Opisthocomus hoazin (hoatzin): 104335977 Help Entry 104335977         CDS       T08436                                  Symbol UBR4 Name (RefSeq) E3 ubiquitin-protein ligase UBR4   KO K10691   E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27] Organism oha  Opisthocomus hoazin (hoatzin) Brite KEGG Orthology (KO) [BR:oha00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:oha04121]     104335977 (UBR4) Enzymes [BR:oha01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      104335977 (UBR4) Ubiquitin system [BR:oha04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    UBR box proteins     104335977 (UBR4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  E3_UBR4_N E3_UbLigase_R4 UBR4 zf-UBR Motif Other DBs NCBI-GeneID:  104335977 NCBI-ProteinID:  XP_009940081 LinkDB All DBs Position Unknown AA seq 5179 aa AA seqDB search MVSSSSSHPASAGTVVCGGAKGTRGFVLPYSAAVLGIAKREKSSSEFGAADAVCSLPPLQ IESEILHHDKQYEPFYSSFVALSTHYITTVCGLIPRNQLQSVAAACAVLIEFSLLRLENP DEACAVSQKHLILLIKGLCTGCSRLDRTEIITFTAMMKSAKLPQTVKTLSDVEDQKELAS PVSPELRQKEVQMNFLNQLTSVFNPRVSSSPSVPPETQVEAESEDQASTDQTSAAKTKSI FIAQNVASLQELGGSEKLLRVCLNLPYFLRYINRFQDAVSANSFFIMPATVADATAVRNG FHSLVIDVTMALDTLSLPVLEPLTPTRLQDVTVLALSCLYAGVSVATCMAILHVGSTQQV RTGSTSSKEEDYENDAATIVQKCLEIYEMIGQAISNSRRAGGEHYQNFQLLGAWCLLNSL FLILNLSPTALADKGKEKDPLAALRVRDIIARTKEAAGSPKLGPGKGHQGFGVLSVVLAN HAIKLLSSLFQDLQVEALHKGWESDGPPAVLDIMAQSTSIQRIQRLIDSVPLTNLLLTLL STSYRKACVLQRQRKGSVSSDASASTDSNTYYEDDFSSTEEDSSQDDDSEPILGQWFEET ISPSKEKVAPPPPPPPPPLESSPRVKSPNKQAAGENGNILASRKDPELFLSLASNILNFI TSSMLNSRNNFIRNYLSVSLSEQHMATLASIIKEVDKDGLKGTSDEEFAAALYHFSHSLV TSDLQSPALQNTLLQQLGVAPFSEGPWPLYIHPQSLSVLSRLLLIWQHKATAQGDPDVPE CLKIWERFVGTLKQNALQGTLPSDTEDLNVEHLQLLLLIFHNFSERGRRSIMMLCIQTIV ELTVNMDTQQCSVPLIVARLLLVFDYLLHQYSKAPMYLFEQVQYNLLTPPIGWVSGSQDS SRQTSVPLYHGFKEVEENWTKHCSSDAVPQPRFYSILSLEASEDDMNRLDSTVCEVLFSR TVKYDELYTALTSLLAAGSQFDTLRRKENKNVTALEACALQYYFLILWRILGILPPSKSY MNQLAMNTPEMSECDILHTLRWSSRLRITSYVTWIKDHLTKQGMKADHAASLIELASSKC SSVKYDVEIAEEYFARQISSFCAVDCTTILQLHEVPSLQSIYTLDAAISKIQVSLDEHFS KLAAETDPHKSSEITKNLLPATLQLIDTYATFTRSYLLRSLSEEGSTENKPSEEKLRGYA AVLAIGSSRCKSNTLGPTLVQNLPSAVQTLCESWNNIHTNEFPNIGSWRNAFANDTIPAE SYISAVQAAHLGTLCSQSLPLAASLKHTLLSLVRLTGDLIVWSDDLNLPQVIHSLLPLLL ETSTESVAEISSNSLERILGPAESDEFLARVYEKLITGCYSILAHHSDPNSGLDESVLEE CLQHLEKQLESSQARKAMEEFFSESGELVQIMMATANENLSAKFCNRVLKFFTKLFQLTE KSPNPSLLRLCGSLAQLACVEPVRLQAWLTRMTMSPPKDSDQLDVVQENRQLLQLLTTYI VRENSQVGEGVCTVLLSTLIPMAAEMLANGDGTGFPELMVVMATLASAGQGAGHLQLHGA AVDWLGRCKKYLSQKNVVEKMNANVMQGKHVTILECTCHIVSYLADVTNALSQTSGQGPS HLSVDGEERAIEVDSDWVEELAVEEEDSQAEDSDEDSLCNKLCTFTITQKEFMNQHWYHC HTCKMVDGVGVCTVCAKVCHKDHEISYAKYGSFFCDCGAKEDGSCLALVKRTPSSGMSST MKESAFQSEPRVPESVIRHASTSPAEKAKVTISEGKGTDEEKPKKSSLCRNVEGCREELQ SQANFSFAPLVLEMLNFLMDAIQINFQQASAMGSSSRAQQALNELHTLDKSVEMTDQLMV