Oryzias latipes (Japanese medaka): 101164701 Help Entry 101164701         CDS       T02443                                  Name (RefSeq) nesprin-1-like isoform X1   KO K19326   nesprin-1 Organism ola  Oryzias latipes (Japanese medaka) Pathway ola04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:ola00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     101164701  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:ola03036]     101164701 Chromosome and associated proteins [BR:ola03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     101164701 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Spectrin Spectrin_SYNE1 CH SYNE1 KASH Motif Other DBs NCBI-GeneID:  101164701 NCBI-ProteinID:  XP_023807343 LinkDB All DBs Position 22:305421..413618 Genome browser AA seq 8779 aa AA seqDB search MAHYVDPAVRKTSINLVTGFCQYLRDEQEAVQKRTFTKWINSHLEKHKLRLEMNDLFEDI KDGVKLLALLEVLSGQRLPCEQGRHLKRIHWVSNISTALKFLEGRKIKLVNIHATDVADG RPSIVLGLIWTIILYFQIEELTSNLPALQAFSNSSSSVDSLTSSETGSPPVKRKVLHKFQ GNAKKVLLRWVQCTAAKHHGIEVKDFGPSWRDGVAFQSMVHAIRPDLVDMEEVRRRSNRE NLEEAFSLAENELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPNPGPAAGQQEYGPQ DIELMLEREERKMLRELKVFLDQLEKDVLRAQGSDGNLSDKYQVFKHFHVQFEMKKKQAE PLLQPVHPDGKLSVDQALVKQAWDHVSARLLDWHIHLDKSLPGPLGSIGAWLHRAEMALR EDFPLHHAPEETANVLHRKLQQHQDVLKNLEVHRRTFQQIHKDRSVHGVPVPPEQLQDMA ERFNFVSAHSHSHLIQLEFWEMKYRLTAFLLLAESKLKSWIIKYGRRDSVELLLRSYLTF TEGQRFFEQYEVLFTALQRAAEVYVKSDSAADEAEGVSKFLADATVQWKNLALEVRSVRS MLEEVICNWEKYGSTVAALQAWLEDAEQVLGQSENIKRDFFRNLSHWIQQHMDMNDAGNF LIETCDETVSRDLKQQLLLLNGRWRELFIKVKHYGRADEVDKLRQDYQDAMNTLKLFLDA TDVKMTAPVQVSFLNVRAFVQDVEEIKQKVPAMEAACRAAGRTAQLLSKDAPQEELLQMT AVMASIKEQLSKIREGCLPLLREAQALLPPLEEMEKNITGFYQALEKASCITGAGRPGGP ADFRQQCQELATLTHSCKKCLTVIERTHQNIQRSLSSSGALQHLDLALLQKRVAELQTAS QNMIRESTEWRRQEETNSSLLRRFEESRVELEKVLKAAQSCVTESGEPEDLLRKHTDFFE QLDQRVLNTFLKACDELTDILPEQEQQALQETVRKLHKRWKDMQTDAPLHLLHVQVEAER SRLELSMQECKAELTRENRHLVGVGSERLLKEHRSFFGEKGPLSQCEKRLQLMEELCQKL PEEDPAHRSLQSARKELGELQEEIQSTRLKLLQHQDKWKDYNKRYAELSCWLISKESQLR LLRNRASDHRKYGQVKTAIAELRNEAELQEGNLGWLNARMADLIEVSADDDAQRQGAALT KLSADLKGLVASLSEAEKMLLTVGDCVQFREEVQATLEDLAQGQKEVQAEASQILDSSDP REAQQLLLVHQQHLKRLRMKRKEVQQLFSRGQQLQVEEALEGALQQDLQTLENSLSRMEQ STDSQEQSLEVTLAAWQQHSDQQEAVQTFVLRARSSMDRELNFSSPESLEVELDQARVLL KQSEGEALHTKTLSKRAAEIQLSPKNKTLLLQQAHSLREQVEEVEESLKQDVKLLEDMKL QWDTFTAGFEGLSQWISETEKQLEDVRTSAPPVEEQRRTVQEVRRGLQERAEVLPQLEAD SASLARFVSSGEAARIKARLTQIGRYWEELKESVQQLDGLLQERWRQQQKFSSSLEELQA GLQELQAELNRPMGGCSSSSETFRALQSHTDVCQALQQLKAPLLALSASARRLGDDGPAE RTVTELSAALEQALQEAKVRQGRLESLLSSWQRFEKQLSNFTSCLERIESSSRPEGPCLT ADKSKLRFEIQDLQALQPELRSLQTAHADLQTLGMDFYHSAPEQKVLQMKDELETLHRRL RVQQEALPERISDLQNHLCQLERLDGTLLEFARWSERMLSDLHSAPQIRISSLQATVEHT KETQKALLEQSSVRESLEQQVQELCRLCEPADAQLLTSRADSCLQPQREALQTAQLQVDC LQKLAAFLQTHSTVAGVLQGLRHTVESAGSWDCARVEELQLELSAIVADIHQLETAAVSL DSSLCKAHLYLSSEDGKSCRMLADALSADLDGVRNLLGTKQNEAEALGALWTSFRQRKDQ LLRAVEDIEEKAEKQTLKEASLQGLQLRLRLFNQLEDELQAHQHEEQWLQDKAEQLARRD AELAGEVLREMGLLRSTWEAARRLIADKQEQCSVLTELMREYQTLKARVCHVTGRAEPLA DLSSLLRDAEETKRALAKHESMKAEMSSRHADLDQFSCKGKQLLVELKKIPECDSQPIKQ DMDAIVDQWLDMSEKMDLNVDLLIRVLGLWEDVRNISEDVESWTSSSTAELNQSLSNFSD SRKVSARLAELQEEMSEKEQKLEALQIKVSELKKSSQSQETPAKLQVLENDLQEKIGAVK KLHQQSAANLMDFSSQRRQLQDYITQMSAWLRSMEESLGSSPTGLDPEDICRVKDLQKEL QNQQGSIDTTREGLNNLCRKYPSEELAGLGSSLTDLIKTYDSVSQMSARTLASLQSGLQQ QFLRLVQEFHLWLSEQRDIVKECSDRSGDTQTVERKLQKLKGAMDRVEEGESRLTQVCEE GEKLLLHLPKASAAQVQQHLSSIQQDWDGFVEQCRQNQQILEDSASLMRGFEGRLEKLRR WLEQMESRVTSDQLEVKQHGSEKALLELVEEYQQEVLRERDSFERLCQEGQALNEGGRGD GGETRVSAQLQSQHQALLRRIRERLRCCQLTLQEQQAFQETLQSSWSWLSGVQERLDSLS STIGTKETLEKRLGLVQDILLLKGEGEVKLNMTAGKGEQVLKHSSLETQEKIHTQLQSLK DAWANLLMTAISCHSRLEWTVSQWSSFQEDRSQLLQWMESVEKELGMVLLQQPGLKEKSA LLERVRSIQANVDAHAGILSRLTEKAAEMHEKTGDQTFGPESRVELNARFADVSAVVKGK VRSLQNIVSEHEQYVDAVRDFNDWLITAKEELQRWSDLSGDSVSIRRKLCKVQELLDSKQ RGRERLSRIQRFGAVTRDNTGSGGYEALEREEAALLSSYEQWERTALQTRTSLETALSQI SNSEQEFGSMTAQLEQDLLDFSDQLKDWRLRLVQVERHGDGEESATAWRAAKDCWEELVK AEATCDHLKAQLNDLCRFSREISSQSERVSSLIKDYNSLSLQASRECQSRERQLDHSFRS VFRDFQQWLVNAKITTAKCFDEPQNVSEASSSLQKIQDFLSQRDTGESKLNTVLVSAERL