Otolemur garnettii (small-eared galago): 100943444
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Entry
100943444 CDS
T07855
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
oga
Otolemur garnettii (small-eared galago)
Pathway
oga00310
Lysine degradation
oga01100
Metabolic pathways
oga05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
oga00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
100943444 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
100943444 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
oga03036
]
100943444 (DOT1L)
Enzymes [BR:
oga01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
100943444 (DOT1L)
Chromosome and associated proteins [BR:
oga03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
100943444 (DOT1L)
HMT complexes
Dot1-containing complex
100943444 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DOT1
Motif
Other DBs
NCBI-GeneID:
100943444
NCBI-ProteinID:
XP_023368271
Ensembl:
ENSOGAG00000003711
LinkDB
All DBs
Position
Unknown
AA seq
1535 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNTTTPTKVT
ENKAPGPPDAPVDSGAEEDKAGTTATKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMNTA
NPDRKPKKNQTALDLLHAQTVSQTASSSPQDAYRSPHSPFYQLPPSVQRPSPNPLLGAPT
PPALQKLLESFKIQYLQFLAYTKTPQYKANLQQLLDQEKEKNAQLLGTAQQLLSHCQAQK
EEIRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEKDNNQLRNQSLQLL
KARCEELKLDWATLSLETLLKEKQALRSQISEKQRHCLELQISIVELEKSQRQQELLQLK
SCVPPDDALSTHLRGKGTLSRDLEADPSRLHLELDCAKFSLPHFSSMSPELSMNGHATSY
ELCGALSRPSSKQNTPQYLASPLDQEVVPCTPSHGGRLRAEKLSGLAVPDYTRLSPAKIV
LRRHLSQDHAASSKAATSELHPRAEHIKENGLPYQSPGTSNSMKLSPQDPRPPSPGALQL
TGEKNSEKGLKERAYGSSGEAITSLPVSIPLSTVQPSKLPVSIPLASVVLPSRAERVRST
PSPVPQPRDSSSTLEKQIGANAHGAGSKSLALAPTGFSYAGSVAISGALVGSPAPLTSGA
ELATFEESSSSGSLFATVGSRSSTPQHPPLLAQSRSSRPASPTHQLSSSPRLGGATQGLL
PDTSKGDLPSDTGFLDPESEAKRRIVFTISTGISCTKQSPSSKHSPLNMGARGDCGQSHG
QDSRKRGRRKRASAGTPSLSAGVSPKRRALPPVAGLFTQPSGSPLNLNSMVSNINQPLEI
TAISSPENSLKSSPIPYQDHDQPPVLKKERPLGQTNGAHYSPLTSDEEQGSEDEPSSARI
ERKIATISLESKSPPKTLENGGSLAGRKLAPASEPVNSSKWKSTFSPISDIGLAKPADSP
LQANSALSQSSLFVLRPTLEEPGASDAKLTAHPRKGFPGSLPGADGLNSSPNPSHGFAFS
GGLATELNLHSFSDGASLSHKGPEALGSPLSFPSQRGKEASEANPFLSRRQLDSLKGEGC
KGKEAGEGGPALCGPAEKVPPPLSNKATKSRDRELDLKNGHNLFISAAAVPPGGRLSGPS
LAPAVSSAGSVAPPTQTHRPFLGTFTPGPQFTLGPVSLQANLSSVAGSSVLQSLFSSVPA
AAGLVHVSSAATRLTNSHAMGSFSSGVTGGTVGGN
NT seq
4608 nt
NT seq
+upstream
nt +downstream
nt
atgggggagaagctggagctgaggctcaagtcgcccgtaggggccgagcccgccgtctac
ccgtggccgctgccggtttacgacaaacatcacgatgctgctcatgaaatcatcgagacc
atccgatgggtttgtgaagaaatcccggatcttaagcttgctatggagaattatgttttg
atagactatgacaccaaaagcttcgaaagcatgcagaggctctgtgacaagtacaaccgg
gccatcgacagcattcaccagctgtggaagggcaccacccagcctatgaagctgaacact
cgtccatccaacgggcttctgcggcacatcctacagcaggtctacaaccactcggtgacc
gaccccgagaagctcaacaattatgagcccttctcacctgaggtatatggggagacctcc
ttcgacctggtggctcagatgattgacgagatcaagatgactgaggatgatctgtttgtg
gacttggggagtggtgtaggccaggttgtgctccaggtcgccgcagccaccaactgcaaa
catcactatggtgtcgagaaagcggatatcccagccaagtacgcagagaccatggaccga
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacattggagaga
ggcgatttcctctccgaagagtggagagagcggattgccaacacgagtgttatatttgtg
aataactttgcctttggtcctgaggtggatcaccagctgaaggagcgattcgcaaacatg
aaggaaggtggcaggattgtgtcctcaaaaccctttgcacctttgaacttcagaataaac
agtagaaacttgagtgacattggcacgatcatgcgtgttgtggagctgtcacccctgaag
ggctcggtgtcgtggacggggaagccggtctcctactacctgcacactatcgaccggacc
atacttgaaaattatttttctagtctgaaaaacccaaaactcagggaggaacaagaggca
gctcgacgccggcagcagcgagaaaataaaagcaacacaaccacccccaccaaggtgaca
gagaacaaggcacccggccccccagatgcccctgtggattctggtgctgaggaagataaa
gccggaaccactgccaccaaaaagccatctccctctaaagcccgtaagaagaagctgaac
