| Entry |
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| Symbol |
SETX
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| Name |
(RefSeq) probable helicase senataxin isoform X2
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| KO |
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| Organism |
oga Otolemur garnettii (small-eared galago)
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| Pathway |
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| Brite |
KEGG Orthology (KO) [BR:oga00001]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
100957240 (SETX)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:oga03021]
100957240 (SETX)
Enzymes [BR:oga01000]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
100957240 (SETX)
5.6.2.5 RNA 5'-3' helicase
100957240 (SETX)
Transcription machinery [BR:oga03021]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
100957240 (SETX)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
2681 aa
MSTCCWCTPGGLSTVDFLKCYASKIQSSEFQTADEDLCYCLECVAEYHKARDELPYLHEV
LWELETSRLVNHFEKSMKAEIGDDDELYIVDNNGEAQLFDFTGQDFENKLRVPLLEILKY
PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK
VDRDDYYDLQDVLTCLFKVIELGLLESPDIYTTSVLEKGKLILLPSHMYDTTNYKNYWLG
ICMLLTILEEQAMDSLLLGSDKQNNFMQSILHTMERQSDDDSVDPFWPALHCFMVILDRL
GSKVWGQRIDPIEALQTIINNGSYNREIQNIRNSSVRTKLEPESHLDDMVTCSQIVYNYN
PEKTKKDSGWRSAICPDYCPNMYEEMETLANVLQSDIGQDMRVHNSTFLWFIPFVQSLMD
LKDLGVAYIAEVIHHLHSEVKDVLNQADAVCDKVTEFFLLILVSVIELHRNKKCLHLLWS
SSQQWVEVVVKCSKLPTTAFARSSEKSSGNCSKGTAIISSLSLHSMPSNSVQLACVQLIR
SLLKEGYQLGQQTICKRFWDKLNLFLRGNLSLGWQLTSQETHELQACLKQIIRNIKSKVP
PCSTLVDLTLAGKTPPASYNKEESEEIGKKSIKDIHCVENSSPTFSKEPMKGDIYQVPES
TLIKASNTMEEEDDEDNYIIKDLKLEDHLSAESCLKQSSISLHTEKAKARVKISRGKRKS
VKENSSYIPQNCTSRNDPKKGSDRGIIIPTHLLTDSSAESLEKVSTSNEDFSLKDDTLGK
TSKPKTKAQKDEICAKLSHVIKKQHRKSTLVGNAISLEENLTASNTESFYVRKDTGVQKG
DSFIHNLSVDPNGILDDNKNGEQNSVNSLLPKKKQLKNEELGIFSLNENSFKIQKCHLDD
KDLVSFIEMTDNLVKKMSPFNDPVTVLESRDKERSKSIDLISSNLTGEQAPDISAKSDIL
TDSQVDRDLHKLSLIAQASVIKFPSDSTQKSPSQLQRKVKDDKRCFTANQNNVGDTCHGQ
VIIISDSDDDDDERILGLEKHIKQDKICIKKEYPEQCVSIVNSNVEKKLIKEEQTKSLDF
EESDSQSFEFESSSEMFSVWQDHKLNKKNSVQEEEKKSCLTDLSDITNDWGYDTDYVPEE
VTKKVERIKGHKEPQRGSISVEKICEIEVKKPKRKRSEKPTAEDPLRPSSSVRNEDQSHT
PIEREIPENDFKKSVDTKPTTPSSNIQRATTVTPKKSSPKPHHSEPVRRGPLSKTSKRAA
HSDAKKGQSKNLNYLSCRTTPAIVPPKKFRPCPEPASTVEKLGLKKAPRKAFELSQRSLE
YLVQLRDHGKSVGVIDTRKKTKLISPQTLTVKNNKKLLTSQDLQLQRQMRSKSKKNRRGG
