Otolemur garnettii (small-eared galago): 100944394
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Entry
100944394 CDS
T07855
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor isoform X1
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
oga
Otolemur garnettii (small-eared galago)
Pathway
oga01521
EGFR tyrosine kinase inhibitor resistance
oga01522
Endocrine resistance
oga04010
MAPK signaling pathway
oga04014
Ras signaling pathway
oga04015
Rap1 signaling pathway
oga04066
HIF-1 signaling pathway
oga04068
FoxO signaling pathway
oga04081
Hormone signaling
oga04114
Oocyte meiosis
oga04140
Autophagy - animal
oga04144
Endocytosis
oga04150
mTOR signaling pathway
oga04151
PI3K-Akt signaling pathway
oga04152
AMPK signaling pathway
oga04211
Longevity regulating pathway
oga04213
Longevity regulating pathway - multiple species
oga04510
Focal adhesion
oga04520
Adherens junction
oga04550
Signaling pathways regulating pluripotency of stem cells
oga04730
Long-term depression
oga04913
Ovarian steroidogenesis
oga04914
Progesterone-mediated oocyte maturation
oga05200
Pathways in cancer
oga05202
Transcriptional misregulation in cancer
oga05205
Proteoglycans in cancer
oga05214
Glioma
oga05215
Prostate cancer
oga05218
Melanoma
oga05224
Breast cancer
oga05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
oga00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100944394 (IGF1R)
04014 Ras signaling pathway
100944394 (IGF1R)
04015 Rap1 signaling pathway
100944394 (IGF1R)
04066 HIF-1 signaling pathway
100944394 (IGF1R)
04068 FoxO signaling pathway
100944394 (IGF1R)
04151 PI3K-Akt signaling pathway
100944394 (IGF1R)
04152 AMPK signaling pathway
100944394 (IGF1R)
04150 mTOR signaling pathway
100944394 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
100944394 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
100944394 (IGF1R)
04140 Autophagy - animal
100944394 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
100944394 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
100944394 (IGF1R)
04520 Adherens junction
100944394 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
100944394 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
100944394 (IGF1R)
04914 Progesterone-mediated oocyte maturation
100944394 (IGF1R)
09156 Nervous system
04730 Long-term depression
100944394 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
100944394 (IGF1R)
04213 Longevity regulating pathway - multiple species
100944394 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100944394 (IGF1R)
05202 Transcriptional misregulation in cancer
100944394 (IGF1R)
05205 Proteoglycans in cancer
100944394 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
100944394 (IGF1R)
05214 Glioma
100944394 (IGF1R)
05218 Melanoma
100944394 (IGF1R)
05215 Prostate cancer
100944394 (IGF1R)
05224 Breast cancer
100944394 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100944394 (IGF1R)
01522 Endocrine resistance
100944394 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oga01001
]
100944394 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
oga04090
]
100944394 (IGF1R)
Enzymes [BR:
oga01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
100944394 (IGF1R)
Protein kinases [BR:
oga01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
100944394 (IGF1R)
CD molecules [BR:
oga04090
]
Proteins
100944394 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Furin-like
Pkinase
fn3
Ig_DSCAM-DSCAML_C
Kinase-like
Motif
Other DBs
NCBI-GeneID:
100944394
NCBI-ProteinID:
XP_003788691
Ensembl:
ENSOGAG00000012193
LinkDB
All DBs
Position
Unknown
AA seq
1367 aa
AA seq
DB search
MKSGSGGGSPTSLWGLLFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPLCEKTTINNEYNYRCWTTNHCQKMCPSACGKRACTENNECCHPECLGSCS
TPDNATACVACRHYYYAGVCVPACPPGTYRFEGWRCVDRDFCANIPSAESSDSEGFVIHD
GECMQECPSGFIRNGTQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYSF
YVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDVLHFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRH
NYCSKDKIPIRKYADGTIDIEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRK
VFENFLHNSIFVPRPERKRRDVMQVANTTMSSRSRNTTAVDTYNITDPEELETEYPFFES
RVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTW
EPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGN
YTARIQATSLSGNGSWTDPVFFYVQAKTGYENFIHLIIALPVAVLLVVGGLFLMLYVFHR
KRNNNRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMNRELGQGSFGMVYEGVAKG
VVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIME
LMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARN
CMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGV
VLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFL
EIIRSVKDEMEPGFQEVSFYYSEENKPPEPEELDLEPENMESVPLDPSASSSSLPLPDRH
SGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC
NT seq
4104 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctccggaggagggtccccgacctcgctgtgggggctcctgtttctctcc
gccgcgctctcgctctggccaacgagtggagaaatctgcgggccgggcattgatatccgc
aacgactatcagcagctgaagcgcctggagaactgcacagtgatcgagggctacctgcac
atcctcctcatctccaaggcggaggattaccgcagctaccgcttccccaagctcacggtc
atcactgaatacttgctgctgttccgagtggctggcctcgagagcctcggagacctcttt
cctaacctcacggtcatccgtggctggaaactcttctataattacgccctggtcatcttc
gagatgaccaatctcaaggatattgggctttacaacctgaggaacattactcggggggcc
atcaggattgagaaaaatgcagacctctgttacctctccactgtggactggtccttgatc
ctggatgcggtgtccaataactacattgtggggaacaagcccccgaaggagtgtggggac
ctgtgtccggggaccatggaggagaagcctttgtgcgagaagaccaccatcaataacgag
tacaactaccgctgctggaccacaaatcactgccagaaaatgtgcccgagcgcgtgcggg
aagcgggcgtgcacggagaacaacgagtgttgccaccccgagtgcctgggcagctgcagc
acgcccgacaacgccaccgcctgcgtggcctgccgccactactactacgccggcgtctgc
gtgcccgcctgcccacctggcacctacaggttcgagggctggcgctgcgtggaccgggac
ttctgcgccaatatccccagtgcagagagcagcgactctgaggggttcgtgatccacgat
ggcgagtgcatgcaggagtgcccctcgggcttcatccgcaatggcacgcagagcatgtac
tgcattccttgtgaaggtccttgccccaaggtctgtgaggaagaaaagaaaacaaaaact
attgattctgttacttctgctcagatgctccaaggatgtaccatcttcaagggcaatctg
ctcattaatatccgacgaggcaataacatcgcttcagaactggagaacttcatggggctc
attgaagtagtgacaggctatgtgaagatccgccattcccacgccttggtctccttgtcc
ttcctgaaaaacctccgcctcatcttaggagaggaacagctagaagggaattactccttc
tacgtcctggacaaccagaacttgcagcagctatgggactgggaccaccgtaacctgact
atcaaagcagggaaaatgtactttgccttcaatcccaaattgtgtgtttctgaaatttat
cgcatggaggaagtgacaggaactaaaggacgccagagcaaaggggacataaacaccagg
aacaatggggagagagcctcctgtgaaagtgatgtcctgcatttcacctccaccaccacg
tggaagaatcgcatcatcataacctggcaccgataccggccccctgactacagggatctc
atcagcttcaccgtttactacaaggaagcaccctttaaaaatgtcacagaatatgatggg
caggatgcctgtggctccaacagctggaacatggtggacgtggacctcccacccaacaaa
gatgttgagcctggcatcttacttcatgggctgaagccctggacccagtacgctgtttac
gtcaaggctgtgaccctcaccatggtggagaatgaccacatccgtggggccaagagtgaa
atcttgtacattcgcaccaatgcttcagttccatccattcccctggacgtgctttcagca
tcaaactcctcttctcagctgatcgtgaagtggaaccctccttctctgcccaatggcaac
ctgagctactatatcgtgcggtggcagcggcagcctcaggacagctacctttaccggcat
aattactgctccaaagacaaaattcccatcaggaagtacgctgatggcaccattgacatc
gaagaggtgacagagaatcccaagactgaagtgtgtggtggagagaaagggccttgctgt
gcttgtcccaaaaccgaagccgagaagcaggccgagaaggaggaggctgagtaccgcaaa
gtcttcgagaatttcctgcacaactccatctttgtgcccagacctgaaaggaagcgaagg
gacgtcatgcaagtggccaacactaccatgtccagccgaagcaggaacaccacagcagtg
gacacctacaatatcacagacccggaggagcttgagacagagtaccctttttttgagagc
agagtagacaacaaagagagaactgtcatttcaaacctgcggccttttacattgtaccgc
attgatatccatagctgtaaccacgaggctgagaagctgggctgcagtgcctccaacttt
gtgtttgcaagaaccatgcctgcagaaggagcagatgacattcctgggccagtcacctgg
gagccaaggcctgaaaactccatctttttaaagtggccagaacctgagaatcccaatgga
ttgattctaatgtatgaaattaaatatggatcacaagttgaggatcaacgggaatgtgta
tccagacaggagtacaggaaatacggaggggctaagctgaaccggctaaacccagggaac
tatacagcccgaattcaggctacctctctctctgggaatggatcatggacagaccctgtg
ttcttctatgtccaggccaaaacaggatatgaaaatttcatccatctgatcattgctctg
cccgtggctgtcctgctggtcgtgggagggttgttcctcatgctgtacgtcttccacaga
aagagaaataacaacaggcttgggaatggagtgctgtatgcgtctgtgaacccagagtac
ttcagcgctgctgatgtgtatgtacctgacgagtgggaggtagctcgagagaaaatcacc
atgaacagagagctcgggcaggggtcatttgggatggtctacgaaggagttgccaagggc
gtggttaaagatgagcctgaaaccagggtggccataaaaacggtgaacgaggccgcaagc
atgcgtgaaaggattgagtttctcaacgaggcttctgtgatgaaggagttcaattgtcac
catgtggtgcggttgctcggtgtggtgtcccaaggtcagccaacgctggtcatcatggag
ctgatgacacggggtgatctcaaaagttacctcaggtctctgaggccagaaatggagaat
aatccagtcttagcacctccaagtctaagcaagatgatccagatggctggagagattgca
gatggcatggcatacctcaatgccaataagtttgtccacagagaccttgctgcccggaac
tgtatggtggctgaagatttcactgtcaaaattggagactttggtatgactcgagacatc
tatgagacagactactaccggaaaggagggaaaggcttgctgcctgtgcgctggatgtcc
cccgagtccctcaaggacggtgtcttcaccactcactcggatgtctggtcctttggggtc
gtcctctgggagatcgccacgctggctgagcagccctaccagggcttgtccaacgagcaa
gtcttgcgcttcgtcatggagggcggccttctggacaagccggacaactgccccgacatg
ctgttcgagctcatgcgcatgtgctggcagtacaaccccaagatgcgcccatccttcctg
gagatcatccgcagtgtcaaggacgagatggagcccggcttccaggaggtctccttctac
tacagtgaggagaacaagccacctgaaccagaggagttggacctggagccggagaacatg
gagagcgtccccctggacccttcggcctcctcttcctccctgccactgcctgacagacac
tcaggacacaaggccgaaaatggcccgggccctggagtgctggtcctgcgagccagcttc
gatgagaggcagccttatgcgcacatgaatgggggccgtaagaatgagcgggcgctgcca
ctgccccagtcctccacctgctga
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integrated database retrieval system
