| Entry |
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| Symbol |
CACNA1B
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| Name |
(RefSeq) voltage-dependent N-type calcium channel subunit alpha-1B
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| KO |
| K04849 | voltage-dependent calcium channel N type alpha-1B |
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| Organism |
oga Otolemur garnettii (small-eared galago)
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| Pathway |
| oga04723 | Retrograde endocannabinoid signaling |
| oga05022 | Pathways of neurodegeneration - multiple diseases |
| oga05207 | Chemical carcinogenesis - receptor activation |
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| Brite |
KEGG Orthology (KO) [BR:oga00001]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100957337 (CACNA1B)
04020 Calcium signaling pathway
100957337 (CACNA1B)
09150 Organismal Systems
09156 Nervous system
04727 GABAergic synapse
100957337 (CACNA1B)
04725 Cholinergic synapse
100957337 (CACNA1B)
04728 Dopaminergic synapse
100957337 (CACNA1B)
04726 Serotonergic synapse
100957337 (CACNA1B)
04723 Retrograde endocannabinoid signaling
100957337 (CACNA1B)
04721 Synaptic vesicle cycle
100957337 (CACNA1B)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
100957337 (CACNA1B)
09164 Neurodegenerative disease
05016 Huntington disease
100957337 (CACNA1B)
05020 Prion disease
100957337 (CACNA1B)
05022 Pathways of neurodegeneration - multiple diseases
100957337 (CACNA1B)
09165 Substance dependence
05032 Morphine addiction
100957337 (CACNA1B)
05033 Nicotine addiction
100957337 (CACNA1B)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
100957337 (CACNA1B)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:oga04040]
100957337 (CACNA1B)
Ion channels [BR:oga04040]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
100957337 (CACNA1B)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
2334 aa
MVRFGDELGGRYGGAGGGERARGGGAGGAGGPGPGGLQPGQRVLYKQSIAQRARTMALYN
PIPVKQNCFTVNRSLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLPD
GDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFHKGSYLRNGWNVMDFVVVLTGILA
TAGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAII
GLEFYMGKFHKACFPNSTDTDPVGDFPCGKEPPARLCEGDTECREYWPGPNFGITNFDNI
LFAVLTVFQCITMEGWTDILYNTNDAAGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFA
KERERVENRRAFLKLRRQQQIERELNGYLEWIFKAEEVMLAEEDRNAEEKSPLDVLKRAA
AKKSRNDLIHAEEGEDRFADLCAVGSPFARASLKSGKTESSSYFRRKEKLFRFFIRRVVK
AQSFYWAVLCVVALNTLCVAMVHYNQPQRLTTALYFAEFVFLGLFLTEMSLKMYGLGPRS
YFRSSFNCFDFGVIVGSIFEVVWAAIKPGASFGISVLRALRLLRIFKVTKYWSSLRNLVV
SLLNSMKSIVSLLFLLFLFIVVFALLGMQLFGGQFNFKDETPTTNFDTFPAAILTVFQIL
TGEDWNAVMYHGIESQGGVSKGMFSSFYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTK
DEEEMEEAANQKLALQKAKEVAEVSPMSAANISIAARQQNSAKARSVWEQRASQLRLQNL
RASCEALYSELDPEERLRFATTRHLRPDMKTHLDRPLVVELGRDGPRAPPGGKARPEATD
ATEGADPPRRHHRHRDRDKAAAGEPDRADAPRAESGEPSARDERVRPHRSHSKEAAGPPE
