing in endoplasmic reticulum
oga04210
Apoptosis
oga04932
Non-alcoholic fatty liver disease
oga05010
Alzheimer disease
oga05012
Parkinson disease
oga05014
Amyotrophic lateral sclerosis
oga05016
Huntington disease
oga05017
Spinocerebellar ataxia
oga05022
Pathways of neurodegeneration - multiple diseases
oga05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
oga00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
100942489 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100942489 (ERN1)
09143 Cell growth and death
04210 Apoptosis
100942489 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
100942489 (ERN1)
05012 Parkinson disease
100942489 (ERN1)
05014 Amyotrophic lateral sclerosis
100942489 (ERN1)
05016 Huntington disease
100942489 (ERN1)
05017 Spinocerebellar ataxia
100942489 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
100942489 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100942489 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
100942489 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oga01001
]
100942489 (ERN1)
Enzymes [BR:
oga01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
100942489 (ERN1)
Protein kinases [BR:
oga01001
]
Serine/threonine kinases: Other
IRE family
100942489 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
100942489
NCBI-ProteinID:
XP_023366784
Ensembl:
ENSOGAG00000003863
LinkDB
All DBs
Position
Unknown
AA seq
972 aa
AA seq
DB search
MRAQREVIILMERFLLQIFGSTSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDPV
LQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMGKK
QDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYFD
YAASLPDDDMDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRKVM
HINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMVH
EGVAVVPRGSTLPLLDGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKSKLNYLRNYWLL
IGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVISLVDQTTENAPTTVSSG
VEEKSARAPAKPEAPVDSMLKDMATIILSTFLLIGWVAFIITYPMSMHQQQQLQHQQFQK
ELEKIQLLQQQQLPFHGSGDAAQDSELLDISGPYSESSGTSSPSTSPRASNHSLCSGSSA
SKTSPYLEQDDEDEETSMVMVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILPEC
FSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDFAHLGLEP
ITLLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAVGRHSF
SRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQANI
LLGAYSLDCFHPEKHEDVIAHELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFFQDV
SDRIEKEPLDGPVVKQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLRAMR
NKKHHYRELPTEVQETLGSLPDDFVRYFTSRFPHLLLHTYRAMELCGHERLLQPYYSHEP
PEPQPPVTPDTH
NT seq
2919 nt
NT seq
+upstream
nt +downstream
nt
atgcgtgcccaacgtgaagtaatcatattgatggaaagattcttgttgcagatttttgga
agtaccagcacagtgacgcttcctgagaccctgttgtttgtgtcaaccttggatggaagt
ttgcatgctgtcagcaaaaggacgggctcaatcaaatggactttaaaagaagatccggtc
ctgcaggtcccaacacacgtggaagagcctgccttcctcccagatcccaatgacggcagc
ctatacacacttgggggcaagaataatgaaggtttgacaaaacttccatttaccatccca
gagctggtgcaggcatccccatgccgaagttcagatggaattctctacatgggtaaaaag
caagacatctggtatgttattgaccttctcactggggagaagcagcagactttgtcatcc
gcctttgcagacagtctgtgcccatcaacctctcttctgtatcttgggcgaacagaatat
accatcaccatgtacgacaccaaaacccgggagctccggtggaacgccacctactttgac
tacgcagcctcgctgcctgatgacgacatggactataagatgtcccactttgtgtccaat
ggcgatgggctggtggttactgtggacagtgaatccggggacgtcctgtggatccaaaac
tatgcctcccctgtggtggctttctacgtctggcagcgggagggtctgcggaaggtgatg
cacatcaacgtcgccgtggaaaccttgcgctacctgaccttcatgtcgggggaggtgggg
cgcatcaccaagtggaagtaccccttccccaaggagacggaggccaagagtaagctgacg
cccaccctgtacgttgggaagtactcgaccagcctctatgcctccccctccatggtgcac
gagggggttgctgttgtgccccgaggcagcactctccctttgctggacggcccccagact
gatggcgtcaccattggagacaaaggggagtgtgtgatcacgcctagcacagacctcaag
tttgaccctggactcaaaggcaagagcaagctcaactacttgcggaattactggcttctg
ataggacaccatgagaccccgctgtctgcatctaccaagatgctggagagatttcccaac
aatctgcccaagcatcgagaaaatgtgattcctgcagattcagagaaaaagagctttgag
gaagttatcagcctggtggaccagactacagaaaatgcgccgaccactgtgtcttcgggt
gtggaggagaagtctgcccgtgcccctgccaagcccgaggcccccgtggactccatgctg
aaggacatggccaccatcatcctgagcaccttcctgctcatcggctgggtggccttcatc
atcacctaccccatgagcatgcaccagcagcagcagctccagcaccagcagttccagaag
gagctggaaaagatccagctcctgcagcagcagcagctgcccttccacggctccggggat
gctgcccaggacagtgagctcctggacatatctggcccgtactcggagagctcgggcacc
agcagccccagcacatcccccagagcctccaaccactcgctctgctccggcagctccgcc
tccaagaccagcccctacctggagcaggatgacgaggatgaggaaaccagcatggtgatg
gttgggaaaatttcattctgtcctaaagacgtcttgggccacggagctgagggcacaatt
gtgtaccggggcatgtttgacaaccgagatgtggcagtgaagaggatcctccccgagtgc
ttcagcttcgcagaccgcgaggtccagctgctacgggaatcagacgagcacccgaacgtg
atccgctacttctgcacagagaaggaccggcagttccagtacattgccatcgagctatgc
gcggccaccctgcaggagtacgtggagcagaaggactttgcccacctcggcctggagccc
atcacactgctgcagcagaccacctcggggctggcccacctccactccctcaacatcgtt
cacagagacctgaagccccacaacattctcctgtccatgcccaacgcacatggcaggatc
aaggccatgatctccgactttggcctctgtaagaagctagcagtgggcaggcacagcttc
agccgccgttctggggtgcctggcacagagggctggattgccccagagatgctgagtgag
gactgcaaggagaaccctacctacacggtggacatcttctctgcaggctgcgtcttttac
tatgtgatctctgagggcagccaccctttcggcaagtccctgcagcggcaagccaacatc
ctcctgggtgcctacagcctcgactgcttccaccctgagaagcacgaagacgtcattgca
catgaactaatcgagaaaatgattgcgatggatccccagaaacgcccctcagccaagcac
gtgctcaaacacccgttcttctggagcctggagaagcagctccagttctttcaggacgtt
agtgaccggatagaaaaggaacccctggacggcccggtggtgaagcagctggagcgaggc
gggagagccgtggtgaagatggactggcgggagaacatcaccgtccccctccagacagat
ctgcgtaaattcagaacctataagggtggctccgtaagggacctcctccgtgccatgaga
aataagaagcaccactaccgggagcttcccacggaggtacaggagacgctgggctccctc
ccggacgacttcgtgcgctacttcacgtcacgcttcccccacctgctcttgcacacctac
cgggccatggagctgtgcggccacgagaggctcctccagccctactactcccacgagccc
ccagagccccagccccccgtgactccagacacccactga
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integrated database retrieval system