PTLGSQEGAFENVRMNYSGDQGQTIRQLISAHVLRRVAMCVLSSPHGRRQHLAVSHEKGK ITVLQLSALLKQADSSKRKLTLTRLASAPVPFTVLSLTGNPCKEDYLAVCGLKDCHVLTF SSSGSVSDHLVLHPQLATGNFIIKAVWLPGSQTELAIVTADFVKIYDLSVDALSPTFYFL LPSSKIRDVTFLFNEEGKNIIVIMSSAGYIYTQLMEEASSAQHGPFYVTNVLEVNHEDLK DSNGQVAGGGVSVYYSHVLQMLFFSYCQGKSFAATISRANLEVQRLFPINIKSSNGGSKT SPALCQWSEVMNHPGLVCCVQQTMGVPLVVMVKPDTFLIQEIKTLPAKAKIQDMVAIRHT ACNEQQRTTMILLCEDGSLRIYMANVENTSYWLQPSLQPSSVISIMKPVRKRKAAAITTR TSSQVNFPIDFFEHNQQLTDVEFGGNDLLQVYNAQQIKHRLNSTGMYVANTKPGGFTIEV TNNNSTMVMTGMRIQIGTQAIERAPSYLEIFGRTMQLNMTRARWFDFPFTREEALQADKK LTIFIGASVDPAGVTMMDSIKIYGKTKEQFGWPDEPPEDFPSASVSNVCPPNLNQGNGTG DTELATPAAASGTVLERLVVSSLEALESCFAVGPVNEKEKSKVAAQELATMLLSMPAPSS VQQQTKSLLASLHTSRSAYHNHKDQALLSKAIQYLSSSTKEGKDLDPEIFQRLVITARSI AIMRPNNLVHYTESKLPQLETESEEGQEAQKHAEGDGCTFIIQLVNHFWKLHASKPKNAF LAPACLPGLTHVEATVNALVDIIHGYCTCELDCIHTASKIYMQMLLCPDPAVSFSCKQAL IRVLRPRNKRRHVTLPSSPRSNTPMGDKDDDDDDDAEDKLQSSGIANGEHIRQESQEQSE VDHGDFEMVSESMVLETSENVNNGNPSPLEALLAGAEGFPPMLDIPPDADDETMVELAIA LSLQQDQQGSSSSALGLQSLGLSGQAPSSSSLDAGTLSDTTASAPASDDEGSTAATDGST LRTSPADHGGSVGSESGGSAVDSVAGEHSVSGRSSAYGDTTAEGHPVGPGSISSSTGAIS TTTGQQEGDGSEGEGEAEGDVHTSNRLHMVRLMLLERLLQNLPQLRNVGGVRAIPYMQVI LMLTTDLDGDDEKDKGALDNLLSQLIAELCMDKKDVSKKNERSAVNEVHLVVMRLLSVFM SRTKSGSKSSICESSSLISSATAAALLSSGAVDYCLHVLKSLLEYWKSQQNDEEPVATSQ LLKPHTTSSPPDMSPFFLRQYVKGHAADVFEAYTQLLTEMVLRLPYQIKKIADTNSRIPP PIFDHSWFYFLSEYLMIQQTPFVRRQVRKLLLFICGSKDKYRQLRDLHTLDSHVRGIKKL LEEQGIFLRASVVTASSGSALQYDTLISLMEHLKACAEIATQRTVNWQKFCIKDDSVLYF LLQVSFLVDEGVSPVLLQLLSCALCGSKVLSVASSSGSSSTSSTSAAAASGSVQPATQSK SSTKKSKKEEKEKEREGESLGSQEDQLCTALVNQLNKFADKETLIQFLRCFLLESNSSSV RWQAHCLALHIYRNSNKSKQVLLLDLMWSIWPELPAYGRKAAQFVDLLGYFSLKTQQTEK KLKEYSQKAVEILRTQNHILTNHPNSNIYNTLSGLVEFDGYYLESDPCLVCNNPEVPFCY IKLSSIKVDTRYTTTQQVVKLIGSHTISKVTVKIGDLKRTKMVRTINLYYNNRTVQAIVE LKNKPARWHKAKKVQLTPGQTEVKIDLQLPIVASNLMIEFADFYENYQASTETLQCPRCS ASVPANPGVCGNCGENVYQCHKCRSINYDEKDPFLCNACGFCKYARFDFMLYAKPCCAVD PIENEEDRKKAVTNINTLLDKADRVYHQLMGHQPQLENLLCKVNEAAPEKPQDESGSSGG ISSTSASVNRYILQLAQEYCGDCKNSFDELSKIIQKVFASRKELLEYDLQQREAATKSSR TTAQPTFTASQYRALSVLGCGHTSSTKCYGCASAVTEHCITLLRALATNSAIRHILVSQG LIRELFDYNLRRGAATMREEVHQLMCLLTRDNPEATQQMNDLIIGKVSAALKGHWANPDL ASSLQCEMLLLTDSISKEDSCWELRLRCALSLFLMAVNIKTPVVVENITLMCLRILEKLI KPPAPTSKKNKDVPVDALTTVKPYSNEIHAQAQLWLKRDPKASYEAWKKCLPARGVDAKG KSLSKAELHQLYLSEKYVWKWKQFMSRRGKRTCPLDLKLGHNNWLRQVLFTPATQAARQA ACTIVEALATIPSRKQQILDLLTSYLDELSIAGECAAEYLALYQKLIKPAHWKVYLAARG VLPYVGNLITKEIARLLALEEATLNTDLQQGYALKSLTGLLSSFVEVESIKRHFKSRLVG TVLNGYLCLRKLVVQRTKLIDETQDMLLEMLEDMTTGTESETKAFMAVCIETAKRYSLDD YRTPVFIFERLCSIIYPEENEVTEFFVTLEKDPQQEDFLQGRMPGNPYSSNEPGIGPLMR DVKNKICQDCDLVALLEDDSGMELLVNNKIISLDLPVAEVYKKVWCPTNEGEPMRIIYRM RGLLGDATEEFIESLDSTTDEEEDEEEVYKMAGVMAQCGGLECMLNRLTGIKDFKQGRHL LTVLLKLFSYCVKVKINRQQLVKPEMNTLNVMLGTLNLALVAEQESKDSGGAAVAEQVLS