Opisthocomus hoazin (hoatzin): 104326980 Help Entry 104326980         CDS       T08436                                  Symbol RYR3 Name (RefSeq) ryanodine receptor 3   KO K04963   ryanodine receptor 3 Organism oha  Opisthocomus hoazin (hoatzin) Pathway oha04020   Calcium signaling pathway oha04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:oha00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     104326980 (RYR3)    04020 Calcium signaling pathway     104326980 (RYR3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:oha04040]     104326980 (RYR3) Ion channels [BR:oha04040]  Voltage-gated cation channels   Ryanodine receptor    104326980 (RYR3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 MIR SPRY Ins145_P3_rec RIH_assoc Ion_trans EF-hand_1 EF-hand_6 TBK1_ULD Motif Other DBs NCBI-GeneID:  104326980 NCBI-ProteinID:  XP_009930125 LinkDB All DBs Position Unknown AA seq 4839 aa AA seqDB search MFYWDDEVVLQCVASIHKEQRKFCLAAEGLGNRLCFLEPTSEAKYVPPDLCICNFVLEQS LSVRALQEMLTNTGDNASEGAAQGGGHRTLLYGHAVLLRHSFSEMYLTCLTSSRSQTDKL AFDVGLRENAAGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSERYLHLSMSNGSIQV DASFMQTLWNVHPTCSGSNIAEGYLLGGHVVRFFHGHDECLTIPSTDQNDSQHKKVLYET GGAGVRARSLWRVEPLRISWSGSNIRWGQPFRLRHITTGRYLALNEDEGLAMLDREKSDT TSTAFCFRASKELKEKQDSSLKRDIDGMGVPEIKYGDSICFVQHVASALWLTYKAQDAKS ARLGPLKRKVILHQEGHMDDGLTLQRCQNEESQAARIIRNTTSLFSQFISGNNRTLSLTV LPVEEMAQTLQDLITYFQLPEEDLEHEDKQSKLRSLKNRQNLFKEEGMLALVLNCIDRLN DYNSAAHFAGISREEHGTAWKQILNLLYKLLAALIRGNRNNCTQFSSNLDWLISKLDRLE SSSGILEVLHCILIESPEALNIIAEDHIKSIISLLDKHGRNYKVLDVLCSLCVCNGVAVR ANQNLICDNLLPRRDLLLQTRLINDVTSIRPNIFLGVAEGSAQYKKWYFELIIDQVDPFL TAEPTHLRVGWASTSGYAPYPGGGEGWGGNGVGDDLYSYGFDGLHLWSGRVSRAVASVNQ HLLASDDVVSCCLDLGVPSISFRINGQPVQGMFENFGTEGFFFPVVSLSAGVKVRFLLGG RHGEFKFLPPAGYAPCYEALLPKEKMKLEPVKEYKRDSDGVRDLLGTTQFLSQASFIPCP IDTTQIALPFHLEKIRDKLAENIHELWGMNKIELGWTYGKIRDDNKRHHPCLVEFSKLPE TEKNYNLQMSTETLKTLLALGCHIVHAHPAAEEDLKKVKLPKNYMMSNGYKPAPLDLSEV KLLPSQEFLVDRLAENAHNVWAKDRIKQGWTYGIQQDLKNKRNPRLVPYALLDERTKKSN RDSLREAVRTFAGYGYNIEPPDQEIADQTVEKVSIDKIRFFRVEQSYAVKSGKWYFEFEA VTGGDMRVGWARPGCRPDVELGADDQAFVFEGSKGQRWHQGSGFFGRSWQPGDVVGCMIN LDDKSIIFTLNGELLITSKGSELAFADFGIESGFVPICALGLSQIGRMNLGMDASTFKYY TMCGLQEGFEPFAVNMNRDVAMWFSKRLPTFVNVPKNHPHVEIWRIDGTIESPPRLKVTH KTFGTQNSNSDMIYCRLSMPIEFRSSFSFGMGVENASSDAFQKRKHSQEIAAPSTTYFYS LRIFAGQDASSVWVGWVTPDYHFYSENFDLNKNCTVTVTLGDERGRVHESVKRSNCYMVW GGDVIANSQRSGRSNVDLEIGCFVDLATGMLSFTANGKELGTCYQVEPNTKLFPATFVQP TSTNLIQFELGKLKNTMPLSAAIFKSEERNPVPQCPPRLDVQTITPVLWSRMPNSFLKVE TERVSERHGWVVQCLEPLQMMALHIPEENRCVDILELCEQEDLMKFHYHTLKLYSSVSAL GNTRVAYALCSHVDVSQLFYTIDNRYLPGLLRSGFYDLLISIHLEHAKQAKLMMNNEFII