ARGERGRGPGPEGGRRHHRRGSLEEATDREPRRHRAHRHACDQGKEGSAPTAKGERRSRH
RGGPRAGPREAESGEEPARRHRTRHKVLPAQDAAVKEAPEKEAEVAEVDKEKELRNHQPK
ELHCDLEASGTMGVGPVHTLPSTCLQKVEEQPEDADNQRNVTRMSSQPSDPSTTVHIPVT
LTGPPGETTVVSSGNVDPESQVEGKKEVEADDVMRSGPRPIVPYSSMFCLSPTNLLRRLC
HYIVTMRYFEMVILVVIALSSIALAAEDPVRTDSPRNNALKYMDYIFTGVFTFEMVIKMI
DLGLLLHPGAYFRDLWNILDFIVVSGALVAFAFSGSKGKDINTIKSLRVLRVLRPLKTIK
RLPKLKAVFDCVVNSLKNVLNILIVYMLFMFIFAVIAVQLFKGKFFYCTDESKELERDCR
GQYLDYEKEEVEAQPRQWKKYDFHYDNVLWALLTLFTVSTGEGWPMVLKHSVDATYEEQG
PSPGYRMELSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKVMSECSLEKNERACIDFA
ISAKPLTRYMPQNKQSFQYKTWTFVVSPPFEYFIMAMIALNTAVLMMKFYDAPYEYELML
KCLNIVFTSMFSMECVLKIIAFGVLNYFRDAWNVFDFVTVLGSITDILVTEIAETNNFIN
LSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGN
IALDDDTSINRHNNFQTFLQALMLLFRSATGEAWHEIMLSCLSNRACDERASASECGSDF
AYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAACGR
ISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISSEDMTVHFTSTLMALIRTAL
EIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVYAALMIFDF
YKQNKTTRDQIQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSLSNGG
AIQTQESGIKESVSWGTQRTQDTPCEAWAPLERGHSAEIPAMQPGVLAVDVQMQNMAMRA
PNGDPQPGLESQGRAASMPRLAAETQPVPDASPMKRSISTLAQRPHAAHLCSTALDRPPP
SQASHHHHHRCHRRRDKKQRPLEKGPSLSADVDGATGSAAGPGLPPGEGPASCRRERERR
QERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKLSLSSHPTSPTAGQEPGPHPKGS
GSVNGSPLPSASGASTPGRGGRRQLPQTPPTPRPSVTYKTANSSPVHFSGAQTSLPAFSP
GRLSRGLSEHNALLQTDPLGPPLVPSSRIGSDPYLGQRLDSEASAHTLPEDTLTFEEALA
TNSGRSSRTSYVSSLTSQSHPLRRVPNGYHCTLGLSSGGRARHSYHHPDQDHWC |
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| NT seq |
7005 nt +upstreamnt +downstreamnt
atggtccgcttcggagacgagctgggcggccgctatgggggcgccggtggcggggagcgg
gcccggggcggcggggccggcggggcgggcggcccgggccctgggggtctgcagcccggt
cagcgggtgctctacaagcagtcgatcgcgcagcgcgcgcggaccatggctctgtacaac
cccatcccggtcaagcagaactgcttcaccgtcaaccgctcgctcttcgtcttcagcgag
gacaacgtcgtccgcaaatacgccaagcgcatcacggagtggcctccattcgagtacatg
atcctggccaccatcattgccaactgcatcgtgttggcgttggagcagcacctccctgat
ggggacaagacacctatgtctgagcggctggatgacacagaaccctacttcatcgggatc
ttctgcttcgaagcagggattaagatcattgctctgggcttcgtcttccacaagggctcc
tacctgcggaatggctggaacgtcatggactttgtggtggtcctcaccgggattcttgcc
acagctggaactgactttgacctgagaactctgcgggctgtgcgtgtgctaagacccctg
aagctggtgtctgggattccaagtttgcaggtggtgctcaagtccatcatgaaggccatg
gttccactcctgcagatcgggctgcttctcttcttcgccatcctcatgtttgccatcatt
ggcctcgagttctacatgggcaaattccataaggcctgtttccccaacagtacagataca
gaccccgtgggtgatttcccctgtggcaaggagcccccagcccggctttgtgagggcgac
acggagtgccgggagtactggccaggacccaactttggtatcaccaattttgacaacatc
ttgtttgccgtcttgacagtgttccaatgcatcaccatggagggctggaccgacattctc
tacaatacaaatgacgctgctggcaacacctggaattggctctacttcataccactaatc
atcattggctccttcttcatgctcaacctggtgttgggtgtgttgtcaggagagtttgcc
aaggagcgagagagggtggagaatcgccgcgccttcctgaagctccgccggcaacagcag
atcgagagggagctcaatgggtacctggagtggatatttaaggctgaggaagtcatgctg
gcagaggaggacaggaatgcagaggagaagtcccctttggatgtgctgaagagagcagct
