Otolemur garnettii (small-eared galago): 100946793
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Entry
100946793 CDS
T07855
Symbol
HTT
Name
(RefSeq) huntingtin
KO
K04533
huntingtin
Organism
oga
Otolemur garnettii (small-eared galago)
Pathway
oga05016
Huntington disease
oga05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
oga00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05016 Huntington disease
100946793 (HTT)
05022 Pathways of neurodegeneration - multiple diseases
100946793 (HTT)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
oga03019
]
100946793 (HTT)
04131 Membrane trafficking [BR:
oga04131
]
100946793 (HTT)
03029 Mitochondrial biogenesis [BR:
oga03029
]
100946793 (HTT)
Messenger RNA biogenesis [BR:
oga03019
]
Eukaryotic type
mRNA surveillance and transport factors
mRNA cycle factors
Common to processing body (P body) and stress granule
100946793 (HTT)
Membrane trafficking [BR:
oga04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
100946793 (HTT)
Mitochondrial biogenesis [BR:
oga03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
100946793 (HTT)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Htt_C-HEAT
Htt_N-HEAT
Htt_bridge
Htt_N-HEAT_1
HEAT
HEAT_2
HEAT_EF3_N
Rad26-like_helical_rpts
Motif
Other DBs
NCBI-GeneID:
100946793
NCBI-ProteinID:
XP_012667730
Ensembl:
ENSOGAG00000007586
LinkDB
All DBs
Position
Unknown
AA seq
3084 aa
AA seq
DB search
MATLEKLMKAFESLKSFQQQQAVSEEPLHRPKKELSATKKDRVNHCLTICENIVAQSLRN
SPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNKVIKALMDSNLPRLQLELYKEIKKN
GAPRSLRAALWRFAELAHLVRPQKCRPYLVNLLPCLTRTSKRPEESVQETLAAAVPKIMA
SFGNFANDNEIKVLLKAFIANLKSSSPTIRRTAAGSAVSICQHSRRTQYFYSWLLNVLLG
LLVPVEDEHSTLLILGVLLTLRYLVPLLQQQVKDTSLKGSFGVTQKEMEVSPSAEQLVQV
YELTLHHTQHQDHNVVTGALELLQQLFRTPPPELLQALTTPGGLGQLTVAKEESSGRSRS
GSIVELITGGGSSCSPVLSRKQKGRVLLNEEAALEDDSESRSDTSSSAFAASVKDEISGE
LAASSGVSTPGSTGYDIITEQPRSQHTLQADSVDLASCDLTSAATDGDEEDILSHSSSQV
SAVPSDPALDLNDGTQASSPISDSSQTTTEGPDSAVTPSDSSEIVLDGTDSQYLGMQIGQ
PPEEDEESASVLPDEASDAFRNSSMALQQAHLLKNMGHSRQPSDSSIDKFVSRDEVAEPG
DQENKPCRIKGDIGQPADDDSAPLIYCVRLLSASFLLTGEKNVLVPDRDVRVSVKALALS
CIGAAMALHPESFFSKLYKVPLDTMEYPEEQYVSDILTYIDHGDPQVRGATAILCGTLIC
SILGKSRFHVGDWMGTIRTLTGNTFSLVDCIPLLQKTLKDESSVTCKLACTAVRHCVMSL
CSSSYSELGLQLIIDLLALRNSSYWLVRTELLETLAEIDFRLVSFLEAKAENLHRGDHHY
TGLLKLQERVLNNVVIYLLGDEDPRVRHVAAASLMRLVPKLFYKGDQGQADPVVAVARDQ
