Otolemur garnettii (small-eared galago): 100954535 Help Entry 100954535         CDS       T07855                                  Symbol SYNE1 Name (RefSeq) nesprin-1 isoform X7   KO K19326   nesprin-1 Organism oga  Otolemur garnettii (small-eared galago) Pathway oga04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:oga00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     100954535 (SYNE1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:oga03036]     100954535 (SYNE1) Chromosome and associated proteins [BR:oga03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     100954535 (SYNE1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Spectrin Spectrin_SYNE1 CH SYNE1 KASH Motif Other DBs NCBI-GeneID:  100954535 NCBI-ProteinID:  XP_003797918 Ensembl:  ENSOGAG00000012587 LinkDB All DBs Position Unknown AA seq 8796 aa AA seqDB search MATSRAASRSPRDIANVMQRLQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDG VKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALKFLEGRKIKLVNINSTDIADGRPS IVLGLVWTIILYFQIEELTSNLPQLQSLSSSASSVDSIVSSETASPPSKRKVATKMQGNA KKALLKWVQYTAGKHTGIEVKDFGRSWRSGVAFHSVIHAIRPELVDLEKVRGRSNRENLE DAFSIAETELGIPRLLDPQDVDVDKPDEKSIMTYVAQFLKHYPDIHTSVTDGQENDEYGF LSFANCIQNFKREDRLILKETKAWIEQFERDLTRAQMAEANLQDKYQSFKHFRAQYDMKR KQIEHLTQPLHKDSKLSLDQALVKQSWDRVSSRLFDWHIQLDKSLPAPLGTIGAWLYRAE VALREEITVQQVHEETANTIQRKLEQHKDLLQNLDAHKRAFHEIYRTRSVNGIPVPHDQL EDMAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRESVELLLQN YIAFIENSKFFEQYEVTYQILKQTAEMYVKADGSVEEAENVMKFMNETTAQWRNLSVEVR SVRSMLEEVLSNWDRYGSTVASLQAWLEDAEKMLNQSENAKKDFFRNLPHWIQQHTAMND AGNFLIETCDEMVSRDLKQQLLLLNGRWRELFMEVKQYARADEMDRMKKEYTDCVNTLSA FATEAHRKLSEPLEVSFMNVKLLIQDLEDIEQKVPVMDAQYKMTTKTVHLISKESPQEEA KEMFATMSRLKEQLSKVKECHSPLLYESRQLLTPLEELEKQMTSFYDSLGKINEILTVLE HEAQSSALFKQKHQELSACQESCKKTLTLIEKGSQSAQKFVTLSSVLKHFDQTKLQRQIV DIRVAFQNMVKKTGDWKKHVETNSRLMKKFEESRAELEKVLRIAQEGLEEKGDPEELLKR HTEFFSQLDQRVLNAFLKACDELTDILPEQEQPGLQEAVRKLHKQWKDLQGEAPYHLLHL KIEVEKNRFLALVEECRTELERETMLVGQEGSEKIIKEHRIFFSDKGPHHLCEKRLQLIE ELCVKLPVRDPVRDTSGTCHVALKELRAAIDSTYVTLMEDPDKWKDYASRFSELSSWISC KETQLKAIEGEAISTDNQEELTRAVAEIRNGVTKRGETLSWLKARLKILIEVSSENEAQK QGNELAKLSSSFKALMTLLSEVEKMLSNFGDHVQHKEIVKNSLEELISGSREVQEQAEKI LDTENLFEAQQLFLLHQQKTKRISAKKRELQQQMAQGQQGAGGLPGSSPGELRQLESTLD GLERSQERQERRIQVTLRKWERFETNKETVVRYLFQTGSSHERFLSFSSLESLSSELEQT KEFSKRTESIAVQAENLVKEASEISLGPKNKQLLQQQATSIKEQVQKLEATLEDDIKTME MVKTKWDHFGSNFESLSIWITEKEKELNALESSSSAMDVQISQIKVTIQEIESKISNITG LEDEAQSFAQFITTGESARIKAKLTQIRRYWEELREHAQCLEGTILGHLSQQQKFEENLR KIQQSVSEFEDKLADPIKICSSATETYKILQEHMDLCQALESLSSMVTAFSASARKVENR DSCVQEATALQQRYQGTVNRAKERQTALENLLAHWQKLEKELASFLTWLERCEAIASSPE MDISADRVKVEGELQLIQALQGEVVSQASSYSNLLQLKESLFSVASKDDVKMMKLHLEQL DERWRDLPQIISKRANFLQAAVAEHQQFDELLLSFSVWIKLFLSELQATSEISLTDHQVA LSRHKDHAAEVEGKKGELQSLQDHLAKLASLGRAEDLHLLQGKAEDCFQLFEEASQVVER RQLALAQLAEFLQTHASLSGALYQLRQTVEATSSMNKKQSDLLEKDLQGAIQDAKALEST AISLDGVLTKAQYHLKSGSSEQRTSCRAAADQLCAELARIQNLLGTKQSEADALAILKKA FQDHKEELLKNIEDIEERADKERLKEPTRQALQQRLRVFNQLEDELNSHEHELCWLKDKA KQIAQKDVAFAPEVDREINRLEVTWDDTKKLIHENQGQCCGLIDLMREYQNLKSTVSKVL ENASSVIATRTTIKDQEDLKWAFSKHETIKNEMNYKQKELDNFTSKGKQLLSELRKIHSS DFNLVKTDMETTVDKWLDFSERVEESMERLRVSLSIWDEVLLSKDEIEGWSNNSVPQLAE NVTNLNDSLRTEEFLKEFESEVKNKTLRLEELYSKVNDLKELTKNPETPPDLQFMEADLR QKLEHAKEITEVAKGTLKDFTAQRTQVEKFINDITAWLAKEEESVMNCAQTETCEGLKKV KDIQKELQSQQNSISSTQENLNGLCRKYHSAELETLGHAMTRLIKKHEAVSQLCSRTQAS LQESLENHFNESMREFQEWFSGAKAAAKESSDRTGDSKVLEAKIHDLQNILDSVSDGQSR LDVVTQEGQTLYAHLSKQIVSSIQEQITKANEEFQAFLKQCLKDKQTLQDCASELGSFED QHRKLNLWIHEMEERLNTENLGESKQHIPEKKNEVHKVEMFLGELLAARESLDKLSQRGQ LLSEEGHGAGQEGRLCSQLLTSYQNLLRMTKDKLRSCQVALQEHEALEAALQSMWSWVKA VQDRLAGAESTLGSKDALEKRLSQIQDIILMKGEGEVKLNMAIGKGEQALRSSNKEGQKV IQTQLETLKEVWADIMSSSIRAQSTLESVIRQWNDYLERKNQLEQWMESVDGKVEHPLQL QPGLKEKFSLLDHFQSILSEAEDQARALQCLTAKSRELYEKTEDESFKDAAQVELKTQFN DIVTVAKEKMRKVEEIVKDHLMYLDAVQEFTDWLHSAKEELHRWSDVSEDSSATQKKLVK IKELIDSREIGAGRLSRVESLAPEVKQNTTASGCELMHAEMQALRADWKQWEDSVFQTQS SLENLVSQMALSEQEFSGQVAQLEQALEQFGALLTTWAQQLTLLEGKNTDEEIVECWHQG QEILDALQKAEPRTEDLKSQLNELCRFSRDLSTYSGSVSGLIKEYNCLCLQASKGCQNKE QILQQRFQKALRDFQQWLVNAKITTAKCFDIPQNISEVSASLQKIQEFLSESENGQHKLN VLLSKGELLSTLLTQEKAKGIQAKVATAKEDWKNFHSNLHQKESALENLKIQMKDFEVSA EPVQDWLSKTEKVIQESSRRLYDLPAKRREQQKLQSVLEEIQCYEPQLSRLREKAQRLWE GQAASQSFRHRVSQLSSQYLALSSLTKEKVSRLDRIVAEHNQFSLGIKELQDWMTDAVHM VDSYCHPTSDKSVLESRILKLEALLSVKQEKEIQMKMILTRGESVLQNTSPKGIPAIQQQ LQSVKDTWAALSSAVIRCKSQLEGALSKWTSYQDDVRQFATWMDGVEASLNESERQCAEL REKTAALGKAKLLNEEVLSHSSLLETIEVKGAGMTEHYVTQLELQDLQERYSTIKDRAQE AVTKSEKLVRLHQEYQRDLKAFEVWLAQEQEKLDQYSALEGDAHTHESTLRDLQELQVRC AEGQALLNSALHTREDVIPSGIPQAEDRALESLRQDWQAYQHRLSETRTQFNNIVNKLRL MEQKFQQVDEWLKTVEEKVIFRTGRQSNRATKEMQLHQMKKWHEEVTTYRDEVEEVGAGT QEILDESPVSSRMGCQATQLTSRYQALFLQVLEQIKFLEEEIQSLEESELSLSSYSDWYG STHKNFKNVATKIDKVDAAMMGKKLKTLEVLLKDMENGHSLLKSAREKGERALQYLEEGE AETLRKEIHSHVEQLKGLTSTVRKEHMALEKGLHLAKEFSDKCKVLTQWIAEYKGILHSP EEPKMELYEKKAQLSKYKSLQQMVLSHEPTVKSVREKGEALLEVVEDVTLQDKIDKLQSD YQDLCHAGKEHVFSLEAKVKDHEDYNSELQEVEKWLLQMSGRLVAPNLLESSSLETITQQ LAHHKAMMEEIAGFEDRLNNLKIKGDTLIGQCAGHLQARLKQNVQAHLQGTADSYSAICN TAQRVYRSLEHELQKHVSRQDTLQQCQAWLSAVQPELESSPQPPLSRTEAVKQVKHFRAL QEQARTYLDLLCSMCDLSDASVKTTAKDIQQTEQMIEQRLAQAQNLTQGWEEIKQLKAEL WIYLQDADQQLQNMKRRHAELELNIAQNMVSQVKDFVKKLQCKQASVSAIVEKVNELTKN QESPEHKEISHLNDQWLDLCLQSNNLCVQREEDLQRTRNYHSCKNVVETFLEKFTTEWDN LARSDAESTAVHLEALKKLALALQERKQAIEDLKEQKQKMIEHLNIDDKELVKEQTSHFE QRWFQLEDLVKRKIQVSVTNLEELNVVQSRFQELMEWAEEQRPSITEALKQSPPPEMAQN LLMDHLAICSELETKQMLLKSLIKDADRVMADLGLNERQVIQKALSDAQKHVNCLSDLVG QRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDDVSKQVKTCKSAQAS LKTYQNEVTGLWAQGRELMKGITEQEKSEVLGKLQELQSVYDTVLQKCGHRLQELEKNLV SRKHFKEDFDKACHWLKQADIVTFPEINLMNESPELHAQLAKYQHILEQSPEYENLLLTL QRTGQAILPSLNEVDHSYLSEKLNALPQQFNVVVALAKDKFYKVQEAILARKEYASLIEL TAQSLNELEAQFSRMSKVPTRLITGEAQALQDGCRALLGEVLSLGEAVDELNQKKESFRS TGQPWQPDKMLHLVTLYHRLKRQTEQRIGLLEDTTSAYQEHEKMCQQLQRQLESVKGEQS KVNEETLPAEEKLKTYHSLAGSLQDSGILLKRVTVHLEDVAPHLDPSAYEKAKQQIQSWQ EELKLLTSAIGETVAECESRMVQSRDFQTEMSRSLDWLRRVKAELSGPVLLDLKLQDIQE EIRKIQIHQEEVQSSLRIMTALSNKEKEKFTKAKELISADLEHTLAELSELDGDIQEALR TRQATLIEIYSQCQRYYQVFQAANDWLEDAQEMLQLAGNGLDVESAEENLKNHMEFFSTE AQFHSNLQELQGLVASLDPLIKPTGKEDLAQKMASLQDKSQRIIQDSHAQLDLLQRCTTL WQDYQKAREEIIELMNDAEKKLSEFSLLKASSRQEAEEKLSEHKALASVVNSFHEKIVAL EEKASQVEKTGNDASKAALSRSVTTVWQRWTRLRAVAQDQEKILGDAVEEWKGFSSKVKK ATEMLDQLQGKLPGSSAEKASKAELVALLECHDTFLPELEQLQATLGVLRQQALSVLQDG GLPSPGEESPFMQEITAVQDRCLNLQEKVKNNGKLVKQELKDREIVETQINSVKHWVQET KEYLGNPTIEIDAQLEELQILLTEATSHRQNIEKLAEEQKNKYLGLYAILPSELSLQLAE VALDLKIRDQIQDKIKEVEQSKAMSQEFSQQIQKIAKDLTTILTKLKTKTDNLAQAKSDQ KVLGEELDGCNSKLMELDAAVQKFSEQNGQLGQPLARKIGKVMELHQQTIRQAENRLSKL TQAASHLEEYNEMLELILKWIEKAKILVHGNIAWNSASQLREQYILHQTLLEESEEIHSD LEAMTEKLQCLTSVYHTEKMSQQVAELGRETEELKQMIKIRLQNLHDAAKDMKKFEAELR NLQAALEQAQATLTSPEVGRLSLKEQLSHRQHLLSEMESLKPKVQAVQLCQSALRIPEDV VASLPLCHAALRLQEEASRLQHTAIQQCDIMQEAVVQYEQYEQEMKHLQQLIEGAHREIE DKPVATSNIQELQAQISRHEELAQKIKGYQEQIASLNSKCKMLTMKARHATMLLTVTEVE GLAGAGEDLDGELLPAPTAHPSVVMMTAGRCHTLLSPVTEESGEEGTSSEISSPPACRSP SPVANTDASVNQDIAYYQALSAEKLQTDAARISPSRSTSQEFYEPGLEPSATAKLGDLQR SWETLKNVISEKQRTLYEALERQQRYQDSLQSISTKMEAIELKLSESPEPDKSPESQMAE HQALMDEILMLQDEINELQSSLAEELVSESRESDPAEQLALQSTLTVLAERMSTIRMKAS