IMEIILDESNAEPLSEDKGNLLLTGDKDQLVMLLDQINSTFVRSNLSVLQGLLRIIPYLS FGEMEKMQILVDRFKPYCNFDKYDEEHSGDDKVFLDCFCKIAAGIKNNSNGHQLKDLILQ KGITQNALDYMKKHIPSAKNLDADIWKKFLSRPALPFILRLLRGLATQHPATQVLIGTDS ITNLHKLEQVSSDEGIGTLAENLLEALREHPEVNKKIDAARKETRAEKKRMAMAMRQKAL GTLGMTTNEKGQVVTKTALLKQMEELIEEPGLTCCICREGYKFQPTKVLGIYTFTKRVAL EEFENKPRKQQGYSTVSHFNIVHYDCHLAAVRLARGREEWESAALQNANTKCNGLLPVWG PHVPESAFATCLARHNTYLQECTGQREPTYQLNVHDIKLLFLRFAMEQSFSVDTGGGGRE SNIHLIPYIIHTVLYVLNTTRATSREEKNLQSFMEHPKEKWVESAYEVDGPHYYTVLALH ISPPEKWKAMRVEILRRLLVTSHARVVSPGGASRLADKAVKEYAMYRSGLLFWALVDLIY NMFKKVPTSNTEGGWSYSLAEFIRHNDMPIHEAADKALKTFQEEFMPVETFSEFLDVAGL LSEIGDPDSFLKDLLNSIP NT seq 15540 nt NT seq  +upstreamnt  +downstreamnt atggtctcctcttcgtcctcccaccctgccagtgctggcaccgtcgtgtgcggcggggcg aaggggacgcgtgggttcgttttgccgtactctgcagcagtgcttggcattgccaaacgt gagaaatcatcgtctgagtttggtgcagctgatgcggtctgctccctgcctcccctccag attgaatccgaaatcctgcaccatgacaaacagtatgagcctttttactcttccttcgtt gcgctttccacgcattacatcactactgtctgtggtctaataccaagaaatcaattgcaa tcagtggcagctgcttgtgcagtcctgattgaattctcgctgctgcgtctggagaacccg gatgaggcgtgcgctgtttcgcagaagcacctcattttactgataaagggactgtgcacg ggctgcagccgcctagatcgaactgaaattattaccttcacagcaatgatgaaatcggcc aagctgcctcagactgtgaaaaccctctctgatgtagaggaccagaaggagctggcctcc ccggtgagcccagaactaaggcagaaggaagtgcagatgaacttcctcaaccagctgaca tcagtctttaaccctagagtctcgtcatcaccatctgtcccgccagagacacaggtggaa gcagagagtgaggatcaagcttccacagatcaaacctcagcggcaaagacgaaaagcata ttcatcgctcagaatgtagccagcctgcaagaacttggtggctctgaaaaactgctgaga gtgtgcctgaacctcccctactttttgcgatacataaatcgatttcaggatgccgtgtca gccaactcattttttatcatgccagccacagtggcagatgccactgctgttcgcaatggg tttcattcgctggtgatagatgtgaccatggcactggatactctgtctctgcctgtactg gagcccctgacacccacgcgtctccaggatgtgactgttctcgctctcagctgtctctat gcaggtgtgagtgtggcaacttgcatggccatcctacacgtgggtagcactcaacaggta cgaaccgggtcaacaagttccaaagaagaagattatgaaaatgatgctgctactattgta cagaaatgtcttgaaatctatgaaatgatcggacaagccatcagcaattcacgccgtgcg gggggtgagcattatcagaacttccagctgctcggggcttggtgtttgctaaacagcctc ttcctcatcttgaacctcagccccacagccttggctgataagggaaaggagaaagatcca ctggctgctcttcgcgtcagagacatcattgctcgtactaaggaggctgctgggtctccc aaactgggacctgggaaagggcatcaagggtttggtgttctgtcagtggtgctagcaaat catgctattaaattgctgtcatcgctctttcaagatctgcaagtggaggcattgcacaag ggctgggagagtgatggtccaccagcagtcctggatatcatggctcaaagcacatccatc cagagaattcagcggctgatagattctgtaccgctcacgaatttgctgctgactttgcta tctacttcctacagaaaggcttgtgtcttgcagcgtcagagaaagggctccgtgagcagt gacgcaagtgcctccactgattcgaatacttactatgaggatgattttagcagcactgag gaggacagcagccaagatgatgacagcgaaccaatccttgggcaatggtttgaagagaca atctctccaagcaaagagaaagtggcccctccgccaccccctccaccgccgcctttggag agctcacctagagtgaaaagccctaacaaacaggctgccggagagaacgggaacatcctg gccagccgcaaagatccagaattgtttttgagcctagcttcaaacattttgaactttatc acttcttctatgctgaactccaggaataacttcattcgcaactacctgagcgtctctctt