Oncorhynchus keta (chum salmon): 118395226 Help Entry 118395226         CDS       T09424                                  Symbol obscnb Name (RefSeq) obscurin isoform X1   KO K17531   obscurin-RhoGEF [EC:2.7.11.1] Organism oke  Oncorhynchus keta (chum salmon) Pathway oke04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:oke00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     118395226 (obscnb)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:oke01001]     118395226 (obscnb)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:oke04131]     118395226 (obscnb) Enzymes [BR:oke01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      118395226 (obscnb) Protein kinases [BR:oke01001]  Serine/threonine kinases: CAMK group   Trio family [OT]    118395226 (obscnb) Membrane trafficking [BR:oke04131]  Others   Rho GTPase associated proteins    Rho guanine nucleotide exchange factors (GEFs)     118395226 (obscnb) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  I-set Ig_3 ig Ig_2 V-set Ig_5 Ig_4 Izumo-Ig Ig_6 V-set_CD47 C1-set fn3 SOS1_NGEF_PH RhoGEF Ig_DSCAM-DSCAML_C C2-set_2 Ig_CD22 PH SH3_2 PapD_C Motif Other DBs NCBI-GeneID:  118395226 NCBI-ProteinID:  XP_052319836 LinkDB All DBs Position 15:33489501..33595352 Genome browser AA seq 6802 aa AA seqDB search MDQNLFGGAPRFLTRPKAFAVCVGKDATLSCTIVGNPTLLITWEKEKLRLTSGGRFKTVD DGNVYRLTIYDLTLEDSGQYMCRAKNNVGEAYACVTLHVGLPQEMVDRAPVFMVKPTSAR VGLGGDVVFHCRVAAYPEPKFDWDKDGRYLAETNRIKVSSDGDSSSLRIQSVRSLDSGTY TCRAQNSVGRSNSAAALVIDTQDSRHLGQDKSTSLLSHMQKRKEGISIYRTGETRSSSHN STTTSSTATTMVTDGLSALGLDHGSAALVSQLPKSVFTRTCTVTEGKHAKLSCFVTGHPK PHIIWRKDGGNIGEGRRHIMYEDQAENFILKILYCKQSDNGLYTCNASNMAGQTYSAVLV IVKEPKVPFRRKLQDVEVQEKMTAMLLCEVPVSASQASWFMEETRLEDSSKYCMEEEGTM RRLTIRNVTTNDDAVYICEMKEGSRTVAELTVLGNITKKLPRRTVVSVSDTVIFCVELEH PCSDAYWTRNGERLKPDTRISIASTLRQYTLTISHCQADDSGEVAFVAGDCKTSTRFSVA AARKHPPDPPIDVVVRSKTDSSITLHWSPPDSDRPVPIKGYMVERRKVGAQTWQRCNGME VSPFTEITIQNITEEASYQFRISAVNDYGQSQYMEVPGTFYLEPSAEVKTGLMNSTAISG EEASLSVDLSAVCSGSWSINGRLLRSGADYLITRQTTTHTLTIRTVSMEMKGATVKFVGG GSESTCILQVKAPAVRFTSKSAHTEVVTCSAQSSAQLTTEVSDYDAQVVWMKNGRELKVG KKYECMSTDRKRMLMVHNVTEEDTGIYECVLNEDRMSLQLSLKDEAKFLNKPRGPMEVAP ALSGDLELNCEVSSASGVVVWRKDQTLVTEDQRTTVVSKGTQRRLVIKNAKKSDEGHYSC ETVDDKVTFQVKIKEAQQAVFTNKESVQKEVKVTLSQKATLSCEVSDPKTEVKWYKSGKL LTSTETVSTETKGRSRLLVVDKIEKKDAGEYTCEARAEKLVFKIHVSETQQSAFTNKESV QKVKATLSQKATLSCEVSDTKTEVKWYKDGKLLTSSKTVQMETKGKTRQLVIEKVEKKDA GEYTCEVGVEKLVYKIQVTEAQAVFTNKESVQKEVKVTLSQKATLSCEVSDTKTEVKWYK DGKLLTSSKTVQMETKGKTRQLVIEKVEKKDAGEYTCEVGAEKLVYKIQVADAQQAAFTN KESVQKEVKATLSQKATLTCEVSDTKAEVKWYKDGKLLTSSKTVSMETKDKTRQLVIEKV EKKDAGEYTCEVGTEKLAYKIHVTGETQAAFTNKESVQKEVKVTLSQKATLSCEVSDTKT EVKWYKDGKLLTSSKTVQMETKGKTRQLVIEKVEKKDAGEYTCEVGADKLAFKIQMAETQ AAFTNKESVQKEVKATLSQKATLRCEVSDTETEVKWYKDGKLLTSSKTVSMETKGKTRQL VIEKVEKKDAGEYTCEVGADKLAFKIQMAETQAAFSNKESVQKEVKVTLSQKATLSCEVS DQKTEVKWYKDGKRLTTSKTVHMETKDKTRQLVLDIVEKKDAGEYTCEVGAEKVAFKIQV AEVQAAFTNKESVQKEVKVTLSQKATLSCEVSDTKTEVKWYKDGKLLTSSKTVSMETKGK TRQLVIEKVEKKDAGEYTCEVGAEKLAFKIEVAESSAKFKKTAVKSACSVQASEKIVLTT ELTSESASVKWFRDGVELKESSKYDMKREGHSRTLIVKSTEVKDSGTYSCHTADDKLEFK VQVKDSPLKFVVQLQPVATELGGTLTLTCEMNRALGDVLWRHDSCEVKPGGKFCVSTDGP KRVLTVTGMAKEDEGEYSCECKDDKTSAKVSTKAPRLVKLTSKLSNVAAVEGKEAIFKCS VTPADVNVKWFCNNVPITAGPKYKIEHGGTSHSLTVTSVSQDDAQEISIDAEGKTCSATL QVQLEPVMFKKKLENVMAVEEQKEVKLEVELSKPSKEVRWMKNSVVLQPGGNMEIRLDGA KQTLVFKSVTTADRGYYSCETLDDKTQAKLTVDVKKIEVVNGLLPEVKAHEKETVTLEVE LSQADVEGSWTRDSVKLKAGSNCRITALGKKHALTLSQINMEDAGTIAFQAEGVKTSAKL IVTEPAAMISKPMEDVKAPEKEKATLECEVSRTNAEVKWFKGDMELKPGKNFRIHSQGRT RSLLIHKCSQEDEGTYVCQTSDDNTSAKLTIHARDIRIVKRLEDVEVMEKESASFFCEIS HDEVDCQWFKGDTKLKVGDNIKMRQEGQIYVLLFKSVTPEDIAEIKFTAEKASSTAKLTV