FAVAAKDTRDAVRAKSNVARDDWKSFMSNLHSREAGLQDLLSQMKDFEANATPFQEKLNA TELVVQESSSRLHDLTAKREELQKLQSVLDDLASLEIQLCRLREKARLLMDQYAAGKGFV HRVSQLSAQLLALTTLTKEKTSRIDRIVAEHQLFSQGLQELQSWVADTTHMLQNYCAPTT DKSVLDSRMIKLEALLTARQEKEIQLKMLITRGESVQRNTSAEGVPALQTQMQELKDSWD ALHSASILCKSRLESALSQWTSYQEDLRQFTSWVERMQENLDAVGKPCPEMRDKSAHLSR AKLLLEEVLNHQTLLETIAAKSAGMGENYATQLELQELEEQYGAVRDRASRAVSRAEELL KAHQEHQRALHAFQDWLVQQQETLGSYTQLEGDVDALEETLQKLQEMLLNLRWSPPQELQ LCCTEGQALLNAVQLSRELVLPSGAPQTEDRALEGLQQEWRLYQARLAETRAQLNGTLAR LRQMEQKFQRLDSWLKGMESKADVRSHRRSERATKEAQLQMIKSWQEEVLVYQEEMEGLS LLAQQVLDETHISSRISTRATQITARYHALVLHLLETIRQLQEEVSCMEEAQSASSTFSD WLGAALSSFSSAASSVQVDRCAMERKMKKLEALQADMEQGHAYLKALRERAERAILFLEG PEAEQLTEEVDAHVLQLQELQGALRVEHCSLEKCMCLSKDFTEKHKAQAQWVKETRNLLA SSVEPKAELYQKKAQLAKYKTIQQVVLSQESTVKCVLNKGEALLEVISDPSVSDSMERLQ ADYLELCTAAQTQVESLAEWVKEHEDYNTELQEAEKWLLQMSSRLVTSDSMQTSSMESTT QQLARHKAVMEEISSFEERLSTLKQKGESLFSGCSDQVQAKMSQQVQTQLQGTRDSYSAV CSTAQRIFQSLDRELQKHVSHQDALQQCQAWLCGVQEELQHQAPSGLQEALKQVKQYRAL QEQASTYLDLVCSLCDLTDEAVRRAAAQVQQVKLTIEERMSTTQELSQAWRELKEQKQDL SSSFQDTEQQLLSLCRRPAELEMKIAQNVLAQAEECCLQLQTKQNVFTKMTETVDRLTGG QTSPEHADLDRLSRCWVALRHQAEKLQAQKEEDLQRAGGYHACIAAVEALFEEVSGVWDN LARTDAESSSQHLEALRKLAGTLEERKAVLEELKEQKQKVIQHLNLDDKELVKEQVSHFE QRWAQTQNLIDRKVRDSMVTLEDMSQVEARLREARDWAEEQQPALSEAMKMSPPPELAQS FLFDHLSICSELEAKQLLLAQAVADADRVLPRLGLSERHNLQQMIADTQAEVEALSGKVV QRRKHLSKAFTERTQFLMAVGQSIAWVQQNEKKAQEEEYIALLAEDVSKQVRSCRNIQSS LKAYRSELTSLWSQGRDLMREASEEERSELLAKLQELQSIFDRTLHRCGQKLQELEKVLV SRKYFKADLERICLWLKQADIVTFPETNLMVGGAELEVQLHKYEQIMEQAVENEELLLAV QRAGQEVLPTLNEVDHCYLDEKLNSLPQQYNSILALAKEKREKIQQAILTRKEYSSFIDV THKALKELEEQFSSLGTQPVGLETKEVLSLQSQYKAILVDLSTLGLAVSELNQKKEGFRS TGQPWRPDEMTQLVSLYNGLKRLVEQKVEHLDETLESFEDHKAMAMQMDSELRATKEQLD KVNTETQSAEERLKNYHTLAGSLQSADSHLSRLMEQMNSLAPRVDRAAHDASKEQVVLWQ EELRSLQAAVGELIEECETRFVHSKDFQTEMEKSLEWLQQIRRELDCAVIVDVRVEKVQE EIRKQQIMQEEVQSRLRIVAALSSREKQKYTSANELVPAHVNRRLEEMTKLQADVQRALT AKQITLEEALLLCQKYHFRMQAACEWLEDAVSFLQQASLGVDVENHEECLRQQADIVATE QEFLIHLEELQSLLPKLETLVNPTAKEQLRLSVESAQQRGVEVRDQLQCHKDVLHSCVAQ WTSFQEARQTVIELMNEAEKKLTQFSTAKAATSQEAEDRLSSHRTLVSLVSGFQEKLSSL EEQATQLELVGSDASKATISRSMTTVWQRWTRLRSVARGQERVLEDTAQEWGTFREKMLK VRSVSEDLQSRFPDSAVEKASKATLQSLLDQHDLLSQDLERELSALMLLRQYALSLLHAV EVPSPTNDHEELPSLKEIREVQDHMESLLTQSRTKRAHVAQELREREEVEKELSVVKVWI QQSRELLLNPTQDIESLLHQLEVLHEEVISFRQNVEKLAEQQQSKYLDLYTILPSEISMQ LAEVSLALAAIEDQVLSKERDIQKTREIKEDFSSRIQDMSEKLKTISSKFNEKSPDVEHA KEEVKRLFEDLDGCGSALSELDASLQDFSRSNPLLAKQLSEAVSKLSEMHHHTSRLADCR NNWLKKAVCYLDEYNEMLDFIVRWADKARSLVRANIIWNSSVHLQEQIRIHQAVLRESRE LHGDLESMAEKVELLSEVLQVQALSQQVCELSRHTDELQQSIRTQLQSLQDANKSMETLE REVKALHVALEQLQAVLTSPEVTRQSLKEQLLQRQRLLADMEGLKVQVQAVQRCQSTLQV PEDVMPSLAVCHTALRLQHEASQLQHVAIQQCNILQEAVVQYEQYEQEVGELQGLIEEAH QVIQDRPVPSSNIQELQAQILHHEELAQKIKGYQEQIASLNSKCKMLAVKAKHATMLLTV SDAHGLPAELQDEVGGEVRKSAVTMTAGRCHTLLSPVSEESGEEGASSEVCSPLVGGSSP VTPPQDADSKEGQGRLTRAAVLDMYDPTSESVAHLDELQRSWESLKNVISEKQRSLYEAL EKHQQYQSSLQSISSKMETLEDKLSEPLELQKSPESHMKAHQGLLTEIQDVQEEMERLQS SFTQDVSAAVDSDVSEQLAMQSSLSVLGERMSTIHMKASGKHQQLEEHLSERQEVQHQER VLQGCWLQAEELQEWLSQMHQGAALILLPHAAGEVDEQLYKCQGVLLEVEEKVSALSELS MRSDSLLLESPAHTREEAQRLASRLQALKGGLLELQRMLQDKQTSIQTSLQEPEDSGSDS SLSQSSSVQDWLAQARTTRSQQHEDSLQRQRELEEQLAEQKKLLQSVASRGEEILIQQAS PSSSSASLPSDSEAGLEQMRPRWRSLQLELKTKLQLLEGTLEQNQNQNQVPGAAAASGTA LRSPQVFPPASRVPAGELFSGPPAGNEPSLKTLYDAFRDTVRDAQPGDWGGALVAQMERQ LFSAVASTSFWLDGVESSVLSGSELLAETTRTLQQQETLQKDLSCVAEEVKLCESLLAGS SGLAEEDRTLLQDNLDCLQGRLSALGGALGQRCEHMRSRAQELALYQTDLQLLQTALMEK KRQLLQGAAGSTDRPACEQLEVLTSEEETLKDFELRIAELKSRGGDLQADQASTSNLLKL QDSYEDLVLIVASRRSGLNQNLAQKEQYERALQDLTDLLDTAKDKMSADGRVLAGSVEDV QTLLDKHKEFFQGLETHMVLTEAYFRKVSGLMLPTEGQALQETLAEAQRVLKEAHRRGVE LEWMVQVWSRLEQDYQGLSRQLEALEGRTPSAGLEEESEERLTDRISLYQGLEGGLAEHQ HKLHQLLDEGKHLLGGLSCPSLESRLAQLGKRWLDHAAKVKKERQRLEAVLKHWSRYQRA RADIGEWLQSALERLEFWNTQAVSVPQELETVRDHLSAFLEFSKEMEGKSSLKNAVVSEG NQLLRLKKVDTGVLRSELARIDAQWAELVTRIPVVQEKLHQIQMEKLASQHAISELFNWI SLMETVIEEDEENLKSAVGSNVIQDYLQRYKGFRVDVSCKQLTVDFVNQSVAHAGLQDPE SRHSEKTDFAERLGAMNRRWQILQGRLSEQIQLLENLLEMWLEYESSIQALKVWMNAQEE RLRRKPRLEDLTSVQNALKDCQELEELLKDKEKDLEKVEEQGCALVQNKTDEACAIVMET