GKRQLLEEKLNDQLEEQRQEQALQRYRCEADELDHWLLSTKATLDVALGPPKEPMDMEAQ LVDCQNMLVEIEQKVVVLSELSVHNENLLLEGKAHTKDEAEQLGAKLRRLKGSLLELQRA LHEKQLNIQGTAPEKEDSDADLIAAQSPGVQEWLAQARTTRTHQRQNSLQQQKELEQELA EQKSLLRSVATRGEEILTQHSAAELTGGAGEKPDVLSQELGMEGEKSSAEDQMRMKWESL HQEFSTKQKLLQNVLEQEQEQVLYSRPSRLLSGVPLYKGDGQTQDKSAVTSLLDGLNQAL EEEVSSQGGGSKRQSIHLEQKLYDGVSATSTWLDDVEERLFVATALLPEEAETCLFNQET LAKDIKEMSEEMDKNKNLFSQAFPENGDNRNVIEDTLGCLVGRLSLLDSVVNQRCCQMKE RLQQILSFQNDLKVLFTSLADNKYIILQKLANVFEQPVAEQIEAIQQAEEGLKELDAGII ELKRRGDKLQIEQPSVQELSKLQDMYDELMMIIGSRRSGLNQNLTLKSQYERALQDLADL LETGQEKMAGDQKTIVSSKEEIQQLLDKHKEYFQGLESHMILTETLFRKIVSFAVPKETQ FHTELMAQASTVLKQAHRRGVELEYILETWSRLDEDQQELSRQLEVVESSIPSVGLVEEN EDRLIDRITLYQHLKSSLSEYQPKLYQVLDDGKRLLMSISCSELESQLNQLGEHWLNNTN KVSKELHRLETILKHWTRYQSESADLIHWLQSAREKLEFWTQQSVTVPQELETVRDHLNA FLEFSKEVDAKSSLKSSVLSTGNQLLRLKKVDTATLRAELSRIDGQWTDLLTNIPAVQEK LHQLQMDKLPSRHAISEVMSWISLMENVIQKDEDNIKNAIGGKALHEYLQKYKGFKIDIN CKQLTVDFVNQSVLQISSQDVESKRSDKTDFAEQLGAMNKSWQILQGLVSEKIQLLEGLL ESWSEYENNVQCLKTWCETQEMKVKQQQCVGDQASVQNALKDCQDLEDLIKAKEKEVEKI EQNGLALIQNKKEDVCGTVVSTLQELSQTWANLDHMVGQLKLQLKTVLEHWSSHKAAFDE INSFLMEARYSLSRFRLLTGSLEAVQVQVDNLQSLQDDLENQEKSLQKFGSVTSQLLKEC HPPVTETLTNTLKEANMRWNNLLEEIAEQLHSSKALLQLWQRYKDYSKQCSATVQQQEDR TNELLKAAASKDIPDEEVATWIQDCNDLLKGLGTVKDSLYVLRELGEQLKQQVDTSAASA IQSDQLSLSQHLQALEQALCKQQAVLQAGVLDYETFAKSLEALEAWIVEAEDILQGQDPS HSSDLSTIQERMEELKGQMLKFSSMAPDLDRLNELGYRLPLNDKEIKRMQNLNRHWSLIS SQTTERFSKLQSFLLQHQTFLEKCETWMEFLVQTEQKLAVEISGNYQHLLEQQRAHELFQ AEMFSRQQILHSIIVDGQRLLEQGQVDDRDEFNLKLTLLSNQWQGVIRRAQQRRGIIDSQ IRQWQRYREMAEKLRKWLVEVSYLPVSGLGSVPIPLQQARTLFDEVQFKEKVFLRQQGSY ILTVEAGKQLLLSADGGAEAALQVELTEIQEKWKSASMSLEEQKKKLAFLLKDWEKCEKG IADSLEKLRTFKKKLSQPLPDHHDELHAEQTRCKELENAVGSWTDDLSQLTLLKDTLSAY ISADDISILNERIELLQRQWEELCHQLSLRRQQVSERLNEWAVFSEKNKELCEWLTQMES KVSQNGEILIEEMMEKLRKDYQEEIAVAQENKIQLQQMGERLARASHESKASEIEYKLGK VNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTWLTHIESELAKPIVYDSCNSEE IQRKLSEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQATRNLDRRWR NICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKISERTAALPRSSGVIYIVAKEELKT FEAFQRQVHECLTQLELINKQYRRLARENRTDSAGSLKQMVHEGNQRWDNLQKRVTSILR RLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNHN KIEQIIAQGEQLIEKSEPLDAAVIEEELDELRRYCQEVFGRVERYHKKLIRLPLPDDEHD LSDRELDLEDSAALSDLHWHDRSADSMLSPQPSSNPSLSLAQPLRSERSGRDTPASVDSI PLEWDHDYDLSRDLESAVSRTLPSEDEEGQEDKDFYLRGAVGLAGDHSALESQIRQLGKA LDDSRFHMQQTENIIRSKTPTGPELDASYKGYMKLLGECSGSIDSVRRLEHKLKEEEESL PGFVNLHSTEMQTAGVIDRWELIQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEE ELERLRRLELSTDIQAIELQIKKLKELQKAVDHRKAIILSINLCSSEFTQADSEGSRELQ DRLSQMNGRWDRVCCLLEAWRDLLQDALMQCQDFHEMSHGLLLMLENIDRRKNEIVPVDP NLDAEILQDHHKQLIQIRRELLESQLKVTSLQDMSCQLLVNAEGTDCLEAKEKVHVIGNR LKLLLKEVSRHIKELEKLLDMSSSQQDLSSWSSADELDTSGSVSPASGRSTPNRQKTPRG KCSLSQPGPSVSSPQSRCTKGGSDSSLSEPRPARSGRAFLYRVLRAALPLQLLLLLLIGL ACLVPMSEEDYSCALSNNFARSFHPMLRYTNGPPPL NT seq 26391 nt NT seq  +upstreamnt  +downstreamnt atggcaacctccagagcggcctcacggtcccctcgggacatcgccaatgtgatgcagagg ctgcaagatgagcaagagatagtacaaaaacgcactttcacaaaatggatcaactctcac ctggccaagcggaaacccccaatggtcgtggatgatctttttgaagacatgaaagatggt gttaagctgcttgcgctcctggaggtcctatctgggcagaaactgccttgtgaacaagga cgccggatgaagcgaatccacgctgtggctaacatcggcacagcgctgaagttccttgaa ggaagaaagattaaattagtcaacattaactccacggatatagctgatggccgaccctca atagttcttggattggtgtggaccattattctgtatttccagatagaagagctgaccagc aacctgccccagctccagtctctgtccagcagcgcatcctccgtggacagcatagtgagc tctgagacagccagcccgcccagtaaacggaaggtggccaccaagatgcaaggaaatgct aagaaggctttattaaaatgggttcagtacacagcgggcaagcacacgggaatagaagtc