Otolemur garnettii (small-eared galago): 100962299
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Entry
100962299 CDS
T07855
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
oga
Otolemur garnettii (small-eared galago)
Pathway
oga04217
Necroptosis
oga04380
Osteoclast differentiation
oga04620
Toll-like receptor signaling pathway
oga04621
NOD-like receptor signaling pathway
oga04630
JAK-STAT signaling pathway
oga04658
Th1 and Th2 cell differentiation
oga04659
Th17 cell differentiation
oga05145
Toxoplasmosis
oga05160
Hepatitis C
oga05161
Hepatitis B
oga05162
Measles
oga05164
Influenza A
oga05165
Human papillomavirus infection
oga05167
Kaposi sarcoma-associated herpesvirus infection
oga05168
Herpes simplex virus 1 infection
oga05169
Epstein-Barr virus infection
oga05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
oga00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
100962299 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
100962299 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
100962299 (TYK2)
04621 NOD-like receptor signaling pathway
100962299 (TYK2)
04658 Th1 and Th2 cell differentiation
100962299 (TYK2)
04659 Th17 cell differentiation
100962299 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
100962299 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
100962299 (TYK2)
05160 Hepatitis C
100962299 (TYK2)
05171 Coronavirus disease - COVID-19
100962299 (TYK2)
05164 Influenza A
100962299 (TYK2)
05162 Measles
100962299 (TYK2)
05168 Herpes simplex virus 1 infection
100962299 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
100962299 (TYK2)
05169 Epstein-Barr virus infection
100962299 (TYK2)
05165 Human papillomavirus infection
100962299 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
100962299 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oga01001
]
100962299 (TYK2)
Enzymes [BR:
oga01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
100962299 (TYK2)
Protein kinases [BR:
oga01001
]
Non-receptor tyrosine kinases
JAK family [OT]
100962299 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kinase-like
Kdo
ABC1
APH
Motif
Other DBs
NCBI-GeneID:
100962299
NCBI-ProteinID:
XP_023373778
Ensembl:
ENSOGAG00000011083
UniProt:
H0X425
LinkDB
All DBs
Position
Unknown
AA seq
1184 aa
AA seq
DB search
MPLCQLGASRGSKPDGTRTQPMAAVGGLKVLLHWAGPGGGDPWVTFTEGSLTAEEICIHI
AHKVGITPPCVNLFALFDSQAQVWLPPNHIIEISRDTSLMLYFRMRFYFRNWHGMNPQEP
AVYRCGPPSTEASSEQTENGVQLLDPASFEYLFEQGKYEFVNDVVSLWELSSEEEIHHFK
NESLGMAFLHLCQLALHHGVSLEEVAKKISFKDCIPCSFRRQIRQHNMLTRLRLRNVFRK
FIKAFQPGVLSQQVVMVKYLATLERLAPRFGTECVPVCHLRLLTQAEVKPYYNLDSKQSP
GDPSPESAAGPSTHEVLVTGTSGIQWRPIQTEDSSGSSGSRGRNPRASRSGKKAKVHEAG
ELPADGQQEPQWAYFCDFRDITHVVLKECHVSIHRQDNKCLDLILPSQAVALSFVSLVDG
YFRLTADSSHYLCHEVAPPRLVMSIQDGIHGPLLEPFVQAKLRPEDGLYLIHWSISHLYR
LILTVAQRSQAPGNTQSLRLRKFPIEQQAGAFVLEGWGCPFTSVQELRAALQGCVLRAGD
DCFSLRRCCLPQPGEISNLIVMRGPQAISRSLNLSQLSFHRVGQDEITQLSHLGQGTRTN
VYEGLLRVEGGDPEEGKVDGRDPPMPCRNCGQELRVVLKVLDPSHHDIALAFYETASLMS
QVSHVHLAFVHGVCVRGSENIMVTEYVEHGPIDVWLRRERGRVPVAWKVVVAQQLASALS
YLEDKNLIHGNVCGRNILLARLGLVEGTSPFIKLSDPGVGLSALSREERVERIPWMAPEC
LPGRTSSLSTATDKWGFGATLLEICFDGEAPLQGRGPSEKERFYQKQHRLPEPSCPELAT
LTSQCLTYDPAQRPSFRTILRDLTRLQPQNLTDILTVNPDFPASDPTVFHKRYLKKIRDL
GEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCSPQLRSGWRREIDILRTLYHEHIVKYK
GCCEDQGEKSVQLVMEYVPLGSLRDYLPRHSVGLAQLLLFAQQICEGMAYLHAQHYIHRD
LAARNVLLDNDRLVKIGDFGLAKAIPEGHEYYCVREDGDSPVFWYAPECLKECKFYYASD
VWSFGVTLYELLTHCDSSQSPPSKFIELIGHTQGQMMVLRLTELLERGDRLPRPDKCPPE
VYLLMKNCWETEASFRPTFQNLIPILKTVQDKYRGQAPSVFNVC
NT seq
3555 nt
NT seq
+upstream
nt +downstream
nt
atgcctctgtgccaactgggggcctccaggggcagcaagcctgatgggacccgaactcag