LQGVNHSWANLHHLTGQLKISLTSVLDQWSLYKQASEEINAYLMKGRYSVSRLRLLTGSL EAVQQQVQSLEELQEDLEKQESSVRRFGALTHQLLRDCHPSVSDSLNNSLKDMNARDKTA EPEPEAGGAVSALRWSGLQEEILERLQSSKALLQLWQRYKELHHQSCSGVQLQEEKADAL LKSSCSNDMADEELPRWIQGCSELLRSQAPLQASLEVLQTLGEQLKQQVDTSASSTLQSD HLCLRQRLRVVEQALRGQLTALQTGVQDYQTFKDQLETLSCWIREAEEDLRLQDPNGCTS LSVTQSRMEGLKELMLQFSSTAPELERLNELGYRLPLSDAEIKSLQNLNRTWTTASTQTT ERFSKLQAFLLQQQTFLEKCEAWMDFLLQTEDKLAVEISGNFLSLMEQQKAHELFQAEMF SRQQILHSIISDGQQMLEQGQVEDREEFGVKLALLSNQWQGVVRRAQQRRGIIDSLIRQW QRYKELLEKLSRWLQDVCPPAEAEGGRVPLQQARCRLEAVQLKEKLLQRQRGSFILTVEA GRQLLLSADGQAEAELQAQLTQVQERWREACSRLEDQRRRLAGVLKDWQKCEAGIATSLE KLRSFKKQLSQPLPDLHEELQAEQTRCQDLEKTSGGWTADLDHLTLLKEALTWSISAEDL SVLQERIELLHRQWEETRLQLSLRRQQVSKRLNEWTVFADKYKDMCEWLTNMESKVSQNG DISIEEMIDRLHKDYQEEISVAEKNKQQLHDLGERLARASQQNKAAEIQQKLGKVGDRWQ HLLDLIGARVKKLRETLVAVQQLDRNMSSLRSWLAHIESELSKPISYDSCDFTDIQRKLD LQQELQRDIEKHSTGVASVLNLCEVLLHDCDACANDAECDSIQQATRNLDRRWRSICAAS LERRLRIEETWRLWQKFLDDFTRFEEWLAPYEETAAQPNSSGVLYTEAKEELKKFEGFQR LVHEGLPQLELINKQYRRLARENRTDSSCRLRGMANSANQRWDDLQRRGAVIVRRLKHFI SQREDFETARDAILVWLTEMDLQLTNIEHFSECDIQAKTRQLRSFQQEISLTTARMEHIF QQGGALLEKSEPLDAAVIEEELEELQRYRQEVFGRVERYYKKLIHLPLADEDADASFSDR ELDEPGDLSGVPWNERSGDGFLSPLASSGRSASLAAQLRAEHSGRDTPASVDSIPLEWDH DYDLSRGLESAGRALREQQSEEEFLQPAPPGLSDVQVAENLEAFVRLTEQTLRSCTGEPP PLEAVDPTPTEQDPSYIGYMRLLGECRGRIDAAKRMGSELQEEGEVLSGLVDPSSSESQA SGVIERWELLQAQDLSKGRSSQQQQQLTSDLCSVCSWLEEAEADLQQQRGQGVTSDMQTI QHHIRKLKELQKAYDKRKPIVLSINLCSPDFLQPDLQDSQQLQVRLKDLNKHWDQLGVSL DEWRSSLQEALLQCQDFHEMSHGLLLWLENIDRRRNQALPIDADEDADGLQQRHDALTQI RQELLDSQLKVSSLQDVSLQLLLHSQGSGCSEAKEKVHVIGNRLKVLLKEVTHDLRELAK TLDMSSSQQDLSSWSSADDLDTSSSLSPASGRSTPSRQRSQRGDSSAPQPGACMSGPPLS RFRSAAGSGSSPSDDGQLPPRASRLRRVLWVALPLQLLLLLLLLLAFLLPLSEDYCAQSN TLAHSMYPMLSYTNGPPPV NT seq 26340 nt NT seq  +upstreamnt  +downstreamnt atggctcactatgtggaccctgcagtcaggaagacctccatcaacctggtgacgggcttc tgtcagtatctgcgcgatgagcaggaggccgtgcagaagagaactttcaccaaatggatc aactcccatctggaaaagcacaaactgcgtctggagatgaacgacctctttgaggacatc aaggatggcgtgaagctgctggctctgctggaggttctgtctggacaaagactaccctgt gaacaaggacggcacctgaagaggatccactgggtctccaacatcagcacggctctgaag ttcctggaaggtagaaagatcaaacttgtaaacattcacgccaccgacgtcgcagatgga cggccatccatcgtccttggtttgatctggaccatcatcctctacttccagatcgaggag ttaaccagcaacctgccagccctgcaggccttctccaacagcagctcttctgtggacagc ctcaccagctctgaaacaggaagtcctcccgtgaagaggaaggtccttcacaaattccag ggaaacgccaagaaggtcctgctccgatgggtgcagtgcacggccgccaagcatcatgga atcgaagtgaaagactttggtcccagctggcgtgacggggtcgcctttcagtccatggtg cacgccatcaggccagacctggtagacatggaggaggtgcggcggaggagcaacagggag aacttagaggaggccttctcattggcagagaatgagctgggaattcctcgactgctggat cctgaagacgtggacgtcgacaaaccggacgagaagtccatcatgacctacgtggctcag ttcctgaagcattacccaaatcctgggccggccgctggacagcaggagtacggtcctcag gatatagagctgatgctggagagagaagagaggaagatgttgagggagctgaaggtcttc ttggaccagctggagaaagacgtgctgagggcccagggatccgacggaaacctgtcagac aaataccaggtcttcaaacacttccacgtccagtttgagatgaagaagaagcaggcggag ccgctgctgcagcccgtccacccggatggaaaactgtctgtggaccaagctctggtcaaa caagcctgggaccacgtgtccgccaggctgctggactggcacatccatctggacaagtct ctgccgggccccctggggtccatcggagcctggctccacagagcagagatggctctgaga gaggacttccccctccaccacgctcctgaggagacggccaacgttcttcacaggaagctg cagcagcaccaggatgtgctgaagaacctggaggtgcacagacggaccttccagcagatc cacaaggacaggtccgtccacggggtgccggttcctccggagcagctccaagacatggca gagcggttcaactttgtgtcggcccattcacattctcacctgatacaactggaattctgg gaaatgaagtacaggctgacggcgttcctgctgctggctgagtccaagctgaagtcctgg atcataaagtacggccggcgggactcggtagagctcctgctgcgcagctacctgaccttc actgaaggccagaggttctttgagcagtacgaggttctcttcacggctctgcagcgggcg gcagaggtctacgtgaagtctgacagcgcagcagatgaagctgagggagtcagcaagttc ctggcagacgccacggtccagtggaagaacctggcgttggaggtgcggagcgtccgcagc atgctggaggaggtgatctgtaactgggagaagtacggcagcacggtggcggcgctgcag gcctggctggaggacgccgagcaggttctcggccagtctgagaacatcaaacgggacttc ttcaggaacctctcccactggatccagcagcacatggacatgaacgacgccgggaacttc ctcatcgagacgtgtgatgagacggtgtccagagacctgaagcagcagctgctgctgctg aacggcagatggagggagctcttcatcaaagtcaaacattacggccgagcagatgaggtg gacaaactccggcaggactaccaggacgccatgaacaccctgaagctgttcctggacgcc