KELPVQFVKKLRDKLALYTHRGFLECQVSRASAKVKWYKNKKEIKPSKKHEISSEGIYRK LTINDVGSDDEDTYTCDAIDDKTSCKLLVEEQAISVVRELSAVEVTEPFAAFFEVEINID SVKPPKWTLNGVAVQESADVEMEKEGSMHRLTFKKTKASMTGPVQFMAGKSKSVAQLTVK ERPLEVVEPMKDVKVKEKGSATLSCKFSATPKEVSWFKGQTLLDASDKYSLKQDAVRAQL TIQKLTGEDTGEYRCQSAAAETKATLTVEVRKVEITKHLVDTEVDEDSDAVFICEINYTD EEVQWLLNEKALFSNEVNTITHVGKVHTLTLKNLAPEDGGTIIFKVREIKEGVTLKVEEK RAVFLKSLDDVVGEVKGMITLACEASKPRVSPAWRKDGTLLTTDSKYEVLHTGKSLGLII KDVTKEDAGEYSCDLGTELSKSKVTVRDLSIGITKQLKSVEAMEGETCSFQCILSRESTD ECSWTLNGQTVANGGRIQVSSTGRKYMMVIKDVTPADAGEVVFNIKNLNSKTTLAVEGKA QSVSQELQSISVVSGEDAVFICEVTQTRATVQWAKDGKDIRKSEKYEISKEERVMKLTVH SVTVQDSGEYSCEVIGGATTKAKLEIKEPVHKFTKELKDSEVEEEGSVTLQCETAQPASK ATWSKEGVELKAGGRYEMSQKETVLTLTIKQLEEKDSGTYTCDVGTATMMAKVTVKALPA SFEQKLKNQQAKEGESVTLCSVLSKPGAKVQWKKGTEHLKAGDKYEMKQKDASCELQIKH LNVEDSGEYSCECGDQRTTATINVNALPVTFKHKLESQEAEEGGSVTLHCELSKPGVPVE WRKGTQVLKSGEKYQLKQKESVSELLISKALPEDSGDYSCVCGDQKTTASLKIKAQPVTF KQKLGSQEAEEGGNVTLHCELSKPGVPVEWRKGTQVLKSGEKYQLKQKESVSELLISKVV PEDSGDYSCVCGDQKTTASLKIKAQLVTFKHKLESQEAEEGGNVTLHCELSKPGVPVEWM KGTQVLKSGEKYQMKQKESVSELLISKVVPEDSGDYSCVCGDQKTTASLEIKAQPVTFKQ KLGSQEAEEGGSVTLHCELSKPGVPVEWRKGTQVLKSGEKYQLKQKESVSELLISKVVPE DSGDYSCVCGDQKTTASLKIKAQLVTFKHKLESQEAEEGGSVTLHCELSKPGVPVEWWKG TQVLKSGEKYQMKQKESVSELLISKVLPEDSGDYSCVCGDQKTTASLEIKAQPVTFKQKL GSQEAEEGGSVTLHCELSKPGVPMEWMKGTQVLKSGEKYQLKQKESVSELLISKVVPEDS GDYSCVCGDQKTTASLKIKAQLVTFKHKLESQEAEEGGNVTLHCELSKPGVPVEWRKGTQ VLKSGEKYQMKQKESVSELLISKVLPEDSGDYSCVCGDQKTTASLKIKALPVIFKQDLQS QEAEEGGSVTLHCELSKPGVPVEWRKGTQVLKSGEKYQMKQKDCRVDLQVCDLKPGDTGS YQCRTGDTESSACLKVNALPVIFTKELQSQQAEEGGSVTLHCELSKPGVPVEWRKGEVGL CLCAKYNIIQEGHSARLVIQNLDPEDSGSYTCDSGDRKTTAHLSVKALPVYFQTRLQNLE WDAGEIAILRCEITKPGASVVWSRGDRVLESNNKYQLKQEGAIVKLIIYSLQGADSGEYI CDTGYQKTSSVLTVQEVEVTIVKVLNSCSVHEGEDVHFECHLSHDDAKEVQWKLADVPLQ NNEMNLIRAQGKVHSLTLRGVTQADSGTVTFTVGHHTSTASLTVRGAPVVFKKELESQEA VEGGSVSLTCEISADGKVTWRRGSVLLTQGEKYSMEHTGSTYILMVHKLKVEDAGEYTCD AGDKQSTATLTVKESVRITRELHDITVTTGQDAVFACELSQEGVTNGEWWLGDNLLQNND LNQMACQGRVHRLTLQMVTPDESGDVAFVVGEEKTVACLLVEEKPKALILEKPHDTVALE GETVTLSCTVSDPTATVTWSRNDVAINAGLKYDLRKNGALLQLRIHNLEMEDSGTYCCDT GDAQCTVTLIVEGAPAFFQKELKNQEAQEGDDITLHCELSKAGTHVEWRKGGAVLQAGKK YEMRQEGCVQELHIRNLEPEDNGYYTCDAGDQLTTALVAVQEPTVEVVSEMQDLRVAEDQ PAEFICQYSRPVQAQWKRNGRPLQPDGRRVVVEQNWTMARLYISHVSTEDRGTYSCEAEG TCVVASLEVEAKPIEILQGLENMDTIDGGEALFECSISRCEIKDSCWLIDGKPVKDSPTT EIVSFESGRRHLLLLKDLHVGDNCKVTFQAGTAATSAMLNVKGWQLDVVSGLEDKVAVVG EKVEFSCVLTEPVPEAEVAWYSNGAELKKDNTWAMQADGCFYQLVLRQAPAMPPQEITFA ARDAISMAKLTVITFPDPPEDPELVSKHKQGVTLSWFTPLSDGGSPILGYRVEMRLVDSA LWLPCHAEPVCNTEFSVDNLIPGSGYRFRVAAINRAGTGEPVQLPQTVQLEAPITVTQQL ACPSLQEGKMARVECQLSAEGSSVTWLRDNKELEFGLKYQVTIEGKTQVLLIKDFESADQ GVYTCVASDEAESSINLNLPTGGDGVKLEGAQPSLPPEAASEGDVHALWEALAKKRRMSR EPTLDSISELPDEEDKEPKTPKEPVKEKKSPEKVNEKEKEKVVDPVIIAKKELDTNLHTS SEDESRVPTLVSYLKKSSKSSLSASNQTESISTEKFYVQTSVQQTSVQQTTVLQTSSSGQ QITAQTTEITGCGNEEDEEKGLLDAAVKIQAAFKGYKSCKDTCPVFKDVFKDQTKEPNGT IHLECVVERKPDKVRWLKDGEPLVDSKHHHIDIYNDGTCSLVITAVTTKDTGIYTCEVTN KFGVTIHSGKVTVGSAREASGRRPLTMGYSADSEAESSSAESEMDESLRQASKRLRRLLR TRLPATSEEESFVSCDEEAELKAPEPKSYREDERYLYIRFDTRSEAQVASLHFQEMFTAQ GMPVETTIQEAGPLKVELRIMKMGYTQDGSATPTQEKQLPAFMTGAPAAPVFLTELQSQD VSEGYPVSFDCVVIGKPTPSMRWFKDGKLLEENDHYMINEEHEGCHQLIITTVLPSDMGV YRCMAENTSGIAATKAELRVDMSCSSDYDTAADATETGSYISAKGYMSRETEAFESMAED EQIPQVLDELHDVHVSPGSPIAKMQLKVKGLACFPAPRVYWFKDGIPLRSSDRILLLDKR DVHSLEVLEVKREDAGEYSAYISNAAGSAYSSARILVLGPGELTPVEEHDPKVPPVPPRF LEKFSNRKVKQGASVTLSVRVEGSPIPMVTWLKEDSAEDVLWIKPDTKGYKVARSGRQHS LILMDAGSEHAGTYTCIATNRAGQSICTAHFEVEDAPRPKEETKIPLGITISPPVEDAGR RMPYLGEVGTEEFLMKLTSQITEMVSAKISQDSAQNHQVLQWIEAWPKASTSLRVPGGDS DDETKTPSASPHHGRSRPSSILADSSSESDDPDARGEMFDIYVATADYNPTIPNKETISL KEGQYVEVLDSAHPLKWLVRTKPTKTTPSRQGWVSPAYLDKKLKLSADAGDVPETGGEEV