KEGG   Otolemur garnettii (small-eared galago): 100945898
Entry
100945898         CDS       T07855                                 
Symbol
MAP2K4
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 4 isoform X4
  KO
K04430  mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
Organism
oga  Otolemur garnettii (small-eared galago)
Pathway
oga04010  MAPK signaling pathway
oga04012  ErbB signaling pathway
oga04620  Toll-like receptor signaling pathway
oga04664  Fc epsilon RI signaling pathway
oga04668  TNF signaling pathway
oga04912  GnRH signaling pathway
oga04926  Relaxin signaling pathway
oga04935  Growth hormone synthesis, secretion and action
oga04936  Alcoholic liver disease
oga05132  Salmonella infection
oga05135  Yersinia infection
oga05142  Chagas disease
oga05161  Hepatitis B
oga05166  Human T-cell leukemia virus 1 infection
oga05167  Kaposi sarcoma-associated herpesvirus infection
oga05169  Epstein-Barr virus infection
oga05208  Chemical carcinogenesis - reactive oxygen species
oga05417  Lipid and atherosclerosis
oga05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:oga00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100945898 (MAP2K4)
   04012 ErbB signaling pathway
    100945898 (MAP2K4)
   04668 TNF signaling pathway
    100945898 (MAP2K4)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100945898 (MAP2K4)
   04664 Fc epsilon RI signaling pathway
    100945898 (MAP2K4)
  09152 Endocrine system
   04912 GnRH signaling pathway
    100945898 (MAP2K4)
   04926 Relaxin signaling pathway
    100945898 (MAP2K4)
   04935 Growth hormone synthesis, secretion and action
    100945898 (MAP2K4)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    100945898 (MAP2K4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100945898 (MAP2K4)
   05161 Hepatitis B
    100945898 (MAP2K4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100945898 (MAP2K4)
   05169 Epstein-Barr virus infection
    100945898 (MAP2K4)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100945898 (MAP2K4)
   05135 Yersinia infection
    100945898 (MAP2K4)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    100945898 (MAP2K4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100945898 (MAP2K4)
   05418 Fluid shear stress and atherosclerosis
    100945898 (MAP2K4)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    100945898 (MAP2K4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:oga01001]
    100945898 (MAP2K4)
Enzymes [BR:oga01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     100945898 (MAP2K4)
Protein kinases [BR:oga01001]
 Serine/threonine kinases: STE group
  STE7 family
   100945898 (MAP2K4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Seadorna_VP7 Pkinase_fungal Haspin_kinase Choline_kinase APH
Other DBs
NCBI-GeneID: 100945898
NCBI-ProteinID: XP_003791131
Ensembl: ENSOGAG00000016618
LinkDB
Position
Unknown
AA seq 410 aa
MAAPSPSGGGGSGGGSGSGTPGPVGSPAPGHPAVSSMQGFQINFCEKAQSKRKALKLNFA
NPPFKSTARFTLNPNPTGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIG
RGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALF
REGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRD
IKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSD
VWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLT
KDESKRPKYKELLKHPFILMYEERTVEVACYVCKILDQMPATPSSPMYVD
NT seq 1233 nt   +upstreamnt  +downstreamnt
atggcggctccgagcccgagcggcggcggcggctccgggggtggcagcggcagcggtacc
ccgggccccgtagggtccccggcgccgggccacccggccgtcagcagcatgcagggcttt
cagataaacttctgtgaaaaggcacaaagtaaacgcaaagcactgaagttgaattttgca
aatccacctttcaaatctacagcaaggtttactctgaatcccaatcctacaggagttcaa
aacccacacatagagagactgagaacacacagcattgagtcatcaggaaaactgaagatc
tcccctgaacaacactgggatttcactgcagaggacttgaaagaccttggagagattgga
cgaggagcttatggttctgtcaacaaaatggtccacaaaccaagtgggcaaataatggca
gttaaaagaattcggtctacagtggatgaaaaagaacaaaagcagcttcttatggatttg
gatgtagtgatgcggagtagtgattgcccatacattgttcagttttatggtgcactcttc
agagagggtgactgttggatctgtatggagctcatgtctacctcgtttgataagttttac
aaatatgtatatagtgtattagatgatgttattccagaagaaattttaggcaaaatcact
ttagcaactgtgaaagcactaaaccacttaaaagaaaacttgaaaattattcacagagat
atcaaaccttccaacattcttctggacagaagtggaaatattaaactctgtgacttcggt
attagtggacagcttgtggactccatcgccaagacaagagatgctgggtgtaggccgtat
atggctcctgaaagaatagacccaagtgcatcacgacaaggatatgatgtccgctctgat
gtctggagtttggggatcacattgtatgagttggccacaggccgatttccttatccaaag
tggaatagtgtatttgatcaactaacacaagtcgtgaaaggagatcctccacagctgagt
aattctgaggagagggagttctccccaagtttcatcaactttgtcaatttgtgccttaca
aaggatgaatccaaaaggccaaagtataaagaacttctgaaacatccctttattttgatg
tacgaggaacgtaccgttgaggtcgcatgctatgtttgtaaaatcctggatcaaatgcca
gctactcccagctctcccatgtatgtcgattga

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