Otolemur garnettii (small-eared galago): 100947434 Help Entry 100947434         CDS       T07855                                  Symbol TOP2A Name (RefSeq) DNA topoisomerase 2-alpha   KO K03164   DNA topoisomerase II [EC:5.6.2.2] Organism oga  Otolemur garnettii (small-eared galago) Pathway oga01524   Platinum drug resistance Brite KEGG Orthology (KO) [BR:oga00001]  09160 Human Diseases   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     100947434 (TOP2A)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03032 DNA replication proteins [BR:oga03032]     100947434 (TOP2A)    03036 Chromosome and associated proteins [BR:oga03036]     100947434 (TOP2A) Enzymes [BR:oga01000]  5. Isomerases   5.6  Isomerases altering macromolecular conformation    5.6.2  Enzymes altering nucleic acid conformation     5.6.2.2  DNA topoisomerase (ATP-hydrolysing)      100947434 (TOP2A) DNA replication proteins [BR:oga03032]  Eukaryotic type   DNA Topoisomerases    100947434 (TOP2A) Chromosome and associated proteins [BR:oga03036]  Eukaryotic type   Chromosome condensation proteins    Other regulators of chromosome condensation     100947434 (TOP2A)   Centrosome formation proteins    Centriole proteins     100947434 (TOP2A) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  DNA_topoisoIV TOPRIM_C DNA_gyraseB DTHCT HATPase_c Toprim Microp_apicomplexa_20 Motif Other DBs NCBI-GeneID:  100947434 NCBI-ProteinID:  XP_003786441 Ensembl:  ENSOGAG00000001638 UniProt:  H0WJ18 LinkDB All DBs Position Unknown AA seq 1533 aa AA seqDB search MEVSPLQPVNENMQIDKIKKNGDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVELVTQQ MWVYDEDVGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDSENNLISIWN NGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVE TASREYKKMFKQTWKDNMGRSGEMELKPFNGEDYTCITFQPDLSKFKMQSLDKDIVALMV RRAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDMYLKDKVDETGNPLKVIHEQVNQRWEVC LTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVTKLVDVVKKKNKGGVAVKAHQVKNHM WIFVNALIENPTFDSQTKENMTLQAKSFGSTCQLSEKFIKAAVGCGIVESILNWVKFKAQ VQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSTDCTLILTEGDSAKTLAVSGLGVVGRDK YGIFPLRGKLLNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMT DQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEIAFYSIPEFEEWKN STPNYKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQVDD RKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVD GLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNN LNLLRPIGQFGTRLHGGKDSASPRYIFTMLSSLARLLFPPKDDHTLKFLYDDNQRVEPEW YIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLPMLPSYKNFKGTIE ELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYKEY HTDTTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILR DFYELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQR GYDSDPVKAWKEAQQKVPDEDENEESDTEKDTEKSDSVTDSGPTFNYLLDMPLWYLTKEK KDELCKLRNEKEQELDTLKKKTPADLWKEDLAVFIEELEAVEAKEKQDEQVGLSGKGGKA KGKKTQMAEVLPSPHGKRVIPQVTTEMKAEAEKKNKKKIKSENTEGRPQEDGIELESLKQ RLEKKLKREPGTKTKKQTTLPFKPISKGKKKNPWSDSESDMSSNESNFDLPAREKKPRAV STKAKFTMDLDSDEDFSDFDKETNQDEDYVLSDASPPKTKTSPKHTDRELKPQKSAMSEK NLEANDKDSVQLSSSPPASDFSAETEIINPDSKKNVTVKKTTAKSQSSTSTTGAQKRAAP KGTKRNPALKSGVSEKPDLAKTKNQRKRKPSTSDDSDSSFKKIISKAVTSKKPKGESDDF HLDFDSTVSPRGKSRRAKKPIKYIEESDEDDLF NT seq 4602 nt NT seq  +upstreamnt  +downstreamnt atggaggtgtccccgctacagcctgtaaatgaaaacatgcaaattgacaaaataaagaag aatggagatgccaagaaaagactgtctattgaaaggatctatcaaaagaaaacgcaattg gaacatattttgctccgcccagacacctacattggctctgtggaattagtgacccagcaa atgtgggtttatgatgaagatgttggcattaactacagggaagtcacttttgttcctggt ttgtacaaaatctttgatgagattctagtaaatgctgcggacaacaaacaacgggacccc aaaatgtcttgtattagagtcacaattgactcggaaaacaatttgatcagtatatggaat aatggaaaaggtattcctgttgttgaacacaaagttgagaagatgtatgtcccagctctc atatttggacagctcctaacttctagtaactatgatgatgatgaaaagaaagtaacaggt ggtcgaaatggctatggagccaaattgtgtaatatattcagtaccaaatttactgtggaa acagctagtagagaatacaagaaaatgttcaaacagacatggaaggataacatggggaga agtggtgaaatggaactcaagccctttaatggagaagattatacatgtatcaccttccag cctgacttgtctaagtttaaaatgcagagcctggacaaagacattgtggcactgatggtt