SEGEYKRRLLQLIQDMINSEAEFVKEMDFFTSHHVKQVESPDAPSDVTSQKEAIFRNIHE IKAFHSEFMFPKLRECDTDDDVAMRFLRSGEGFEKYLQYLVGQQKAEAAISDKTVHHFFK KYTDKQQASADPAEGPVLSINAYLQKPLDRIQKYKASLKELIRNKARNGQNCCLLEEAYA MVSSLPQRSENTHHVSMIENYPATLDVLGEPIRQGPFMMWEGAPGVRSSSRGHRRHAFLF KNYVVICKSKRDSNTDTQGYVFKNMMKLNNIDVNETVEGDDRAFEIWHEREDSVRKYTLQ ARTVIIKNSWLRDLRDLQQRYTMPGWSMPDFDELLADCTVELGQTVKLACKVTGVPKPVV TWYKDGHAVEADPHHIIIEDPDGSCTLILDNMTADDSGQYMCFATSTAGNASTLGKITVQ VPPRFVNKMRNAVFTVGEDAQFSCTIQSAPSPKIRWFKEGRLLTDQEKYQTYSESRSGVL VLVIKGPTERDLGHYECELSNRLGSARCAADLCLPSAVTRRGEQAITIEVTEQETKIPKK TIIIEETITTVVKNTRMKRRGLSPSGFNRSQTSTPDHQTTPTARQRRQASTNRKTTIPTL YVTEPEGAAGARAAENKWVEVEEIIEYKVNKSPRPSRRGISPAGSERAHTPSSTRPQRSA NPNANNSNNNLVELQNHSELQGAQPLYWDDEEEDGDVAVDGSEVAPGIRGEAYEVSSLLI PNDHEHEEDEAWLEEQQEAFITEPDDDDNTPRKLEPKILTEGSRVLTLEDLEDYVPREGE TFGSSNTRSSPPERPCEISVLQREIGGSAVGQPVLLNVGRPVGMPRERPRPGFFSRFRDH LSGSMFSPAGPHHNYNHHPSGGQSRREIPIQVSHAKLEVKPLYCSEVQRVEGVQQSYKTK VYTSVGKSVTLQISKNNPYQNQ NT seq 20409 nt NT seq  +upstreamnt  +downstreamnt atggaccagaacctgtttggaggggcccccagattcctcacgcggcccaaagcattcgca gtgtgcgtgggcaaggatgccactctaagctgcaccatcgtgggcaaccccaccctactg attacctgggaaaaggagaagctacgtctgacctccgggggccgcttcaagacggtggat gatggtaatgtctaccgcctcaccatctacgatctaactctggaagacagcggccagtac atgtgccgggccaagaacaacgtcggggaggcatacgcatgtgtaacccttcatgtaggc cttccacaggagatggtagacagggcccccgtcttcatggtcaagcctacctctgcacgt gtgggcctggggggcgatgtggtcttccactgccgggttgctgcttacccagagcccaaa tttgactgggataaggacgggcgttacctagccgagacaaaccgcatcaaggtgtcctcg gacggcgacagcagctccctgaggatccaaagcgtgcgcagcctagacagcggcacgtat acctgccgcgcccagaactcggtgggccgctcgaactctgccgccgccttggtcatagac acccaggactcccgtcacctgggccaggacaagagcacctccctcctctcccacatgcag aagcgtaaagaagggatctccatctaccgcacgggagagacccgcagctcctctcacaac tccaccaccacctcgtccacagccaccactatggtcacagacgggctgagcgctctgggt ctggaccacggcagcgcagcactggtcagccagctacctaaaagcgtcttcacccgcacc tgcacggtgactgagggcaagcatgccaagctcagctgcttcgtgacgggtcaccccaag cctcatatcatctggaggaaggatggggggaacatcggcgagggacgaaggcacatcatg tatgaggaccaggccgagaatttcatcctcaagatcctgtactgcaagcagagcgacaac ggcctgtacacctgtaatgcctccaacatggctggacaaacctacagcgctgtgctggtg attgttaaagagcccaaggtgccgttcaggaggaagctgcaggatgtggaggtccaggag aagatgacggccatgctgctgtgtgaggtgcccgtttcggctagccaggccagctggttc atggaggagacacgtctggaggacagctccaagtactgcatggaggaggaggggaccatg cgtcgcctcaccatccgtaatgtcaccactaatgatgatgccgtttacatctgcgagatg aaggaggggagccgcactgtagccgagctcactgtgctggggaacatcactaagaagctt cccaggaggactgtagtgtcggtgagtgatacagtgatcttctgcgttgagctggagcac ccctgttctgacgcctactggacgcgcaatggcgagcgcctgaagccggacacacggata tccattgcgagcaccctcagacagtacacgctaaccatcagccactgccaggccgacgac tcaggagaggtggcttttgtggctggagactgcaagacctccacacgattctcagtcgcg gctgccagaaagcaccctccagatccccctatcgacgtggtggtgcgtagcaagaccgac tcgtccatcaccctccactggtcccccccagacagtgaccgccccgtgcccatcaaaggg tacatggtagagaggaggaaggtgggtgcccagacctggcagaggtgcaatggcatggag gtcagcccctttactgagatcacgatccagaatatcacagaggaggccagctaccagttc cgcatctctgcagtcaacgactacggccagagccagtatatggaggtgcctgggaccttc tacctcgagccctctgcagaggtgaagacaggcctgatgaacagcacagccatctcaggc gaggaggcctccctctccgtggacctgtctgcagtgtgctctggctcctggtctatcaac ggccgcctcctgcggagtggggctgactacctcatcacacgccaaacgaccacacatacg ctgacgatccgaaccgtctcgatggagatgaaaggagccacggtcaaatttgtgggcggt ggctccgagagcacttgtatactccaagtgaaggctccagctgtccggttcaccagtaag tccgctcacaccgaggtggtgacctgcagcgcccagtcctccgcccagctgaccacagag gtgtccgattatgatgctcaggtggtctggatgaagaatggacgggagctgaaggtgggc aagaagtatgagtgcatgagcaccgaccgcaagaggatgctgatggtgcacaacgtcacc gaagaggacacgggcatctatgagtgtgtcttaaacgaagaccgaatgtccctgcagctt tctctaaaagatgaagccaagttcctgaacaagcccaggggtcccatggaggtggcgcct gccctcagcggggacctggagttgaactgcgaggtgtcgtctgcaagcggggtggtggtg