PVTDETRTIKLYPDETKKHGLPGVGLSTCLKPGFNFSTPCFIVTSEERQTSSPEIPLDIL KSKAISMLTEAVQCSGTHIRDPVGGQVAFQFVPVLKLIATLLIMGVFDDDNVKQVLLLID PNVFGDHKEETEERTEKEEVTQVEEKAVEAGEKAIRETKAPAKGLLQTRLPESVKLQMCH LLNYFCDCELQHRVEAIVSFADCYVSKLQYNQKYRYNELMQALNMSAALTAKKTKEFRSP PQEQINMLLNFQLGEDCPCPEEIRDELYEFHDDLLIHCGIPLEEEEEEEEDSSLTGKLRS LMYKIKGPPKAEKVEPKEEEEKSPTTLKELISQTMVRWSQEDQIQDPELVRIMYTLLRRQ YDSIGELLQALRKAYTISAASVKDTINLLAALGQIRSLLSVRMGKEEELLMINGLGDIMN NKVFYQHPNLMRVLGMHETVMDVMVNVLGGDKSQIVFPKMVASCCRFLCYFCRISRQNQK AMFEHLSYLLENSSVGLAFPSMRGSTPLDVAAASVMDNNELALALEEPDLDKVVTYLAGC GLQSCPVLLAKGYPDIGWNPIEGERYLSFLRFAVFVNSESVEENASVVVKLLIRRPECFG PDLRGEGGNGLLAAMQEAIRISENPARDLPSQAYKREGDDDEEEIVHMGNAIMSFYSALI DLLGRCAPEMHLIQSGKGEAIRIRSILRSLVPTEDLVGIISIPLKLSTVNKDGTVNEPDM SANFCPDHKAPMVLFLDRVYGIKDQSFLLHLLEVGFLPDLRASASLDTVSLSTTEAALAL NRYICSAVFPLLKRCAPLFSGTEHHASLVDSMLHTIYRLSKGRSLTKAQRDTIEECLLAI CHHLRPSMLQQLLRRLVFDVPLLNEYCKMPLKLLTNHYEQCWKYYCLPSGMGSYGIAVEE ELHLTEKLFWGIFDSLSHKKYDPELFRMALPCLSAIAGALPPDYLDTRIRSTLEKQTSLD PEGNFDPKPVSTANLVLPEKLEYIVSRYAEHSHDKWAFDKTNSGWKYGVSLDENMKTHPL IRPFKTLTEKEKEIYRWPARESLKTMLAMGWSLERTKEGGEATIHQRENEKLRSISQSSQ GNGYSPAPLDLSNVVLSREIQGMVEVMAENYHNIWAKKKKIELESKGGGSHPLLVPYDTL TAKEKSRDREKAQDLFKFLQVNGIIISRGLNEMELDASSMEKRFAFKFLKKILKYIDSAQ EFVAHLEALVTSGKTEKSPHEQEIKFFAKVLLPLVDQYFTNHCLYFLSSPTKTLSSSGYA SNKEKEMVASLFCKLAALVRHRISLFGSDSATMVNCLHILAQSLDTRTVMKSGSELVKAG LRAFFENAAEDLEKTSENLKLGKFTHSRTQIKGVSQNINYTTVALLPILTSIFEHISQYH FGIDLLLGDVQVSCYRILCSLYSLGTGKNIYVERQRPALGECLASLAAAIPVAFLEPSLN HYNPLSVFNTKSARERAILGMPDRVEEMCPEIPQLDGLIKEINNLAESGARYTEMPHVIE VILPMLCNYLSYWWERGSESVPQSAGPCCTMITSEHLSIVLGNILKIINNNLGIDEASWM KRIAVYAQPIISKARPDLLKTHFIPTLEKLKKKAIKIVMEEEQLRADSKADTQEAELLIL DEFAVLCRDLYAFYPILIRYVDNNRSNWLKKPDADSDELFRMVAEVFILWCKSHNFKREE QNFVIQNEINNLAFLTGDTKSKMSKAMQVKSGGQDQERKKSKRRGDLYSIQTSLIVAALK KMLPIGLNMCTPGDQELISLAKTRYSHKDTDDEVKEHLRNNLHLQEKSDDPAVKWQLNLY KDILKSDEPTDPERNVERVQRISAALYHLEQVEQPLRSKKAVWHKLLSKQRKRAVVACFR MAPLYNLPRHRSINLFLHGYQNYWIETEEYSFEEKLVQDLATPPKKDEEEEEETEKKQPD PLHQIILYFSRSALTERSKLEDDPLYIAYSAMMAKSCQEEEEEEEEEEEKDKTFEEKEME KQRTLYQQARLHDRGAAEMVLQMISASKGHTGPMVVETLKLGIAILNGGNTIVQQKMLDY LKEKKDAGFFQSLSGLMQSCSVLDLNAFERQNKAEGLGMVTEEGTLIVRERGEKVLQQDE FTRDLFRFLQLLCEGHNNDFQNYLRTQMGNTTTVNIIISTVDYLLRLQESISDFYWYYSG KDVIDESGQRNFSKALAVTKQIFNSLTEYIQGPCIGNQQSLAHSRLWDAVVGFLHVFANM QMKLSQDSAQIELLKELLDLLKDMVVMLLSLLEGNVVNGTIGKQMVDTLVESSSNVEMIL KFFDMFLKLKDLTNSDAFKEHDPDSKGIISKKEFQKSMEAQKQYNMFNYVDFVERFHEPA KDIGFNVAVLLTNLSEHMPHDSRLQSLLEPAESVLNYFEPYLGRIEIMGGAKKIERVYFE ISESSRMQWEKPQVKESKRQFIFDVVNEGGEQEKMELFVNFCEDTIFEMQLASQISETDS SERPEEEEEAEPSYVVDIEDDEEEEKSLESASAFAMACVAVKKNVANFFKMVTMKNLRKQ YRKVKKMTVKEMVKVFFSFFWILFIGIFQLFFTIVWGIFQILWNTVFGGGLVEGAKNIKV TKLLGDMPDPTQFGIHDDVMEAEKAEGTEHGVGAELVQFVKGEKGETDIFSDIFGIHTKK EGSKHGHDAGLGDIAEILGTDIQSSLENTVRKKKGLQISEIAKEAERERKAEAEKADMED GEKQDKAKEVQSEQLEEGKMKKKKRRHGQKIEKPEAVMANFFKALEIYQTKMLHYLARNF YNLRFLALFVAFAINFILLFYKVTEEPLDEVEEDSNLWNSFDEEEEEEGMVFFVLEESTG YMAPALRALAVIHTIISFVCVIGYYCLKVPLVVFKREKEVARKLEFDGLYITEQPSEDDI KGQWDRLVINTPSFPNNYWDKFVKRKVINKYGDLYGAERIAELLGLDKSALDFSPMEENE PEEASLVSWLSSIDTKYHIWKLGVVFTDNSFLYLAWYTTMSILGHYNNFFFAAHLLDIAM GFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDD MMTCYLFHMYVGVRAGGGIGDEIEDPAGDPYEMYRIVFDITFFFFVIVILLAIIQGLIID AFGELRDQQEQVREDMETKCFICGIGNDYFDTTPHGFETHTLQEHNLANYLFFLMYLINK DETEHTGQESFVWKMYQERCWDFFPAGDCFRKQYEDQLG NT seq 14520 nt NT seq  +upstreamnt  +downstreamnt atgttttactgggatgacgaagtagtacttcagtgtgttgccagtattcacaaagaacaa aggaagttttgcttggcagctgagggacttgggaatcgcctgtgctttttggaaccaaca tcagaagctaaatatgttcctccggacctttgcatctgtaattttgtccttgaacagtcc ctatctgtcagagcccttcaagaaatgctgaccaacacaggtgataatgctagtgaaggg gcagctcaagggggtggtcacagaaccctgctgtatggccacgctgtactactacgacat tcgtttagtgaaatgtatttgacgtgtttaacatcatcaagatcccagactgataaactt gcatttgatgtgggactacgagaaaatgcagcaggtgaggcatgctggtggacgatacac cctgcttctaaacaaaggtcagaaggagaaaaggttcgaataggtgatgatcttatcctg gtcagtgtgtcctctgaaagatacctgcatctctccatgtcaaatggaagtattcaggtg gatgcctcctttatgcagacgctatggaatgtacatcctacatgctcaggaagcaatatt gcagaaggatatcttcttggtgggcatgtagtacgttttttccatggccatgatgagtgt ttgacaattccatctacagatcagaatgattcacagcacaagaaagtactttatgaaact ggaggagctggtgttcgagcaaggtctttgtggagagtagaaccccttcgaataagctgg agtggaagtaatatcagatggggacagcctttccgtcttcgacacattacaacaggaagg tacttggctctgaatgaagatgaaggacttgcaatgttagacagagaaaagtcagacaca acatccactgccttttgttttagagcatcaaaggagctaaaagaaaagcaggattctagt cttaaacgtgacattgatggaatgggcgtcccagaaataaagtacggtgattcgatctgt tttgtccagcatgtggccagtgccttatggttgacttacaaagcacaagatgctaaatca gcacgtttaggtcccttgaaaagaaaggttatattacaccaagaaggccatatggatgat ggtctaaccttacaaagatgtcagaatgaggaatcccaggctgctcgaatcattcgcaac actacaagcttattcagccaatttataagtggaaacaacagaacactatcactcactgtc ctgcctgttgaggagatggctcagactctgcaagacctcattacttacttccagcttccc gaagaagaccttgaacatgaagataagcaaagcaagcttcggtcactcaaaaacagacaa aatctattcaaagaagagggaatgctggcattagttctgaattgcattgatcgcctaaat gactacaacagcgcagctcatttcgcaggaatttcaagagaagaacatggtacagcatgg aaacaaattttgaatctcctttacaaattgttagctgctctcattcgtggcaacagaaac aattgtactcagttttccagtaacctcgattggctaataagcaaattggacagattagaa tcttcctcaggtattctggaagtgttgcactgcatcttgattgaaagcccagaagcttta aatataatagctgaggaccacatcaaatccattatttcattgttggataaacatgggcgt aattacaaggttctcgacgtgctttgctctctctgtgtctgtaatggagttgcagttcgt