aaagactttgggaggagttggagaagcggggttgcctttcattcagtgatccacgccatt cgacctgaactagtggacctggaaaaagtgagaggcagatctaacagagagaatctggag gacgctttctccatcgccgaaacagaactggggatcccaagactgctggacccccaagat gttgatgtagataaaccagatgagaagtctattatgacatatgtagcccagtttctgaaa cattatcctgacatccacacttcagtcaccgatgggcaagagaacgatgaatatggtttc ctatctttcgcaaattgtatccaaaatttcaagagagaagacaggctaattttgaaggaa acaaaagcttggatagaacaattcgagagagatttgacaagggcacaaatggcagaagca aatttgcaggataaatatcagtcattcaagcacttcagagcccaatatgatatgaaaagg aaacagattgaacatttaacacaaccattacataaagacagtaaattgtcccttgaccaa gcattggtaaaacagtcctgggacagagtgtcctccaggctctttgactggcatattcag ctcgataaatctctccctgcacctctgggcaccataggtgcctggctgtacagggcagag gtggccctgagagaggagataaccgtccagcaggtccacgaggaaacagcaaacacaata cagcggaagctggagcagcataaggatctgcttcaaaacctagatgcccacaaaagagca tttcatgaaatctaccggaccaggtctgttaacggaatcccggtgccacatgatcaatta gaggacatggctgagaggtttcattttgtttcctccacatcagagctacatctaatgaaa atggaatttctagaattaaagtatcgcctgctctcactgctggttcttgcagagtcaaag ctcaagtcttggatcattaagtacgggaggagagagtcagtggagctgcttctgcaaaac tacatcgcttttatcgaaaatagcaagttctttgagcagtatgaagtgacataccagatc ttgaaacagactgctgagatgtacgtcaaagcagatggttcagtggaggaagctgagaat gtgatgaaattcatgaatgaaaccactgctcagtggagaaatctctcggtggaagtgagg agcgtgcggagtatgttggaggaggtgctctccaactgggaccgctatggcagtactgtg gctagtctccaagcctggctagaggatgctgaaaagatgctaaatcagtctgaaaatgcc aaaaaggatttttttcgaaatctccctcattggattcagcaacacactgccatgaacgat gctggcaatttcctaattgaaacgtgtgatgagatggtttcccgggaccttaagcagcag ttactgctgctgaacgggcgctggagggagctgtttatggaggtcaagcaatacgctcga gctgatgagatggacagaatgaagaaagaatacacagactgtgtgaataccctgtctgct tttgcaacagaagcccataggaaactttcggaacccttagaagtctctttcatgaatgtc aagttgttaatccaagacttggaggatattgagcagaaggtgcctgtgatggatgcccag tacaagatgactacaaagacagtgcacctcatttccaaagagagcccccaagaagaagcg aaggaaatgtttgcaaccatgtcgagactcaaagagcaactttccaaggtcaaagaatgt cactccccactcctttatgagtctcggcagctgttgactccgttggaggaactagaaaag caaatgacatccttttatgactcacttgggaaaatcaatgaaattctaacagttcttgag cacgaggcacaatctagtgctctttttaaacaaaaacatcaggaactgtcagcctgtcaa gaaagctgtaagaaaaccttgacactgattgagaaaggcagtcaaagcgctcagaagttt gtgaccctgagcagtgtgttaaagcattttgatcagacaaagctacaacgacagattgta gatattcgtgttgctttccagaatatggtaaagaaaactggagattggaagaagcatgtt gaaactaacagtcggttgatgaagaaatttgaggagtctcgagcagagttggagaaggtg ctgcggattgctcaggagggcctggaggaaaagggggacccggaggagctcctgaagaga cacactgagttcttcagtcagctggatcagagggtgctcaatgccttcctgaaggcttgt gatgaacttaccgacatcctccctgagcaggagcagccaggtctgcaggaagctgtgaga aaactccacaaacaatggaaggatcttcaaggagaagctccttatcacttgcttcatctg aagatcgaggtggagaagaacagattcttagccttggtagaagaatgcagaactgagctg gagcgagagaccatgctggtgggccaggaaggcagcgaaaagatcattaaagagcacagg attttcttcagtgacaaaggtcctcaccacctctgtgagaaaaggttacagctcattgag gaactgtgtgtgaaactcccagtccgggacccagtgagggacacatcaggaacctgtcat gtggctctcaaagagcttagagctgccattgacagcacctatgtgacactcatggaagac ccagacaagtggaaggactatgctagcagattttcagaactctcgtcttggatatcttgt aaggagacacagttgaaggctatcgagggtgaggccatcagcacggacaaccaggaagag ctcacacgtgctgttgcagagatcagaaatggtgttaccaaaagaggtgagactctcagc tggctaaaagccaggctgaaaattttgattgaagtttcttctgagaacgaagcccaaaag caagggaatgagctggcaaaactctccagctctttcaaggctctgatgaccctcctgtca gaggttgaaaagatgttaagcaactttggggatcatgtccagcacaaagaaatagtcaaa aattcccttgaagaattaatttctggctctagagaagttcaggagcaagctgagaaaatc ttggacactgaaaatctgtttgaagcacagcagttatttctccttcaccagcaaaagaca aagcggatctcagcaaagaagagagaattgcagcagcagatggctcaggggcagcaggga gcaggggggctgccagggagcagccccggggagctacggcagctggagagcaccctggac ggcctggagcgcagccaggagcgccaggagcgccgcatccaggtcacattaagaaaatgg gagcggtttgaaacaaacaaagaaacagttgtcagatacctttttcagacaggttccagc