SSVHLKLLMHETQPPSHFSVSTITRIYRGYNLLPSITDVTMENNLSRIIAAVSQELITST
TRALTFGCCEALCLLSTAFPVCIWSLGWHCGVPPLNTSDDSRKSCTVGMATMILTLLSSA
WFPLDLSAHQDALILAGNLIAASAPKSLRSSWTSEEEAIPTANKQEEVWPALGDRTLVPM
VEQLFSHLLKVINICAHVLDDVAPGPAIKAALPSLTNPPSLSPIRRKGKEKEPGEQASVP
LSPKKGNETSTASRQSDPSGPVTTSKSSSLGSFYHLPSYLKLHDVLKATHANYKVTLDLQ
NSTEKFGGFLRSALDVLSQILELATLQDIGKCVEEILGYLKSCFSREPMMATVCVQQLLK
TLFGTNLASQFDGSSSNPSKSQGRAQRLGSSSARPGLYHYCFMAPYTHFTQALADASLRN
MVQAEQEHDMSGWFDVLQKVSTQLKTNLTSVTKNRADKNAIHNHIRLFEPLVIKALKQYT
TTTSVQLQKQVLDLLAQLVQLRVNYCLLDSDQVFIGFVLKQFEYIEVGQFRESEAIIPNI
FFFLVLLSYERYHSKQIIGIPKIIQLCDGIMASGRKAVTHAIPALQPIVHDLFVLRGTNK
ADAGKELETQKEVVVSMLLRLIQYHQVLEMFILVLQQCHKENEDKWKRLSRQIADIILPM
LAKQQMYIDSHEALGVLNTLFEILAPSSLRPVDMLLRSMFVTPDSMASVSTVQLWISGIL
AILRVLISQSTEDIVLSRIQELAFSPHVVSCPVISRLREGGSNSVLEEHSEGRHVKNLPE
ETFSRFLLQLVGILLEDIVTKQPKVEMSEQQHTFYCQELGTLLMCLIHIFKSGMFRRITA
AATRLFTSDGCDGTFYSLESLNLRVRTMVPTHPALVLLWCQILLLVNHTDHRWWAEVQQT
PRRHSLSSTKLLSPQMSGEEEHSDLADKLGVCNREIVRRGALILFCDYVCQNLHDSEHLT
WLIVNHIQDLISLSQEPPVQDFISAVHRNSAASGLFIQAIQSRCEDLSSPTTLKKTLQCL
EGIHLSQSGAVLTLYVDRLLCTHFRVLARMVDILACRRVEMLLAANLQSSMAQLPGEELN
RIQEYLQRSGLAQRHQRLYSLLDRFRLSTVQDSPSPSPPVSSHPLDGDGHVSLETVSPDK
DWYMCLVKSQCWTRTDSALLEGAELVNRIPSQEMSAFMMNPEFNLSLLAPCLSLGMGEIS
AGQKSPLFEAACEVTLGRVASLVQQLPAVHHVFQPCLPSGPTTYWSKLSDLFGDATWYQS
LTTLARALAQYLMVVSKLPSHLHLPPEKERDTVKFVVMTLEALSWHLIHEQIPLSLDLQA
GLDCCCLALQLPSLWSVIASTESVTHACSLIHCVHFILRAIAVQPGEQLLSPERRPSAPK
DTRGEGEVDPNTQNPQYVTSACEMIAEMVESLQSVLALGHKRNSSVPAFLTPVLKNIVIS
LARLPLVNSYTRVPPLVWKLGWSPKPGGDFGTAYPEIPVEFLQEKEVFKEFIYRINTLGW
TSRTQFEETWATLLGVLVTQPLVMEQEESPPEEDTERTQINVLAVQAITSLVLSAMTVPV
AGNPAVSCLEQQPRNKPLKALDTRFGRKLSVIRGIVEQEIQAMVSKRENIATHHLYQAWD
PVPSLSPATTGALISHDKLLLQINPERELGNMSYKLGQVSIHSVWLGNNITPLREEEWDE
EEEEEADVPAPSSPPTSPVNSRKHRAGVDIHSCSQFLLELYSRWILPSSSARRTPVILIS
EVVRSLLVVSDLFTERNQFEMMYSTLTELRRVHPSEDEILVQYLVPATCKAAAVLGMDKA
VAEPVSRLLESTLRSSHLPSRIGALHGVLYVLECDLLDDTAKQLIPVVSDYLLSNLKGAA
HCVNSHSQQHVLVMCATAFYLVENYPLDVGPEFSASIIQMCGAMLSGSEECTPSVIYHCA
LRGLERLLLSEQLSRLDAESLAKLSVDRVNVHSPHRAMAALGLMLTCMYTGKEKISPGRT
SDPNPTAPDSESVIVAMERVSVLFDRVRKGSPCEARVVARILPQFLADFFPAQDVMNKVI
GEFLSNQQPYPQFMATVVSKVFQTLHSTGQSSMVRDWVMLSLSNFTQRTPVAMATWSLSC
FFVSATTSPWVAAILPHVISRMGKLEQVDVNLFCLVATDFYRHQIEEELDRRAFQSVFEV
VAAPGTPYHRLLTCLQNVHKVTTC
NT seq
9255 nt
NT seq
+upstream
nt +downstream
nt
atggcgaccctggagaagctgatgaaggcctttgagtctctcaagtcttttcagcagcag