accgacgtgaagatgaccgctccggttcaggtgtccttcctgaacgtgcgggcgttcgtg caggacgtggaggaaatcaaacaaaaggtcccggcgatggaggcggcgtgcagggcggcg ggccgcacggcgcagctactgagcaaagacgctccgcaggaggagctcctccagatgaca gctgtgatggcctccatcaaggagcagctcagtaagatcagggaggggtgcctgcctctg ctcagagaggctcaggctctgctgccccccctggaggagatggagaagaacatcacgggc ttctaccaggctctggagaaggccagctgcatcaccggcgccggccgtccgggggggccc gctgacttcagacagcagtgtcaggagctggccaccttgactcacagctgcaagaagtgc ctgacggtgatcgagcggacccaccagaacatccagagaagcctgagcagcagtggagcc ctgcagcacctggacctggctctgctgcagaaacgcgtggcagagctgcagacggcctcg cagaacatgatcagggagtccacggagtggaggaggcaggaggagaccaacagcagcctc ctcaggaggtttgaggagtcccgagtggagctggagaaggtcctgaaggcggcccagagc tgcgtgacggaaagcggcgagccggaggatttgctgaggaaacacacggacttctttgag cagctggaccagcgggttctgaacacgttcctgaaggcgtgtgacgagctgacggacatc ctgcccgaacaggagcagcaggcgctgcaggagaccgtcaggaagctgcacaaacgctgg aaggacatgcagacggacgccccgctgcacctcctgcacgtgcaggtggaggcagagagg agccggctggagctgtccatgcaggagtgcaaggcggagctgaccagggagaaccgccac ctggtcggggtggggagtgagcggctccttaaggagcaccggagcttcttcggggagaag gggcccctgtcccagtgcgagaagaggctgcagctcatggaggagctctgccagaagctc cctgaggaggaccccgcccaccgcagcctgcagagcgccaggaaggagttaggcgagctc caggaggagatccagagcacacgactgaagctcctgcagcaccaggacaagtggaaggac tacaacaaaaggtacgctgagctctcctgctggctcatctccaaggagagccagctgagg ctcctgaggaaccgagccagtgaccacaggaagtacggtcaggtgaagaccgccatcgcg gagctgaggaatgaggcggagctgcaggaggggaacctgggctggctgaacgcccgcatg gcggatctgatcgaagtgtcggcagacgatgacgcccagcggcagggggcggcgctgacc aagctgtctgcagacctgaagggtctcgtagcgtctctgtcagaggctgagaagatgctg ctgaccgtgggggactgtgttcagttcagagaggaggtccaggccacgctggaggacctg gctcaggggcagaaggaggtgcaggccgaagcctcccagatcctggactcctctgatccc agagaggcccagcagctgctgctggtccaccagcaacacctgaagcgcctccgaatgaag aggaaggaggtccagcagctcttctccagaggtcagcagctgcaggtggaggaggcgctg gagggggctctgcagcaggacctgcagacgctggagaacagccttagcaggatggagcag agcacggactcgcaggagcaaagcctggaggtgactctggccgcctggcagcagcacagc gaccagcaggaggcggtgcagacctttgtcctcagagcacgctcctccatggacagggag ctgaacttcagcagcccagagagcctggaggtggagctggatcaggccagagtgctgctg aagcagagtgaaggcgaagctctgcacaccaagaccttgtcgaagagagccgccgaaatc cagctgagccccaaaaataagaccctgctgctgcagcaggcccactcgctcagggagcag gtggaggaggtggaggaaagcctgaagcaggacgtgaagctcctggaggacatgaagctg cagtgggacaccttcactgcaggctttgaaggtctgtcccagtggatctctgagacggag aagcagctggaggacgtcaggacgtctgctccacctgtggaggagcagagacggacggtg caggaggtccgtcgtgggcttcaggaacgagccgaagttctcccgcagctggaggcggac tccgcttcgctggcccgcttcgtgtcatcgggggaggcggctcgcatcaaggcccgcctg acccagattgggaggtactgggaggagcttaaggagagcgtccagcagctggacggactt ctccaggaacgctggcgtcaacagcagaagttcagcagcagcctggaggagcttcaggcg ggtctccaggagcttcaggccgagctgaatcggccaatgggaggctgcagctcctcctca gagaccttcagagctctgcagagccacacggatgtgtgtcaggctctgcagcagctgaag gcgcccctgctggcgctctcagcttctgcgcggcgcctcggcgacgacggaccagctgag cgaaccgtgacggagctgagcgccgctttggaacaggcgctgcaggaggcaaaggtcagg cagggccgcctggagagcctgctgtcttcatggcaaaggtttgagaaacagctgtcaaac ttcacttcctgtctggagagaatcgagtcttcatccagacctgagggtccatgtctgacg gctgataaaagcaaactgcgctttgagatccaggacttgcaggccctgcagccggagctg cggtccctgcagacggcccacgctgacctgcagactctggggatggacttttaccactct gcacccgagcagaaggtcctgcagatgaaggatgagctggaaaccctccatagaaggctg agggtccagcaggaagccctcccagaaagaatatcggaccttcagaaccatctgtgtcag ctggagcggttggacgggacccttctggagtttgcgcggtggagcgaaaggatgctgtca gatctacactccgcccctcagatccgcatcagcagcctgcaggccaccgtggaacacacc aaagagacccagaaggccctgctggagcagtccagtgtccgggagagcctggagcagcag gtccaagagctctgtcggctctgcgagcctgcagatgcgcagctgctgactagcagagca gacagctgcttgcagcctcagcgggaggcgctgcagacagcgcagctgcaggtggactgc ctgcagaagttggcagctttcctgcagacccacagcacggtggcgggggtactgcagggg ctcagacacaccgtggagagcgccgggagctgggactgtgcgcgggtggaggagctgcag ctggagctttccgccatcgtcgcagacatccatcagctggagacggcagccgtcagtctg gacagcagtctctgcaaagctcatctctacctgagctctgaggacggtaagtcctgccgc atgctggctgacgcgctcagcgcagacctggacggggtcaggaacctgctgggtaccaag cagaacgaggccgaggccctgggggctctgtggacctccttccgccagaggaaggatcag ctgctgagggcggtggaggacatcgaggaaaaagcagaaaagcagaccttgaaggaagcc agcctgcaggggctgcagctgcgactccgcctcttcaaccagctggaggacgagctccag gctcaccagcatgaggagcagtggctgcaggacaaggcggagcagctggcccgcagagac