gccaatcaaaatctgatctgtgacaatctactccctagaagagatttactcttgcaaaca cgtttgattaatgatgtgacaagcataaggccaaacatatttttgggtgttgcggagggc tctgcacaatacaagaagtggtacttcgagttaataattgaccaagttgatccattcttg acggcagaacccacccatttacgagttggatgggcttctacttcaggttatgccccctat cctggaggtggggaaggatggggaggcaatggtgttggtgatgacctgtactcttatggt tttgatggtcttcatctgtggtctggtcgagtatcccgagctgtagcatctgtcaatcag catttattagcatctgatgatgtggttagctgctgcttggatttaggtgtacccagcatt tcattccgcattaatggacagcctgtgcaaggaatgtttgagaacttcggtacagaaggg tttttcttccctgttgtaagcttatcagcaggtgtaaaggttcgcttcttattgggtgga cgtcatggagagtttaaatttctacctcctgctggctatgctccctgttatgaagcgttg cttccaaaagagaagatgaaactggaaccagtgaaagaatataagagagattctgatgga gtgagggatttgctgggtacaacacaattcctgtcccaagcttcctttatcccttgtcca atagacaccactcagattgctcttccttttcatcttgaaaagatcagggacaagctagct gaaaatatccatgaactgtggggaatgaataaaatagaactgggctggacgtatggcaag atacgggatgataataaaaggcatcatccttgtcttgtggaattctcaaaattacctgag acagagaagaattataatctacaaatgtcaactgaaaccctcaaaacccttttggccctt ggatgccacattgttcatgctcacccagccgctgaggaagatcttaaaaaagtcaaactt cctaaaaattacatgatgtcaaatggatataaacctgcccctcttgatctttctgaagtg aaattgttaccttctcaagaatttctagttgacagactagcagaaaatgcacataatgtc tgggcaaaagacagaataaagcaaggatggacctatggcattcaacaggatcttaagaac aaacgtaatcctcggctagtgccatatgcattattagatgaacgtactaaaaaatcaaac agagatagcctccgtgaagctgttagaacatttgcgggctatggttataatattgagcca cctgaccaagagatagctgaccaaacagtggaaaaagtcagcattgacaagatacgattt ttcagagtagaacagtcttatgcagtgaagtctggaaagtggtactttgaatttgaagct gtgacgggtggagatatgcgtgttggctgggccaggccaggctgtcgacctgacgtagag ttgggagctgatgaccaagcatttgtattcgaaggaagcaaaggccagcgttggcatcaa ggcagtggattctttggacgaagctggcaaccaggagacgtggttggttgtatgataaac ttggatgacaaatcaattatctttactctgaatggagagctgctcataaccagtaaaggt tcagaactcgcatttgctgactttggaatagaaagtggttttgttccgatttgtgcactg ggtctatctcagattggtcgtatgaaccttggaatggatgccagtacattcaaatattat acaatgtgtggccttcaagaaggttttgaaccttttgctgtcaacatgaaccgggatgtt gctatgtggtttagcaaacgcttaccaacatttgtcaatgtgccaaaaaatcatcctcac gttgagatatggagaattgatggaactattgagagtccacctcggttaaaagttactcac aaaacattcggcacacagaacagcaattcagacatgatatattgtcgtttgagtatgccc attgagttccgctcatctttcagctttggcatgggtgtggaaaatgcctcatctgatgct ttccaaaaacgaaagcacagccaagaaattgctgctccttctactacatatttttattca ctacggatatttgctggccaagacgcgtcctctgtctgggttggttgggtaacaccagac tatcatttttatagtgagaattttgacctaaataaaaattgtacggtgacagttacttta ggtgatgaaagaggcagggttcatgaaagtgtgaagcgtagcaattgctatatggtttgg ggaggagatgtaattgctaattcccagagatcaggtcgcagtaatgttgatttagaaatt ggatgctttgttgacctggctactggaatgttgtcattcacagccaatggaaaagagctt ggcacttgctaccaggttgaaccaaacacaaaactttttccagcaacttttgtacagcct acaagcactaacttgattcagtttgaacttggtaaattaaagaataccatgcctttatca