Otolemur garnettii (small-eared galago): 100959223
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Entry
100959223 CDS
T07855
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
oga
Otolemur garnettii (small-eared galago)
Pathway
oga00270
Cysteine and methionine metabolism
oga00480
Glutathione metabolism
oga01100
Metabolic pathways
oga01240
Biosynthesis of cofactors
oga04216
Ferroptosis
Module
oga_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
oga00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
100959223 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
100959223 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
100959223 (GCLC)
Enzymes [BR:
oga01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
100959223 (GCLC)
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Ortholog
Paralog
GFIT
Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
100959223
NCBI-ProteinID:
XP_003789698
Ensembl:
ENSOGAG00000007018
UniProt:
H0WVF1
LinkDB
All DBs
Position
Unknown
AA seq
637 aa
AA seq
DB search
MGLLSQGSPLSWEDTKRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH
ENKKVQLLLSGGEVLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EANMRKRRKEATSILEENQALCTITSFPRLGCPGFTTPEYKPNPVEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPEDDEAAKASKPDHIYMDA
MGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVI
SASVDDRTREERGLEPLKNNNYRISKSRYDSIDSYLSKCGEKYNDIDLTIDKEIYEQLLQ
EGIDHLLAQHVAHLFIRDPLTLFEEKINLDDANESDHFENIQSTNWQTMRFKPPPPNSDI
GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVL
RGMFYFRKDICKGGNAVVEGCGKAQNSTEPPVEEYALMSIDTIINGKEGVFPGLIPILNS
YLENMEVDVDTRCSILNYLKLIKKRASGELMTVARWMREFIANHPDYKQDSVITDEMNYS
LISKCNQIANELCECPELLGSAFRKVKYSGSKTDSSN
NT seq
1914 nt
NT seq
+upstream
nt +downstream
nt
atggggcttctgtcccagggctcgccgctgagctgggaggacaccaagcgccacgccgac
cacgtgcggcggcacgggatcctccagttcctgcatatctaccacgccgtcaaggaccga
cacaaggacgttctcaagtggggcgacgaggtggagtacatgttggtatcttttgatcat
gaaaataagaaagtgcagttgctcctgtctggaggggaagttcttgagactctacaagag
aagggggaaaggacaaacccaaaccatcctactctctggagaccagagtatgggagttac
atgattgaagggacgcctgggcagccctatggaggaacaatgtctgaattcaacacagtt
gaggccaacatgagaaaacgccggaaggaggccacttctatattagaagaaaatcaggct
ctttgcacaataacttcatttccaagattaggctgtcctgggttcacaacgcctgagtac
aagcccaacccagttgaaggaggagcttccaagtccctgttcttccccgatgaagcaatt
aacaagcaccctcgcttcagtaccctaacaagaaacatccgacacaggagaggagagaag
gtggtcatcaatgtgccaatctttaaggacaagaacacaccatctccatttatagaaaca
tttcctgaggatgacgaggcagcaaaggcttctaagccggatcacatctacatggatgcc
atgggatttgggatgggcaactgctgtcttcaggtgacattccaagcctgcagcatatct
gaggccagatacctttatgatcagttggccactatctgtccaattgtcatggctctgagt
gctgcgtctcctttttaccgaggctatgtgtcagacattgattgtcgctggggagtaatt
tctgcatctgtagatgatcgaactcgggaggagagaggactggagccactgaagaacaat
aactatagaattagtaaatcccgatatgactcaatagacagctacttatctaagtgtggc
gagaaatacaatgacatcgacttgacgatagataaagaaatctacgagcagctgttgcag
gaaggcatcgaccacctcctggcccagcatgttgctcatctctttatcagagaccctctg
actctgtttgaagagaaaataaacctggatgatgccaatgagtctgaccactttgagaat
attcagtcaacaaattggcaaacaatgagatttaagccccctcctccaaactcagatatt
ggctggagagtagaattccgacccatggaggttcagttaacagattttgagaactctgcc
tacgtggtgttcgtggtactgctcaccagagtgatcctttcctacaaattggattttctc
attccgctgtcaaaggttgatgaaaacatgaaagtagcccagaaacgagatgctgtcttg
cgggggatgttttatttcaggaaagatatttgcaaaggtggcaacgccgtggtggagggg
tgtggcaaggcccagaacagcacggagccgcctgtggaggagtacgccctcatgagtata
gacaccatcatcaacgggaaggaaggtgtgtttcccgggctgatcccaattctcaactcc
taccttgaaaacatggaagtggatgtggacaccagatgcagcatcctgaattacctgaag
ctgattaagaagagagcatctggagaactaatgacagttgcccggtggatgagagagttt
atcgcaaaccatcctgactacaaacaagacagtgtaataactgatgaaatgaattacagc
cttatttcgaagtgtaaccaaattgcaaatgagttatgtgaatgcccagagttacttgga
tcagcatttaggaaagtaaaatatagtggaagtaaaactgactcttccaactag
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