gccaagaagagtagaaatgacctgatccatgctgaggagggtgaggaccgctttgcagac
ctctgtgctgttggatcccccttcgcccgtgccagcctcaagagtgggaagacggagagc
tcatcatacttccggaggaaggagaagctgttcaggttcttcatccggcgcgtggtgaag
gctcagagtttctactgggcggtgctgtgcgtggtggccctgaacacgctgtgtgtggcc
atggtacactacaaccagccacagcggctcaccacggcgctgtactttgcggagtttgtt
ttcctgggtctcttcctcacagagatgtccctgaagatgtacggcctagggcccagaagc
tacttccggtcctccttcaactgctttgactttggggtcattgtgggcagcatcttcgag
gtggtctgggcggccatcaagccaggagcctcctttggtatcagcgtgctgcgggcgctg
cgcctgctgcggatcttcaaagtcaccaagtactggagctcgctgcgcaacctggtggtg
tccctgctcaactccatgaagtccattgtcagcctcctcttcttactcttcctgttcatc
gtggtcttcgctctgctggggatgcagctgtttgggggacagttcaactttaaagatgag
actccaacgaccaactttgacacgttccctgcagccatcctcactgtcttccagatcctg
accggagaggactggaacgcagtgatgtaccatggcattgaatcgcaaggtggggtcagc
aaaggcatgttctcatccttttacttcatcgtcctgacactgtttggaaactacactctg
ttgaatgtcttcctggccattgccgtggacaaccttgccaatgcccaggagctgaccaag
gatgaagaggagatggaagaagcagccaatcagaagcttgctcttcaaaaggccaaagaa
gtggccgaagtcagccccatgtctgctgcgaacatctccattgctgccaggcagcagaac
tcggccaaggcacgctcggtgtgggagcagcgggccagccagctgaggctgcagaacctg
cgagccagctgcgaggcgctgtacagcgagctggaccctgaggagcggctgcgcttcgcc
accacgcgtcacttgcggcccgacatgaagacgcacctggaccggccgctggtggtggag
ctaggccgggatggcccacgggcacccccagggggcaaggcccgacccgaggccacagat
gccaccgagggcgccgacccgccgcgcaggcaccaccggcaccgcgacagggacaaggcc
gctgcaggggaaccagacagagcagacgccccgagggcggagagcggagagcccagtgcc
cgtgatgagcgtgtgcggccccaccgcagccacagcaaggaagccgcgggccctccggag
gcgcggggcgagcgtggccggggtccaggccccgagggcggccggcgccaccaccggcgc
ggctccctggaggaggcgaccgatagggagccccggcgccaccgcgcgcaccggcacgcg
tgtgaccagggcaaggagggctccgcacccacggccaagggcgagcggcgctcgcgacac
cggggtggcccccgggccggccccagggaagcggagagtggggaggagccagcgcggcgg
caccggacacggcacaaggtgcttcctgcgcaggacgctgccgtgaaggaggcccctgag
aaagaggccgaggtcgctgaagtggacaaggagaaggagctccggaatcaccagcccaag
gagctgcactgtgacctggaggccagtgggacaatgggtgtgggccctgtgcacacactg
cctagcacctgtctccagaaggtggaggagcaaccagaggatgcagataatcagcgaaat
gtcactcggatgagcagtcagccctcagacccaagcaccacagtgcacatcccagtgact
ctgacgggcccccctggggagaccacggtggtttctagtggtaacgtggacccagagagc
caagtagaagggaagaaggaggtggaagctgatgacgtgatgaggagtggcccccggcct
attgtgccgtacagctccatgttctgcttaagccctaccaacctgctgcggcgcctctgc
cactacatagtgaccatgcgctacttcgagatggtcatccttgtggtcattgccctgagc
agcatcgctctggctgcagaggaccctgtgcggacagactctcccaggaacaacgctctg
aagtacatggactacatcttcacaggtgtcttcacctttgagatggtgataaagatgatt
gacttgggactgctacttcaccctggagcctacttccgggacctgtggaacattctggac
ttcattgtggtcagtggggccctggtggcgtttgccttctcaggatccaaagggaaagac
atcaacaccatcaagtccctaagagttctgcgcgtcctacggcccctcaagaccatcaaa
cggctccccaagctcaaggctgtgtttgactgcgtggtcaactccctaaagaatgtcctc
aacatcttgatcgtctacatgctcttcatgtttatctttgctgtcattgcggtccagctc
ttcaaaggaaagtttttttactgcactgatgaatccaaggagctagagagggactgcagg
ggccagtacttggattatgagaaagaggaggtggaagcacagccaaggcagtggaagaaa
tatgacttccactatgataacgtgctctgggccctgctgacattgttcacggtgtccaca
ggagaagggtggcccatggtactgaagcactcagtagatgccacctatgaggagcagggt
ccgagccctgggtaccgcatggagctatccatcttctacgtggtctactttgtggtcttc