tggaggaaggatcagacactggtcactgaggaccaaagaaccaccgtcgtctccaaaggg acacagaggagactggtcatcaagaatgccaagaagagtgacgagggacactactcctgc gagacagtcgacgacaaagtcacattccaggtcaagatcaaagaagcccaacaggcagtc ttcaccaacaaggagtctgtacagaaggaggtgaaagttactctctcccagaaagccact ctgagctgtgaggtgtccgaccccaagacggaggtgaaatggtacaagagcggcaagctg ctgacttctactgagacagtctccacggagacaaagggcaggagtcgtctgttggtagta gacaaaattgagaagaaggatgctggagaatacacctgtgaggctagagcagagaagctg gtctttaaaatacatgtttcagaaacccaacagtctgccttcaccaacaaggagtctgta cagaaggtgaaagctactctttcccagaaagccactctgagctgtgaggtgtctgatacc aagacagaggtgaaatggtacaaggatggcaagctgctgacttccagtaagacagtccag atggaaactaagggcaagactcgtcagctggtaatagagaaggtggagaagaaggatgct ggagagtatacctgtgaggttggagtggagaaactggtctataagattcaggtgacagaa gcccaggctgtcttcaccaacaaggagtctgtacagaaggaggtgaaagttactctctcc cagaaagccactctgagctgtgaggtgtctgataccaagacagaggtgaaatggtacaag gatggcaagctgctgacttccagtaagacagtccagatggaaactaagggcaagactcgt cagctggtaatagagaaggtggagaagaaggatgctggagagtacacctgtgaggttgga gcggagaaactggtctataagattcaggtggcagacgcacaacaggctgccttcaccaac aaggagtctgtacagaaagaggtgaaagctactctctcccagaaagccactctgacctgt gaggtgtctgataccaaggcagaggttaaatggtacaaggatggcaagctgctgacttcc agtaagacagtctccatggagacaaaggacaagactcgtcagctggtgatagagaaggtg gagaagaaggatgctggagagtacacctgtgaagtgggaacagaaaagctggcctacaag atacacgtgactggagaaacgcaggctgccttcaccaacaaggagtctgtacagaaggag gtgaaagttactctctcccagaaagccactctgagctgtgaggtgtctgataccaagaca gaggtgaaatggtacaaggatggcaagcttctgacttccagtaagacagtccagatggaa actaagggcaagactcgtcagctggtgatagagaaggtggagaagaaggatgctggagag tacacctgtgaagttggagcagacaaactggccttcaaaattcagatggcagaaactcaa gcggctttcaccaacaaggagtctgtacagaaggaggtgaaagctactctctcccagaaa gccactctgagatgtgaggtgtctgataccgagacagaggtgaaatggtacaaggatggc aagctgctgacttccagtaagaccgtctccatggagacaaagggcaagactcgtcagctg gtgatagagaaggtggagaagaaggatgctggagagtacacctgtgaagttggagcagac aaactggccttcaaaattcagatggcagaaactcaagcggctttctccaacaaggagtct gtacagaaggaggtaaaagttactctctcccagaaagccactctgagctgtgaggtgtcc gaccaaaagacggaggtgaaatggtacaaggacggcaaacgtctgacaaccagcaagaca gtccacatggagacaaaggacaagactcgtcagctagtgttggacattgtggagaagaag gatgctggcgagtacacttgtgaggttggagcagagaaagtggcctttaagatacaggtg gcagaggtccaggcagccttcaccaacaaggagtctgtacagaaggaggtgaaagttact ctctcccagaaagccactctgagctgtgaggtgtctgataccaagacagaggtgaaatgg tacaaggatggcaagctgctgacttccagtaagaccgtctccatggagacaaagggcaag actcgtcagctggtgatagagaaggtggagaagaaggatgctggagagtacacctgtgag gttggagcagagaaactggccttcaagatagaggtggcagaatcctctgccaagtttaaa aaaactgcagtgaagagtgcatgcagtgttcaagcaagtgagaagattgttttgaccact gagttgacttcggagagtgccagtgttaagtggttcagggacggcgtggagttgaaggag agctctaagtatgacatgaagagagagggacattctcgtaccctgattgtgaagtccact gaagtcaaagacagtggcacctactcttgccacactgctgacgacaagcttgagttcaaa gttcaagtcaaagactcaccgctgaagtttgtggtgcagttgcagcctgtagccacagag ctgggtggtacactgacactgacctgtgaaatgaaccgagccttaggggacgtgctctgg cgccacgacagctgtgaggtcaaacccggcggcaagttctgtgtcagcactgatggtccc aagcgggtccttactgtgacaggaatggcaaaagaggatgagggagaatacagctgtgaa tgcaaagatgataagacctctgccaaggtctccaccaaagcacccagactggtgaagctg acttccaagctgagcaacgtcgctgctgtggaggggaaggaggccatcttcaagtgtagt gtcaccccagctgacgtcaacgtgaaatggttctgcaacaacgtgcccatcactgctggg cccaaatataagattgagcatgggggcaccagccactccctcaccgtcacctcagtcagt caggatgatgctcaagagatcagtattgatgcagagggaaaaacctgcagtgctaccctc caagtgcaactggagccggtgatgttcaagaagaagctggagaatgtgatggcggtggag gaacagaaggaggtgaagctggaggtagagctgagtaagccctctaaagaggtcaggtgg atgaagaacagcgtggtgctacagcctggaggcaacatggagatcaggctggatggagcc aagcagaccctggtctttaagagtgtgactacggccgaccgtggttactactcctgtgag accctggacgacaagacccaggccaaactcacagtggatgtgaagaagattgaggtggtg aacggcctgctgccggaggtcaaggcccatgagaaggagacagtgacccttgaggtggag ctcagccaggctgacgtggagggctcctggaccagggacagcgtcaagctcaaggcaggg