cccatggctgccgtaggaggcctgaaggtgcttttgcactgggctggccctggtggtggg
gacccctgggtcaccttcactgagggctcgctgactgctgaggaaatctgcatccacata
gcacacaaagttggcatcactcctccctgtgtcaatctctttgccctcttcgattcccag
gcccaagtctggctacccccaaaccatatcatagagatctccagagacacaagcctaatg
ctatatttccgcatgaggttttacttccggaactggcatggaatgaatcctcaggagcca
gctgtgtaccgctgtgggcccccaagcactgaggcttcctcagaacagacagagaatggg
gtgcaactcctagacccagcctcatttgagtacctctttgagcagggcaaatatgagttt
gtgaatgacgtggtatcactgtgggagctgtcaagtgaagaggagatccaccactttaag
aatgagagcctgggcatggcctttctacacctctgccaacttgctcttcaccatggtgtc
tccctggaggaagtggccaagaaaatcagcttcaaggactgcatcccatgctccttccgg
aggcagatcaggcagcacaacatgctgacgcgcttgcgcctgcggaatgtcttccgaaag
ttcattaaggccttccagccgggtgtcctctcccagcaggtggtcatggtcaaatacctg
gccacactcgagcgtctggcaccccgctttggcacggagtgtgtgcccgtgtgccatctg
aggttgctgacccaggctgaagtcaagccctactacaacctggatagcaagcagtcccct
ggggaccctagccctgagtctgctgctgggccctccacccacgaggtgctggttacaggc
accagtggtatccaatggcgacctatacagacagaggactctagtggtagcagtggcagc
cgaggtaggaatccccgtgctagccgatctgggaagaaagccaaggtacacgaggcaggc
gagctgccagcagatggacagcaggagccacagtgggcctacttctgcgacttccgggac
atcacccatgtggtactgaaagagtgccatgtcagcatccatcggcaggacaacaagtgt
ctggacctgatcctgccttcccaggcagtggccctgtccttcgtgtcgctggtggatggg
tatttccgcctaacagctgactccagccattacctgtgtcacgaggtggcccctccacgg
ctggtgatgagcattcaggacggtatccatggccctctgctggagccatttgtgcaagcc
aagctgcggcctgaggatggcctctacctcattcactggagcatcagccatctctaccgc
ctcatcctcacagtggcccagcgtagccaggcccccggcaatacacagagcctgcgcctc
cggaagtttcccattgagcagcaggctggggcatttgtgctggagggctggggctgcccc
ttcaccagtgtacaggagctgcgggctgccttgcagggctgtgtgctgcgggcaggggat
gactgcttctccctgcgccgctgctgtctgccacagccaggagaaatctccaatctcatc
gtcatgcgggggcctcaagccatcagcaggtcactcaacctcagccagctcagcttccac
cgggttggccaggacgagatcacccagctgtctcacttgggccagggcacaaggaccaat
gtgtatgagggcctactgcgagtagagggtggggacccagaggagggcaaagtggatggc
agagaccccccaatgccctgcaggaactgtgggcaggaactacgagtggtgctcaaagta
ttagacccaagtcaccacgacatcgccctggccttctacgagacagccagcctcatgagc
caggtgtcccacgtgcacctggcctttgtgcacggcgtctgtgtgcgtggctctgagaat
atcatggtgactgagtacgtggaacatgggcccatagatgtgtggctgcggcgagagagg
ggtcgtgtgcctgtggcctggaaggtggtggtggcccagcagctggccagcgccctcagc
tacttggaggacaagaacttgattcatggtaatgtgtgtggccggaacatcctgttggca
cggctggggctggtggaaggcaccagccccttcattaagctgagtgacccaggggtgggc
ctgagtgccctctccagggaggagcgggtggagcggatcccctggatggctcctgagtgt
ctccctggcaggaccagcagcctgagcactgccactgacaagtggggctttggtgccacc
ctcctggagatatgctttgatggggaagcccccctccagggccgcggcccctctgagaaa
gagcgtttctaccagaagcagcaccggctgcctgagccctcatgcccagagctggccaca
cttaccagccagtgcctaacctatgatccagcccagaggccatcatttcgcaccattcta
cgtgacctaactcggctgcagccacaaaatctcacagacatcttgactgtgaatccagac
tttccagcgtcagaccccacagttttccacaagcgctacttgaaaaagatccgggatctg
ggtgagggtcattttggcaaggtcagcttgtactgctacgaccctaccaacgatggcact
ggcgagatggtggctgtgaaagccctcaaggcagactgcagcccccagctgcgctcgggg
tggaggcgggagatagacatcctccgcacactctaccatgagcacatcgtcaagtacaag
ggctgctgcgaagaccaaggtgagaagtcggtgcagcttgtcatggaatatgtccccctg
ggcagcctccgagactacctgccccggcacagcgttgggctggcccagctgctgcttttc
gcccagcagatctgtgagggcatggcctacctgcacgctcagcactacatccaccgagac
ttagctgcgcgcaacgtgctgctggacaatgacaggctggtcaagattggggactttggc
ctagccaaggctatacccgaaggccacgaatactactgcgtgcgcgaggatggggacagc
cccgtgttctggtatgccccagagtgcctgaaagagtgtaaattctactatgcttccgac
gtctggtccttcggggtcaccctgtatgagctgctaactcactgcgactccagccaaagt
ccaccctcgaaattcattgagctcataggccacacccaaggccagatgatggtgctaaga
ctcacagagctgctggaacgaggggacaggctgccacggcctgacaaatgcccccctgag
gtctatcttctcatgaagaactgctgggagacagaggcctctttccgcccaacgttccag
aacctcatacccatccttaagaccgtccaggataaataccgaggtcaggccccgtcagtg
ttcaacgtgtgctga
DBGET
integrated database retrieval system