caggcggtgtccgaggagccgctgcaccgaccaaagaaagaactttcagctaccaagaaa
gaccgagtgaatcattgtctgacaatatgtgaaaacatagtggcacaatctctcagaaat
tctccagaatttcagaaacttctgggcatcgctatggaactttttctgctgtgcagtgat
gatgcggagtcagatgtcaggatggtggctgatgagtgcctcaacaaagttataaaagct
ttgatggattccaatcttccaagattacagcttgagctctataaggaaattaaaaagaat
ggcgcccctcgaagtttgcgagctgccctgtggaggtttgccgagctggctcacttggtt
cggcctcagaagtgcaggccttacctggtgaaccttctgccatgcctgactcgaacaagc
aagagacctgaggaatcagtccaagagaccttggctgcagctgtgcccaaaattatggct
tcttttggcaattttgcaaatgacaatgaaattaaggttctgttaaaggctttcatagcg
aatctgaagtccagttcccctaccatccggcggacagcagctgggtcagcagtgagcatc
tgtcagcactcacgaagaacacaatacttttatagctggctactgaatgtactcttaggt
ttgctagttcccgttgaagatgaacattccaccctcctgatcctgggtgtgctgctcaca
ctgaggtatttggtgcccttgctgcagcagcaggtcaaagacacaagcctcaaaggcagc
ttcggggtgacgcagaaagagatggaagtctctccctctgcagagcagctggtccaggtg
tatgaactgaccttgcaccacacgcagcaccaagaccacaatgtcgtgactggagccctg
gaactcctgcagcagctcttcagaacccccccgcctgagctgctgcaggctctgactacg
ccgggtggcctggggcagctcactgtggccaaagaagagtctagtgggcgaagtcgtagt
gggagtattgtggagcttataactggagggggttcctcatgcagccctgtcctttcaaga
aaacaaaaaggcagagtgctcttaaatgaagaagcagccttggaagacgactctgaatcg
aggtcagacactagcagctccgcctttgcagcctctgtgaaggatgagatcagtggagag
ctggctgcttcttcaggggtctccactccaggatcaactggctatgacatcatcactgag
cagccacggtcacagcacacgctgcaggcagactcggtagatctggccagctgtgacttg
acgagtgctgccactgatggggatgaggaggacatcctgagccacagctccagccaggtc
agcgctgtcccatctgaccctgccctggatctcaacgatggaacccaggcttcttcaccc
atcagcgacagctcccagaccaccactgaagggcctgattcagctgtgaccccttcggat
agttctgaaattgtgttagatggtactgacagccagtatttgggcatgcagatcggacag
ccccctgaggaagacgaggaatctgccagtgttcttcctgatgaagcctcggatgctttc
agaaactcttcgatggcccttcaacaagcacatttattgaaaaacatgggtcacagcagg
cagccttctgacagcagtatagataaatttgtgtcaagagatgaagttgctgaaccaggt
gatcaagaaaacaagccttgccgcatcaaaggtgacataggacagcctgctgatgatgat
tctgcgcctctcatctattgtgtccgccttttatctgcttcatttttgctaacgggagaa
aagaatgtgcttgttccggacagggacgtgagagtcagtgtcaaggccctggccctcagc
tgtatcggggcagccatggcccttcatccagaatctttctttagcaaactgtataaagta
cctcttgacaccatggaataccctgaggagcagtatgtctcagacatcctgacctacatt
gatcatggagacccacaggtccgaggagccactgccatcctctgtgggaccctcatctgc
tccatcctcggcaaatcccgcttccatgtgggagactggatgggcaccattagaactcta
acaggaaatacattttctctggtggactgcattcctttgttgcagaaaactctgaaggat
gagtcttctgttacttgcaagttggcttgtacagctgtgaggcattgtgtcatgagtctg
tgcagtagcagctatagtgaattagggttacagctgatcatcgatttgctggccctgagg