tccaactgccgcatcacagccctgggaaagaagcacgccctcacactatcccaaattaat atggaggacgcagggacaattgccttccaagcagagggagtcaaaacttctgccaaactc attgttacagaacctgcggctatgatctctaaacccatggaggatgtcaaagccccagag aaggagaaggctacgcttgagtgtgaggtgtccagaactaacgctgaggtcaagtggttc aagggtgacatggaactgaaaccaggaaagaactttcgcatccactcccaggggcgcaca cgcagcctgctaatccacaaatgttcccaagaggatgagggcacatacgtctgccaaacg tctgatgacaacacatcagctaaactcactattcacgcccgagacattcgaatagtgaag aggcttgaggacgtggaggtgatggagaaggagagcgcttcgttcttctgtgagatctct cacgatgaagtggactgccagtggttcaaaggcgacaccaaactcaaagtcggtgacaac atcaagatgagacaagagggtcaaatctatgtgctgctgtttaagtcggtgaccccagaa gacattgctgagattaaattcacagctgaaaaggcctcttcaacagccaaactgacagtg aaagagctccctgtccagtttgtgaagaagctcagggataagttagccttgtatacacac cgtgggttcttggaatgccaagtgtcccgggccagcgccaaggtcaagtggtacaagaac aagaaggagatcaagcccagcaagaagcacgagatcagcagcgagggtatataccgcaaa ctcaccataaacgacgtgggctcggatgatgaggatacttacacctgtgacgccatcgac gacaagacatcctgtaaacttcttgtggaagagcaggccatcagcgtcgtacgggagcta agtgccgtggaagtgaccgagccctttgccgccttcttcgaggtggagatcaacatcgac tcagtcaagccccccaagtggaccctgaatggtgtggccgtgcaggagagcgctgacgtc gagatggagaaggagggctccatgcaccgcctcacctttaagaagaccaaggcctccatg acaggacctgtccagttcatggctggcaagagcaagtctgtggcccagcttactgtcaaa gagcgtcctcttgaggtggtagagcccatgaaagatgtgaaagtcaaggagaagggctca gccactctgagctgcaagttctccgccacacccaaagaggtgagctggttcaaagggcaa accctcctggatgcttcagacaagtacagcctgaaacaggacgctgtgagggctcagctg accatccagaagctgactggggaagacaccggggagtaccgctgtcagtcggctgctgcc gagaccaaagccactctcactgtagaggttcggaaagtggagatcaccaaacacctggtg gacacagaggtggatgaggacagtgatgcagtgttcatttgtgagatcaactacactgat gaggaggtgcaatggctactcaatgaaaaagcactcttctccaacgaggtcaacaccatc acacacgtgggcaaagtgcacacgctcacactcaagaatctggcccctgaggatgggggc accatcatcttcaaggtcagggaaatcaaggagggtgtgaccctaaaagtcgaagagaag cgtgcagtgttcctcaagtctctggatgacgtggtgggagaggtgaaaggtatgatcacc ctggcgtgtgaggcctccaagcccagggtctcccccgcctggaggaaagatggtacgctc ctgaccactgactctaagtatgaggtcctgcacacaggcaagtccctgggtctgatcatc aaggatgttaccaaggaagacgcaggggagtacagctgcgacctgggtactgagctttcc aagtcaaaggtcactgtgagagacctgagcataggtatcaccaagcagttgaagtccgtg gaggcgatggagggagagacatgtagctttcagtgtattctgtcacgggaaagcactgac gagtgttcctggaccttgaatggccagaccgtggctaatggaggacgcatccaggtctcc agtacaggtcgcaagtacatgatggttatcaaggatgtgacgccagccgatgctggtgag gtggtcttcaacatcaagaacctgaactccaagactaccttagctgttgaaggcaaagct caatctgtatcacaggagctgcagagcattagtgtagtctcaggggaggatgctgtgttc atctgtgaggtcacacagaccagggccaccgtccagtgggccaaagatgggaaggacatc aggaagagtgagaagtatgagatcagtaaagaggagagggtcatgaagttgaccgtccac agtgtcactgttcaggactctggggaatatagctgtgaggtcatcggaggggccactacc aaggccaagctggagatcaaagagccagtccacaagtttactaaggagctgaaggacagc gaggtggaggaggagggctcagtgaccctgcagtgtgagacggcccagcctgcctccaag gccacctggtccaaggagggcgtggagctgaaggccgggggacgctatgagatgagtcag aaggagaccgtcctcaccctcactatcaagcagctggaggagaaagacagcggcacttac acctgtgacgtgggcactgccacgatgatggcgaaggtgacagtcaaagccttgcctgcc agctttgaacaaaagctgaagaaccagcaggccaaggaaggggagagtgtcactctctgc tctgtgttatccaaacctggggccaaggttcagtggaagaaaggcactgagcatctcaaa gctggagacaaatatgagatgaaacaaaaagatgcctcctgcgagcttcagataaagcat ctgaatgttgaggacagtggggagtactcctgtgagtgtggagaccagaggaccacagcg actataaacgtcaatgcgttacctgtgaccttcaaacacaagctggagagccaggaggct gaggaggggggcagtgttaccctgcactgtgagctctctaaacctggagtccctgtggaa tggaggaagggaacacaggtgctgaagtctggagaaaagtaccagctgaagcagaaagaa tctgtgagtgaactcctgatcagcaaagcactaccagaggacagtggagactacagctgt gtgtgtggagaccagaagactacagccagcctcaagattaaggcccaacctgttacattc aaacaaaagctagggagccaggaggctgaggaggggggcaatgttaccctgcactgtgag ctctctaaacctggtgtccctgtggaatggaggaagggaacacaggtgctaaagtctgga gaaaagtaccagctgaagcagaaagaatctgtgagtgaactcctgatcagcaaagtagta