gcagcaatttttaaaagtgaagaaagaaatcctgttcctcagtgtcctcctcgccttgat gtgcaaaccattacacctgttttatggagcaggatgccaaacagctttctaaaagtagaa actgagcgtgtcagtgaacgtcatggctgggttgtgcaatgtttggagcctctgcagatg atggcacttcatatcccagaggaaaacagatgcgttgatattttggaactatgtgaacaa gaagatttgatgaagtttcactaccacactttaaaactctatagctcagttagtgctcta ggtaacactagagttgcttatgcactttgtagccatgtggatgtatctcagctattttat actatagataatcgatacttacctggactcctacgttctggattctatgacttgctgatt agtattcatttggagcatgccaagcaagccaagctcatgatgaacaatgaatttatcatt ccggttacagatgaaactcgaactattaaattatatcctgatgaaacaaagaagcatggt ttacctggagtagggcttagcacttgcctgaaaccaggctttaatttttctactccatgc tttattgtgaccagtgaagaacgacagacatccagcccagagataccccttgatatactt aaatccaaggccataagtatgctaacagaggcagtacagtgtagtggtactcatatacga gaccctgttggaggacaggttgcgttccagttcgttcctgttcttaaacttatagcaaca ttgctcataatgggggtttttgatgatgataatgtgaagcaggtgttactcctcatcgac cccaacgtgtttggagatcacaaggaagaaacagaagagaggacagagaaggaagaagtt acacaagttgaagaaaaagctgtagaagctggggaaaaagcaataagagaaacaaaagct cctgcaaagggcttattgcagacaagattaccagaatctgttaagcttcagatgtgccat ttactcaattatttctgtgactgtgagctgcaacatagagtggaagcaattgtatcattt gcagactgttatgtatcaaaattgcaatataatcagaaatacaggtacaatgaactcatg caagccttgaacatgtctgctgctttgactgccaagaagactaaagaatttcgttctcct cctcaagaacagattaatatgttgctgaattttcaactgggagaggattgtccctgtcca gaggagattcgagatgagttgtatgaatttcatgatgatcttctaattcactgtggtatt ccactagaagaggaggaagaggaagaggaagattcctccttgactggcaaactccgttca ttaatgtacaaaatcaaaggtccgccaaaagcagaaaaagtagaacctaaggaggaagaa gagaaatctcctactacactgaaagaactcatatcccagactatggtacgctggtcccag gaagatcaaattcaagatcccgaattagttcggattatgtacaccctccttcgtaggcaa tatgacagcattggtgagctactgcaagctctgaggaaagcatacaccattagtgctgcc tctgtgaaggataccattaatctgcttgcagcactgggccagattcgctcacttctcagt gtcaggatgggaaaagaggaggaattgctaatgattaatggattaggggatataatgaac aacaaggtgttttatcagcatcctaacttaatgagagtcttgggcatgcatgagactgtc atggatgtgatggtgaatgtgcttggaggagataaatctcagatcgtttttcctaagatg gtggcaagctgttgcagattcctgtgctacttctgtcgaattagtcgtcaaaaccaaaag gccatgtttgagcatctaagttacttactggaaaacagcagcgttggactggcatttcct tcaatgagaggttcaacaccgctagatgttgcagcagcctctgtaatggacaataatgag cttgcactagcgttggaggaaccagatcttgataaggttgttacctacctggcaggttgt ggcctgcagagttgtccagtgttgctggctaaaggatatccagacattggatggaatcca atagagggtgaacgttacctgtcattcttaagatttgcagtttttgttaacagtgaaagt gttgaggaaaacgcaagtgttgttgtcaagctccttattcgacggccggagtgctttgga ccagaccttaggggagaaggaggaaatggtttgctggcagctatgcaggaagctatcagg atctcagagaatcctgctcgtgaccttccctcccaggcttataaaagagaaggtgatgac gatgaggaggagattgtacacatgggcaatgcaatcatgtcattttactcagctctcata gatttacttggacgctgtgcaccagaaatgcatcttattcaaagtggaaaaggggaagct