Otolemur garnettii (small-eared galago): 100949638 Help Entry 100949638         CDS       T07855                                  Symbol ADCY4 Name (RefSeq) adenylate cyclase type 4   KO K08044   adenylate cyclase 4 [EC:4.6.1.1] Organism oga  Otolemur garnettii (small-eared galago) Pathway oga00230   Purine metabolism oga01100   Metabolic pathways oga01522   Endocrine resistance oga04015   Rap1 signaling pathway oga04020   Calcium signaling pathway oga04022   cGMP-PKG signaling pathway oga04024   cAMP signaling pathway oga04062   Chemokine signaling pathway oga04072   Phospholipase D signaling pathway oga04081   Hormone signaling oga04082   Neuroactive ligand signaling oga04114   Oocyte meiosis oga04211   Longevity regulating pathway oga04213   Longevity regulating pathway - multiple species oga04261   Adrenergic signaling in cardiomyocytes oga04270   Vascular smooth muscle contraction oga04371   Apelin signaling pathway oga04540   Gap junction oga04611   Platelet activation oga04713   Circadian entrainment oga04714   Thermogenesis oga04723   Retrograde endocannabinoid signaling oga04724   Glutamatergic synapse oga04725   Cholinergic synapse oga04727   GABAergic synapse oga04742   Taste transduction oga04750   Inflammatory mediator regulation of TRP channels oga04911   Insulin secretion oga04912   GnRH signaling pathway oga04913   Ovarian steroidogenesis oga04914   Progesterone-mediated oocyte maturation oga04915   Estrogen signaling pathway oga04916   Melanogenesis oga04918   Thyroid hormone synthesis oga04921   Oxytocin signaling pathway oga04923   Regulation of lipolysis in adipocytes oga04925   Aldosterone synthesis and secretion oga04926   Relaxin signaling pathway oga04927   Cortisol synthesis and secretion oga04928   Parathyroid hormone synthesis, secretion and action oga04934   Cushing syndrome oga04935   Growth hormone synthesis, secretion and action oga04970   Salivary secretion oga04971   Gastric acid secretion oga04972   Pancreatic secretion oga04976   Bile secretion oga05032   Morphine addiction oga05163   Human cytomegalovirus infection oga05166   Human T-cell leukemia virus 1 infection oga05200   Pathways in cancer oga05207   Chemical carcinogenesis - receptor activation oga05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:oga00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     100949638 (ADCY4)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     100949638 (ADCY4)    04072 Phospholipase D signaling pathway     100949638 (ADCY4)    04024 cAMP signaling pathway     100949638 (ADCY4)    04022 cGMP-PKG signaling pathway     100949638 (ADCY4)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     100949638 (ADCY4)    04081 Hormone signaling     100949638 (ADCY4)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     100949638 (ADCY4)    04062 Chemokine signaling pathway     100949638 (ADCY4)   09152 Endocrine system    04911 Insulin secretion     100949638 (ADCY4)    04923 Regulation of lipolysis in adipocytes     100949638 (ADCY4)    04913 Ovarian steroidogenesis     100949638 (ADCY4)    04915 Estrogen signaling pathway     100949638 (ADCY4)    04921 Oxytocin signaling pathway     100949638 (ADCY4)    04926 Relaxin signaling pathway     100949638 (ADCY4)    04935 Growth hormone synthesis, secretion and action     100949638 (ADCY4)    04918 Thyroid hormone synthesis     100949638 (ADCY4)    04928 Parathyroid hormone synthesis, secretion and action     100949638 (ADCY4)    04925 Aldosterone synthesis and secretion     100949638 (ADCY4)    04927 Cortisol synthesis and secretion     100949638 (ADCY4)   09154 Digestive system    04970 Salivary secretion     100949638 (ADCY4)    04971 Gastric acid secretion     100949638 (ADCY4)    04972 Pancreatic secretion     100949638 (ADCY4)    04976 Bile secretion     100949638 (ADCY4)   09156 Nervous system    04724 Glutamatergic synapse     100949638 (ADCY4)    04727 GABAergic synapse     100949638 (ADCY4)    04725 Cholinergic synapse     100949638 (ADCY4)    04723 Retrograde endocannabinoid signaling     100949638 (ADCY4)   09157 Sensory system    04742 Taste transduction     100949638 (ADCY4)    04750 Inflammatory mediator regulation of TRP channels     100949638 (ADCY4)   09149 Aging    04211 Longevity regulating pathway     100949638 (ADCY4)    04213 Longevity regulating pathway - multiple species     100949638 (ADCY4)   09159 Environmental adaptation    04713 Circadian entrainment     100949638 (ADCY4)    04714 Thermogenesis     100949638 (ADCY4)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100949638 (ADCY4)    05207 Chemical carcinogenesis - receptor activation     100949638 (ADCY4)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100949638 (ADCY4)    05163 Human cytomegalovirus infection     100949638 (ADCY4)   09165 Substance dependence    05032 Morphine addiction     100949638 (ADCY4)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     100949638 (ADCY4)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100949638 (ADCY4)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     100949638 (ADCY4) Enzymes [BR:oga01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      100949638 (ADCY4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N Motif Other DBs NCBI-GeneID:  100949638 NCBI-ProteinID:  XP_023363931 Ensembl:  ENSOGAG00000006079 LinkDB All DBs Position Unknown AA seq 1077 aa AA seqDB search MARLFSPRPPPSEDLFYETYYSLSQQYPLLLLLLVIVLCTLVALLVVAWASGRELAADPS FLTTVLCALGAFSLLLGLASREQRLQRWTRPLSGLVWAALLSLGHGFLFTGGVVSAWDQV SFFLFVIFTVYAMLPLGMRDAVAAGLTSSLSHLLVLGLYLGPQPDLRPALLPQLAANAVL FLCGNVVGAYHKALMECALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAREMK AEIMARLQAGQGSRPESTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNE LFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRAATG VDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHITRATLALLAG AYAVEDAGMEHRDPYLRELGEPTYLVIDPRAEEEDEKSTAGGLLSSLEGPKLRPSLLMTR YLESWGAAKPFAHLSHVDSPGSTSTPLPEKALASFSPQWSLDRGRTPRGLDDELDTGDAK FFQVIEQLNSQKQWKQSKDFNPLTLYFREKEMEKQYRLSALPAFKYYAVCAFLVFLSNFV IQMLITNRPPALVITYSITFLLFFLLLFICFSEHLTRCVLKGPKMLHWLPALSGLVATRP GLRVALGTATILLIFAMAITSLFLLPASSDCPFWTRNVSAMTFNHSWELAGSLPLISVPY SMHCCVLGFLSCSLFLHMSFELKLLLLLLWLAASCALFLHSHAWLSDCLIARLYLGLSDS RPGVLKEPKLMGAISFFIFFFTLLILARQNEYYCRLDFLWKKKLRQEREETETMENLTRL LLENVLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPEFKEFYSESDINHEGLECLR LLNEIIADFDELLSKPKFSGVEKIKTICSTYMAATGLNATSGQDSQQDGERSCSHLGTMV EFAVALGSKLDVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMEST GVLGKIQVTEETARALQSLGYTCYSRGVIKVKGKGQLCTYFLNTDLARTGPPSATLG NT seq 3234 nt NT seq  +upstreamnt  +downstreamnt