catgaacgcttcttgagttttagcagtttggaaagtttgtcttcagagttggaacagaca aaggagttttctaaacggacagaaagcattgcagtccaggctgagaatcttgtaaaggaa gcttcggagatttcccttgggcccaaaaataaacagctgctgcaacagcaggccacgtca atcaaagagcaagtccaaaaattagaagccacgcttgaagacgatattaaaaccatggaa atggtgaaaaccaagtgggatcattttggcagtaattttgagagtctgtccatctggata actgaaaaagaaaaggagctcaatgccttggaatcatcgtcatctgccatggatgtgcaa atcagccaaattaaggtcacaattcaagaaatagaaagtaagatcagcaacattacagga ttagaagacgaagctcagtcgtttgctcagtttattaccactggagaatccgctcgaatc 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cagggcaaggcagaggactgcttccagctgtttgaggaggccagccaggtcgtggagagg aggcagcttgccctggcccagttggcagaattcctgcagacccatgcctctctgtccggg gctctctaccaactgaggcaaacggtggaagcaaccagcagcatgaataagaaacagtct gatttgctagaaaaggacctccaaggtgctattcaagatgccaaagcattagaatcgacc gccatcagtctcgatggtgttctcaccaaagcccagtaccacctgaaaagtgggagctct gagcagaggacttcctgccgggctgcagccgatcagctctgtgcagagttagcgaggatc cagaacctgctgggaaccaagcagagcgaggcagatgccctagcgatattgaaaaaggcg ttccaagaccacaaagaggagttgctaaaaaacatcgaggacattgaagaaagggctgac aaggagagattaaaagaaccgacccgccaagctctccagcagaggttgcgagtatttaat cagctagaagatgaattaaattctcatgagcatgaattatgctggttgaaagacaaagct aaacaaattgcccagaaagatgtagctttcgcacctgaagttgacagggagataaaccgc ttagaggttacctgggatgataccaaaaaactaattcatgaaaaccagggtcaatgctgc gggcttattgatttaatgagagaatatcagaatttgaagtcaactgtgtcaaaagtccta gaaaacgccagcagtgtgattgcaaccagaactactataaaggatcaggaggatcttaaa tgggctttttcgaagcatgaaactatcaagaatgaaatgaattataaacagaaagagctg gacaatttcacgagtaaaggaaaacagttgttatctgagctgagaaaaattcacagtagt 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gtgctgctgtctaaaggtgaacttctgagtactctgctgacccaggagaaagctaaaggg atccaggccaaggttgcaactgcaaaagaagattggaaaaattttcactcaaatctccac caaaaagaatccgccctagagaatctaaagattcaaatgaaggacttcgaagtcagcgct gagcccgtgcaggactggctgagtaagacggagaaggtgatccaggagagcagccgtcgc ctctacgacctgccagccaagaggagagagcagcagaagctccagtctgtccttgaggaa atacagtgctacgagcctcagctcagcaggctgagagagaaagctcagcggctgtgggaa ggacaagctgccagccagagctttaggcacagagtgtcgcagctgtcttctcagtaccta gcgctgagcagtttgaccaaggagaaagtgtcaagattggacagaattgttgccgaacac aatcagttctctctcggcattaaagaattacaagactggatgacggatgctgttcacatg gtggactcttactgccacccgacctcggacaagagtgtcctggagagcaggatactcaag cttgaggctctattatcagtgaagcaggaaaaagagatccagatgaaaatgatactgacc aggggagaatctgtccttcagaatacctctccaaaaggtattcctgccatccagcagcag ctgcagagtgtgaaggacacgtgggctgccctttcttctgcagtgattcggtgtaagagt caactcgaaggcgccctttctaaatggacaagttatcaggatgatgtgcgacagtttgcc acttggatggacggcgtggaagccagcttaaatgagtctgagaggcagtgtgcggagctg cgggagaagacagctgctctcgggaaagccaagttattaaatgaagaagtgctgagtcac 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caggagcaagccaggacctacttagatctcctttgctccatgtgtgatttgtcagatgct tccgtgaaaaccacagcaaaagacatccaacaaacagagcaaatgattgaacaaaggctt gcgcaggcgcagaacttaactcaaggctgggaggagatcaagcagctgaaggcggagctg tggatttaccttcaggatgccgaccagcaactccagaacatgaagaggaggcacgcggaa ctggagctgaatattgctcagaacatggtttcccaagtaaaggactttgtcaagaaacta cagtgcaaacaggcatcagtgagtgctattgtggagaaggtgaacgagttaactaagaac caggagtctcctgaacacaaggaaataagtcatctgaatgatcagtggctagatctgtgc cttcagtccaacaacctgtgcgtgcaaagggaagaggatcttcagagaacaagaaattac cattcctgcaagaacgtcgttgaaacattcttagaaaaatttactacagaatgggataac ttggccagatctgatgcagagagtacagctgtccacctggaagctttgaaaaagttagca ttggccttgcaggagagaaagcaagctattgaagacctgaaggaacagaagcagaaaatg atagagcatctaaatatagatgacaaggaattggtcaaagagcagacaagtcacttcgag caacgttggtttcagcttgaggaccttgttaaaaggaaaatccaagtgtcagtcaccaac ttggaggagttaaatgtggtgcagtccagattccaggagctgatggagtgggcagaagag cagcggcccagcatcaccgaggctcttaagcagagcccccctcctgagatggctcagaac cttctcatggatcacctggccatttgcagtgagctggagaccaagcagatgctcctgaag