tcggagcagcacatggctacgctggctagcatcatcaaagaggtggataaggacgggctt aagggcacgtcagatgaggagtttgctgctgcgctgtatcacttcagccattccttggtt acctcagatcttcagtcccctgccttgcagaacacgcttcttcagcagctgggagttgcc cctttttctgaaggtccgtggcctctctacatccatcctcaaagtttgtcagtgctctca cgacttctcctgatttggcagcacaaagccacggcccagggagatcctgacgttccagaa tgccttaaaatttgggaaaggtttgtgggcacactgaagcaaaatgccttgcaggggact cttcccagtgacacggaagatctgaatgttgaacatctccagctgctgctgcttattttt cacaatttctctgagaggggccgcagatctatcatgatgctttgtatccagacaattgtg gaactgacagtgaacatggatacccagcaatgttctgtgccgcttatcgtggcacgtctg ctcttggtgtttgactacctgctccatcagtattccaaggcccccatgtacctgtttgaa caggtgcagtataatttgctgacaccacccatcggctgggtgagtggatcccaggacagt agcagacaaacatctgtcccactttatcatgggtttaaagaagtggaagaaaactggacc aaacactgttcatcagatgcagttccacagcccagattctacagcatcctatctctagaa gcttctgaagatgatatgaaccgtctagatagcacggtttgtgaggtccttttctctagg actgtgaagtatgatgagctttacactgccctgacttcattacttgcagctgggtcgcag tttgatacactcaggaggaaagagaacaaaaatgtcaccgcactggaagcctgtgcactt cagtactacttcttgatactgtggcggatactaggcattttgcctccatccaaaagctac atgaatcaattagctatgaacacacccgagatgagtgaatgtgatattttacacacattg cgctggtcttcccgtctgcgaatcacatcttacgtcacatggatcaaggatcaccttacc aagcagggcatgaaagctgaccatgctgcttctctcattgagctggcctccagcaagtgc agctcagtgaagtacgatgtggaaatagcggaggaatactttgctcgacagatatcttct ttctgtgctgtggattgcacaactattctccaactgcacgaagttcccagtttacagtcc atttacacccttgatgctgcaatttccaagattcaggtttctctagatgagcacttttcc aagctagctgcagaaactgatccacacaagtcttcagagataaccaagaacctcctgcct gctacgctacagcttattgacacttacgctacgtttaccagatcttacttgctacggagc ctctctgaagagggctccactgaaaacaaaccctctgaagagaagctgcggggttatgct gctgtcctggccattggatccagccgttgcaagtctaatactctaggtccaacacttgtt cagaacttgccgtcagctgtgcagactttatgtgaatcatggaacaacattcatacaaac gagtttccaaatattggctcgtggcgcaatgcctttgcgaacgacacgatccccgccgaa agctacatcagtgcagttcaggccgcccacctcggtactctctgcagccaaagtctacct cttgccgcgtccctaaaacacacccttctctctctggtcagactcacgggggatctcatt gtctggtcagatgatttgaacctgccacaggtgattcattccctgttgcccctcctgttg gagaccagcacagagagtgtggcagagataagcagcaactcccttgaaaggatcttgggc cctgcagaatcagatgaattcctggcacgtgtttatgagaaattgatcacaggatgctat agcatactggcccatcactctgatccgaacagtggcctggatgagtccgtcttggaggag tgtttgcagcatctggagaaacagctggagagcagccaggcccgaaaagccatggaggaa ttcttttcagaaagcggagaactggtccagatcatgatggcgacagctaatgaaaacctc tcagccaagttctgtaacagggtgctgaaattcttcaccaagctcttccagctaactgag aagagtcccaaccccagcctgttgcgactttgtggctctttggctcagctggcctgtgtg gagccggtacgtctccaggcctggttaaccaggatgaccatgtccccacccaaagattct gatcagctggatgttgtgcaagagaacaggcagctgctgcaactcttaacaacttacatt gtccgggaaaacagccaagtcggagaaggcgtgtgcactgttctgctgagtactctaata ccaatggcggcagaaatgttggccaatggcgatggcacaggctttcctgaactgatggtt gtgatggcaactttggcgagtgcaggacaaggtgcgggacacctccagcttcatggtgct gctgtagattggctaggcagatgcaagaaatacctgtctcaaaagaatgtggtagaaaaa