ccagaggacagtggagactacagctgtgtgtgtggagaccagaagactacagccagtctc aagattaaggcccaacttgtgaccttcaaacacaaactggagagccaggaggctgaggag gggggcaatgttaccctgcactgtgagctctctaaacctggagtccctgtggaatggatg aagggaacacaggtgctaaagtctggagaaaagtaccagatgaagcagaaagaatctgtg agtgaactcctgatcagcaaagtagtaccagaggacagtggagactacagctgtgtgtgt ggagaccagaagactacagccagcctcgagattaaggcccaacctgttacattcaaacaa aagctagggagccaggaggctgaggaggggggcagtgttaccctgcactgtgagctctct aaacctggagtccctgtggaatggaggaagggaacacaggtgctgaagtctggagaaaag taccagctgaagcagaaagaatctgtgagtgaactcctgatcagcaaagtagtaccagag gacagtggagactacagctgtgtgtgtggagaccagaagactacagccagtctcaagatt aaggcccaacttgtgaccttcaaacacaaactggagagccaggaggctgaggaggggggc agtgttaccctgcactgtgagctctctaaacctggagtccctgtggaatggtggaaggga acacaggtgctgaagtctggagaaaagtaccagatgaagcagaaagaatctgtgagtgaa ctcctgatcagcaaagtactaccagaggacagtggagactacagctgtgtgtgtggagac cagaagactacagccagcctcgagattaaggctcaacctgttacattcaaacaaaagcta gggagccaggaggctgaggaggggggcagtgttaccctgcactgtgagctctctaaacct ggagtccctatggaatggatgaagggaacacaggtgctgaagtctggagaaaagtaccag ctgaagcagaaagaatctgtgagtgaactcctgatcagcaaagtagtaccagaggacagt ggagactacagctgtgtgtgtggagaccagaagactacagccagtctcaagattaaggcc caacttgtgaccttcaaacacaaactggagagccaggaggctgaggaggggggcaatgtt accctgcactgtgagctctctaaacctggagtccctgtggaatggaggaagggaacacag gtgctgaagtctggagaaaagtaccagatgaagcagaaagaatctgtgagtgaactcctg atcagcaaagtactaccagaggacagtggagactacagctgtgtgtgtggagaccagaag actacagccagtctcaaaattaaggctctcccagtcatattcaaacaagatctgcagagt caggaggctgaagaggggggcagtgttaccctgcactgtgagctctctaaacctggagtc cccgtggaatggaggaagggaacacaggtgctgaagtctggagaaaagtaccagatgaag cagaaagattgccgtgtggacctccaagtctgtgatttgaaacccggagacacaggaagc taccagtgcaggactggagacacagagagctcagcatgcctgaaagtcaatgctctccca gtcattttcacgaaagagctgcagagccaacaggctgaggaggggggcagtgttaccctg cactgtgagctttctaaacctggagtccctgtggaatggaggaagggggaggtgggtctt tgcctctgtgccaagtataacatcattcaggaagggcacagcgctaggctagtcatccaa aacctagacccagaagactcaggcagctacacctgtgacagtggtgaccggaaaaccaca gcacacctttctgtgaaggccctgcccgtttacttccaaactcgactacagaatctagag tgggacgcaggtgagatcgccatcctccgctgtgagatcaccaagcctggggccagcgtt gtctggagccggggcgacagggtcctggagtctaacaacaagtatcagctgaaacaggaa ggggccattgtgaagcttatcatctatagcctacaaggggctgactctggggagtatatc tgtgacacaggttaccagaagacctcctccgtgctcactgtacaggaggtggaggtgacc atagtgaaggtcttgaacagctgttcggtgcacgagggggaggatgtccactttgagtgc catctgtcccacgatgacgccaaggaggtccagtggaagcttgcggacgtccctctgcag aacaatgaaatgaacctgatccgtgcccagggcaaggtgcacagcctcaccctcaggggg gtcacgcaggccgactcgggcacagtcaccttcaccgtgggtcaccatacctccaccgca agcctgaccgtccgaggggcccctgtggtgttcaagaaggagctggagagccaggaagca gtggagggaggcagtgtttccctgacctgtgagatcagtgctgatggcaaggtgacctgg agaaggggctccgtgctcctcacccagggggagaagtattccatggagcacacaggttct acctacatcctgatggttcacaagttaaaggttgaagatgctggagagtacacctgcgat gccggggataagcagagcacagccaccctgacagtcaaagagtctgtgcgcatcactcgg gagctgcacgacatcacagtgaccaccgggcaggatgctgtctttgcgtgtgagttgtcc caggagggcgtgaccaacggagagtggtggctgggcgataacctcctccagaacaacgac ctgaaccagatggcctgccagggccgggtacaccggctgacactacagatggtcaccccc gatgaatcaggggacgtggcgtttgtggtgggcgaggagaagaccgttgcttgcctactg gtggaagagaagcccaaagccttaatccttgagaagcctcacgatacagtggccttggag ggcgagacagtcaccctatcctgcactgtctccgaccccacggccaccgtcacctggagc aggaatgatgtggccatcaatgcaggactcaagtacgacctgcggaagaatggagctctc ctacagctgcgcatccacaacctggagatggaggactctggaacttactgctgcgatacc ggggatgcacagtgcaccgtcaccttgattgtggaaggtgccccggcattctttcagaag gagctgaagaaccaggaagcccaggagggtgatgatatcactctgcactgtgagctctcc aaggcgggcactcacgtggagtggaggaagggaggcgcagtcctccaggctggtaagaag tacgagatgaggcaggagggctgcgttcaggagctccacattcgcaacctggagccagag gacaacggctactacacctgtgatgctggagaccagctcaccacggcattagtggcagtg caagaacccacagtagaggtggtgagcgagatgcaggacctccgtgtggccgaggaccag