Oryzias latipes (Japanese medaka): 101155851
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Entry
101155851 CDS
T02443
Symbol
tyk2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
ola
Oryzias latipes (Japanese medaka)
Pathway
ola04217
Necroptosis
ola04620
Toll-like receptor signaling pathway
ola04621
NOD-like receptor signaling pathway
ola05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
ola00001
]
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
101155851 (tyk2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
101155851 (tyk2)
04621 NOD-like receptor signaling pathway
101155851 (tyk2)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
101155851 (tyk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ola01001
]
101155851 (tyk2)
Enzymes [BR:
ola01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
101155851 (tyk2)
Protein kinases [BR:
ola01001
]
Non-receptor tyrosine kinases
JAK family [OT]
101155851 (tyk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
Jak1_Phl
SH2_1
Kinase-like
Kdo
SH2
ABC1
FERM_C_FAK1
Motif
Other DBs
NCBI-GeneID:
101155851
NCBI-ProteinID:
XP_004071399
UniProt:
H2LLN7
LinkDB
All DBs
Position
8:complement(8372331..8381259)
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AA seq
1169 aa
AA seq
DB search
MLRRRWSKFFRQETCPGPGEAPQTPGIHVYLFWSRDGGTHLSHTSGDVTAEELCIRAAEV
VGINPLCHVLFALYNPQTRYWYSPNHIFSPEENCSLLVQYCMRFYFPNWHGLNDKVPLVT
RHSLKGGANQKGSTLLDITSLEYLFAQAKHEFVNEVVEMKEVQNEEERSQFKNESLGMAV
LHLSHLAIETNSTLPAVARKVSFLQCIPRSFAKNISNDNFLTKIRIRTVFAEFVRSFQQH
TVDSRKVTPQEIMYKYISTLEQLAPRFGTETFQVISLKLREDGDGSSSYSNVVHGDSLSK
GNSNPLITHEVMVSGIEGLKWRKVHVHKAQVNSYLRNDYLNYKKAKQQSKQLNTPDTWSL
FSDFPDITHIAISDANVYISTLDNRCMVVQMSSSQEARSFVSLLDGYYRLTADAHHYLCR
EVAPPRVILSEANLLHGPMHEEFVLHKLKKDAAEEGVFLVRWSAVDYHSIILAVLKRNEN
GSAPSHKQFRIQQKGSVFCMEGWDREFSSVKEFIDNLKTFVLKSGSDSFTVKKCLLPKQA
EISNLLVKRHKDGLYPLSESFSQKLTKLRFNRIKEKNITPEVHLGRGTRTNIYSGRLLVG
GEDDGNDVEFNNNSSKQKGIRVVLKILDRSHEDIALAFFETASLMSKVSHSHLVFVHGVS
VKGSENIMVEEFVEFGPLDVFLRKHKAAVNAKWKFIVSIQLASALSYLEAKQLVHGNVCA
KNILVARRGLERDTTPFIKLSDPGISLNALTREERLDRIPWIAPECVDGSAPIGNTADQW
SFGITLLEICNNGEVPISGCTLPEKELFYRERHHLTEPSSEELAKFISMCLTYEPEERPS
FRAVLRELTEMMMKNLDIPDTESLSPPVPSTYQKRYLKKIMDLGEGHFGKVTLYKYDPTN
DDTGELVAVKVLKQESGCVAEGLMKEIEILKSLDHINIVKYKGCCTEPGRTEVQLIMEYL
PMGSLRDYLPKTKVSVCQCLMYAQQICQGMDYLHSKRYVHRDLAARNVLVENNSLVKIGD
FGLTKHIPEGEIYYRVREDGDSPVFWYAIECLKESKFSFASDVWSFGVTLYEILTRCDNR
QSPPTKFYEMMGEAQGQITTMIIIDLLMKNMRLPCPRDCPHEVRLLMEQCWHKDQAQRPS
FENLIVRFEAIRRTYDWQFNSNFTMSEIC
NT seq
3510 nt
NT seq
+upstream
nt +downstream
nt
atgttgaggagaaggtggtccaagttcttcaggcaagaaacctgcccaggtcctggagag
gctccccagactccaggcatccatgtttacctgttctggagcagagatggaggaactcac
ttgtcacacacaagtggagatgtcacggcggaggagctgtgtatcagggctgcagaggtt
gtaggtataaacccgctttgccatgtgttatttgcattatataacccacaaacacgctat
tggtacagcccaaaccacattttcagcccagaagaaaactgcagcttgctggttcagtac
tgcatgaggttctactttccgaattggcatgggctaaacgacaaggtgccactggtgacc
cgccactctttgaaaggtggtgcaaatcagaaaggttccacactgctcgatatcacatcc
ctggagtatttatttgctcaggctaaacatgaatttgtaaacgaagtggttgaaatgaaa
gaagtccagaatgaggaagaaagaagtcaattcaaaaacgagagcctgggaatggccgtg