atgaatgcaaacgtcatgcaagggaagcacgtgactatcctggagtgtacgtgccatatt gtctcttacctggccgatgtcactaatgcgctgagccagaccagcggccaaggaccaagc catctctctgtcgatggagaggaacgggccattgaggtggattcagactgggtggaagag ttggcagtggaggaggaggactctcaggccgaagattcggatgaagattctctttgtaat aaactctgtaccttcaccatcacacagaaagaattcatgaatcagcattggtatcactgt cacacttgcaagatggttgatggggttggtgtttgcacagtttgtgctaaagtttgtcac aaggatcatgagatttcttatgccaaatacggatcattcttctgtgactgtggagccaag gaagatggcagttgcctggctttggtgaagagaactcccagcagtggtatgagctctacc atgaaagaatccgccttccagagtgagcccagagtgcccgagagcgtcattcggcacgca agcacctctcctgctgagaaagccaaggtcaccatcagtgaggggaagggcactgacgaa gaaaaacccaagaagagcagcctgtgtagaaatgttgagggctgtcgagaggaattgcag tcccaggccaacttctcctttgcaccgctggtgctggagatgctgaatttcctgatggat gccattcagatcaacttccagcaagcgtcggccatggggagcagcagtcgcgcacagcag gctctcaatgagctgcatacgttggacaagtcagtagaaatgacagatcagttgatggtc ccaacccttggctctcaagaaggtgcttttgagaatgtccgcatgaactacagtggtgac cagggccagacgatccggcagctgatcagcgctcacgtgctgaggcgagtggcgatgtgt gtgctgtcgtccccgcatggacgtcggcagcacctggctgtgagtcacgaaaagggcaag attacagtccttcagctctcagcattgctgaaacaagcagactccagcaaaagaaaattg acccttactcgccttgcatctgcacccgttccatttacagtactgagcctgactggaaat ccctgcaaggaggactacctagctgtgtgtggactgaaagactgccacgtgttaacattc agcagctctggatcagtctctgatcatttggtccttcatcctcaactagccactggaaat ttcatcattaaagccgtgtggctgccaggatctcaaacagagctggctattgtgactgca gactttgtgaagatttacgatctctctgtagatgccttgagtccaactttctatttcctt ctgccgagttccaaaatcagggatgtcacgttccttttcaacgaggaggggaagaacata atagtgatcatgtcctcggctgggtacatctatacgcagctcatggaggaggcgagtagt gcccagcatggacctttctatgtcaccaatgtgcttgaagtcaatcacgaggacctgaag gacagcaacggccaggtagcgggaggtggtgtgtcagtgtattactcccacgtgctgcag atgttgttcttcagttactgtcaaggcaaatcctttgcagccaccatcagccgggccaat ctggaagtgcagcggctattcccgattaacataaagagttcaaatggtggaagtaagact tccccggcgctgtgtcagtggtctgaggtgatgaaccatcctggcttggtgtgctgtgtt cagcaaaccatgggtgtcccactggtggtcatggtgaagccagacacctttctcatccag gagattaaaaccttgccagccaaagcaaagattcaggacatggtggccatccgtcacaca gcctgcaatgagcagcagaggactactatgatcctcctgtgcgaagacggcagcctgagg atctacatggccaatgttgagaatacctcctactggctacagccctctcttcagccgagc agcgtcatcagcatcatgaagccagttcgcaagcgcaaggcagctgctattacaactcgc acatccagccaagtgaacttccctattgacttctttgaacacaaccagcagctcacagat gtggagtttggaggcaatgacctgctgcaggtttacaatgctcagcagataaagcaccgg ctcaattccactggcatgtatgtggccaacacaaagcctgggggtttcaccattgaagtg acaaacaataacagcacgatggtgatgacaggcatgcggatccagattggcacacaagcg attgagagagcgccctcgtacttggagatctttggccgcaccatgcagctgaacatgacc agggctcgttggtttgatttccctttcactcgtgaggaagccttgcaggctgacaaaaaa ctaaccatcttcattggggcttccgtggatcctgctggagtcacaatgatggattccata aaaatatatggcaaaaccaaagagcagttcgggtggcctgatgagccccccgaagatttc ccatctgcttcagtgagcaatgtttgtcccccaaatctgaatcaagggaatggcactgga gacacggaattggctacccctgctgctgccagtgggactgtcctggagaggctagtagtg agttctttagaagcgctggaaagctgctttgctgtaggaccagtcaacgagaaggagaag