ccggctgagttcatctgccagtactcccggccggtccaggcccagtggaaaagaaacggg cggccgttgcagcctgacggcaggagggtggtagtggagcagaactggaccatggctcgc ttgtacattagccacgtgtccactgaggacagggggacgtactcctgtgaggcagagggg acctgcgtggtcgcctccctggaggtggaagccaaacccattgaaatcctccagggcctg gagaacatggacaccatcgacggcggcgaggccctgttcgagtgctcgatctctcgttgc gagatcaaagacagctgctggctcattgacggcaagccggtgaaggattcgccaaccact gagattgtgtccttcgagagtggccgccgccacctgctgctgctaaaggacctgcacgtc ggggacaactgcaaagtgaccttccaggcgggcaccgcagcgacctccgccatgctcaac gtcaaaggctggcagctggatgtggtgagcggtctggaggataaggtagctgtggtggga gagaaagtagagttcagctgcgtgctgaccgagcctgtgcctgaggcggaggtagcctgg tactctaacggagccgagctaaagaaggataatacctgggccatgcaggctgacggttgc ttctaccaactggtgctgagacaggccccagccatgccaccacaggagatcacctttgct gccagggacgccatatccatggccaagctcactgtcattacctttccagaccccccggag gacccagagctggtcagtaagcataaacagggggtgaccctgtcctggttcacacctctc agcgatggaggcagccccattctgggttacagggtggagatgaggctggtggacagcgcc ctctggcttccgtgccatgcagagcctgtgtgtaacacagagttctctgtggataacctc atcccagggagcggctacaggttcagggtggcagccatcaacagagctgggactggagaa ccagtccagctgcctcagaccgttcagctggaggctccgatcacagtgacccagcagttg gcctgtccaagcttgcaggagggtaagatggcccgtgtagagtgccagctctctgctgag ggcagctcggtcacctggcttagagacaacaaggagctggagtttgggctcaaataccag gtcaccatcgagggcaagacacaagtgctgctgatcaaagactttgagtctgctgaccag ggcgtgtacacctgtgtagcctcagacgaggcagaaagctccattaatctcaatttacca acaggtggagatggggttaagttggagggggcccagcccagcctgcctcctgaggctgcc tccgagggtgatgtccacgcgctgtgggaggccctggccaagaaacgccgcatgagccga gagcccaccctcgactccatctctgagctgcctgatgaggaggacaaggagcccaaaaca cccaaggagccagtcaaggagaagaaatccccagagaaggtgaacgaaaaggaaaaggag aaggttgtggatcctgtcatcatcgcaaagaaggagttggatacaaatctacacaccagc tctgaggatgagtccagggttccaacgctggtgtcctacctgaagaagagcagcaagtcc tccctctctgcatccaaccagacagagtccatctcaactgagaagttctatgtacagacc tcagtgcaacagacctcagtgcaacagaccacagtcctacagacctcatcttcaggacag cagatcacagcacagaccacagagatcactgggtgtggaaatgaggaggatgaagaaaag ggtctgctggatgctgctgtcaagatccaggctgcgttcaagggctacaagtcctgcaag gacacgtgtccagtcttcaaggacgtcttcaaggaccagaccaaggagcccaatggcacc atccacctggagtgtgtggttgagagaaagcccgacaaggtgcgctggctgaaggacggc gagccccttgtggacagcaaacaccaccacatcgacatctacaacgatggcacctgctct ctggtaatcaccgccgttaccaccaaggacacgggcatctacacatgtgaggttaccaac aagttcggcgtgaccatccacagcggcaaggtgacagtaggctcggcacgggaggcatct ggaaggaggcccctgaccatgggctacagcgccgacagcgaggcggagagctcgtctgca gaaagcgagatggacgagtctttgagacaggccagcaaacggctgcgccgcctcctccgc acacggctgccggccacgtcggaggaggagtcgttcgtcagctgtgacgaggaggctgag ctgaaggcccccgagcccaaatcgtaccgtgaggacgagcgctacctctacatccgcttt gacacgcggtctgaggcccaggtggcatcgctgcactttcaggagatgttcacggcccag gggatgcctgtggagaccaccatccaggaggctggacctctcaaagtggagctgcgcatc atgaagatgggatacacccaagatggctctgcaacacccacacaggagaagcagctgccc gcgttcatgacaggagcccccgcggccccagtcttcctgaccgaactccagagccaggac gtgtctgaaggttacccggtcagctttgactgcgtggtgatcggaaagcctacacccagc atgcgttggttcaaggacgggaagctcctggaggagaatgaccactacatgatcaacgag gaacacgagggctgccaccagctcatcatcaccaccgtgctgccttctgacatgggcgtc taccgctgcatggccgagaacaccagtggcatcgctgccactaaggctgagctcagggtt gacatgtcttgcagctcagactacgatactgcagctgatgccactgagacaggctcctac atcagcgccaagggctacatgtctagggaaactgaagcgtttgagtctatggcagaggat gagcagataccacaagtactggatgagctccatgatgtgcacgtcagcccaggctcaccc atcgctaagatgcagctgaaagtcaaaggtttggcctgtttccccgcgcccagagtgtac tggttcaaggacggtatcccactgcgttcctcagacaggatcctgctgctggacaagaga gacgtccacagtctggaggtcctggaggtgaagagggaggatgcaggagagtactctgcc tacatcagcaacgctgctggatcagcatactcctctgctaggatactggttctgggtcca ggagagctcacgcctgtagaagagcacgatcccaaggtgcctccggtgccgccacgcttc ctggagaagtttagcaacaggaaggtgaaacagggagccagtgtcaccctgtcagtcaga gtggaaggttctcccatccccatggtgacgtggctgaaagaggattctgctgaggacgtg