Otolemur garnettii (small-eared galago): 100956811 Help Entry 100956811         CDS       T07855                                  Symbol TSC2 Name (RefSeq) tuberin isoform X3   KO K07207   tuberous sclerosis 2 Organism oga  Otolemur garnettii (small-eared galago) Pathway oga04072   Phospholipase D signaling pathway oga04115   p53 signaling pathway oga04140   Autophagy - animal oga04150   mTOR signaling pathway oga04151   PI3K-Akt signaling pathway oga04152   AMPK signaling pathway oga04211   Longevity regulating pathway oga04218   Cellular senescence oga04714   Thermogenesis oga04910   Insulin signaling pathway oga04919   Thyroid hormone signaling pathway oga05163   Human cytomegalovirus infection oga05165   Human papillomavirus infection oga05168   Herpes simplex virus 1 infection oga05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:oga00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     100956811 (TSC2)    04151 PI3K-Akt signaling pathway     100956811 (TSC2)    04152 AMPK signaling pathway     100956811 (TSC2)    04150 mTOR signaling pathway     100956811 (TSC2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     100956811 (TSC2)  09150 Organismal Systems   09152 Endocrine system    04919 Thyroid hormone signaling pathway     100956811 (TSC2)   09149 Aging    04211 Longevity regulating pathway     100956811 (TSC2)   09159 Environmental adaptation    04714 Thermogenesis     100956811 (TSC2)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     100956811 (TSC2)   09172 Infectious disease: viral    05163 Human cytomegalovirus infection     100956811 (TSC2)    05165 Human papillomavirus infection     100956811 (TSC2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:oga01009]     100956811 (TSC2) Protein phosphatases and associated proteins [BR:oga01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      100956811 (TSC2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Tuberin DUF3384 Rap_GAP Cnd1 Motif Other DBs NCBI-GeneID:  100956811 NCBI-ProteinID:  XP_012661213 Ensembl:  ENSOGAG00000016605 LinkDB All DBs Position Unknown AA seq 1789 aa AA seqDB search MAKPASKDSGLKEKFKILLGLGTSRPNPRSAEGKQTEFIITAEILRELSVECGLNNRIRV IGQICEVAKTKKFEEHAVEALWKAVADLLQPERPPEARHAVLALLKAIVQGQGDRLGVLR ALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELAEFVLQWMDVGLSSEFLLVL VNLVKFNSCYLDEYIASMVHMICLLCIRTVSSVDIEVSLQVLDAVVCYNCLPAESLPLFI ITLCRTINVKELCEPCWKLMRNLLGTHLGHSAICNMCRVMEDRTYMEDAPLLRGAVFFVG MALWGAHRLYSLKNSPTSVLPSFYQAMTSPNEVVSYEIVLSITRLIKKYRKELQAVTWDI LLNIMERLLQQLQCLDSPELKTIVHDLLTTVEELCDQNEFHGSQERYFELVERYADQRPE SSLLNLISYRAQSIHPAKDGWIQNLQMLMERFFRSESRGAVRIKALDVLSFVLLINRQFY EEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMAHSLS PPPELEERDVAAHSASLEDVKTAVLGLLVILQTKLYTLPASHAMRVYETLVSHLQLHYKH SYTLPIASSIRLQAFDFLLQLRADSLHRLGLPSKDGGVRFSPYCLCDCMEPERGPEKKAS GPLSPPTGPPGPGSTGPAVRLGYLPYSLLFRVLLQCLKQETDWKVLKLVLSKLPESLRYK VLIFTSPCSVDQLSSALCSMLSGPKTLERLRGTPEGFSRTDLHLAVVPVLTALISYHNYL DKTKQREMVYCLEQGLIYRCAGQCVVALSICSVEMPDIIIKALPVLVVKLTHISATASMA IPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRC RLPFRKDFVNFITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSLRIARPPKQGLNNS PPVKESKESCAAEAFRCRSISVSDHVVHSRIQTSLTSASLGSADENSMAQADDNLKNLHL ELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSL LGLDSGELQGSPESSSDRGVHVRQTKEAPAKLESQAGQQVSRGARDRVRSMSGGHGLRVG ALDVPAAHFPGGPASPGPQTAPAMKPEKASAAAQIPVQEKATLAACVPLLTQGWAEILVR RPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHRDTALYKSLSVPAAST AKPPPLPRSNTDSAVVMEEGSPGEAHMPGEPPELEDLEAALGTDRHCGHASAYSRSSSTS SQEEKSFHTEELAAGGIPIERAVSSGGGRPSVDLPFQPSQPLSKSSSSPELQTLQDILGD PGDKPDVSRLSPEAKVRSQSGTLDRDGAAWSVPGEESRCLGPAQPEGALPSSVPRSPSGL RPRGYTISDSAPSRRGKKVERDTFTSRAAASNAEKVPGINPSFVFLQLYHSPFFGDESNK PILLPSESFERSVQLLDQIPSYDTHKLAVLYVGEGQSNSELAILSNEHGSYRYTEFLTGL GKLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKK RHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIITPLDYECNLVSLQCRKDMEGLVDTS VAKIVSDRNLPFMARQMALHANMASQVHHSRSNPTDIYPSKWIARLRHIKRLRQRIREEA HYSNPSLPLTHPPAHTKAPAQAPVETTPTYETGQRKRLISNVEDFTEFV NT seq 5370 nt NT seq  +upstreamnt  +downstreamnt atggccaagccagcaagcaaagattcaggcttgaaggagaagttcaagattctgttggga ctgggaacatcaaggccaaatcccaggtctgcagagggcaaacagacagaatttatcatc acagcagaaatcctgagagaactgagtgttgaatgtggtctcaacaatcggatccgggtg atagggcagatttgtgaagtcgcaaaaactaagaaatttgaagagcacgcagtggaagca ctctggaaggcagtcgcagacttgctgcagccggagcggccaccagaggcccggcatgca gtgctggctcttctgaaggccatcgtgcaagggcagggtgaccgcttgggggtccttcga gccctcttttttaaggtcatcaaggattacccttccaatgaagacctccatgaaaggctg gaagtttttaaggccctcacagacaatgggagacacatcacctacttggaggaagaactg gctgagtttgtcctgcagtggatggatgttggcttgtcctcagaattccttctggtgctg gtgaacttggtcaaattcaacagttgttaccttgatgaatacatcgcatcaatggttcac atgatatgtctgctgtgcatccgaactgtgtcctccgtggacatagaggtctctctgcag gtgctggatgctgtggtctgctacaactgcctgccagctgagagcctccctctgttcatc atcaccctgtgccgcaccatcaatgtcaaagagctctgtgagccttgctggaagctgatg cgtaacctgctgggcacccacctgggccacagtgccatctgcaacatgtgccgtgtcatg gaggatagaacctacatggaagatgcgccattgctgagaggtgctgtgttctttgtgggt atggctctgtggggagcccaccgactgtactctctgaagaactcaccaacttctgtgctg ccatcattttatcaggccatgacctctccaaacgaggtggtgtcctatgagattgtcctg tcaataaccagactcattaagaagtacaggaaggagctccaggccgtgacatgggacatt ctgttgaacatcatggaacggctgctccagcagctccagtgcctggatagcccagaactg aagacgattgtccacgacttgctgaccacagtggaggagctatgtgatcagaatgagttc cacggctctcaggagagatacttcgagctcgtggagagatacgcagatcagagacctgag tcctccctcttaaacttaatatcctacagagctcagtcaattcatccggcaaaggatggt tggattcagaacctgcagatgttgatggagagattcttcaggagtgagtctcgtggtgct gtgcgcatcaaggcactggatgtgctgtcctttgtgctgctcatcaataggcagttctac gaggaggaactgattaactcagtggtcatctcacagctgtcccacatccccgaggataaa gaccaccaggtccgaaagctagccacccagctgttagtagacctagcagaaggctgccac acccaccacttcaacagtctgctggatatcattgagaaagtgatggcccactctctctca ccaccccctgagctagaagaaagggatgtggctgcacactcagcttccttggaggatgtg aagactgctgtcctggggctcctggtcatccttcagaccaagctgtataccctgcctgcc agtcatgccatgcgtgtatatgagactctcgtcagccacctccaactccactacaagcac agctacactctgcccattgccagcagcatccgactacaggcctttgacttcttgctgcag ctgcgggctgactctctgcaccgccttggcctgcccagcaaggatgggggcgtgagattc agcccctactgcctctgtgactgcatggagcctgagagaggccctgagaagaaggccagt ggccctctttcacctcccacagggccacctggcccagggtctacaggccctgctgtgcgg ctgggctacctgccctactccctgctcttccgagtcctgttgcagtgtttgaaacaggag actgactggaaggtgctaaagttggtcctcagcaagctgcctgagtcactacgctacaaa gtcctcatcttcacttctccctgcagcgtggaccagctgtcttctgccctctgctccatg ctttcaggcccaaagacccttgagcggctacgaggtaccccagaagggttctctagaact