aatagctcctactggctggtgaggacagaacttttggaaactcttgcagagattgacttc
aggctggtgagctttttggaggcaaaagcagaaaacttgcacagaggggatcatcattac
acagggcttttaaaactgcaagaacgagtgctcaataatgttgtcatctatttgctgggg
gatgaagaccccagagtgcgacatgtggctgcggcatcattaatgaggcttgtcccaaag
ctgttttataaaggtgaccaaggacaagctgatcccgtagtggccgtggcaagagatcaa
agcagtgttcacctgaaacttctcatgcacgagacacagcctccatctcacttctctgtc
agcacgataaccagaatatacagaggctataacttactaccaagcataacagatgtcacg
atggaaaataatctctcaagaattattgcagcagtttctcaggaactaatcacatcaacc
acaagagcactcacatttggatgctgtgaagccttgtgtcttctttcaaccgccttccca
gtttgcatttggagtttaggttggcactgtggagtaccccccctgaacacctcagatgat
tctagaaagagctgtacggttgggatggccacaatgattcttaccctgctttcatcagct
tggttcccgttggatctctcggcccatcaagatgctttgattttggctggaaatttgatt
gcagccagtgcccccaaatctctgagaagttcatggacctctgaagaagaagccatccca
acagccaataagcaagaggaggtctggccagccctgggtgaccggaccctggtgcccatg
gtggagcagctcttttcccacctgctgaaggtgattaatatctgtgctcatgtcttggat
gatgtggctcctggaccagcaataaaggcagccttaccttctctaacaaaccccccttct
ctaagtcccatccgacgaaagggaaaggagaaagaaccaggagaacaggcatctgtccca
ctgagtcccaagaaaggcaacgagaccagcacagcctccagacaatctgatccttcaggg
cctgtgacaacaagcaaatcctcatcactggggagtttctaccatctcccttcatacctc
aaattgcatgacgtcctgaaagctactcacgccaactacaaggttaccttggatcttcag
aacagcactgaaaagtttgggggattcttgcgctccgcgttggacgttctctctcagatt
ttggagctggcaacactacaggacattgggaagtgtgttgaagaaatcctggggtatctg
aagtcctgctttagtcgagagccaatgatggcaactgtctgtgtccaacagttgttgaag
actctttttgggacaaacttggcctcccagtttgatggctcatcttccaaccccagcaag
tctcaaggccgagcacagcggcttggctcctccagtgcaaggccaggcttgtaccactac
tgcttcatggctccatacacccacttcacccaggcccttgctgatgccagcctgaggaac
atggtgcaggcggagcaggaacacgacatgtctggatggtttgatgtactccagaaagta
tctacccaattgaaaacaaatctcacaagtgtcacaaagaaccgtgcagataagaatgct
atacataatcacattcgtttatttgagcctcttgttataaaagctttaaaacagtacaca
acaacaacatctgtgcaattacagaagcaggttttagatttgctggcgcaactggttcag
ttacgggttaattactgtcttctggattcagatcaggtgtttattggctttgttttgaaa
cagtttgaatacattgaagtgggccagttcagggaatcagaggcaattattcctaacatc
tttttcttcctggtgttactgtcttatgagcgctatcattcaaaacagatcattggaatt
cctaaaatcattcagctctgtgatggcatcatggccagtgggaggaaggcggtgacacac
gccataccagccctgcagcccattgtccacgacctctttgtattaagagggacaaataaa
gctgatgcaggaaaagagcttgaaactcagaaagaagtggtagtctcaatgctactcaga
ctcatccagtaccatcaggtgctggagatgttcattctcgtcttacagcagtgtcacaag
gagaatgaagacaaatggaagcggctgtctcgacagatagcagacatcatcctccccatg