ttgtggatcaagccagacactaagggatataaggtggccaggtctgggcgccaacacagc ctcatcctcatggatgcgggttctgagcacgccggcacctacacctgcatagccaccaac agggccggccagtccatctgcaccgcccactttgaagtagaggatgcgccacggccaaag gaagagaccaaaatccctctgggtattactatcagccctccagtggaggatgctggcaga agaatgccttatctaggtgaagttggaacagaagagtttcttatgaaactcacctctcag atcacagagatggtatctgccaagatcagccaagacagcgcacagaaccatcaagtgctc cagtggattgaagcatggcccaaagcctccacctcactacgtgtcccgggaggcgatagc gacgatgagaccaaaacaccctccgcctcgccccatcacggccgctctcgccccagctcc attctcgcagactcctcctctgagtctgacgaccctgatgccaggggagagatgtttgac atctatgtggctacggctgactacaaccccaccatccccaacaaagagaccatttccctg aaggagggccagtatgtggaggttctggactcggcacatccactcaaatggctggtccgg accaaaccaaccaaaaccaccccatcccgccagggctgggtgtcacctgcctacctggac aagaaactcaagctatctgctgatgctggcgatgtcccagagacaggtggagaagaggtc tcagaaggagagtacaaaagaagactactccaactgatccaggacatgatcaacagcgag gcagagtttgtcaaagagatggacttcttcacctcccaccacgtcaagcaggttgagagc cctgacgccccatctgacgtcaccagccagaaggaggccatcttcaggaacatccacgag atcaaggccttccatagcgagttcatgttccctaagttgcgcgagtgcgacactgatgac gacgtggccatgcgcttcctgaggagcggggagggctttgagaaatacctccagtacctc gtaggccagcaaaaggcagaggccgctatcagtgacaagaccgtacaccacttcttcaag aagtacacagacaaacagcaggccagtgccgaccctgctgaagggcctgtattgagcatt aatgcctacctacagaaacccctggacagaatccagaagtacaaggcctcactcaaggag ctgatcaggaacaaggcccggaacggtcagaactgctgcctgctggaggaggcctatgcc atggtttcatcactgcctcagcgttcagagaacacacaccacgtctccatgatagagaac taccctgccactctggatgtattgggggagcccatcagacagggacccttcatgatgtgg gagggtgcacctggggtaaggtcctcctccagaggccaccgtcgacacgcgttcctcttc aaaaactatgtcgtcatctgcaaatccaagagagactccaacacagacacccagggctac gtctttaagaacatgatgaagctgaacaacatagacgtgaatgagacagtggagggtgac gaccgggcctttgagatttggcacgagcgcgaggactctgtcaggaagtacacgcttcag gctcgcaccgtcatcatcaagaactcctggctgcgagacctcagggacctgcagcagcgc tataccatgcccggctggagtatgcctgactttgatgagcttctggctgactgcacagtg gagctgggacagacagtgaaactggcctgcaaggttactggagtacccaaacctgtggtc acctggtacaaggatgggcatgcggtggaggccgaccctcaccacatcatcatcgaggac cctgacggttcctgcaccctgatcctggacaacatgacagcggatgactctggacagtac atgtgcttcgccactagcaccgcaggcaatgccagcaccctggggaagatcactgtccaa gtgcctcctcgttttgtgaacaagatgaggaatgctgtctttactgttggtgaggatgct cagttctcctgcaccattcagagcgctcccagccccaagatcaggtggttcaaggagggc aggttgctgactgaccaggagaagtatcagacctacagtgagtcccgtagtggagtactg gtcctagtcattaaaggccctacggagagagacctgggacattacgaatgtgagttgtct aatcgactgggcagtgctaggtgtgcagctgatctgtgccttccttctgctgtgactagg agaggagagcaggcgatcaccatcgaagtcaccgagcaggagactaaaataccaaagaaa accatcatcatagaggagaccataaccacggtggtgaagaacacccgtatgaagcgtcgt ggcctgtctccatctgggttcaaccgctcccaaacctccaccccagatcaccagaccacc cccacggccaggcagaggaggcaggcttccaccaacaggaagaccaccatccccaccctg tatgtcacggagcccgagggggccgcaggggcccgggctgcggagaacaagtgggtggag gtagaggaaattattgagtacaaggtcaacaagtcgcccaggccctctaggagaggtatc tccccagccgggtcggagcgggcacacaccccctcctccacccggccacagaggtccgca aaccctaacgccaacaactccaacaacaaccttgtagaactgcagaaccactccgagcta cagggggcacagcctctgtactgggacgatgaggaggaggatggtgacgtggctgtggat gggtccgaggtcgcccctggaatacgtggagaggcctacgaggtctcctcgcttctaatt cctaacgaccatgaacacgaagaggatgaggcctggctagaagagcagcaagaggctttc atcacagaaccggatgacgatgacaacacacccagaaagctggagcctaaaatcctgacc gagggcagtcgcgttctcactctggaggacctggaggactacgtccccagggagggggag accttcggctcctccaacacccgttcatcacctcccgagaggccctgcgagatctcagtg ctccagagggagattgggggctctgctgtgggccagccggtgctgctcaacgtagggagg cctgtggggatgcctagggagaggcccaggccaggcttcttcagccgctttagagatcac ctctcaggaagcatgttctccccggccggcccccaccacaactacaaccaccaccccagc ggaggtcagtccaggagggagattcccatccaggtcagccacgccaagctagaggtcaag ccgttgtactgctctgaggtgcagagagtggagggagtgcagcagagctacaaaactaaa gtctacacatcagtgggcaagtcagtcactcttcagattagcaagaataacccatatcaa aaccaataa

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