Otolemur garnettii (small-eared galago): 100954677
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Entry
100954677 CDS
T07855
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
oga
Otolemur garnettii (small-eared galago)
Pathway
oga00790
Folate biosynthesis
oga01100
Metabolic pathways
oga01240
Biosynthesis of cofactors
oga01523
Antifolate resistance
oga04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
oga00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
100954677 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
100954677 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
100954677 (FPGS)
Enzymes [BR:
oga01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
100954677 (FPGS)
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Ortholog
Paralog
GFIT
Motif
Pfam:
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
100954677
NCBI-ProteinID:
XP_003785375
Ensembl:
ENSOGAG00000024954
UniProt:
H0XYQ7
LinkDB
All DBs
Position
Unknown
AA seq
587 aa
AA seq
DB search
MSQAGSHLRAALSLAAVSARGVKTRGSVSRRLSAWPVPQEPSMEYQDAVRMLNTLQTNAG
YLEQVKRQRGDPQTQLEAMEQYLARSGLQVEDLDQLNIIHVTGTKGKGSTCAFTECILRS
YGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYHQLEETKDGSCVSMPPYFRF
LTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTSLLGDTMEKIA
WQKGGIFKQGVPAFTVLQPEGPLAVLRDRAQQISCPLYLCPPLEALEEGGPPLTLGLEGE
HQRTNAALALQLAHCWLQQQDHQRTGDLKVSRPSLPWQLPLAPTFQLTSHMRLGLRNTEW
LGRTQVLRRGPVTWYLDGAHTSSSIQACVRWFRQALQGGERQSCGPEVRVLLFNSTGDRD
SAALLKLLQPCQFDYAVFCPNLTEVSSPGSADQQNFTVTLDQVILRCLEHQQHWNHLDEE
QASPDLWSTPALEPGGPAPLLLAPHPPHSCSSSSLVFSCISHALQWISQGRDPVFQPPSS
PRGLLAHPVAGSGASVLREAAAIHVLVTGSLHLVGGVLKLLEPSLSQ
NT seq
1764 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcaggcggggagccacctgcgtgcggctctgtccctggcagcggtttctgcgcgc
ggtgtaaagacccgtggctcagtgagccggcggttgagcgcgtggccggtgccgcaggag
cctagcatggagtatcaggatgctgtgcgcatgctcaataccctgcagaccaacgctggc
tacctggagcaggtgaagcgccagcggggcgacccccagacacagcttgaagccatggag
cagtatctggcacggagtgggttgcaggtggaggacttggaccagctgaacatcatccat
gtcactgggactaaggggaagggctccacctgtgccttcactgaatgcatcctccgaagc
tatggcttgaagacgggattctttagctctccccacctggtgcaggtgcgtgagcggatc
cgcatcaacgggcagcccatcagtcccgagctcttcaccaagtacttctggcgtctctac
caccagctggaggagaccaaggacggcagctgtgtctccatgcccccctacttccgcttc
ctcacactcatggccttccacgtcttcctccaagaaaaggtagacctggcagtggtggaa
gtgggcattggtggggcttatgactgcaccaacatcatcaggaagcctgtggtgtgtgga
gtctcctctcttggcatcgaccacaccagccttctgggggacacaatggagaagattgca
tggcagaaagggggaatctttaagcaaggtgtccccgcttttactgtactccagcctgaa
ggtcccctggcagtgctgagggatcgagcccagcagatctcatgtcctctctacctgtgc
ccacctttggaagccctggaggaagggggaccaccgcttacgctgggcctggagggagag
caccagcggaccaatgctgccttggccttgcagctggcccactgttggctgcagcagcag
gaccaccagcgcactggggatctgaaggtgtccaggcccagcctcccgtggcagctgccc
ctggcaccgacattccagctcacatcccacatgcggctcgggcttcggaacacggagtgg
ctgggccggactcaggtgctgcgacgcgggcccgttacctggtacctggatggtgcgcac
acctccagcagcattcaggcctgtgtgcgctggttccgccaggcgctgcagggcggcgag
aggcagagctgtgggccagaagtgcgtgtcttgcttttcaactccactggggaccgggac
tccgcagccctgctgaagctgctacagccctgccagtttgactatgctgtcttctgcccc
aacctgacagaggtatcatccccaggcagtgcagaccagcagaatttcacagtgacactg
gaccaggtgatacttcgctgcctagaacaccagcaacactggaaccacctggatgaggag
caggccagtccggacctctggagcaccccggccttggagcctggtgggcctgcacctctg
ctgctggcgcctcacccaccccacagctgcagcagcagctcccttgtcttcagctgcatc
tcccacgccttgcagtggatcagccaaggccgggaccctgtctttcaaccccctagctcc
ccaaggggcctccttgcccaccctgtggcaggtagtggggccagtgtactccgcgaagct
gctgctatccacgtgctggtcaccggcagcctgcaccttgtaggtggtgtcctgaagctg
ctggaaccctccctgtcccagtag
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