Otolemur garnettii (small-eared galago): 100948875
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Entry
100948875 CDS
T07855
Symbol
JAK2
Name
(RefSeq) tyrosine-protein kinase JAK2 isoform X1
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
oga
Otolemur garnettii (small-eared galago)
Pathway
oga01521
EGFR tyrosine kinase inhibitor resistance
oga04062
Chemokine signaling pathway
oga04081
Hormone signaling
oga04148
Efferocytosis
oga04151
PI3K-Akt signaling pathway
oga04217
Necroptosis
oga04550
Signaling pathways regulating pluripotency of stem cells
oga04630
JAK-STAT signaling pathway
oga04658
Th1 and Th2 cell differentiation
oga04659
Th17 cell differentiation
oga04725
Cholinergic synapse
oga04917
Prolactin signaling pathway
oga04920
Adipocytokine signaling pathway
oga04933
AGE-RAGE signaling pathway in diabetic complications
oga04935
Growth hormone synthesis, secretion and action
oga05140
Leishmaniasis
oga05145
Toxoplasmosis
oga05152
Tuberculosis
oga05161
Hepatitis B
oga05164
Influenza A
oga05167
Kaposi sarcoma-associated herpesvirus infection
oga05168
Herpes simplex virus 1 infection
oga05200
Pathways in cancer
oga05207
Chemical carcinogenesis - receptor activation
oga05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
oga05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
oga00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
100948875 (JAK2)
04151 PI3K-Akt signaling pathway
100948875 (JAK2)
09133 Signaling molecules and interaction
04081 Hormone signaling
100948875 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
100948875 (JAK2)
09143 Cell growth and death
04217 Necroptosis
100948875 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
100948875 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
100948875 (JAK2)
04659 Th17 cell differentiation
100948875 (JAK2)
04062 Chemokine signaling pathway
100948875 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
100948875 (JAK2)
04917 Prolactin signaling pathway
100948875 (JAK2)
04935 Growth hormone synthesis, secretion and action
100948875 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
100948875 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100948875 (JAK2)
05207 Chemical carcinogenesis - receptor activation
100948875 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100948875 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
100948875 (JAK2)
05164 Influenza A
100948875 (JAK2)
05168 Herpes simplex virus 1 infection
100948875 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
100948875 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
100948875 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
100948875 (JAK2)
05140 Leishmaniasis
100948875 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100948875 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
100948875 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100948875 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oga01001
]
100948875 (JAK2)
Enzymes [BR:
oga01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
100948875 (JAK2)
Protein kinases [BR:
oga01001
]
Non-receptor tyrosine kinases
JAK family [OT]
100948875 (JAK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
SH2
ABC1
FERM_C_FAK1
RIO1
Kinase-like
Motif
Other DBs
NCBI-GeneID:
100948875
NCBI-ProteinID:
XP_003782949
Ensembl:
ENSOGAG00000012246
LinkDB
All DBs
Position
Unknown
AA seq
1132 aa
AA seq
DB search
MGMACLTMTEMERASTSSVHQNGDISGNVSSVKQIDPVLQVYLYHSLGRAEGDYLKFPTG
EYVAEEICIAASKACGITPVYHNMFALMCETERIWYPPNHVFHIDDSTRHNVLYRIRFYF
PHWYCSGTNRTYRHGISRGAEAPLLDDFVMSYLFAQWRHDFVYGWIKVPVTHETQEECLG
MAVLDMMRIAKEKDQTPLAIYNSISYKTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQQF
SQCKATARNLKLKYLINLETLQSAFYTEQFEVKEHGRGPSGEEIFATIIITGNGGIQWSR
GKHKESETLTEQDLQLYCDFPNIIDVSIKQANQEGSNESRVVTIHKQDGKNLEIEIGSLR
EALSFVSLIDGYYRLTVDAHHYLCKEVAPPTVLENIQSNCHGPISMDFAISKLKKAGNQT
GLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENGEYNLSGTKKNFNNLKDLLNC
YQLETVRSDSIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPNSPALQRHNNVNQMVFHKI
RNEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASM
MSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNCINILWKLEVAKQLAWA
MLFLEEKTLIHGNVCAKNILLIREEDRKTGNPPFVKLSDPGISITVLPKDILQERIPWVP
PECIENPKNLRLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWTEL
ANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRD
PTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIE
ILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQI
CKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFW
YAPESLTESKFSVASDVWSFGVVLYELFTYIDKSKSPPAEFMRMIGNDKQGQMIVFHLIE
LLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNMTG
NT seq
3399 nt
NT seq
+upstream
nt +downstream
nt
atgggaatggcttgccttacaatgacagaaatggaaagagcatccacatcttctgtacat
caaaatggtgatatttctggaaatgtcagttctgtgaagcaaatagatccagtcctgcag
gtgtatctttaccattcccttgggagagctgagggagattacctaaagtttccaactgga
gagtatgttgcagaagaaatttgtattgctgcttctaaggcttgtggtattacacctgtg
tatcataatatgtttgctttaatgtgtgaaacagaaaggatctggtacccacccaaccat
gtcttccatatagatgactcaaccaggcataatgtgctctacagaataagattttatttc
cctcactggtattgcagtggcaccaacagaacctatcggcatgggatatctcgaggtgct
gaagctcctcttcttgatgactttgtcatgtcttacctttttgctcagtggcgccatgat
tttgtgtatggttggataaaagtacctgtgactcatgaaacacaggaagaatgtcttggg
atggctgtgttagatatgatgagaatagccaaagaaaaggatcaaactccacttgccatt
tataactctatcagctacaagacattcttaccaaaatgtatacgagcgaagatccaagac
tatcatattttgacaaggaaacgaataaggtacagatttcgcagatttattcagcagttc
agccaatgcaaagccactgccagaaacttgaaacttaagtatcttataaatctggaaact
cttcagtctgccttctacacagagcagtttgaagtaaaagaacatggaagaggtccttca
ggtgaggagatttttgcaaccattataataactggaaacggtggaattcagtggtcaaga
gggaaacataaagaaagtgagacactgacagaacaggatttacagttatattgtgatttt
cctaatattattgatgtcagtattaagcaagcaaaccaagaaggctcaaatgaaagcaga
gttgtaactatccataagcaagatggtaaaaatttggaaattgaaattggttcattaaga
gaagctttgtcttttgtgtcattaattgatggatattatagattaactgtagatgcacat
cattacctctgtaaagaagtagcacctccaacagtgcttgaaaatatacaaagcaactgt
catggcccaatttcaatggattttgccataagtaaactgaagaaagcaggtaatcagact
ggactgtatgtacttcgatgcagtcctaaggactttaataagtattttctgacttttgct
gttgagcgagaaaatgtcattgaatataaacactgtttgattacaaaaaatgagaatgga
gaatacaacctcagtgggactaagaagaactttaataatcttaaagatcttttgaattgc
taccagttggaaactgttcgctctgatagtataattttccagtttactaagtgctgtcct
ccaaagccaaaagataaatcaaaccttctagtctttagaaccaatggtgtttctgacgta
ccaaactcaccagcattacagaggcataataatgtgaaccaaatggtgtttcacaaaatc
agaaatgaagatttgatatttaatgaaagcctgggccaaggtacttttacaaaaattttt
aaaggtgtaagaagagaagtaggagactatggtcaattgcatgaaacggaagttctttta
aaagttctggataaagcacacagaaactattctgagtctttctttgaagcagcaagcatg
atgagccagctttctcacaagcatctggttttaaattatggagtatgtgtctgtggggag
gaaaatattctggttcaggagtttgtaaaatttggatcattagatacatatctgaaaaag
aacaaaaactgtataaatatattatggaaacttgaagtggctaagcagttggcatgggcc
atgctttttctggaagaaaaaacccttattcatggaaatgtctgtgccaaaaatattctg
cttatcagagaagaagacaggaaaacaggaaatcctcctttcgtcaaacttagtgaccct
ggcattagtattacagttttgccaaaggacattcttcaggagagaataccatgggtacca
cctgaatgcatcgaaaatcctaaaaatctacgcttggcaacagacaaatggagttttggt
accactttgtgggaaatatgcagtggaggagataagcctctgagtgctctggactcccaa
agaaagctgcagttttatgaagataggcaccagcttcctgcaccaaagtggacagaatta
gcaaaccttataaataattgtatggattatgaaccagattttaggccttctttcagagcc
atcatacgagatcttaacagtttgtttactccagattatgaactattaacagaaaatgac
atgttaccaaatatgaggataggtgccctaggcttttctggtgcttttgaagacagggac
cctacacagtttgaagagagacatttgaaatttctacagcaacttggcaagggtaatttt
ggaagtgtggagatgtgccggtatgaccctctacaagacaacactggggaggtggtggct
gtaaaaaagcttcagcacagtactgaagagcacctaagagactttgaaagggaaattgaa
atcctgaaatctctgcagcatgacaacattgtaaagtacaagggagtgtgctacagtgct
ggccggcgtaatttaagattaattatggaatatttaccatatggaagtttacgagactat
ctccaaaaacataaagaacgaatagatcacaaaaaacttctacagtacacatctcagata
tgcaagggtatggagtatcttggtacaaaaaggtatatccatagggatctggcaacaaga
aatatattggtggagaatgagaacagagttaaaattggagattttggcttaaccaaagtc
ttgccacaagacaaagaatactacaaagtaaaagaacctggtgaaagtcccatattttgg
tatgctccagaatcactgacagagagcaaattttctgtggcctcagatgtttggagcttt
ggagtggttctgtatgaacttttcacatatattgataaaagtaaaagtccaccagcggaa
tttatgcgtatgattggcaatgacaaacaagggcagatgattgtgttccatttgatagag
ctcctaaagaataatggacgattgccaagaccagatggatgcccagatgagatttatatg
atcatgacagaatgctggaacaataacgtaaatcaacgtccctcctttagggacctagct
cttcgagtggatcaaataagggacaacatgactggatga
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integrated database retrieval system