gcagagctggctggggaggtgctgcgtgagatgggcctgctgaggagcacgtgggaggcc gccaggaggctgatcgcagacaagcaggagcagtgcagcgtcctcaccgaactcatgaga gaataccagacgctgaaggcccgcgtctgccacgtcaccgggagggcggagccactggcc gacctgagctcgctcctgagggacgctgaggagaccaaacgggcgctggcaaagcacgag tccatgaaggcagagatgagcagcagacacgcagatctggaccagttcagctgcaaaggg aagcagctgctggtggaactgaagaagatccccgagtgtgacagccagcccataaagcag gacatggacgccatcgtggaccagtggctggatatgtctgaaaagatggatctgaacgtg gacctgctgatccgggtccttggcctgtgggaggacgtccggaacatcagcgaggacgtg gagagctggaccagcagctccaccgccgagcttaaccaaagcctgagcaacttcagcgac agccggaaggtgtcagcgcggctcgcagaactgcaggaagagatgagtgagaaggagcag aaactggaagctctgcagatcaaagtgtctgagctgaagaagagcagccagagtcaggag actcctgccaagctccaggtgttggagaatgaccttcaggagaagatcggtgcagtcaag aagcttcaccagcagtctgcagcaaacctgatggacttcagctcccagaggaggcagctg caggactacatcacccagatgtcagcgtggttgaggagcatggaggagtctctggggtcc tctccaactgggctggaccctgaggacatctgcagagtgaaggaccttcaaaaggagctc caaaaccagcaggggagcatcgacaccaccagggaggggctcaacaacctgtgcaggaag tatccttcagaggagctggcgggtctgggctcgtcactgacggacctcatcaagacctac gacagcgtgagccagatgtcagcccggacgctggcgtccctccagagcggcctccagcag cagttcctgcgcctggtccaggagttccacctgtggctgtcggaacagcgggacatagtg aaggaatgctcggaccgatcaggagacactcagacggtggaacggaagcttcagaaactg aagggggccatggatcgtgtggaggagggggaatcccgtcttactcaggtgtgtgaggaa ggagagaagctgctcctgcacctccctaaagccagcgctgcacaggtgcagcagcacctg tcctccatccagcaggactgggacggctttgtggagcagtgcaggcagaaccagcagatc ctggaggacagcgcctcactcatgagggggtttgaaggtcgcctggagaagctcaggcga tggctggaacagatggaaagcagagtaacgtccgaccagctggaggtcaagcagcacggc tcagaaaaagcccttctggagctggtggaggaataccaacaggaagtgctcagagaaagg gactccttcgagcgcctctgtcaggagggccaggcgctgaacgagggcgggcgcggcgat ggcggtgagacccgggtgtcggcccagctgcagtcgcagcaccaggccctgctgaggcgt atcagagagaggctgcgttgctgccagctgaccctgcaggagcagcaggccttccaggag acgctgcagagcagctggagctggctgagcggcgtgcaggagcggctggactccctcagc agcaccatcggcaccaaagagactctggagaagaggctgggcctggtgcaggacattctg ctcttgaagggggagggggaagtgaagctcaacatgaccgcagggaaaggagagcaggtc ctgaagcacagcagcttggagacccaggagaagatccacactcagctgcagagcctgaag gacgcgtgggccaacttgctgatgaccgccatcagctgccacagtcgcctggagtggacg gtgtcccagtggagcagcttccaggaagaccggagtcagctgctccagtggatggagtct gtggagaaggagctggggatggttctgctgcagcagccgggtctcaaagagaagtcggca ttgctggagcgagtgcgcagcatccaagctaacgtggatgcccacgccggaatcctgtca cgcctgacggagaaggcagccgagatgcacgaaaaaaccggggaccagacattcggacca gagtccagagtggagctcaacgcacgctttgctgatgtgtccgccgtcgtcaaggggaag gtgcggtccctgcagaacatcgtttctgagcacgagcagtacgtggacgccgtcagagac tttaatgactggctgatcacagcaaaggaggagctgcagcgctggtctgatctgtcagga gactcggtgagcatcagacggaagctctgtaaagttcaggaactgctggactctaagcag cgaggcagagagaggctaagccgcattcagaggtttggggccgtgaccagagacaacacc ggttcaggaggctacgaggctctggagcgagaggaagctgccctgctgtcgtcgtatgaa cagtgggagcggacagcgctgcagacgcgcaccagcctggagacggcgctgtcgcagatc tccaactcggagcaggagtttggcagcatgacggctcagctggagcaggacctgctggac ttcagcgatcagctgaaggactggaggctgcgactggtccaggtggagcgacatggcgac ggggaggagtctgcaacggcctggagagcagctaaggattgttgggaggagttagtgaaa gctgaagccacatgtgaccatctgaaggcccaactgaacgacctctgcaggttctccaga gaaatcagctcacagtctgaaagagtttcttctctgattaaagactacaacagtctgagc ctgcaggcctccagggagtgccagagcagggagaggcagctggaccacagcttccgctcc gtcttcagagacttccaacaatggctggtcaacgccaagatcaccacagccaagtgcttt gatgaaccccaaaatgtcagcgaggcgtcttcaagcctgcagaaaattcaggacttcctg agccagagagacacaggtgagtccaagctgaacaccgtgctcgtgagcgccgagcgactg ttcgccgtcgcagccaaagacacccgagacgcggtccgggctaaaagcaacgtggccaga gacgactggaagagcttcatgtccaacctccacagcagggaggcgggtctgcaggacctt ctgtctcagatgaaggactttgaggcgaacgccacgccttttcaggagaagctgaacgcc acagagctggtagtgcaggagagcagcagcagacttcatgatctcactgccaagagggag gagctgcaaaaactgcagtctgtgctggacgacttggcctctctggagattcagctttgc aggctgagggagaaggcccggctgctgatggaccagtatgcggccgggaagggctttgtg caccgcgtttcccagctctctgctcagctcctagctttgaccaccctgaccaaggagaag acctcccggatcgatcggatcgtagccgaacatcagcttttctctcagggcttgcaggag ctgcagagctgggtggcggacaccacccacatgctgcagaactactgcgcccccaccacc gacaaaagtgttctggacagccggatgatcaagctggaggctctgctgacggctcggcag gagaaggagatccagctgaagatgctgatcacaagaggagagtccgttcaaaggaacacc