FDCESTDTTRAGPQTAQTSDKLVPESDRSDYTGRTEVLANNNRKQLVKCMSSEPETVKAN
SVFQATDACLLNQCDSTVLNGRIPTNEILVSPSEDALGGGGLPVHHTKVANLKVAEPESD
SDTEADNLFLTQNDPEDMDLCSQVENNKVIELVFGKNTVEVEEGSVSRPQLESLSGTKCK
YKDCVETAKNQGVYCSKHCEAKAADEDVFRKPALPLSASKPLRPSTAKIFSSSSTSRIAN
LSKTLESTSALKNKPNGVQSILKVPQPAPLISLKPMGEMKIPCNILHSQTPNNSSRPGYK
LPFSENKSFPTSSPVNILLSSQSISDTFVKEVLKWKYEMFLNFDQCGPPASLCQSISRPV
PVRFQDCGDYFNVFFPLMVLNTFETVAQEWLSSPNKEIFYRLNLRKFPADYKKCWEFVVY
LEEGDLAKQLHPKENDLVFLVPERQNGEKKDTVRNCTKDLYEYHCGYVHKFRRTSVMRNG
KSECCLSIQTQDNLPANLNEFVTCIVISSLVTTQRKLKAMSLLSGRNQLARAVLNPNPMD
FCTKDLLTTTSERIIAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTI
VGLLYRLLTENQRRGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKN
PLGNCGDINLVRLGPEKSINNEVLKFSLDSQVNHRMKKDLPSHVQEMHRRKEFLDHQLDE
LSRQRALCRGGREIQRQELDEKIAKVSKERQELASKIKEVQGRPQKTQSIIILESHVICC
TLSTSGGLLLESAFRGQGGVPFSCVIVDEAGQSCEVETLTPLIHRCNKLILVGDPKQLPP
TVISMKAQEYGYDQSMMARFYKLLEENVEHNMIGRLPVLQLTVQYRMHPDICLFPSSYVY
NRNLKTNRQTEAIRCSADWPFQPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKLIKEK
RKDVTFRNIGIITHYKAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRAN
AMQGSIGFLASLQRLNVTITRAKYSLFILGHLRTLMENQHWNYLIQDAQKRGAIIKTCDK
NYRHDAMKILKLKPVLQRSLTHPPTIVPEVSRPQGGLPSNKLDSGFARTSYAASLYHTPP
DGSESTVTSKDLERSPVQELRDPRLLRRMNAEAKGKFIRSPQPSSPQHPGATPPAEEPGF
PITHQDLECGVQQSTSKAATVSNHKPRVQCESPAASTDAANNKRKYSDLEEGLSHRRETR
APSEGEQEKQGSVTDHTKRNSSWDRRRQENEDSNSKKRKHT |
|---|
| NT seq |
8046 nt +upstreamnt +downstreamnt
atgagcacgtgttgttggtgtacaccaggtggtctttccaccgttgacttcctaaagtgc
tatgcatctaagatccaatccagtgaatttcagacagctgatgaagacctctgctactgc
ttagaatgtgtggctgaataccacaaagcaagagatgaattaccatacttgcatgaggtt
ttatgggaattggaaacctcacgtctggtaaatcactttgaaaaatccatgaaggcagaa
attggcgatgatgatgaattatatatagtagacaataatggagaggcacagttgtttgac
tttactggccaagactttgaaaataagcttcgagttcctcttcttgaaatactcaaatat
ccatacctgcttctacatgaacgtgttaatgaattatgtgttgaagcactttgtcggatg
gaacaggccaattgctcctttcaggtttttgacaaacatccagggatctatttgtttttg
gtccatcccaatgaaatggttcggcgctgggctatcctgactgcaagaaacttggggaaa
gtggacagagatgattattatgacttacaggatgttttaacttgcctttttaaagtcatt
gagttagggcttttggaaagtccagatatttatactacttctgtccttgagaagggtaaa
ctgattcttctgccctcgcacatgtatgatactaccaactacaaaaactactggttaggt
atttgcatgctgctgactattcttgaggagcaagccatggattctctgttgctgggctca
gacaaacaaaataattttatgcagtcaatacttcacactatggagagacaatcagacgat
gatagtgtggatcctttttggccagcattacactgtttcatggtgattctggatcgcctg
ggatctaaggtctggggtcaacgtattgaccctattgaggcattgcaaaccattatcaac