cttcacctgtcacatcttgcaatagagacgaactctactttaccagcagtagctagaaaa
gtcagtttcctccagtgcattccaagatctttcgctaaaaacatctccaatgacaacttc
cttactaaaattaggatccgaacggtgtttgccgaattcgtgcgctccttccagcagcac
acagtagacagccgaaaggtgaccccccaggagatcatgtacaagtacatttctactctg
gaacaactggctccacgatttggtacagagactttccaagtaattagcctgaagctgagg
gaggacggcgacggaagcagctcctactcaaatgtggtccatggagatagtctctcaaag
ggaaacagcaaccctctcatcacacacgaagtaatggtgtctgggattgaggggctaaag
tggaggaaggtgcacgttcacaaggctcaggtgaattcctacctcagaaatgactatttg
aactacaagaaagcaaagcagcagtcgaagcagctgaacactcccgacacatggagccta
ttttctgatttccctgatataacccacatcgccatttctgatgctaatgtgtacattagc
actctggataaccgctgcatggtggtacagatgagctccagccaggaggcccgttccttc
gtctctcttctcgatggatactaccgactgactgcagacgcccaccactatctttgtcgt
gaagtggctcccccaagggtaattctgagtgaagcaaatctcttgcacggacctatgcat
gaggagtttgtgctccacaagctgaaaaaggatgcagcagaggagggagtgttcctcgtt
cgttggagtgcagttgactatcacagcatcattctcgctgtgctaaaaagaaatgagaac
ggttcggcgccaagccacaagcagttccgtatccagcagaagggttcggtgttttgcatg
gagggctgggacagagagttctccagtgtgaaagagttcatcgataacctcaaaaccttt
gtgctaaagtctggctctgacagcttcactgtcaaaaagtgccttttgcctaaacaagca
gagatttccaaccttctggtaaaaaggcacaaggatgggctctaccccctctcagagtcc
ttctcccagaagctgaccaagctacgctttaaccgcatcaaggagaaaaacatcactccg
gaggtgcatttgggtcgaggcactagaactaatatctactctggacggctgcttgtggga
ggggaagacgatggcaacgacgttgagttcaacaacaactcttctaagcaaaaaggcatt
cgagtggttctcaagatcttggatcgaagccacgaagatattgctcttgcatttttcgaa
actgcaagtctcatgagcaaagtgtcccacagtcacctggtgtttgtgcacggcgtgtct
gtcaaaggatctgaaaacatcatggtggaggagtttgtggagtttggacctttggatgtc
ttccttcgcaaacataaagcagctgtgaatgctaaatggaagtttatagtgtcaatacaa
ctcgccagtgccctcagttaccttgaggctaaacagctggttcatggaaatgtctgtgcc
aagaacattctggtggcaagacgtggcctggagcgcgacactactcctttcatcaagctg
agtgatcccggaatttccctgaatgccctcacacgagaagagcgtttggaccgcattcca
tggattgcccctgagtgtgtggacggcagcgcacccatcggtaacactgctgaccagtgg
agctttggcattacgttgctggaaatctgtaacaatggggaagttcctattagcggctgc
acattgcctgaaaaagagctcttctatcgagaaaggcaccaccttactgaaccatcctca
gaagaactagccaagttcatcagcatgtgtttgacctatgagccagaggagagaccttct
ttccgcgccgtcctcagagaacttacagaaatgatgatgaaaaatctcgacatacccgac
acagaaagtctgtcgccaccggtcccgagtacataccagaaacgctacctaaaaaagatc
atggacttgggcgagggtcattttgggaaagtgactctctacaagtatgacccgacaaac
gatgacacaggagaacttgtggcagtgaaggtcttgaaacaggaaagtggctgtgtggct
gaagggttgatgaaagagattgaaatcctgaagtcccttgatcacattaatattgttaag
tacaagggctgttgcactgagccaggcaggacggaggtacagctgataatggagtacctt
ccaatgggaagcttgcgagattaccttcccaaaactaaagtgtctgtgtgccagtgcctt
atgtacgctcagcagatctgtcagggaatggattacttgcactccaaacgctacgtgcat
cgagatctggctgcccgcaacgtcttggtggaaaacaacagcttggtcaagattggtgac
tttggcctgacgaaacacatccctgagggggagatctactaccgggttcgagaagacggg
gacagtccagtgttctggtatgccattgagtgcttgaaagagtccaagttctcctttgcc
tcggatgtttggtccttcggtgtaacactatacgagatcttgacccgctgtgacaaccgg
cagagcccaccaacaaaattctatgaaatgatgggtgaagcccaaggacagattacaaca
atgataatcatcgatctgctgatgaagaacatgagactgccttgccccagagactgccct
cacgaggtacggctgttgatggagcagtgttggcataaagatcaagcacaacggccctca
tttgaaaacctgatcgtaaggtttgaagccatccgcagaacctacgactggcagtttaac
tccaacttcaccatgtctgagatttgctga
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