tccgcagagggggttcctgccctccaaacacagatgcaggagctgaaggactcctgggac gccctccactctgcgtctattctctgcaaaagccggctggagagcgccctgtcccagtgg accagttaccaggaggacctgcggcagttcacctcctgggtggagcgcatgcaggagaac ctggacgccgttggaaaaccctgtccggaaatgagggacaagtctgctcatctcagcaga gcaaagctgctgttggaggaggttctcaaccatcaaaccctgctggaaaccatcgccgcc aagagcgccggcatgggcgagaactatgcgactcagctggagctgcaagaacttgaggag cagtacggcgccgtcagagacagagcctcgagggcggtcagccgggcggaggagctgctg aaggcccatcaggagcatcagcgcgccctccacgcgttccaagactggctagtgcagcag caggaaacgctgggcagctacacccaactggaaggagacgtggacgcgctggaggagaca ctgcagaagctgcaggaaatgcttctgaacctgcggtggtcccccccccaggagctgcag ctgtgctgcaccgagggccaggctttgctcaacgccgtccagctcagccgggagctggtg ttgccttcaggcgcgcctcagacggaggacagagctctggagggccttcagcaggagtgg aggctgtaccaggcccggctggccgagacccgtgcccagctcaacggcactctggccagg ctgaggcagatggagcagaagttccagcgcctggacagctggctgaaaggcatggagagc aaagccgacgtgcgcagccaccgcaggtctgagcgcgccaccaaagaggctcagctgcag atgatcaagagctggcaggaggaggtgctggtctatcaggaggagatggagggcctctct ctgctggctcagcaggttctggacgagacgcacatcagcagccggatcagtaccagagcc acccagatcacagcgcgctaccacgctttggtcctgcatctactggagaccatcaggcag ctgcaggaggaggtgtcctgcatggaggaggctcagtctgcctcctccaccttctccgac tggctcggtgcagcgctgagcagcttcagctctgcggcttcaagtgttcaggtggaccgc tgtgccatggagaggaagatgaagaaactggaggccctgcaggcggacatggagcagggc cacgcctacctgaaggctctaagggagcgggcggagcgcgccattttgtttctggaggga cctgaagcagagcagctgacggaggaggtggacgctcatgtgctgcagctgcaggagctg caaggagctctgcgcgtggagcactgctccctggagaagtgcatgtgcctctccaaagac ttcacggagaagcacaaggcccaggcccagtgggtgaaggagaccagaaacctcctagca tccagtgtggagcccaaagccgagctctatcagaaaaaggctcagctggcgaagtacaag accatccagcaggtggtgctgtcccaggagtccacagtgaagtgtgtcctgaacaaggga gaggcgctgctggaggtcatcagcgacccctctgtgagcgacagcatggagaggctacag gcggactacctggagctctgcaccgccgctcagacacaggtggagagcctggcagagtgg gtcaaggagcacgaggactacaacacggagctgcaagaggctgagaagtggctcctgcag atgtccagccggctggtgacctccgactccatgcagaccagtagcatggagagcaccacg cagcagctggccagacacaaggctgtcatggaagagatctccagcttcgaggagcggctc tccaccttgaagcagaaaggagaaagtctcttcagcggctgttcggaccaagttcaggcc aagatgagccagcaggtccagacgcagctgcagggaaccagagacagctactctgctgtg tgcagcacggcccagcggatcttccagagtctggaccgggagctgcagaagcacgtcagc catcaggacgcgctgcagcagtgccaggcctggctgtgcggcgtgcaggaggagctgcag catcaggcgccgtccggtctgcaggaggcactcaagcaggtgaagcagtaccgggccctg caggagcaggccagcacctacctggacctggtctgctccctgtgtgacctgacggacgag gcggtgaggagagctgcagctcaggtccagcaggtcaaactcacgatagaggagcgcatg tccaccacccaggagctctcacaggcctggagggagctgaaggagcaaaaacaagatctg agcagctccttccaggacacggagcagcagcttctcagcctgtgtaggaggccggctgag ctggagatgaagattgctcaaaacgtgctcgctcaggccgaggagtgctgcctgcagctc cagaccaagcagaacgtcttcaccaaaatgacagagactgtggacagactgaccggaggc cagacctccccggaacacgccgatctggaccgtctgagccgctgctgggtggccctgcgt caccaggctgagaagctgcaagcgcagaaggaggaggatctgcagagggccgggggctac cacgcctgcatagcggctgtggaggcgctgttcgaggaggtgtctggagtttgggacaac ctggccagaacggatgcagaaagttcatcccagcacctggaggctctgagaaaactggca ggaactctggaggagcggaaagccgtcctggaggagctgaaggagcagaagcagaaggtc atccagcatctgaacctggatgacaaggagcttgtaaaggagcaggtcagccactttgag cagcgctgggctcagacgcagaacctgatcgacagaaaggtgcgggactccatggtgacc ctggaggatatgagtcaggtggaggcccggctgagggaggcgcgagattgggcggaggag cagcagcccgctctgtcagaggcaatgaagatgagtcctcctccggagttggctcagagc ttcctgttcgaccacctgagcatctgcagcgagctggaggccaagcagctcctgctggcc caggccgtggccgacgctgaccgggttctgccgcggctgggcctcagcgagcggcacaac ctgcagcagatgattgctgacacgcaggcagaggtggaggccctgagcgggaaggtggtg cagcgcaggaaacacctgagcaaggccttcacggagaggacgcagttcctgatggccgtg ggtcagtccatcgcctgggttcagcagaacgagaagaaggcccaggaagaggagtacatc gctctgctggctgaagacgtgtccaagcaggtccggtcctgcaggaacatccagagcagc ctgaaggcctaccgcagcgagctcacctccctgtggtctcagggccgagacctgatgagg gaggccagtgaggaggagaggagtgagctcctggccaagctgcaggagctgcagagcatc tttgaccggacgcttcaccggtgtggccagaagctgcaggagctggagaaggttctggtg tccaggaagtactttaaggcggatctggagaggatctgcctgtggctgaaacaagctgac attgtgactttccctgaaacaaacctgatggttggaggagctgagctggaggtccagctg cacaagtatgagcagatcatggagcaggccgtggagaacgaggaactgctcctcgctgtg cagagagcaggccaggaggtgctgcccaccctgaacgaggtggaccactgctacctggat gagaaactcaattccctcccgcagcagtacaacagcatcctggctctggccaaggagaag