atggctcgcctcttcagcccccggccaccccccagcgaagacctcttctacgagacctac tacagcctgagccagcagtacccgctgctgctactgctgctagtgatcgttctctgcacg ctggtggcgctgctcgttgtcgcctgggccagcggcagggagctggccgcagaccccagc ttcctgaccactgtgctctgtgcgctgggtgccttctccttactgttgggccttgcttcc cgggagcagcgactgcagcgctggacacgtcccctgtctggcctagtatgggctgcactg ctctcgctaggccacggtttcctgttcactgggggtgtggtgagcgcctgggatcaggtg tccttctttctctttgtcatcttcaccgtgtatgccatgctgcccttgggcatgcgggat gctgttgccgcaggtctcacctcctccctctcgcacctgctggtcctcgggctgtacctt gggcctcagccagacttacggcctgcactgctgccacagctggcagcaaatgcagtgttg ttcctatgtggaaatgtggtgggggcgtaccacaaggcgctgatggagtgcgcactgcgt gccaccttcagagaggccctcagctccctgcactcgcgccgtcggctggacaccgagaag aagcaccaggaacacctacttctctccatccttcctgcctacctggcccgagagatgaag gcagagatcatggcacggcttcaggctggacaggggtcacgaccggaaagcaccaacaac ttccacagcctctatgtcaagaggcaccagggagtaagtgtgttgtatgcggacatcgtg ggcttcacgcggctggccagtgagtgctcccctaaggagctggtgctcatgctcaacgag ctctttggcaagttcgaccagatcgccaaggaacatgaatgcatgcggatcaagatcctg ggggactgttactactgtgtctcggggctgccgctctcattgccagaccacgccatcaac tgcgtgcgcatggggctggatatgtgccgagccatcaggaaactgagggcagccactggt gtggacatcaatatgcgtgtgggtgtgcactcaggcagcgtgctctgtggagttattggg ctacagaagtggcaatatgatgtatggtcccatgatgtcaccctggccaaccatatggag gcgggcggcgtaccaggacgagtgcatatcacaagggccaccctggccttgctggcaggg gcttatgctgtggaggatgcaggcatggaacaccgagacccataccttcgggagctaggg gagccaacctacctggtcattgatcctcgggccgaggaggaggacgagaagagcactgca ggagggttgctgtcttctcttgagggccccaagctgcgcccatcactactgatgactcgc tacctagagtcctggggtgcagccaagccttttgcccacctgagccatgtagacagccct gggtccacctccacccctctcccggagaaggccctggcttccttcagcccccagtggagc ctggatcggggccgcaccccccgggggctggacgatgagctagacactggggatgccaag ttcttccaggtcatcgaacagctcaactctcagaaacagtggaagcagtcgaaggacttc aacccactgacgctgtacttcagagagaaggagatggagaaacagtatcgactgtctgca ctccctgccttcaaatactatgcagtgtgtgccttcctggtttttctctccaacttcgtc atccagatgctgataacaaacaggcccccagctctggtcatcacctacagcatcaccttc ctcctcttcttcctcctcctcttcatctgcttctcagagcacctgacgaggtgtgtcctg aaaggccccaagatgctgcattggctgcctgcactgtctggcctggtggccacacgacct ggactgcgagtagccctgggcactgccaccatcctcctcatctttgccatggccattacc agcctgttcctcttaccagcatcatcggactgccctttctggactcgcaatgtgtccgcc atgactttcaaccactcctgggagcttgctgggtccctgcctctcatcagtgtcccatac tccatgcactgctgcgtgctgggcttcctctcctgctcactcttcctgcacatgagcttc gaactgaagctgctgctgctcctgctctggctggcagcctcctgcgccctcttcctgcac tcccatgcctggctgtctgactgcctcatcgcccgcctctatctgggcctctcagactcc aggcccggagtgctgaaggagcccaaactgatgggagctatctccttcttcatcttcttc ttcaccctcctcatcctggctcggcagaatgagtattactgccgcctggactttctgtgg aagaagaagctgaggcaggagcgggaggaaacagagacaatggagaacctgactcggctg ctcctggaaaatgtgctccctgcacacgtggctccccagttcattggccagaatcggcgc aatgaggacctctaccaccagtcctatgagtgtgtttgtgtcctcttcgcctcggtccca gaattcaaggagttttactctgaatctgacatcaaccacgaggggctagagtgtttgcgg ctgctcaatgagataattgccgattttgatgagctgctctccaagcccaagttcagtgga gtggagaagatcaaaaccatctgcagcacttacatggcagccacaggcttaaatgccacc tctggacaggattcacaacaggatggtgagaggagctgcagccaccttggcaccatggtg gaatttgcagtagccctggggtctaagctggacgtcatcaacaagcactcattcaacaac tttcgccttcgtgtggggttgaaccacggaccagtagtggctggagtgattggagcccag aaaccacaatatgatatttggggcaacacagtgaacgtggccagccgcatggagagtaca ggagtccttggcaagatccaagtgactgaagagacagcccgggccctgcagtctctgggc tacacttgctacagccgaggtgtcatcaaggtcaaaggcaaaggacagctctgcacatac ttcctaaacacagacttggcacgaactggacctccctcagccaccctaggctga

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