tcactcataaaggatgccgacagggtgatggctgaccttggcctcaatgagcgccaggta atccagaaggcactctcagatgcgcagaagcacgtgaactgtctcagtgacttagtgggc cagcgaaggaagtacttgaacaaggccttgtctgagaaaacccagtttctcatggcagtg ttccaggcgaccagccaaattcagcaacacgagcgaaagataatgttccgtgaacacatc tgcctgttaccagacgatgtgagcaagcaggttaaaacgtgcaagagtgcacaagccagc ctcaagacgtaccagaacgaagtgactggactctgggcccagggtcgggaattaatgaaa ggaatcacagagcaggaaaagagcgaagtgctaggtaagcttcaggaactgcagagtgtc tacgacactgttttacaaaagtgtggtcatcgtttgcaagaactggagaaaaatttagtt tctaggaagcactttaaggaagattttgataaagcttgtcattggctaaaacaagcagat attgttacctttcctgaaatcaacctaatgaatgagagccccgagcttcatgcacagcta gccaaataccaacacattcttgaacaatctccagagtatgaaaatcttctacttacgttg cagagaactggacaggccatattgccctcgctgaatgaagtcgatcattcctacctcagt gaaaagctaaatgctttgccccagcagtttaatgtcgttgttgccttagccaaagataag ttttataaagtccaggaagcaattcttgctcgaaaagaatacgcttccttgatcgagttg acagcccagtcgctgaatgaactcgaagcccagttctccaggatgagcaaagtccccacc cgtctgatcacaggcgaggctcaggctcttcaggatggttgcagagcccttctgggggag 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aagccgaaggtgcaggctgtgcagctgtgccagagcgccctccggatccccgaggatgtg gtggccagcttgcccctgtgccatgctgccctgcgcctgcaggaggaggccagccggctg cagcacacggccatccagcagtgtgacatcatgcaggaggctgtggtgcagtatgaacaa tatgagcaagaaatgaagcatctccagcaactgatagaaggagcccacagggaaattgag gataaacccgtggccaccagtaacatccaggagctgcaagcacagatttctcggcacgag gagctggctcagaaaatcaagggctaccaggagcagatcgcctccttgaattccaagtgc aagatgctgacgatgaaagccaggcacgccaccatgctgctgacggtgaccgaggtggag gggctggcgggagccggcgaggacctggatggagagctcctccccgcgcctacggcccac ccctctgtggtcatgatgactgcagggcgctgtcacacattgctgtcacctgtcactgag gagtctggggaggagggaaccagcagtgagatttcttctccacctgcctgtcgctctccc tcacctgtggctaatacagatgcttctgttaaccaggacattgcatattaccaagccttg tcggctgagaagttgcagaccgatgctgcgaggatttcccccagcaggtcgacatcccag gagttctatgagccaggactggagccatctgctactgctaaactgggcgatttgcagcgt tcgtgggaaaccttgaagaatgtgatcagtgagaagcaacgcacgctctatgaagctttg gaacgccagcagaggtaccaggactcactccagtccatctccaccaagatggaggccata gagctgaaactcagcgagagtcctgagcccgacaagagtccagaaagccagatggctgaa catcaggcactgatggatgagattctcatgctccaagatgaaatcaacgagctccagtcc tctctcgcagaagagctggtgtctgagtctcgcgagtcggaccccgcggagcagctagcc ttgcagtccacactcacggtcttggctgagcgaatgtccaccatcaggatgaaagcctca gggaaacggcagctgttggaggagaagttaaatgatcagctggaggagcagagacaggaa caagctctgcagaggtatcgctgtgaagctgacgagctggaccactggctcttgagtacc aaggccactctggatgttgcactgggtccacccaaggagcccatggacatggaggcccag cttgtggactgccagaacatgctagtggagatcgagcagaaggtggtggtcttgtcggag ctctcagtccacaacgagaacctgctgctggagggcaaggctcacaccaaggacgaggct gagcagctgggggcaaagctgagaaggctcaaggggagcctgctggagctgcagcgggcc ctgcatgaaaaacagctcaacatccagggaacagcgccagagaaagaggacagcgatgct gacctaatagccgctcagagccctggcgtccaggaatggttggcccaagctcgcaccacg cggacccaccagcggcagaacagtctccagcaacaaaaagagttggaacaggaattggcc gagcagaagagcctcctccgctcagtcgccactcgaggagaggagattctaacccagcat tcagctgcagagctcaccggtggtgctggcgaaaaacctgatgtgttgtcccaggagttg ggaatggaaggggagaagtcatctgctgaagaccagatgaggatgaaatgggaaagcctt catcaagaatttagtaccaagcagaaacttctacagaatgttctggaacaggaacaagaa caagtgctttacagcaggccaagtcgactcctgtctggtgtgccgctgtacaaaggggac gggcagacccaggacaaatctgcagttacgtctctgctggacggcctgaaccaggccctt gaggaggaggtttcatcccagggaggaggatcaaagaggcagagtatacacctggaacag aagttatatgacggtgtctcagcgacctccacctggctggacgatgttgaagaacgttta tttgtggccacagcacttttaccagaagaagcagaaacatgtctcttcaaccaagaaact cttgccaaagacattaaggaaatgtctgaagaaatggataagaacaagaacttgttttcc caagcctttccagagaacggcgataatcggaatgttattgaagataccctgggctgtctc gtgggcaggctgtctctgctagactcagtggtgaaccaacgctgttgtcagatgaaggaa agacttcagcaaatactcagtttccagaatgatctgaaggtgctgtttacgtcactggcc