ttagccaaacagcagatgtacattgactctcatgaagcccttggcgtgttaaatacttta
tttgagattttggccccttcctcactccggccggtggacatgctattacggagtatgttt
gtcaccccagactcaatggcatctgtgagcactgttcagctgtggatatcagggatccta
gccattttgcgggttctgatttctcagtcgactgaggacattgtcctctctcgaattcag
gagcttgccttctctccacatgtagtgtcctgccccgtgatcagtaggttaagagaaggt
gggagtaactcagtgctagaagagcacagtgaagggagacatgtgaagaacttgccagaa
gaaacattctcaaggtttctgttacagctggttggtattcttttagaggacattgttacc
aaacagcccaaggtggaaatgagtgaacagcaacatactttctactgccaagaactaggc
acactgctgatgtgtctgatccacatcttcaagtccggaatgttccggagaatcacagca
gctgccactagactgttcaccagtgatggctgtgacggcactttctacagcctggagagc
ctaaaccttcgagtgcgcaccatggtccccacacacccggccctggtgctgctgtggtgt
cagatcctgctgcttgtcaaccacactgaccaccgctggtgggcagaggtgcagcagacc
ccaagaagacacagtctgtccagcacgaagttacttagtccccagatgtctggagaagag
gagcattctgacttggcagacaaacttggagtgtgcaatagagagatagtgcgaagagga
gctcttattctcttctgcgattatgtgtgtcagaacctccatgactcagagcacttaacg
tggctcattgtgaatcacattcaagatctaattagcctgtcccaggagcctccagtgcaa
gacttcattagcgccgttcatcgcaattctgctgctagtggtctattcatccaggccatc
cagtctcgctgtgaggacctctcgtccccaaccactctgaagaaaactctgcagtgcctg
gaagggatccatctcagccagtcaggtgctgtgctcacgctgtatgtggacaggcttctg
tgtacccacttccgtgtgctggctcgcatggtggacatccttgcctgtcgccgggtagaa
atgcttttggctgcaaatttacagagcagcatggcccagttgccaggggaagaactcaac
agaatccaggagtaccttcagcgcagtgggctggcccagagacaccaaaggctctattcc
ttgctggacaggtttcgtctttccactgtacaggactcacccagtccctctcctccagtc
tcttcccacccgctggatggggatgggcatgtatcactggaaacagtgagtccagacaaa
gactggtacatgtgtcttgtcaaatcccagtgttggactaggacagattctgcactgctg
gaaggtgcagagctggtgaatcggattccttcccaagaaatgagtgccttcatgatgaac
ccggagttcaacctaagcctattagctccatgcttaagcctaggcatgggtgagatttct
gctggccagaagagtcctctttttgaagcagcctgtgaagtgactctgggccgtgtggcc
agccttgttcagcagcttcctgctgtccaccatgtcttccagccctgcctcccttcaggg
cccacaacttactggagcaagctgagtgatctatttggggatgccacgtggtatcagtcc
ctgaccacactggctcgggccctggcacagtacctgatggtggtctccaagctacccagt
catctgcaccttcctccggagaaggagagggacacagtcaagtttgtggtgatgaccctc
gaggccctgtcatggcatctaatccacgagcagatcccactgagtctggacctccaagca
gggctggactgctgctgcctggctctacagctgcccagcctctggagtgtaatcgcctcc
acagagtccgtgacccacgcctgctccctcatccactgtgtgcacttcatcttgcgagcc
attgccgtgcagcctggagagcagcttcttagtccagaaagaaggcccagcgcaccgaag
gacaccagaggggagggtgaagtggatcccaacacacagaatccccagtatgtcacctca
gcctgcgagatgatagcagaaatggtggagtctctgcagtcggtattggccttgggtcac
aagaggaatagcagtgtgccagcgtttctcacccctgtgctcaagaatatcgtcatcagc