agtaaggtggcagctcaggagctggctactatgctgctgtccatgccagctccttccagc gtccagcagcaaaccaagagcctcttggctagcttgcacaccagccgctcagcataccat aaccacaaggatcaagcattgctaagtaaagccattcagtatttgagttcctcaaccaaa gaaggaaaggacctggatcctgaaatatttcagaggctggtcatcactgctcgatccatt gctattatgagacccaacaatctagtccactatacagagtcaaagctgccacagttggaa acagagagcgaagaagggcaagaggcccagaaacacgctgaaggagatggctgcacattt attatccagctggtcaaccacttctggaagctacatgcatcaaaaccgaaaaacgccttc cttgcccctgcctgcctgccaggtctcactcatgttgaagccacagtcaatgctttggtg gatattatccatggatactgcacgtgtgaactggattgtatccatacagcatcgaagatc tacatgcagatgttactttgcccagatcctgcagtgagcttttcttgcaaacaagctttg atcagagtgctgagaccaaggaacaagcggagacacgtcaccttgccatcctcccctcgg agcaatactcctatgggagataaggatgatgatgatgatgacgatgcagaagacaagcta cagagttctgggatagcaaatggcgagcatatccgacaagaaagccaggagcaaagcgaa gttgatcatggggactttgagatggtgtctgaatctatggttctggagacttctgaaaat gtgaataatgggaacccttctcccctggaggctcttctggctggagcagagggattccct cctatgctggatattcctccagatgcagatgatgaaacgatggtggagttggctattgcc ctgagcctgcaacaagatcagcaagggagcagcagtagtgcacttggacttcagagctta ggactgtctggccaggcacccagctcttcttctcttgatgctggaacactctcagataca acagcatcagctccagcgtccgatgatgaaggcagcacagctgcaacagatggctcaact cttcggacttcacctgcagaccatggtgggagcgttggctctgagagcggtggcagcgcg gtggactctgtggccggtgagcacagtgtgtctggtcgtagtagcgcttatggggacaca acagctgagggccaccctgttggaccaggcagcatcagctcgagcacgggtgctatcagc actaccacaggccagcaagagggagatggttcagaaggggaaggtgaggcagagggagac gtccacaccagcaacaggctgcacatggtccgactgatgttgctggagaggctgctacaa aacttacctcagctgaggaacgttggaggagtccgggccattccctatatgcaggttatt ctgatgctcacaacagacctagatggagatgatgagaaagataagggagctttagataac cttctgtcccagctgattgcagaactttgcatggacaaaaaggatgtgtccaagaaaaat gaacgctctgctgtcaatgaagtgcacttggtggtaatgaggctgctgagtgtgttcatg tccagaacgaagtcaggatccaagtcttccatttgtgagtcgtcctccctcatctctagt gccactgctgctgcattgttgagctctggtgctgttgactactgtctgcacgtgctcaag tctttgctagagtactggaaaagccagcagaatgacgaggagcccgtagccaccagccag ctcctgaaacctcacactacatcttctccacccgacatgagcccttttttcctccgccag tacgtgaagggtcatgctgcagatgtttttgaggcctacactcagctcctgacagagatg gtgctgcggctgccctatcagatcaagaagattgcagacacaaactcccgcatcccacct cccatctttgatcactcctggttttactttttgtctgagtacctgatgatccagcagact ccgttcgtgcgccgccaagtccgcaagcttttgctctttatctgtggatcaaaggataaa taccgccagctcagagaccttcacacgttggactctcatgttcgtggaattaaaaagctc ctagaagagcaaggcattttccttcgtgccagtgtggtcacagcaagttcaggctctgcc ctgcagtacgatacattgatcagcttgatggaacatttaaaggcttgtgcagagattgcc acacaacgaacagtgaactggcagaaattctgcattaaagatgactcggttctctatttc ctccttcaagtcagcttcctggtagacgagggagtgtcgccggttctcctgcagctactg tcttgtgctctgtgtggcagcaaagtgctgtctgtggcttcatcctctgggtcgtcgagc acctcttccacctctgctgctgcagcatctggctctgtgcagccagcaacgcagagcaaa tcctccaccaaaaaaagcaagaaagaagaaaaggaaaaggagcgagagggcgagagtttg ggcagtcaggaagatcagctgtgtacagctctggtgaaccagctgaacaagtttgctgat