agacgagcatatgatattgctggatccaccaaagatgtgaaagtctttcttaatggaaat aagttgccagtaaaaggatttcgtagttatgtggatatgtatttgaaagataaagtagat gaaactggcaacccattgaaagtaatacatgaacaagtaaaccagcgatgggaagtgtgt ttaacaatgagtgaaaaaggctttcagcaaattagctttgtcaacagcattgctacttcc aagggtggcagacatgttgattatgtagctgatcagattgtgactaaacttgttgatgtc gtgaagaagaagaacaagggtggtgttgcagtaaaagcacatcaggtgaaaaatcacatg tggatttttgtgaatgccttaattgaaaacccaacctttgactctcagacaaaagaaaat atgactttacaagccaagagctttggatcaacatgccaattaagtgaaaaattcatcaaa gctgcagttgggtgtggtattgtagaaagcatactaaactgggtgaagtttaaggcccaa gtccagttaaacaagaagtgttcagctgtaaaacataacagaatcaagggaattcccaaa cttgatgatgccaatgatgcagggggccgaaactccactgactgtacacttatcctaact gaaggagactcagccaaaactttggccgtttcaggccttggtgtggttgggagagataaa tatgggattttccctcttagaggaaaattactcaatgttcgagaagcttctcataaacag atcatggaaaatgctgaaataaacaatatcatcaagattgtaggtctacagtacaagaaa aactatgaagatgaagattcattgaagactcttcgttacgggaagataatgattatgaca gatcaggaccaagatggttcccatatcaaaggcttgctaattaattttatccatcacaac tggccctctcttctgcgacatcgtttcttggaggaatttatcactcccattgtaaaggtg tctaaaaataagcaagaaatagcattctatagtattcctgaatttgaagaatggaagaac tctacaccaaattataaaaaatggaaagtcaagtattacaaaggtttaggcactagcaca tcaaaggaagcaaaagaatactttgcagatatgaaaagacatcgtatccaattcaaatat tcaggtcctgaagatgatgctgcaatcagcctggcctttagcaaaaaacaggtagatgat cgaaaggaatggttgactcatttcatggaagatagaagacaacgcaagttacttggcctt cctgaggattacttatatgggcaaactaccacatatctgacatataatgacttcataaac aaggaacttatcttgttctcaaattctgataatgagagatctatcccatctatggtggat ggtttgaaaccaggtcagagaaaggttttgtttacttgtttcaaacggaatgacaagcga gaggtaaaggttgcccagttagctgggtcagtggctgaaatgtcttcttatcatcatggt gagatgtcactaatgatgaccattatcaatttggctcagaattttgtgggtagtaataat ctaaacctcttgcggcctattggtcagtttggtaccaggctacatggtggtaaggattct gccagtcctcgatacattttcacaatgcttagctctttggctcggttgttatttccacca aaagatgatcacacattaaagttcttgtatgatgacaaccaacgagttgaacctgaatgg tacattcctataatacctatggtactaataaatggtgctgaaggaataggtactgggtgg tcctgcaaaatccccaactttgatgttcgtgaagttgtaaataacatcaggcgtttgatg gatggagaagaacctctgccaatgcttccaagttacaagaacttcaagggtactattgaa gagctggctccaaatcaatacgtaattagtggtgaagtagctattcttaattccacaacc attgaaatctcagagcttcccatcagaacatggacccaaacctataaggagcaggttcta gaacccatgttgaatggcactgagaagacacctcctctcataacagactataaggaatac catacagataccactgtgaagtttgttgtaaagatgactgaagaaaaactggcagaggca gagagagttggattgcataaagtcttcaaactccaaactagtctcacatgcaactctatg gtactttttgaccacgtgggctgtttaaagaaatatgacacagtgttggatattctaaga gacttctatgaactcaggcttaaatattatgggctaagaaaagaatggcttttaggaatg cttggtgctgaatctgctaaactgaacaatcaggctcgctttatattagagaaaatagat ggcaaaataatcattgaaaataagcctaagaaagaattaattaaagttctgattcagagg ggatatgattcggatcctgtgaaggcctggaaagaagcccagcaaaaggttccagatgaa gacgaaaatgaagagagtgacaccgaaaaggacactgaaaaaagtgactctgtaacagat tctggaccaactttcaactacctacttgatatgcccctttggtatctaaccaaagaaaag aaagatgaactatgcaaactaagaaatgaaaaagagcaagagctggacacattgaagaaa aagactccagcagatttgtggaaagaagacttagctgtttttattgaagaactagaggct gtagaagccaaggaaaaacaagatgaacaagttggactttctgggaaagggggaaaagca aaggggaaaaaaacacaaatggctgaagttttgccttctccacatggaaaaagagtcatt ccccaagttaccacagaaatgaaagcagaggcagaaaagaaaaataaaaagaaaattaag agtgaaaatactgaaggaaggcctcaagaggatggtatagaattagaaagcctaaaacaa aggttagagaagaaactgaaaagagaaccaggtaccaagacaaagaaacaaactacactg ccatttaaaccaatctcaaaaggaaagaagaaaaatccctggtctgattcagaatccgat atgagcagtaatgaaagtaattttgatctccctgcacgagaaaaaaagccccgggcagta tcaacaaaagccaaattcacaatggatttggactcagatgaagatttctcagattttgat aaagaaacaaatcaagatgaagattatgtcttgtcagatgctagtccaccaaaaaccaaa acttccccaaaacatactgacagagaactgaagccacagaagagtgccatgtcagaaaag aaccttgaggctaatgataaagacagtgtacaactttcttcaagccctcctgcttctgat ttctcagctgaaactgaaattataaacccagattctaaaaagaatgtgacagtgaagaag acaacagcaaaaagtcagtcttctacctccaccaccggtgcccaaaaaagggctgctcca aaaggaaccaaaaggaatccagccttgaaatctggtgtctctgaaaagcctgatcttgcc aaaactaagaatcaacgcaaaaggaagccatctacttctgatgattctgactctagtttt aagaaaattatttctaaagcagtcacaagcaaaaaacccaagggggagagtgatgacttc cacctggattttgactcaacagtgtctcctcggggaaaatccagacgggcaaagaaacct ataaagtatattgaagagtcggatgaagatgatctattttaa

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