KEGG   Otolemur garnettii (small-eared galago): 100956564
Entry
100956564         CDS       T07855                                 
Symbol
ATIC
Name
(RefSeq) bifunctional purine biosynthesis protein PURH
  KO
K00602  phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
Organism
oga  Otolemur garnettii (small-eared galago)
Pathway
oga00230  Purine metabolism
oga00670  One carbon pool by folate
oga01100  Metabolic pathways
oga01523  Antifolate resistance
Module
oga_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:oga00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    100956564 (ATIC)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    100956564 (ATIC)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    100956564 (ATIC)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:oga04147]
    100956564 (ATIC)
Enzymes [BR:oga01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.3  phosphoribosylaminoimidazolecarboxamide formyltransferase
     100956564 (ATIC)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.10  IMP cyclohydrolase
     100956564 (ATIC)
Exosome [BR:oga04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   100956564 (ATIC)
SSDB
Motif
Pfam: AICARFT_IMPCHas MGS Ribosomal_L12_N
Other DBs
NCBI-GeneID: 100956564
NCBI-ProteinID: XP_003785022
Ensembl: ENSOGAG00000005039
UniProt: H0WR69
LinkDB
Position
Unknown
AA seq 592 aa
MAPGQLALFSVSDKTGLVEFARTLTSLGLNLIASGGTAKALRDAGLAVRDVSDLTGFPEM
LGGRVKTLHPAVHAGILARNTPEDNADMARLDFSLIRVVVCNLYPFVKTVACPDVTVQEA
VEQIDIGGVTLLRAAAKNHARVTVVCDPDDYAPVSTEMQSSESKDTSLETRRQLALKAFT
HTAQYDEAISDYFRKQYSKGISQMPLRYGMNPHQTPAQLYTMKPVLPITVLNGAPGFINL
CDALNAWQLVKELKEALGVPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLWDTLTPIA
TAYARARGADRMSSFGDFVALSDVCDVPTAKIISREVSDGIIAPGYEEAALKILSKKKSG
NYCVLQMDQSYEPDENEIRTLFGLRLSQKRNDAVINKSLFTNVVTKNKHFSESAIRDLIV
ATVAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPRVLSMKFKP
GVKRAEISNAIDQYVTGTIGEDEDLMKWKALFEEVPELLTEAEKKEWINKLSDVSVSSDA
FFPFRDNIDRAKRSGVAYIAAPSGSAADKVVTEACDELGITLAHTNVRLFHH
NT seq 1779 nt   +upstreamnt  +downstreamnt
atggctcccggccagctcgccctattcagtgtctctgacaaaaccggccttgtggaattt
gcgagaaccctaacttctctgggtttgaatctcattgcttccggagggactgcaaaagct
ctcagggatgctgggctagccgtgagagatgtctctgatctgacaggatttcctgaaatg
ttggggggtcgtgtgaaaactttgcaccctgcagtccatgcaggaatcctggctcgtaat
acccccgaagataatgctgacatggccagacttgatttcagtcttataagagttgttgtt
tgcaacctgtacccctttgtgaagacggtggcctgtccagatgtaactgttcaggaggct
gttgagcaaattgatattggtggagtaaccttactgagagctgcagccaaaaaccatgct
cgggtgacagtggtgtgtgacccagatgactacgcgccagtgtccacagagatgcagagc
tccgagagtaaggatacctccctggagactagacgccagctagccttgaaggcattcact
cacacggcacagtatgatgaagcaatttcagattacttcaggaaacagtacagtaaagga
atatctcagatgcccttgaggtatggaatgaaccctcatcagactcctgcccagctgtac
acgatgaagcccgtgcttcccatcacagttctaaatggagcccctggatttataaactta
tgtgatgctttgaatgcctggcagctggtgaaggaactgaaagaggcattaggcgttcca
gccgctgcctctttcaaacatgtcagcccagcaggtgcagctgttggaattccactcagt
gaagatgaagccaaagtctgcatggtctatgatctctgggacaccctcactcccatagca
actgcatatgcacgagcaagaggtgctgataggatgtcttcatttggtgattttgttgca
ttatctgatgtttgtgatgtaccaactgcaaaaattatatccagagaagtatctgatggt
attattgccccaggatatgaagaagcagccttgaaaatactttctaaaaagaaaagtgga
aactactgtgtgcttcagatggaccagtcttatgaaccagatgaaaatgaaattcgaacg
ctctttggtcttcgtttaagccagaagagaaatgatgctgtcatcaacaagtcattattt
accaatgttgtaaccaagaataaacatttttcggagtctgccatcagggacctcatcgtg
gccaccgttgctgtcaagtacactcagtcaaattctgtgtgctacgccaagaacgggcag
gtcattggcattggagcaggtcagcagtctcggatccactgcacacgccttgcaggggac
aaggcaaactattggtggctgagacaccatccacgtgtgctttcaatgaagtttaaacca
ggagtgaagagagcagaaatctccaatgccatcgaccaatatgtgactggaaccattggc
gaggatgaagatttgatgaagtggaaggcactgtttgaggaggtgcctgaattactaact
gaggccgagaagaaggaatggattaacaaactaagtgacgtttctgttagctctgatgcc
ttctttcctttcagggataatatagacagagctaaaaggagcggcgtggcctacatcgct
gctccctccggctctgctgctgacaaagtcgtgacggaggcttgtgatgaactgggaata
accctcgctcacacgaatgtccggcttttccaccactga

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