aatggaagctacaatagagagatccagaacatccgaaatagctctgtgaggaccaagttg
gaaccggaatcacatttggatgatatggtgacttgcagtcagattgtatacaattataat
cctgaaaagaccaaaaaggattctggatggagatctgccatttgcccagattattgtcct
aacatgtatgaagaaatggaaacattagccaatgtacttcagtcagatatcggtcaagac
atgcgtgttcataacagcacatttctgtggttcataccttttgttcagtctctcatggat
cttaaagatttgggtgttgcttacatagcagaggttattcatcatctgcactccgaagtc
aaagatgttctcaaccaagcagatgctgtgtgtgacaaagtcactgaattttttcttcta
attttggtatcagtgattgaactgcacagaaataaaaaatgtttgcatttgctatggagt
agttcccagcagtgggtggaagtagttgtgaaatgttccaaacttcctaccactgcattt
gcacggagttctgagaagtcatctggaaattgctccaaaggaacggcaatcatatcatca
ctgtcactgcattcaatgccgtctaactctgtacagcttgcttgtgtgcagctgattaga
agtctccttaaagaaggttatcagcttggacagcaaactatttgtaaacgattttgggat
aagcttaacttattccttcggggaaatttatctctaggttggcagttgactagtcaggag
acccatgaattacaagcttgtttaaaacaaattattagaaacataaaatcaaaagtacct
ccatgtagcactttggtggatctgactctggcaggtaaaacccctcctgcatcttacaat
aaagaagaaagtgaagaaatagggaagaagtctataaaagatattcattgtgtggaaaat
tccagcccaacattttctaaagaaccaatgaaaggtgatatatatcaagtgccagagagt
acactgatcaaagcaagtaacactatggaagaagaggatgatgaggataattatattata
aaggatttgaaactagaagaccatctctcagctgagtcatgtttaaagcagagtagtata
agccttcatactgaaaaagctaaagctcgagttaaaataagtagagggaagcggaagtct
gtaaaagagaattcctcgtatataccacagaattgtacttcaagaaatgacccaaaaaag
ggaagtgacagaggaataataataccaacacatttgttgactgattctagtgctgaatct
ctggagaaagtgtctacatcaaatgaggatttctctttaaaggatgatactcttggtaaa
acctcaaaaccaaaaactaaggcacagaaagatgaaatctgtgcaaaattatcacatgta
ataaagaagcaacacaggaaaagtactttggtcggtaatgctatcagtttagaggaaaac
ctaactgcatctaacactgagagtttctatgtaaggaaggatacaggagttcagaaaggg
gacagctttatacacaacctgtctgtagatcctaatggtattctggatgataataaaaat
ggagaacaaaattctgtaaacagtttattaccaaaaaagaaacaattaaagaatgaagag
ttgggtattttctctttaaatgaaaacagttttaaaatacagaaatgtcatcttgatgat
aaagatttggtctcatttatagaaatgaccgataatttagtgaagaaaatgtctcccttt
aacgatccagtgactgtacttgaatcaagagataaggaaaggagtaagagtattgatctg
atttcttctaacctgacaggggaacaagcacctgacatcagtgctaaatctgatatctta
acggattctcaggtagacagagacctccacaaattatctttaatagctcaagccagtgtt
attaagtttccatcagattcaactcaaaaaagcccatcccagctccaaagaaaagtaaaa
gatgataaaagatgtttcacagctaaccagaataatgttggagacacctgccatggacag
gttattattatttcggattctgatgatgatgatgatgaaagaattctgggtcttgagaaa
cacattaaacaggacaaaatatgcattaagaaagaatatccggagcagtgtgtttcaata
gttaatagtaatgtggaaaagaagctaataaaggaggaacaaacaaagtctttggatttt
gaggaatctgattctcagtcttttgagtttgaaagttcatctgaaatgttttctgtttgg
caagatcataaattaaacaagaagaattcagttcaggaggaagaaaaaaagtcatgtttg
actgatttgtctgatatcacaaacgattggggctatgatacggattatgtacctgaagaa
gttactaaaaaagtagagcgcattaaaggacacaaagaaccacagagaggtagtatttct
gttgagaaaatttgtgaaattgaagtaaaaaaacctaagagaaaacgatctgaaaaacca
acggctgaagatcctctaaggccttcgtcttctgtcagaaatgaagaccagtctcatact
cctattgagagagagattcctgaaaatgatttcaaaaaaagtgtagacacaaagcctaca
actcccagttcaaatattcagagagccactacggttacaccaaagaagtcttctccaaag
cctcatcattcagaacccgttaggagaggtccactttctaaaacctccaagagagcagca
cattcagatgccaaaaaaggacagagtaaaaatttaaattacttaagttgtaggacaact
cctgcaatagtgccaccaaagaaatttcgcccctgtcctgagccagcctcaacagttgag
aaacttggtctgaaaaaggctcctcgtaaggcatttgagttgtctcagcgatctttagag
tatttagttcagttacgtgatcatggcaaaagtgttggagtaattgataccagaaaaaag
actaaattaatttctcctcagactctaactgtcaaaaataacaagaaactcttaaccagt
caagatctgcagttgcaaaggcagatgagatccaagtccaaaaaaaatagacgagggggt
tttgattgtgaaagtacagatactacaagagcagggccacagacagcacagacttctgac
aagcttgtaccagaatctgataggtcagattatacaggaagaacggaggtacttgccaac
aataatagaaaacagttagtaaaatgcatgtcttctgaaccagaaactgtaaaagcaaac
tctgtatttcaggcaactgatgcttgtcttttgaaccagtgtgattctacagtgttaaac
ggaagaataccaacaaatgaaatactcgtctctccttcagaggacgctttaggtggagga
ggtctaccagtacatcatacaaaggtggcaaatttgaaagtggcagaacctgaatctgac
agtgatacagaggcagataatttatttttaacacaaaatgatcctgaagatatggatttg
tgttcacaagtagagaataataaagtcattgaactagtttttggaaagaatacagttgag
gtggaagaaggttctgtaagtcggcctcagttggaatctttgagtggcacaaagtgtaag
tacaaagattgtgttgaaaccgcaaaaaaccagggcgtatactgctcaaaacactgtgaa
gctaaagcagcagatgaagatgtatttcgtaaacctgccttgcccctttctgcatccaaa
cctttaagaccttccactgctaagatttttagctcaagtagtacttcgcgaattgctaat
ctgtctaagactttggaaagtacttcagcactaaaaaataagccaaatggggtgcagtct
attttgaaagtaccacagccagctcctctaatatctctgaagccaatgggagaaatgaag
attccatgcaatattcttcattctcagactccaaataattctagcaggccaggttataaa
cttccttttagtgagaacaaatcttttccaacttcctctccagtaaacattctgttgtca
tcacagtctatctctgatacctttgttaaagaggtcttaaaatggaagtatgaaatgttt
ttgaactttgatcagtgtgggccccctgcaagtctttgtcagtccatctcaagacctgtg
cctgtcagatttcaagattgtggagattattttaatgtctttttccctttgatggtactg
aatacttttgaaacagtggcacaggaatggctcagctcccccaataaagagattttctat
cggttgaatttacgaaaatttcctgctgattataaaaaatgctgggaatttgtagtttac
ctggaggaaggtgatctggctaaacagcttcatccaaaggaaaatgatttggtgtttttg
gttcctgagagacaaaatggagagaaaaaagatacagtgagaaattgcacaaaggatctc
tatgaatatcattgtggttatgttcacaagtttcggcgtacttcagtcatgcgtaatggg
aaatctgagtgttgcctttccatccagactcaagataacttgccagccaatttaaatgaa
tttgtgacgtgtattgtaatcagttctctggtaactacacaaaggaaattgaaagccatg