attcgaatcaggtcaatccttcgatctctagtgccaactgaagatttggttgggattata agtataccactaaagctgtcaacagtcaacaaagatggcacagtaaatgagccagacatg tctgcaaatttctgtcctgatcataaagcacccatggtactcttcttggaccgcgtctat ggtattaaggaccaaagcttcctccttcacctactggaagttggatttttaccagattta agagcctctgcctccttggatacagtttctctgagtaccacagaggcagctctcgcacta aatagatatatttgctcagctgtgtttccattactcaaaagatgtgctcccctcttttcc ggaacagagcatcacgcctctcttgttgactccatgcttcacacaatatataggttatcg aagggacgttcccttacaaaagcacaaagggatactattgaagaatgcctgcttgctatt tgccaccacttacggccctctatgttacagcagctgttgagaaggctggtttttgacgtg cctctactcaatgaatactgtaaaatgcctctcaagcttctgacaaatcactatgagcag tgctggaaatattattgtctgccttcaggaatgggaagctatggaattgcagtggaagaa gaattacatttaactgaaaaacttttctggggaatatttgattccttgtctcataagaag tatgatccagagctctttcgaatggctttgccttgtctaagtgctatagctggtgccttg ccacctgattatttagatacacgaattaggtcaactttggaaaagcagacttcactggat ccagaaggaaattttgatccgaaacctgtcagcacagcaaaccttgtacttcctgaaaag ttggagtatattgtcagcaggtatgctgaacattcgcatgacaaatgggcctttgataag actaatagtggatggaaatatggtgtttcactggatgaaaacatgaagactcacccatta ataagacctttcaaaactttaactgaaaaggaaaaggaaatttatcgttggcctgccaga gaatcactgaaaaccatgttggccatggggtggagcctagaaagaaccaaggaaggagga gaagcaacaatacatcagcgtgaaaatgaaaagctccgcagcatatctcagtctagtcag ggaaatgggtatagtccagcaccacttgatctttctaatgtggtgctttctagggagatt cagggaatggttgaagtaatggcagaaaactatcataatatatgggccaaaaagaagaaa atagagttggaaagcaaaggtggaggtagtcatcctttactggtaccttatgacacattg acagccaaggagaagtcacgggaccgtgaaaaggcacaagacctgtttaaattccttcaa gtcaatggtataatcatatctcggggtctgaatgagatggagttggatgcttcatctatg gaaaagagatttgcctttaagtttctaaagaaaattttaaaatacattgattctgctcaa gagtttgttgcgcatttggaagcccttgtaaccagtggaaaaactgaaaaatctccacat gagcaagaaataaaattttttgccaaagttcttttaccattagttgatcagtactttaca aatcactgcctctacttcctgtcttctccaacaaaaacactcagtagcagtggatatgct tcaaataaggaaaaggaaatggtagcaagcctgttctgcaaactagctgctcttgttaga cataggatctcactttttggtagtgattctgctacaatggtgaactgcctgcacatctta gctcagtctcttgacacacgaactgttatgaaatcaggatctgagcttgttaaagctgga ttgcgtgccttttttgaaaatgcagctgaagacctggaaaaaacttcagaaaatcttaaa cttggaaaatttacccattcacgaactcaaatcaagggtgtttcacagaatatcaattat actacagtagcattgttaccaatcttgacatcgatttttgaacatatttcacaatatcat tttggaattgatttactcttgggtgatgtacaagtttcatgttacagaattctttgtagc ctctattcccttgggactgggaagaacatctatgttgaaaggcagcgtcctgcacttggt gagtgcttagcatctcttgcagcagccattcccgtagcattcctcgaaccttctctcaac cattacaacccattgtcagttttcaacacaaaaagtgcaagagaaagagcgattttaggt atgcctgacagagtagaagagatgtgtccagagatccctcagttggatggactaataaaa gaaattaacaatttagcagagtctggagcaaggtatactgaaatgcctcatgtaattgag gttatcttacccatgctatgcaactatttatcctactggtgggaaagaggatctgagagt gttcctcaaagtgctgggccttgctgtacaatgataacatctgagcatctgagcatcgtt