cgggagaagatccagcaggccatcctcaccaggaaggagtactcctccttcatagacgtc acccacaaagccctgaaggagctggaggagcagttcagcagtctggggacacagcctgtg ggcctggagacgaaggaggtgctgagcctccagagccagtacaaagccatcctggtggac ctcagcactctgggtctggctgtgagcgagctgaaccagaagaaagaaggtttccgcagc acggggcaaccgtggcgccccgacgagatgactcagctggtgagcctctacaacggcctg aagaggctggtggagcagaaggtggagcatctggacgagaccctggagtcctttgaggac cacaaggccatggccatgcagatggactctgagctgagagccaccaaggagcagctggac aaggtcaacacagagacgcagtccgccgaggagcggctgaagaactaccacaccctcgcc gggagtctgcagagcgccgactcccacctgtccaggctcatggagcagatgaacagcctg gccccacgcgtggaccgggccgcccacgacgcctccaaagagcaggtggtgctgtggcag gaggagctgcgctcgctgcaggccgccgtgggggagctgatcgaagagtgcgagacccgc ttcgtccacagcaaagacttccagacggagatggagaaaagcctggagtggctgcagcag atccgccgcgagctggactgcgccgtcatcgtggatgtgcgcgtggagaaggtccaggag gagatcaggaagcagcagatcatgcaggaggaggtgcagtccaggctccgcatcgtagcc gccctcagcagccgcgaaaagcagaagtacacgagcgccaatgagctggtccctgcccac gtgaaccgccggctggaggagatgaccaagctgcaggcagacgtccagagagcgctgacc gccaaacagatcactctggaggaagctctgctgctgtgtcagaagtaccacttcaggatg caggccgcctgtgagtggctggaggacgctgtgtccttcctgcagcaggccagcctgggg gtggatgtggagaaccacgaggagtgtctgcggcagcaggcagacatcgtggccacggag caggagttcctcattcacctggaggagctgcagagcctcctccccaagctggagactctg gtcaaccccacggcaaaggagcagctgcgactaagtgtggagtccgcccagcagagaggc gtagaggttcgagaccagctgcagtgccacaaggacgtcctgcacagctgcgtggctcag tggacgtccttccaggaggcgcggcagaccgtcatcgagctgatgaacgaggcagagaag aagctgactcagttttccacggccaaggcggctaccagtcaggaagcagaagaccgtctg agcagccacaggaccctggtgtcactagtgagcggctttcaggagaagctcagcagtctg gaggagcaggctactcagctggagctggtaggaagtgatgccagcaaggccaccatcagc cgctccatgaccacggtgtggcagcgctggacgcgactccgcagcgtggcgcgagggcag gagagagtcctggaagacactgcccaagagtggggcaccttcagggagaagatgctgaag gtgaggagcgtctcagaggatcttcagagccggttccccgacagcgctgtggagaaggcc tcgaaagctactctccagtctctgctggaccagcacgacctgctgagccaggacctggag cgggagctgtccgccctcatgctgctgcggcagtacgccctcagtctgctgcacgccgtg gaggtgccgtcgcccacaaatgaccacgaggagctgcccagcctgaaggagatcagggag gttcaggaccacatggaaagcctcctgactcagtccaggaccaagcgggctcacgtggct caagagctcagagaaagagaagaagtggagaaggaactgagtgttgtgaaggtctggatc cagcagagcagggagctgctcctcaaccccacgcaggacatcgaatccttgctgcaccag ctggaggtcctgcatgaggaggtcatcagcttccggcagaacgtggagaagttagcagag caacagcaaagcaaatacctggacctgtacaccatccttccctcagaaatctccatgcag ctggcggaggtctctctggctttagctgcaattgaagatcaggttctctccaaggaaagg gacattcagaagaccagagaaatcaaggaggacttcagctccagaatccaggacatgtca gaaaaactgaaaaccatctcaagcaaattcaacgagaaatctccagatgtggagcacgcc aaagaagaggtcaagagactgtttgaagacctggacggctgcggcagcgcgctctcagag ctggacgcctccctgcaggacttcagccgcagcaacccgctgctggccaaacagctgagt gaggctgtgagcaaactctcagagatgcaccaccacaccagccgcctggcagactgcagg aacaactggctcaagaaggccgtctgctacctggacgagtacaacgagatgctggacttc atcgtcaggtgggcggacaaagcccggagcctggtgagggcaaacatcatctggaactcc tctgtccacctgcaggagcagatccggatccaccaggcggtcctccgggagtcccgggag cttcatggagatctggagtcgatggcagagaaggtggagcttctgtccgaggtgctgcag gttcaggcgctgagtcagcaggtttgtgagctcagtcggcacaccgatgagcttcagcag agcatccggacgcagctgcaaagcctccaggacgccaacaagagcatggaaaccctggag cgagaggtcaaggctctccatgtggctctggagcagctccaggccgtgctgacctcccca gaagtgacccgccagagcctgaaagagcagctgctgcagagacagcggctgctggcagac atggagggcctgaaggtgcaggtgcaggcggtgcagcggtgtcagagcactctgcaggtt cctgaagacgtcatgcccagcctggccgtctgccacacagcgctgcggctgcagcacgaa gccagccagctgcagcacgtggccatacagcagtgcaacatcctacaggaggccgtggtt cagtacgaacagtacgaacaggaggttggggagctgcagggtctgatcgaggaggcgcac caggtcatccaggaccgccccgtccccagcagcaacatccaggagctgcaggcgcagatc ctccaccacgaggaactcgcccagaagatcaaaggctaccaggagcaaatcgcctccctg aactccaaatgcaagatgttggcggtgaaggccaaacacgccaccatgctgctgaccgtc agcgacgcccacgggcttcctgctgagctgcaggacgaggtgggcggggaggtcaggaaa tctgctgtcacaatgacggcgggccgctgtcacactctgctgtctccggttagcgaggaa tctggggaggagggcgccagcagtgaggtctgctcccctctagtgggtggatcctctcca gtgactccccctcaggacgcggactcaaaggaggggcagggaagactcacacgtgctgca gtcttggacatgtatgaccccacctcagagtctgtggcccacctggatgaactgcagcgc tcgtgggaatctctgaagaacgtgatcagcgagaagcagaggtctctgtacgaagctctg gagaagcatcagcagtatcagagctctcttcagtccatctcctcaaagatggagaccctg