aaggagaccctcattcagttcctgcgttgcttcctgctggagtccaactcgtcctccgtg agatggcaggcccactgcctcgcgctccacatctacaggaactctaacaagtctaagcag gtattactgttggatctcatgtggtcaatctggccagagcttccagcctatggaagaaag gctgcccagtttgtcgatctcctgggatacttctctctgaaaacacagcagactgagaaa aagttgaaggaatactcccaaaaggccgtggagatcctccgtactcaaaaccacattctt accaaccacccgaactccaacatttacaacacgctgtctgggctggtggagttcgatggc tattacctggagagcgatccttgccttgtctgcaacaacccagaggtgcccttctgttac atcaagctttcctccattaaagtggacacgcggtacaccaccacccagcaagtggtgaaa ctaatcggtagccacaccatcagcaaagtgacagtgaagataggagacctgaaacgcacc aaaatggtccgaaccatcaacctctattacaacaacaggacagtgcaagccatagtggag ctgaagaacaagccggctcgctggcacaaagctaaaaaagtccagctgaccccaggccag acggaggtgaagattgatttgcagctgcccattgtggcttcaaacctgatgattgaattt gcggatttctatgagaattaccaggcttccacggagaccctgcagtgcccgcggtgtagc gcgtctgtcccagccaacccgggggtgtgtgggaactgcggcgaaaacgtgtaccagtgc cacaagtgcagatctattaattatgacgagaaagatcccttcctttgcaatgcctgtggg ttctgtaaatacgctcgctttgacttcatgttgtatgccaagccttgttgtgccgtggat cccatagagaatgaagaggatcgaaagaaggcggtaacaaatatcaacactctcctggac aaggctgaccgagtgtatcaccagctcatgggacaccaaccacagctggaaaacctcctg tgtaaagtgaatgaggcggctcctgaaaagccacaggatgaatctggtagtagtggaggg ataagttctacctcagctagtgtgaatagatacatactccagttagcccaggagtattgc ggtgactgcaagaactctttcgatgaactttccaaaatcatccagaaagtgtttgcctct cgaaaggaactcctggaatatgatctccaacagagagaggcagcaacgaagtcctcgcga accactgcccaacccacgtttactgccagccagtatcgtgccttgtctgttttaggctgt ggccacacatcatcaacgaaatgctatggctgtgcctcagccgtcactgaacactgcata acgctgctccgggctttggccaccaactctgccatcaggcatatccttgtgtcccagggc ctcatccgagagctctttgactacaacttgcgccggggcgcagccactatgcgggaggag gtccatcagctcatgtgccttctgaccagggacaatccagaggccacacaacaaatgaat gacttaatcatcgggaaggtttctgcagctctgaagggacactgggcaaatccagacttg gctagcagcctccagtgtgaaatgttgctgctaacagattccatttcgaaggaagacagc tgctgggagctccgactgcgttgtgctctcagcctctttctgatggcagtgaacattaag actccagtggttgttgagaacatcaccctcatgtgcctgcgcattcttgaaaagctgatc aagccacctgctccaaccagcaagaaaaacaaggatgtgcctgtggatgctctcaccact gtgaagccttacagcaatgaaatccatgcacaagctcagctgtggctcaagagggacccc aaagcatcctatgaagcttggaaaaagtgcctccctgccagaggtgtagatgccaagggg aagtctctcagcaaagctgagcttcaccagctctacttgtcggaaaaatatgtctggaaa tggaaacagttcatgagtcgtcgtgggaagagaacttgccctctggatctcaagctggga cacaacaattggctgcgacaggtgctgtttactcctgccactcaagctgcaaggcaagct gcgtgtactattgtggaagctctggctaccatccccagccgcaaacagcagatccttgat ctcctgacaagctacctggatgagctgagcattgctggtgagtgtgccgccgagtacctg gcactgtaccagaaactcatcaaaccggcccactggaaggtctacctggcagccaggggt gttctgccctatgttggcaacctcatcactaaggaaatagctcgtttacttgccttggag gaagcaacactcaacacggatttgcagcagggatatgccttgaaaagtctcacaggtctt ctctcttccttcgtggaggtggagtccatcaaacggcacttcaaaagccgcctggtgggt acggtcctgaatgggtacctgtgtttgaggaagcttgtggtacagagaacaaagctgatc gatgaaacccaggacatgctgctggagatgttggaagatatgacaacaggcacggaatct