cttggaaacattctaaaaatcattaacaacaatctgggaatagatgaagcatcttggatg aaaagaattgcagtttatgctcaacccatcatcagcaaagccaggcctgatctgctcaaa actcactttattccaacattggagaaactgaagaagaaagctataaagattgtgatggaa gaggagcaactgagagcagatagtaaagctgacacccaagaagctgagctactcattctc gatgagtttgctgttctttgtagagacctttatgccttctatccaatattgatacgttac gtagacaacaacagatccaattggctaaagaaaccagatgcagattctgatgaactcttt cgaatggtagctgaagtttttatcctgtggtgtaaatcacataatttcaaaagagaagaa cagaattttgtgattcaaaatgaaatcaacaatttggcatttttaactggtgacaccaag agcaagatgtctaaagccatgcaagtaaagtctggaggacaagatcaagagagaaagaaa tcaaaacgtagaggggatttgtactccatacaaacatccttgattgtagctgcacttaaa aagatgcttcctattggtctgaatatgtgtactcctggggatcaagagctcatctctttg gctaagacgagatacagccataaggacactgatgatgaagtcaaagaacatttacgtaac aacttacatttgcaggaaaagtctgatgatccagctgtgaaatggcagttaaatctgtac aaagacattctgaagagtgatgaacctactgaccccgagagaaatgtggagcgtgtgcag aggatatcagctgctctctatcatctggaacaggttgaacaaccactgagatcaaagaaa gctgtttggcacaaactcctgtcaaaacaacgcaaaagggctgttgttgcgtgtttcaga atggcaccgttatacaacctgcctaggcaccgttctattaacctcttcctccatggctat cagaactattggatagaaacagaggaatattcatttgaggagaaactagttcaggatttg gctacacctccaaaaaaagatgaagaggaagaggaagagactgagaaaaaacagcctgat ccacttcatcagattatcctctatttcagtcgcagtgctctcacagaaagaagcaaacta gaagatgatcctttatatattgcctattcggccatgatggcaaagagctgtcaggaagaa gaagaagaagaagaggaagaagaagaaaaagataagacatttgaggagaaagaaatggaa aaacagcgaactctctatcagcaagctcgcttacatgatcgtggagctgctgagatggtc cttcagatgattagtgcaagcaaaggtcatacaggacccatggtggttgaaacactaaaa cttggtattgctattctaaatggtgggaataccatagttcaacagaaaatgctagactac ctgaaggagaaaaaggatgctggattttttcaaagtctctctggcttgatgcagtcctgc agcgttcttgacttgaatgcgtttgagagacaaaataaagcagaaggcctgggaatggtt actgaagaaggaactctcatcgttcgtgagcgtggtgaaaaagtgttgcagcaggatgaa tttactcgagatctgtttaggtttttacagctgctatgtgaagggcataacaatgatttt caaaattacctacgtactcagatgggcaacaccactacagtgaatattatcattagtaca gttgactatctcttgcgtcttcaggaatcaatcagtgacttctattggtactattcagga aaggatgtcattgatgaatcaggacaacgtaacttttctaaagctctggctgtcaccaaa caaatattcaattcccttacagaatatatacagggcccttgcataggtaatcaacagagt ctggctcatagcaggctgtgggatgcagttgttggctttcttcatgtttttgccaatatg cagatgaaactttcacaggactctgctcagattgaattgcttaaagaactgctagatctg ctaaaggatatggtagtgatgctcttgtcactgcttgaaggtaacgttgtaaatggaact attggaaaacaaatggtagacacacttgtcgaatcatctagcaatgtagaaatgattttg aagttctttgacatgttcctcaagttaaaagatctgactaactcagatgctttcaaagag catgacccagatagtaaaggcatcatttcaaagaaggagtttcagaaatcaatggaggct caaaaacaatacaatatgtttaactacgttgattttgtggaaagattccatgaaccagcc aaagacattggatttaacgtagcagtattgctaacaaacctttcagagcacatgcctcat gattcacgccttcagagcttacttgaacctgcggagagtgttcttaattactttgaacca