Otolemur garnettii (small-eared galago): 100955166
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Entry
100955166 CDS
T07855
Symbol
PDHA2
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
oga
Otolemur garnettii (small-eared galago)
Pathway
oga00010
Glycolysis / Gluconeogenesis
oga00020
Citrate cycle (TCA cycle)
oga00620
Pyruvate metabolism
oga00785
Lipoic acid metabolism
oga01100
Metabolic pathways
oga01200
Carbon metabolism
oga01210
2-Oxocarboxylic acid metabolism
oga04066
HIF-1 signaling pathway
oga04922
Glucagon signaling pathway
oga05230
Central carbon metabolism in cancer
oga05415
Diabetic cardiomyopathy
Module
oga_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
oga00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
100955166 (PDHA2)
00020 Citrate cycle (TCA cycle)
100955166 (PDHA2)
00620 Pyruvate metabolism
100955166 (PDHA2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
100955166 (PDHA2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
100955166 (PDHA2)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
100955166 (PDHA2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
100955166 (PDHA2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
100955166 (PDHA2)
Enzymes [BR:
oga01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
100955166 (PDHA2)
BRITE hierarchy
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Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
100955166
NCBI-ProteinID:
XP_003798543
LinkDB
All DBs
Position
Unknown
AA seq
391 aa
AA seq
DB search
MRKMLAAFVSRVRSSVVQKPARRVLVASYNYSNDATFDIKKCDRYLLEQGPPVSAVLTRQ
DGLKYYRMMLVIRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVITSYR
AHGVCYTRGISVRSILAELTGRRGGCAKGKGGSMHMYTKNFYGGNGIVGAQGPLGAGIAL
ACKYQGNKEICLTLYGDGAANQGQIAEAFNMAALWKLPCIFICENNLYGMGTSIERAAAS
TDYYKRGGFIPGLRVDGMDFLCVREATKFAADYCRSGKGPFLMELQTYRYHGHSMSDPGI
SYRTREEIKNIRSKSDPIMLLQDKMVNSKLATVEELKEIEAEVRKEIEDAAQFATADSEP
PLEEIGHHIFSSEPPFEVRGANPWIKFKSIS
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctggctgcctttgtctcccgagtgaggtcgagtgttgtccagaagcca
gctcgcagagtgctggtggcgtcttataactattcaaacgatgctacgtttgacattaag
aaatgcgatcgatatctgttggaacaggggcccccagtcagcgcagtactcaccaggcag
gatgggctcaaatactacaggatgatgctggtgattcgccgcatggagctgaaggcagat
cagctgtataagcagaaatttattcgtggtttctgtcacttgtgtgatggccaggaagct
tgctgtgtgggcctcgaggccggcataaacccttcggatcatgtcatcacgtcctatcgg
gctcatggcgtgtgctacactcgtggaatttccgtccgatcaattctcgcagagctgaca
ggacgcagaggaggttgtgctaaaggtaaaggaggatctatgcacatgtatactaagaac
ttctatgggggcaatggcattgttggggcgcaggggcccctgggggccgggattgctcta
gcctgcaaataccagggaaacaaggagatctgtttgactttgtatggggatggtgctgcc
aatcaggggcagatagccgaagctttcaacatggcagccctgtggaaattaccttgtatt
ttcatctgtgaaaataacctgtatggaatgggaacatctattgagagagccgcagccagc
accgattactacaaaaggggcggatttatccctgggctgagggtagatggaatggatttt
ctgtgtgttcgggaggcgacgaagtttgcagccgactattgcaggtctggaaagggacct
ttcttgatggagctgcagacctaccgttatcatggacacagtatgagtgatcctggaatc
agttaccgcacacgagaagaaattaagaatatcagaagtaagagtgatcccattatgctt
ctccaagataaaatggtaaacagcaagcttgccactgttgaagaattaaaggaaattgaa
gctgaagtgaggaaggaaattgaggatgcagcccagtttgccacagctgattctgaacca
cctttggaggaaataggccatcacatcttcagcagtgaaccaccttttgaagttcgtggt
gcaaatccatggatcaagtttaagtccattagttaa
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