gaaaccaaagcatttatggcagtgtgtatagagacagcgaaacgttacagtctggatgac tacaggactccggtcttcatctttgagagactatgcagtattatctatcctgaagagaat gaagtgacagagttctttgtaactctggagaaagatccccagcaggaagacttcttacag ggcagaatgccaggaaatccctacagcagtaacgagcctggcattgggccactgatgagg gacgtcaagaacaaaatctgtcaggactgtgacctggtggctctgctggaggacgacagt ggaatggagcttttggtgaacaataagatcatcagtttggatctgcctgtggctgaggtc tacaagaaggtgtggtgtcccactaatgagggggagccgatgaggatcatttaccgcatg cgagggttactaggagatgcaactgaggaattcatcgagtctctcgactctactactgat gaagaggaggatgaggaagaagtttataagatggcaggtgtcatggcccagtgtggaggc ttggagtgcatgcttaacagactgactggaatcaaggacttcaaacaaggccggcacctc ttgaccgtgctgttaaaactgtttagttactgtgtgaaggtgaaaataaatcgtcagcag ttggtcaagccggagatgaacactttgaatgtcatgcttggaactcttaacttggctctg gtggctgagcaggaaagtaaggacagcggaggagcagccgtggcagaacaagtgctcagt ataatggagatcatactggatgaatccaacgcagagcctctgagcgaggacaagggtaac ctcctcctaaccggtgacaaagatcagctggtaatgttgctcgatcagattaacagcact tttgtccgttccaatctcagcgtcttgcaaggcctattacgcatcatcccttacctgtcc tttggggaaatggagaaaatgcagatcctggttgatcgattcaagccctactgtaacttt gataagtatgatgaggagcacagcggagatgataaagttttcctggactgcttctgtaaa atagcagcgggtataaagaacaacagcaacggccatcagctgaaagatctcatccttcag aagggaattacgcagaatgcccttgactacatgaaaaagcacattcccagtgcaaaaaat ttggacgcagacatatggaagaaattcttatctcgacctgcacttccttttatcctgcgc ctgctccgtggacttgccacacagcaccctgcgacgcaggtgctaataggtacagactcg attaccaacctgcacaaactggagcaggtgtctagtgacgaagggatcgggacgttagca gagaatcttctggaggcactgagggaacatccggaggtgaataagaagattgatgctgcc cggaaggagacgcgtgcagagaagaagcgtatggccatggcaatgagacagaaggccttg ggcactctggggatgacgacgaatgagaagggtcaggtagtgaccaagacggcgctgctt aaacagatggaggagcttatagaagaaccaggtctgacttgctgcatctgccgggaagga tacaagtttcagcctacgaaagtcctaggtatttatactttcaccaaacgcgttgcacta gaggagtttgagaacaagccccgaaaacaacagggatacagcacagtctctcacttcaac attgtccactatgattgtcacctcgcagcggtaagacttgctcgcggccgtgaagaatgg gagagcgcagccctacaaaatgccaacaccaagtgtaatgggctcctgccagtctgggga cctcatgtgccagagtctgcttttgctacttgcttagcacgacacaacacgtacctccag gaatgcacagggcagcgggagcccacctaccagctcaatgtccatgatattaagctgcta tttctccgttttgcgatggagcaatcattcagcgtagatactggaggaggaggaagggag agcaacatacacctcattccatacataatccacacggtgctctacgtcctcaacacaaca cgagcaacttcgagggaggagaaaaacctccagagcttcatggagcaccccaaagagaag tgggtggagagtgcctacgaggtggacgggccccactattacaccgtgctggcgctgcac atctcgccccccgagaagtggaaagccatgcgagtggagatcctcaggaggctcctggtg acctcccacgcgcgggtggtctcgccggggggagccagcagactggcagataaggcagtg aaggaatacgcaatgtaccgctctggccttctcttctgggccctagtagatctcatttac aacatgttcaagaaggtgcctaccagtaacacagagggaggctggtcctactctcttgct gaattcatacgacacaacgacatgccaatacacgaagctgcagacaaggccctgaaaacc ttccaggaggagttcatgccagttgaaacgttttccgagtttttggatgtggccggactc ttatcagaaatcggtgatcccgacagcttcctcaaggatcttttgaactccatcccctga

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