ctggcccgcttacccctcgtcaacagctacacgcgtgtgccccccctggtgtggaagctt
gggtggtcacccaaaccaggaggggattttggcacagcatacccagagatccccgtggag
tttctccaagaaaaagaagtcttcaaggagttcatctaccgaatcaacacactaggatgg
accagtcgtacccagtttgaagaaacgtgggccaccctccttggtgtcctggtgacccag
ccccttgtgatggaacaggaggagagcccaccagaggaagacacggaaaggacccagatt
aatgtcctggccgtgcaagccatcacctccctggtgctcagtgcgatgactgtgcctgtg
gccggcaacccagctgtgagctgcttggagcagcagccgcgaaacaagcccctgaaagct
ctggacaccaggtttgggaggaagctgagtgttatccgtgggattgttgagcaggagatt
caagcaatggtttcaaagcgagagaacattgccactcatcatttgtaccaggcgtgggat
cctgtcccttctctgtctccggccactacaggtgcactcatcagccacgacaagctgctg
ttgcagatcaaccctgagcgggagctggggaacatgagctacaagctcggccaggtgtcc
atacactctgtgtggctggggaacaacatcacacccctgagggaagaggagtgggatgag
gaagaggaggaggaggctgatgtcccggcaccatcatcaccacccacatctccagtcaac
tccaggaagcaccgggctggcgttgacatccactcctgctcccagttcctgcttgagttg
tatagtcgctggatcctaccatcgagctcagccagaaggacccctgtcatcctgatcagt
gaagtggttcgatcgcttctagtggtctcagacttgttcaccgaacgcaatcagtttgag
atgatgtattcaacgctgacagagctgcggcgggtacacccttcagaggacgagattctt
gttcaatatttggtgccggccacctgtaaggcggctgctgtcctcgggatggacaaggct
gtggcagagccagtcagccgcctgctagaaagcacgctcaggagcagccacctgcccagc
aggataggagccctgcatggtgtcctctacgtgctggagtgcgacctgctggatgacacg
gcaaagcagctgatcccagtcgtcagtgactatctcctctccaacctcaagggagcagcc
cactgcgtgaacagtcacagtcagcagcatgtgctggtgatgtgtgctactgccttctat
ttggttgagaactaccctctggatgtggggccagaattttcggcgtcaataatacagatg
tgtggggcaatgttgtctggaagcgaggagtgtaccccctccgtcatctaccactgcgcc
ctcaggggcctggagcgcctcctactctctgagcagctctcacggctggacgcagagtcc
ctggccaagctgagcgtggacagagtgaacgtgcatagcccacaccgggccatggcagcc
ctgggcctgatgctcacctgcatgtacacaggaaaggaaaaaatcagtccgggtagaacc
tcagaccctaaccctacagccccagacagcgagtcggtgattgtggctatggagcgagtg
tctgtcctttttgatagggtcaggaaggggtctccctgtgaagccagagtggtggccagg
atcctgcctcagtttctagctgacttcttcccagcccaggacgtcatgaacaaggtcatc
ggagagtttctatccaaccagcagccttacccacagttcatggccaccgtggtgtccaag
gtgtttcagacactacacagcaccggacagtcatccatggttcgcgactgggtcatgctg
tccctctccaacttcacacagaggaccccggtcgccatggccacatggagtctctcctgc
ttctttgtcagtgcaaccaccagcccctgggtcgcagcaatccttccacacgtaatcagc
aggatgggcaagctggagcaggtggatgtgaaccttttctgcctggttgccacagacttt
tacagacaccagatagaagaggagctcgaccgcagggccttccagtctgtgtttgaggtg
gtcgcagctccaggaaccccataccaccggctgctgacttgtttgcaaaacgtccacaaa
gtcaccacctgctaa
DBGET
integrated database retrieval system