gacctgcatttggctgtggttccagtgctgactgcgttaatctcttaccataactatttg gacaaaaccaaacagcgtgagatggtttactgcctggagcaaggcctcatataccgctgt gctggccagtgtgtggtcgccttgtctatctgcagcgtggaaatgcctgacatcatcatc aaagcactgcctgtcctggttgtgaagctcacacacatctcggccacagccagcatggcc atcccactgctggaattcctgtccacgctggctaggctgccacacctgtacaggaacttt gctgcggagcagtatgcgagtgtgtttgccatctccctgccatacaccaacccctccaag ttcaatcagtacatcgtgtgtctggcccaccacgtcatagccatgtggttcattagatgc cgcctgcccttccggaaagattttgtcaatttcatcactaagggcttgcgctccaatgtc ctcctgtcttttgatgacactcctgagaaggacagcttcagagcacggagcaccagtctc aatgaaaggcccaaaagtttgaggatagccagaccccccaaacaaggcttgaataactct ccacctgtgaaagaatccaaggagagctgtgcagccgaggccttccggtgccgcagcatc agtgtgtctgaccatgtggtgcacagcaggatacagacatccctcaccagtgctagcctg gggtctgcagatgagaactccatggcccaggctgatgacaacttgaaaaatctccacctg gagctcacagaaacgtgtctggacatgatggcccgatatgtgttctccaacttcacagca gttcccaagaggtctcctgtgggagagttcctcctggcaggcggcaggaccaaaacctgg ctggttgggaataaactcgttactgtgacaacgagtgtgggaactgggacccggtcatta ctaggcctggattcaggggagctgcagggcagcccagagtcaagctctgatcgcggtgtg catgtgagacagacaaaggaggcgccagccaaactggagtctcaggctgggcagcaggtg tcccgtggggcccgggaccgagtccgctccatgtcagggggccacggtcttcgagttggt gccctggatgtgccagctgcccacttcccaggtggccctgcttctccaggaccacagaca gcaccagccatgaagcctgagaaggcatcagcggcagcccagatcccagtgcaggagaag gcaaccctggcggcatgtgtgcccctgctgacccagggctgggcagagatcctggtccgg aggcccacagggaacaccagctggctgatgagcttggagaacccactcagccccttctcc tcggacatcaacaacatgcctctgcaggagctgtccaatgccctcatggctgccgagcgc ttcaaggagcaccgagacacggcactatacaagtcactgtcagtgccagcagctagcaca gccaagcctccccctctccctcgctctaacacagactccgctgtggttatggaagaggga agtcctggagaggctcacatgccaggggaaccccctgaattggaggacttggaggcagct ctgggcacagacaggcactgtgggcatgccagcgcatatagcaggtcgtcttcaacctcc agccaggaggagaaatcattccacacagaagagctggctgctggggggattcccatcgag cgagcagtctcatctgggggtggccggccctctgtggacctccccttccagccttcccag cccctgagcaagtccagctcctcacccgaactgcagaccctgcaagacatccttggggac cctggggacaaacctgatgtcagccggctgagccctgaggccaaggtccggtcacagtca gggacactggacagggatggtgctgcctggtctgtcccaggtgaagagagccgatgcctg ggtccagcccagcccgagggtgccctgccttccagcgtcccccgctcacctagtggcctc cggcctcggggttacaccatctctgactcagccccatcacgccggggcaagaaggtagag agggacaccttcaccagcagagcagcagcctccaatgctgagaaagtgccaggcatcaac cccagctttgtgttcctgcagctgtaccactctcctttctttggtgatgagtccaacaag cccattctgttgcccagtgagtctttcgagcggtcagtgcagctcctcgaccagatcccg tcctatgacacacacaaacttgcagtcctatatgtgggagagggccagagtaacagtgag ctcgccatcctgtccaatgagcacggctcatacagatacacggagttcctgacaggcctg ggcaagctcatagagctcaaggactgccagccagacaaggtctacttaggcggcctggat gtgtgtggcgaggatggccaattcacctattgttggcacgacgacatcatgcaggctgtg ttccacatcgccacactgatgcccaccaaggatgtggacaaacaccgctgtgacaagaag cgccacctgggcaacgactttgtttccattgtctacaatgattctggagaggacttcaag ctgggtaccatcaaaggccagttcaattttgtccatgtgatcattaccccactggactac gagtgcaacctggtgtcactgcagtgccggaaagatatggagggccttgtggacaccagc gtggccaagattgtgtcagatcgtaacctgcccttcatggcccgccagatggccctgcat gccaacatggcctcacaagtgcatcacagccgctccaaccccactgacatctatccctcc aagtggatcgcccggctacgccacatcaagcggctccgccaacggatccgcgaggaagcc cactactcaaatcccagcttgcccctgacacatcccccagcccacaccaaagccccagca caggcaccggtggagaccacacccacctatgagacaggccagcggaagcgcctcatctcc aatgtggaggacttcacagagttcgtgtga

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