Otolemur garnettii (small-eared galago): 100965809
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Entry
100965809 CDS
T07855
Symbol
SRD5A2
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 2
KO
K12344
3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:
1.3.1.22
]
Organism
oga
Otolemur garnettii (small-eared galago)
Pathway
oga00140
Steroid hormone biosynthesis
oga01100
Metabolic pathways
oga05215
Prostate cancer
Module
oga_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
oga00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
100965809 (SRD5A2)
09160 Human Diseases
09162 Cancer: specific types
05215 Prostate cancer
100965809 (SRD5A2)
Enzymes [BR:
oga01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
100965809 (SRD5A2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Steroid_dh
DUF1295
Motif
Other DBs
NCBI-GeneID:
100965809
NCBI-ProteinID:
XP_003787557
Ensembl:
ENSOGAG00000000403
UniProt:
H0WGC3
LinkDB
All DBs
Position
Unknown
AA seq
252 aa
AA seq
DB search
MPVRCHQSSVLAGSATLAVMGAVMLVLAEPASYGKHVEMSVRTGLSARAAWFLQELPSFV
VPAGILAQQSRSLFGPPETVLLGLFCAHYFHRTFVYSWLTRGRPLPVFILFKGFVFCMGN
GFLQGYYLIYCAEYPDEWYTDIRFSLGVFLFILGMGINIHSDYILRQLRKPGEVTYRIPQ
GGLFTYVSGANFLGEIIEWIGYALATWSLPALAFAFFTFCFLGLRAFHHHRYYLKMFEDY
PKSRKALIPFIF
NT seq
759 nt
NT seq
+upstream
nt +downstream
nt
atgccggttaggtgccaccagagctcggtgctggcaggtagcgccactttagcggtcatg
ggggcagtgatgctggtccttgcagagcccgccagctacgggaagcacgtcgagatgtcg
gtgcgtaccggcctgtctgcccgcgccgcctggttcctgcaggaactgccctccttcgtg
gtgcccgcggggattctcgcccagcagtcccgctccctcttcggaccgcccgagacggtg
cttctgggtctcttctgcgcgcattacttccacaggacatttgtttactcatggctcacc
agagggaggccgctcccagttttcatccttttcaaaggctttgtcttctgcatgggaaat
ggattccttcaaggctactacctgatttactgtgcagaataccctgatgagtggtacact
gacatacggtttagcttgggtgttttcttatttattttgggaatgggaatcaacattcat
agtgactatatattgcgccagctcaggaagcctggagaagtcacctataggattccacaa
ggtggcttgtttacatatgtttctggagccaatttccttggtgagatcattgaatggatc
ggctatgccctggccacatggtccctcccagcgcttgcatttgcatttttcacattttgt
ttccttgggctgcgggcttttcaccaccacaggtactacctcaagatgtttgaggactac
cccaaatctcggaaagcacttattccattcatcttttga
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