tctctgttaagtggtcggaaccaactggctagagctgttctaaatccaaaccccatggac
ttctgtacaaaagatttactaactacaacatctgaaagaattattgcctacttaagagat
tttaacgaagaccaaaagaaagcaatagaaactgcatatgccatggtgaaacactcacca
tcagttgccaaaatctgcctgattcatggtccacctggaacaggaaaatcaaaaactatt
gttggcctcctataccgcttgctaacagagaaccagagacgggggcattcagatgaaaac
tccaatgccaaaatcaaacagaaccgtgtcctcgtgtgtgcaccttccaacgcagctgtt
gatgaactaatgaaaaaaattatccttgaattcaaagaaaagtgtaaagacaagaagaat
cctttgggaaactgtggagatataaatttagtacgactgggtccagaaaagtctattaat
aatgaagttctaaaatttagtttggacagccaagttaaccacagaatgaaaaaagattta
ccttctcatgttcaagagatgcatagaagaaaggagtttctagatcatcagctagatgag
ctttctcggcagcgagctttatgccgaggtggacgggaaatacagaggcaagaattagat
gaaaaaattgccaaagtttcaaaagaaaggcaagaacttgcttctaaaattaaggaggtt
caaggacgcccacagaaaacacagagtatcatcatcttagaatctcatgtcatctgctgc
acattgagcacaagtggtggtttactgctagagtctgcttttcgcgggcaagggggtgtt
cccttcagttgtgtcattgttgatgaggctgggcaatcttgtgaagttgagactctgact
ccgctaatccatcgctgcaacaagctgatcctagtaggagaccctaaacagctccccccc
acagtcatttcgatgaaagcacaggagtatggctatgaccagtcgatgatggctcgcttc
tacaaactgctggaagagaatgtagaacacaatatgattggcaggctacctgttttacag
cttactgttcagtacaggatgcatccagacatatgtctcttcccatctagttatgtttat
aacagaaacttgaaaacaaatagacagacagaagccattcggtgttcagcagactggccg
tttcaaccttacctggtatttgatgttggagatggatcagaaagacgggataatgactcc
tacataaatgttcaagaaattaaactggtgatggaaataattaagcttattaaagagaaa
agaaaggatgttacttttcgaaacattggcataataacccattataaggcccagaagaca
atgattcagaaggatttggacaaagagtttgatagaaaaggaccggcagaagtagacacc
gtggatgctttccagggtcgccagaaggactgtgttatcgtcacgtgtgttagagcaaat
gccatgcaaggttccattggattcctggcaagtttgcagagattgaatgtcaccattaca
cgagccaagtacagccttttcatccttggacatttaaggaccctaatggaaaatcagcat
tggaattacttgattcaggatgctcagaagcgtggtgccattattaagacctgtgacaaa
aactatagacatgatgcaatgaagattctgaaactcaaacctgtactacagagaagtctg
actcacccccccaccatagttccagaggtgtccagaccccagggcggcttgcccagcaac
aagctagacagcggatttgccagaacatcttatgctgcttctctgtaccacacaccccct
gacggtagtgaatctactgttacttcaaaggatcttgaaaggtcacctgttcaggagctc
cgagatccacgactgcttaggaggatgaatgccgaagccaaaggaaaattcatcaggagt
ccacaaccctcgagcccccagcatcctggagcaacacctcctgcggaagagccaggcttc
ccgatcactcaccaggatctggaatgtggtgtgcagcagtccacttctaaagcagccact
gtgagcaaccacaaacctcgtgtgcagtgtgaatctccagctgccagtactgatgctgcg
aataataagagaaaatacagtgacctggaagaggggctcagtcacaggagagagaccagg
gctcccagtgaaggggagcaggagaagcagggttctgtgactgatcacaccaagaggaac
tctagctgggataggaggagacaggagaatgaggacagcaattctaagaaaagaaaacat
acgtag |
|---|