aagaaagggaggaagatggctggccgcaaacgtggacgtcccaagaaaatgaacactgca
aaccccgaccgaaagcccaagaagaaccaaactgcactggatctcctacacgctcaaact
gtgtctcagacagcgtcctcctcaccccaggatgcctacaggtcacctcacagcccgttc
tatcagctacctccgagtgtgcaacggccctcccctaacccactgctgggggcgcccacc
ccacctgcgctgcagaagctgctagagtccttcaagattcagtacctgcaattcctggca
tacacaaaaaccccccagtacaaggccaatctgcagcagctgctggaccaggagaaggag
aagaatgcgcagctgctaggcacggctcagcagctactcagccactgccaggcacagaag
gaggagatcaggaggctattccagcagaagctcgatgagctgggtgtgaaggctctgacc
tacaacgacctgatccaagcccagaaggagatctctgcacacaaccagcagcttcgggag
cagtcagaacagctggagaaggacaacaaccagctgcgcaaccagagcctgcagctgctc
aaggctcggtgtgaagagctgaagctggactgggccacactgtccctggaaacgctactg
aaggagaagcaggctctgcggagccagatctcagagaagcagcggcattgcctggagctg
cagatcagcattgtggagctggagaagagccagcggcagcaggagctcctgcaactcaag
tcctgcgtgcctcctgatgacgccctgtctacacacctgcgtgggaaaggcaccctgagc
cgagatctggaggctgaccccagccggctccaccttgagctagactgtgccaaattctca
ctgccccacttcagcagcatgagcccagaactctccatgaatggccatgcaaccagctat
gagctctgtggtgccctgagccgaccctcgtccaagcagaacaccccccagtacctggcc
tcccccttggaccaggaggtggtgccctgtaccccaagccatggtggccggctgcgggcg
gagaagctgtctggcctagctgtgcctgactataccaggctctccccagccaagattgtg
ctgcgccggcacctgagccaggaccatgcagcatcaagcaaggcagccaccagtgagctt
cacccacgagctgaacacatcaaggagaatggtcttccctaccagagccctggcacatcc
aacagcatgaagctaagccctcaggacccacggcctccttcccctggagccttacagctc
accggggagaagaacagcgagaagggtctaaaggagcgagcgtatggcagcagtggggag
gctatcactagcctgcccgtcagcatcccgctgagcacagtacagcccagcaagcttcct
gtcagcatccctctggccagtgtggtgctgcccagccgtgcagaaagagtgaggagtacc
ccgagtcctgtgccacagccccgagactcctcatccacacttgaaaagcagattggtgct
aatgcccacggtgctggcagcaagagccttgccctggctcccacaggtttctcctatgct
ggctcggtggccatcagtggggccttagttggcagccctgcaccactcacgtctggagct
gagctggccacttttgaggagtcctccagttcagggagcctcttcgccactgtggggtcc
cggagctcgacgccacaacacccacccttgctggcccagtcccgcagctcccgcccagcc
tctcctacccaccagctgtcctccagcccccggctgggtggggccacccagggtctcctt
cctgacaccagcaagggagacctgccctctgacaccggctttttagatccggagagtgag
gccaaacggagaatcgtcttcaccatctccactggcatcagctgcaccaaacagtcacct
tccagcaagcatagccctctgaatatgggcgcccgtggggactgtgggcagagccatgga
caggacagccgcaagcggggccgtcgaaagagagcatctgctgggacccccagcctgagt
gcaggcgtgtctccaaagcgtcgggccttgccacctgtggctggcctctttacgcagccg
tcggggtcccccctcaacctaaactccatggtcagtaacatcaatcagcccttggagatt
acggccatctcttcccctgagaactcattgaagagctcccccatcccctaccaggaccat
gaccagccacccgtgctcaaaaaggagcggcccctgggccagaccaatggggcacactat
tccccactgacctcagacgaggagcagggctcggaggatgagcctagcagtgcccgcatt
gagagaaaaattgcaacaatctccttagaaagcaaatctcccccgaagaccttagagaat
ggtggcagcttggcaggaaggaagctggcgcccgcgagcgagcctgtcaacagcagcaag
tggaagtctaccttctcgcccatctccgacattggcctggccaagcctgcagacagcccg
ctgcaggccaactctgccctgagtcagagctccctgtttgtgcttcggcccacccttgag
gagcctggtgcctccgatgccaagctaaccgctcacccccggaaaggctttcctggctcc
ttgccaggggctgatgggctcaactcgagccccaacccttcccatggctttgccttcagc
gggggcctggccacggaactcaacctccatagcttcagtgatggtgcttctctctctcac
aagggccctgaggccctgggctcccccctgagcttcccctcgcagcggggcaaagaggcc
tcggaggccaaccctttcctcagcaggaggcagctggacagcctgaagggtgagggctgc
aagggcaaggaggccggtgagggcggcccagccctgtgtgggcctgccgagaaggtgccc
ccaccactgagcaacaaggccaccaagagccgtgaccgtgagcttgacctcaagaatggc
cacaacctcttcatctctgcagcagctgtgcctcctgggggccgcctcagtggccccagc
ctggccccagcagtatcctctgcaggcagcgtggccccccctactcagactcaccggccc
tttttgggcaccttcaccccgggcccgcagttcacattggggcctgtgtccctgcaggcc
aacctcagctcagtggcaggctcatctgtgctacagtccttgtttagctccgtgccggct
gctgcaggcctggtacacgtgtcctctgccgccaccagattgacgaactcacacgccatg
ggcagcttctcctccggggtgacaggcggaacagttggaggtaactag
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integrated database retrieval system