gacaacaaatacatcattctgcagaaactggcaaatgtgtttgaacagcctgtagcagaa caaatagaggcaatacagcaggctgaagaggggctcaaggaattggacgcagggattatt gaattaaaacggcgtggtgacaagttacagatcgagcagccttctgtgcaagaactctcc aaactccaggacatgtatgatgagctgatgatgatcattggctcccgacggagtggtctg aaccagaacctgacactcaagagtcagtatgaacgggccctgcaggatctggctgacctg ctagaaactggtcaggagaagatggcaggagaccagaaaaccatcgtgtcttccaaagag gaaatccaacaactacttgacaaacataaggaatacttccagggcctggaatctcacatg atcttgactgaaacactcttccggaagatcgtcagctttgcagtccccaaggaaacccag ttccacacagaactgatggctcaggcttccacggtgctgaaacaggctcaccggaggggc gtggagctggagtacattctggagacgtggtcccgactggacgaggaccagcaggagctc agcagacagctggaggttgtagaaagcagcatcccaagtgtgggtctggtggaggagaat gaggaccggctcattgatcgcatcacactctaccagcacttaaaatctagcctcagtgaa taccagcccaaattatatcaggttttagatgatggcaaacgacttctgatgtctattagc tgctcggaactagaaagccaactaaatcagcttggagaacactggctaaataacaccaac aaagtgtctaaggaacttcacagattggagacaatactgaagcactggaccaggtatcaa agtgaatctgcagatctaattcactggttacagtctgcaagagaaaagctagaattttgg actcagcaatctgtgacagtccctcaagagctggaaacagtccgtgatcatctaaatgct ttcctggagttttctaaagaagtagatgccaaatcttccctgaagtcatctgttctgagc actggaaatcagcttcttcggttaaagaaggtcgacacagccacactgcgcgctgagctg tcgcgcatcgatggccaatggacagacctgctgaccaatattccagccgtccaggagaag ctccaccagctccagatggataagctgccttcccgccatgccatttctgaagtcatgagc tggatttctctgatggaaaacgttattcaaaaggatgaagataacataaaaaatgccata ggtggcaaagcacttcatgaataccttcagaaatacaagggttttaagatagacattaac tgtaaacagctgactgttgattttgtgaaccaatcagtgttacaaatcagcagtcaggat gtggaaagtaaacgcagcgacaagacggattttgctgagcaacttggagcaatgaataaa agttggcaaatcttgcaaggtctagtaagtgagaagatccagcttttggaaggcttactg gaatcttggtcagaatatgaaaacaatgtacaatgtctgaaaacttggtgtgaaactcag gaaatgaaagtgaaacagcagcagtgtgtgggagaccaggcctctgttcagaatgcgctg aaggactgccaggatctggaagatttgattaaagcaaaagaaaaagaagtcgagaaaatt gaacagaatggacttgctttgattcagaacaagaaggaagacgtgtgtggcacagtcgtg agcacacttcaagaactcagccaaacctgggcgaatttagaccacatggttgggcaatta aagctgcagctgaagacggtgcttgagcactggagcagccacaaagcagcctttgatgag atcaacagtttcctcatggaggcccggtactctctttcccgattccgtctgctgactggc tccttagaggctgtgcaagttcaggtagacaatcttcagagtcttcaagatgatctagaa aatcaggaaaagagcttacagaaatttggttcagtcaccagccagctgttaaaagagtgt cacccacctgtgacagaaactctcaccaatacactgaaagaggccaatatgagatggaac aacttgctggaagagatcgctgagcagctgcactccagcaaggccctactccagctctgg cagagatacaaggactactccaaacagtgctcggccacggtgcagcagcaggaggatcga accaatgagctgctgaaggcagccgctagcaaggacatccccgacgaggaagtcgctacg tggattcaggattgcaatgacctcctcaagggactggggacagtgaaggattccctttat gttctccgtgagctgggagagcaactcaagcaacaagtggatacttcagctgcctcagcc attcaatctgatcagctgtctttgagtcaacacttgcaggccctagagcaggctctttgc aagcagcaggctgtgttgcaggctggagttcttgactatgaaacctttgccaagagtttg gaagctttggaggcctggatagtggaagctgaggacatactccaaggacaggaccctagc cactcatctgacctctccaccatccaggaaaggatggaagagcttaagggacagatgtta aaattcagcagcatggctccagatttagaccgtctaaatgagctcgggtataggttaccc ctgaacgataaggaaatcaaaaggatgcagaatctgaaccgtcactggtctctgatctcc tcccagactacagaaagattcagtaagttgcagtcatttttgctacaacatcaaactttc ttggaaaaatgtgaaacatggatggaattcctggttcaaacggaacaaaagttagcagta gagatttcaggcaattaccagcatcttttggaacaacagagagcacatgagttatttcaa gctgagatgttcagtcgtcagcagatcttgcactcgatcattgttgatggacagcgtctt ctagaacaaggtcaagttgatgacagggatgagttcaacctgaaattgacgctcctcagt aatcagtggcagggagtgatccgccgggcccagcagaggcgggggatcattgacagccag atccgccagtggcagcgctacagggagatggcagaaaagcttcgcaagtggctggttgag gtgtcctacctccccgtgagtggtctgggaagcgttcctataccactgcagcaggcaagg accctcttcgatgaagtgcagttcaaagaaaaagtgtttctgcgacagcaaggcagctat atcctgacggtggaggctggcaagcaactcctgctctccgcggatggtggagccgaggct gccttgcaggtcgaactcactgaaatccaagagaaatggaaatcggccagcatgagtctg