| Entry |
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| Symbol |
SRD5A2
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| Name |
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 2
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| KO |
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| Organism |
oga Otolemur garnettii (small-eared galago)
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| Pathway |
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| Module |
| oga_M00976 | C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone |
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| Brite |
KEGG Orthology (KO) [BR:oga00001]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
100965809 (SRD5A2)
09160 Human Diseases
09162 Cancer: specific types
05215 Prostate cancer
100965809 (SRD5A2)
Enzymes [BR:oga01000]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
100965809 (SRD5A2)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
252 aa
MPVRCHQSSVLAGSATLAVMGAVMLVLAEPASYGKHVEMSVRTGLSARAAWFLQELPSFV
VPAGILAQQSRSLFGPPETVLLGLFCAHYFHRTFVYSWLTRGRPLPVFILFKGFVFCMGN
GFLQGYYLIYCAEYPDEWYTDIRFSLGVFLFILGMGINIHSDYILRQLRKPGEVTYRIPQ
GGLFTYVSGANFLGEIIEWIGYALATWSLPALAFAFFTFCFLGLRAFHHHRYYLKMFEDY
PKSRKALIPFIF |
|---|
| NT seq |
759 nt +upstreamnt +downstreamnt
atgccggttaggtgccaccagagctcggtgctggcaggtagcgccactttagcggtcatg
ggggcagtgatgctggtccttgcagagcccgccagctacgggaagcacgtcgagatgtcg
gtgcgtaccggcctgtctgcccgcgccgcctggttcctgcaggaactgccctccttcgtg
gtgcccgcggggattctcgcccagcagtcccgctccctcttcggaccgcccgagacggtg
cttctgggtctcttctgcgcgcattacttccacaggacatttgtttactcatggctcacc
agagggaggccgctcccagttttcatccttttcaaaggctttgtcttctgcatgggaaat
ggattccttcaaggctactacctgatttactgtgcagaataccctgatgagtggtacact
gacatacggtttagcttgggtgttttcttatttattttgggaatgggaatcaacattcat
agtgactatatattgcgccagctcaggaagcctggagaagtcacctataggattccacaa
ggtggcttgtttacatatgtttctggagccaatttccttggtgagatcattgaatggatc
ggctatgccctggccacatggtccctcccagcgcttgcatttgcatttttcacattttgt
ttccttgggctgcgggcttttcaccaccacaggtactacctcaagatgtttgaggactac
cccaaatctcggaaagcacttattccattcatcttttga |
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