taccttggccgtattgaaataatgggtggagccaagaaaatagaaagagtttactttgaa atcagtgaatccagtcgaatgcagtgggagaagccacaggtgaaggaatccaaaaggcag ttcatattcgatgttgtaaatgaaggtggagagcaagaaaaaatggaactctttgtcaat ttctgtgaagacacaatctttgaaatgcagttagcatcccagatctctgaaacggattca tctgagaggcctgaggaagaggaagaggcagagccttcttatgtagtggatattgaagat gatgaggaagaggaaaagtccctggaatctgcttcagcttttgcaatggcctgtgttgca gtgaagaagaatgttgccaacttttttaaaatggtcactatgaagaacctaaggaaacaa tacaggaaagttaaaaagatgacagtaaaagagatggtgaaagtgtttttctcctttttc tggatcctatttatagggatattccaactgttctttactatagtgtggggaattttccag attctttggaacactgtgtttgggggtggcctggttgaaggagccaaaaacattaaagtt actaaactattaggggacatgcctgacccaacacagtttggaatccatgatgatgttatg gaagcagaaaaagctgaaggcactgagcatggtgtcggagctgaacttgtgcagtttgtg aagggtgaaaagggagaaactgacatcttctcggacatttttggcattcatacaaagaaa gaaggctcaaaacacggtcatgatgctggactaggagatattgcagaaatccttggtact gatatccagtcgtctttggaaaacacagttcgtaagaagaaagggttacagatatctgaa attgcaaaagaagctgaaagagaaagaaaagcagaagctgagaaggcagacatggaagat ggggagaaacaagataaagcaaaggaagtacaatccgagcagctagaagagggaaaaatg aagaaaaagaagcgaaggcatggacaaaaaattgagaaaccggaggctgttatggctaac ttcttcaaagctttggaaatttatcaaacaaaaatgcttcactacttggcaagaaatttt tataacttaaggtttcttgctctatttgttgcatttgccatcaattttattcttctgttt tacaaggtgacagaagagccacttgatgaagtagaggaagactctaatctctggaactct ttcgatgaagaggaagaggaggagggcatggtgttttttgttttagaagaaagtacaggt tacatggcacctgctctcagagcattggcagttattcacacgatcatctcctttgtctgt gtgattggatactactgcttaaaggtccctctggttgtattcaagagagaaaaggaggta gctagaaagctggaatttgatggactatacataactgaacagccatctgaagatgatatt aaaggccaatgggatcgcctggttatcaatactccgtcctttcctaacaactactgggac aaatttgtaaaacggaaggttattaacaagtacggagacttatatggagcagagcgcata gcagaacttttgggtttggacaaaagtgcccttgattttagtccaatggaagagaacgaa ccagaagaggcgtctcttgtatcatggttaagctccattgacacaaagtaccacatttgg aagctcggagtagttttcactgataattcgtttttatacttagcttggtacacgactatg tccatccttgggcactacaacaacttcttctttgctgctcatctgctggacattgcaatg ggtttcaagacattgcgaaccattttgtcttcagtcacgcacaatggcaaacagcttgtg cttactgtaggactcctcgccgtagtagtatatctttacactgttgtggcgttcaacttc ttccgcaaattctacaacaaaagtgaagatgaagatgaaccagacatgaaatgtgatgac atgatgacgtgttacctgttccacatgtatgtgggtgtaagagctggtggtggcattggg gatgaaattgaggatcctgctggagacccttatgaaatgtatcgaattgtctttgacatc acttttttcttctttgtcattgttatcctgctggccattattcaaggtctgattattgat gcttttggtgaattgagagaccagcaagaacaagtgagagaagatatggagaccaaatgt tttatttgtggaatcggcaatgactattttgacacaaccccacatggctttgaaacacat actttgcaagaacacaacttggcaaactatctgttctttttaatgtatctcattaacaag gatgaaactgagcatactggccaggagtcatttgtgtggaagatgtaccaagaaagatgt tgggattttttcccagcaggggactgcttccggaaacagtacgaggatcaacttggttaa

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