gaggaacagaagaaaaagctggctttcttgttgaaagactgggaaaaatgtgagaaagga atagctgattctctagagaaactacggactttcaaaaagaagctttctcagcctctgcca gatcaccacgacgagctccacgcagagcaaacgcggtgcaaggaattagaaaatgcagtt gggagctggacagatgacttgtcacagctgacgctgctgaaggacaccctctctgcgtac atcagcgctgacgacatctctatccttaatgaacgcatagaacttctgcaaaggcagtgg gaagaactgtgccaccagctctccttgaggcgccagcaagtaagtgaaagattgaatgag tgggcagtcttcagtgaaaagaacaaggagctttgtgaatggttgactcaaatggaaagc aaagtgtcccaaaacggagaaattctcattgaggaaatgatggaaaagctcaggaaggat taccaagaagaaattgctgttgcccaagagaacaaaatacagctccagcaaatgggagag cgacttgccagagccagccatgaaagcaaagcatccgagattgaatacaagctcgggaag gtcaatgaccggtggcagcatctcctggacctcattgcagccagggtgaagaagctgaag gagaccctcgtggccgtgcagcagctcgataagaacatgagcagcctgaggacgtggctc actcacatcgagtcggagctggccaagccaatagtctatgactcctgcaactcagaggag atacagagaaagctcagtgagcagcaggagctccagagagacatagagaagcacagcacg ggcgtcgcctctgtgctcaacctctgtgaagtcctcctgcatgactgtgacgcttgtgcc actgacgccgagtgtgactccatccagcaggccacgagaaacctggaccggcggtggaga aacatctgtgctatgtccatggaaaggaggctcaaaattgaagagacttggcgactgtgg cagaagtttctggatgactattctcgttttgaagattggctgaagatttcagaaaggaca gctgctctccccaggtcttccggggtgatctacatagttgccaaggaagaactaaagaca tttgaggcttttcagcgacaggtccacgagtgcctgacgcagctggagctgatcaacaag cagtaccgccgcctggccagagagaatcgcaccgactcggccggtagcctgaaacagatg gttcacgaaggcaaccagagatgggacaacttgcagaagcgtgtcacctccatcttgcgc agactcaagcattttattggccagcgtgaggagtttgagactgcacgggacagcattctg gtctggctaacagagatggatctgcagctcactaatattgaacacttttctgagtgtgat gttcaagctaaaatcaagcaactcaaggccttccagcaggagatttctctgaaccacaat aagatcgagcagataatcgcccagggagagcagctgatagagaagagcgagcccctggac gcggcggtgatcgaggaggaactggacgagctccgccgctactgccaggaggtcttcggg cgcgtggagagataccacaagaaactgatccgcctgcccctcccagatgatgagcacgac ctctcggacagggagctggatctggaagactccgcagctctctcggacttgcactggcac gaccgctctgcagacagcatgctgtccccgcagccttcctctaacccctccctgtcactt gcccagcccctgcggagtgagcggtccgggcgagacaccccggccagtgtggactccatc cccctggagtgggatcacgactatgacctcagtcgggacctggagtctgcagtgtccagg accctcccctctgaggatgaagagggtcaggaggacaaagatttctacctcaggggtgct gttggcttagcaggggaccacagcgccttagagtcacagatccgacaactgggcaaagcc ttggatgacagccgattccacatgcagcaaaccgaaaatatcatccggagcaaaactccc acggggccagagctagacgccagctacaaaggttacatgaaactcctcggggaatgcagt ggcagtatagactcggtgaggagattggagcacaagctgaaggaggaggaagagagcctt cccggctttgttaacctccacagcaccgagatgcaaacagctggtgtgattgaccggtgg gagcttatccaggcccaggcgctgagcaaggagctgaggatgaagcagaacctccagaag tggcagcagttcaactctgacctcaacagcatctgggcctggctgggggacacggaggag gagctggaacggctccggcgcctggagctcagcaccgacatccaggccattgagctccaa atcaagaagctcaaggagctccagaaagctgtggatcaccgcaaagccatcatcctctcc atcaacctctgcagctccgagttcacgcaggctgacagtgagggcagccgggagctgcag gatcgcttgtcccagatgaacgggcgctgggaccgggtgtgctgcctgctggaggcgtgg cgggacctgctgcaggatgcactgatgcagtgccaggatttccacgaaatgagtcatggt ttgcttctcatgctggagaacatcgacaggaggaaaaacgaaatcgtccctgttgatccc aaccttgatgcagagattcttcaggaccatcacaaacagcttatacaaataaggcgtgaa ctgttggagtcccagctcaaagtgacctcattgcaagatatgtcttgtcaacttctggtg aatgctgaaggcacagactgtttagaagccaaagagaaagtccatgttattggaaatcgg ctcaagcttctgttgaaggaggtcagtcgtcatatcaaggaactggagaagttattagac atgtcaagcagtcagcaggatttgtcttcctggtcttctgctgatgagctagacacctcg ggatccgtgagccctgcatcgggaagaagcaccccaaacaggcagaaaacgccacgaggc aagtgtagtctctcacagcctggaccctctgtcagcagtccacagagcaggtgcacaaaa ggtggctccgattcctccctttctgagcctcgcccagctcggtctggccgagccttcctg taccgggtcctccgagcggctcttcccctccagcttctcctgctgctcctcattgggctc gcctgcctcgtgccaatgtcggaggaggactacagctgtgccctctccaacaactttgcc cggtcattccaccccatgctcagatacacaaacggccctcccccgctctga

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