cctttcttctttgtgaacatctttgtggccttgatcatcatcaccttccaagagcaaggg
gacaaggttatgtctgagtgcagcttggaaaagaatgagagggcttgcatcgactttgcc
atcagtgcgaagcccctgacgcggtacatgccccagaacaagcagtcattccagtacaag
acgtggacgtttgtggtctccccaccctttgagtacttcatcatggccatgatagccctc
aatacagcagtgctgatgatgaagttctatgatgctccctacgagtatgagctgatgttg
aaatgcctgaacattgtgttcacatctatgttctccatggaatgcgtgctgaagatcatc
gcctttggggttctgaactatttcagagatgcctggaatgtctttgactttgtcacagta
ttgggaagtattactgatattttagtaacagagattgcggaaacgaacaacttcatcaac
ctcagcttcctccgcctcttccgagcagcacggctcatcaagctgctgcgccagggctac
accatccgcatcctgctctggacctttgtccagtccttcaaggccctgccctacgtgtgt
ctgctcatcgccatgctcttcttcatctacgccatcatcgggatgcaggtatttggaaac
attgccctggacgatgacaccagcatcaaccggcacaacaacttccagacattcctgcaa
gccctgatgctgctgttcaggagtgccactggggaggcctggcacgagatcatgctgtct
tgtctcagcaaccgagcctgtgatgagcgggccagtgccagcgagtgtgggagtgacttc
gcctacttctactttgtctccttcatcttcctgtgctccttcctgatgttgaacctgttt
gtggctgtgatcatggacaattttgagtaccttacgcgggactcttccatcttagggcct
caccacctggacgagttcatccgggtctgggctgagtacgacccggctgcatgtgggcgc
atcagttacaatgacatgtttgagatgctgaaacacatgtccccacctctggggctgggg
aagaaatgccctgctcgagttgcgtacaagcgtctggtccgcatgaacatgcccatctcc
agtgaggatatgacggtccacttcacatctacgctgatggccctcatccggactgcactg
gagatcaagctggccccagctgggacaaagcagcatcaatgtgatgcagagctgaggaag
gagatttccgtggtgtgggccaacctgccccagaagacactggatttactggtaccaccc
cataagcccgacgagatgacagtggggaaagtgtatgcagctctgatgatattcgacttc
tacaagcagaataaaaccaccagagaccagattcaagctcccgggggcctgtcccagatg
ggccctgtgtccctgttccaccctctgaaggccaccctagagcaaacgcagccagctgtg
ctccgaggagcccgggttttccttcggcagaaaagttccacctccctcagcaatggtgga
gccatacaaacccaagagagtggcatcaaggagtctgtgtcctggggcactcaaaggacg
caggatacaccttgtgaagcctgggcacccctggagcgtggccactcagcagagatccct
gcgatgcagccaggagtactggctgtggatgtccagatgcagaacatggccatgagggcc
cccaatggggacccccaacctggactggagagccagggccgtgctgcctctatgcctcgc
ctggctgcagagactcagcctgtaccagatgccagccccatgaagcgctccatctctaca
ctggcccagcgcccccacgcagcccatctttgcagcactgccctggatcgcccaccccca
agccaggcctcacaccatcaccaccaccgctgccatcggcgcagagacaagaagcagagg
cccttggagaaggggcccagcctgtctgccgacgtggatggtgcaactggcagtgctgca
ggaccagggctgcccccaggagaggggcctgccagctgccggcgggagcgggagcgtagg
caggagcggggtcggtcccaagagcggagacagccatcgtcttcctcctcagagaagcaa
cgcttctactcctgtgaccgttttgggggccgtgagccccccaaacccaagctctccctt
agtagccaccccacgtcaccgacagccggccaggagccaggacctcacccaaagggcagt
ggctcagttaatggcagccccttgccatcagcatctggtgctagcactccaggccgcggt
gggcggaggcagcttccccagacacccccaacgccccgccccagtgtcacctacaagacg
gccaactcttcacccgtgcacttctcgggggcccagaccagccttccggctttctcccct
ggacgactcagccgtggactttctgaacacaacgccttgctgcagacagaccccctcggc
cctccgttggtccccagctctcgaattggctctgacccttacctggggcagcgtctggac
agtgaggcctctgcccacaccctacctgaggacacactcaccttcgaggaggccttggcc
accaactctggccgctcctccaggacttcctatgtgtcctcactgacctcccagtcacac
cccctccgccgggtgcccaatggttaccactgcactctggggctcagctcaggtggccgg
gcccggcacagctaccaccacccagaccaggaccactggtgctag |
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