gaggacaaactcagcgagcctctggagcttcagaaaagtccagagagtcacatgaaggcc caccagggtctgctgacggagatccaggatgtccaggaggagatggagaggctgcagagc agtttcacccaagatgtgtctgctgctgtggactcagacgtgtctgagcagctggccatg cagtcctcgctgtcggtgctgggggagaggatgtccaccatccacatgaaggcttcgggg aagcaccagcagctggaggagcacctgagcgagcggcaggaggttcagcatcaggagcgt gtcctgcaaggctgctggctccaagcagaggagctgcaggagtggctgagtcaaatgcac cagggcgccgccctcatcctgctgccccacgccgccggggaggtggacgagcagctgtac aagtgtcagggcgtgctgctggaggtggaggagaaggtgtccgccctgtctgagctgtcc atgcggagcgacagcctgctgctggagagccccgcccacacccgggaggaggcccagcgc ctggcctccaggctgcaggcgctgaaggggggcctgctggagctgcagaggatgctacag gacaagcagacgagcatccagacctccctgcaggagccggaggacagcggctccgactcc agcctctcccagagctccagcgtgcaggactggctggcccaggcccggaccacgcggtcc cagcagcatgaagacagccttcagagacagagggagctggaggagcagctggccgagcag aagaaactccttcagtctgttgccagcagaggagaggagatcctcatccagcaggcctcc cccagcagcagctccgccagcctcccttcagactccgaggccgggctggagcagatgagg ccgaggtggaggagcctccagctggagctgaagaccaagctgcagctcctggagggaact ctggagcagaaccagaaccagaaccaggtacctggtgctgcagcagcatcaggaaccgcc ctccgctctcctcaggtgtttcctccagcgtctcgcgttcccgcgggggagttgttcagc ggtcccccagcggggaacgaaccctcgctgaagaccctctatgatgccttcagggacaca gtcagagatgctcagcctggcgattggggcggggcattggtagcgcagatggagcggcag ctcttctcagccgtggcgtccacctccttctggctggacggcgtggagagcagcgtcctg tcaggctctgagctgctggctgagaccacacgaactctgcagcagcaggagacgctgcag aaggacctgagctgcgtggcagaggaggtgaagctttgtgagtctctcctcgctggatct tcaggacttgcagaggaagaccggacgctgctgcaggacaacctggactgcttgcagggg aggttaagcgccttaggcggcgctttgggccaacgctgtgagcacatgaggagcagagct caggaactggcgctctaccagacggacctgcagcttcttcaaacggctctgatggagaag aaacgtcagctccttcaaggtgctgctggatccacagacagaccggcctgtgagcagctg gaggtcctgacctctgaggaggagaccctgaaggactttgagctccgaatcgcagagctg aagagcagaggaggtgatctgcaggccgaccaggcttcaaccagcaacctgctgaagctc caggactcctacgaggatctggtgctgattgtggcctccaggcgcagcgggctgaaccag aacctggcccagaaggagcagtatgagcgcgctctgcaagatctgaccgacctgctggac accgccaaggacaagatgtctgcggatgggagggtcctggcgggctctgtggaggacgtt cagaccctcctggacaaacataaggagttcttccagggtctggagacccacatggtcctg acagaagcctacttcaggaaggtcagcggcctgatgctccccaccgagggccaggctctg caggagacgctggcagaggctcagagagtcctgaaggaggcgcacaggaggggggtggag ctggagtggatggtgcaggtctggagccgcctggagcaggactatcagggtttgagccgg cagctggaggccctggagggccgcaccccctccgctggtctggaggaggagtcagaggag cgactgacggacaggatctccctgtatcagggcctggagggggggctggcagagcaccag cacaagctgcaccagctgctggatgagggcaaacatctgctgggggggctgtcctgcccc agtctggagagccggctcgcccagctgggcaaacgctggctcgaccacgcggccaaggtc aagaaggagcggcagcggctggaggcggtcctcaaacactggagcaggtaccagagagcg cgggcggacatcggcgagtggctgcagtcggctctggagcgcctggagttctggaacacg caggcggtgtcggtcccacaggagctggaaacggtccgagaccacctctctgcgttcctg gagttctccaaggagatggaggggaaatccagtctgaagaacgccgtggtttctgaggga aaccagctgctgcgcctgaagaaggtggacacgggggtcctccgctcagagctggctcgc atcgacgcgcagtgggcggagcttgtcacgcgcatccccgtggtccaggagaagctgcat cagatccagatggagaagctggcctctcagcacgccatctccgagctcttcaactggatc tccctgatggagactgtgatcgaggaggacgaggagaacctgaagagcgccgtggggtcc aacgtgattcaggactacctgcagagatacaagggcttccgggtggatgtgagctgtaag cagctgacggtggacttcgtgaaccagtcggtggcgcacgccggccttcaggaccctgag agcaggcacagcgagaagacggactttgccgagcgcctgggggccatgaaccgccgctgg cagatcctgcagggccgcctcagtgagcagatccagctcctggagaacctcctggagatg tggctggagtatgagagcagcattcaggccctgaaggtctggatgaacgctcaggaggag aggctgaggaggaagccccggctggaggacctgacgtcggtgcagaacgctctgaaggac tgccaggagctggaggagctgctgaaggacaaagagaaggacctggagaaggtggaggag cagggctgcgccctcgttcagaacaaaactgacgaggcctgtgccatcgtcatggagacg ctccaaggagtcaatcactcctgggccaacctgcaccacctgaccggacagctgaagatc agcctgacgtcggttctggaccagtggagtctctacaaacaagcctcggaggaaatcaac gcctacctgatgaaggggaggtactccgtgtcgcgtttgcgcctcctcacaggatccctg gaggccgtccagcagcaagttcagagtctggaggagctgcaggaggacctggagaagcag gagagcagtgtgaggaggttcggtgcgctgacccatcagcttctcagggactgccatcct tcggtgtcagactctctcaacaacagcctgaaggacatgaacgccagggataaaacggca gaacctgagcctgaagcaggaggtgctgtgtctgcgctcaggtggagcggtctgcaggag gagatcttggagcgtctgcagagcagcaaagcgctgcttcagctgtggcagcgctacaag gagctgcaccaccagagctgcagcggcgtccagctgcaggaggagaaagccgacgcgctc ctcaagagctcctgcagcaacgacatggcggacgaggagctccccagatggatccagggg tgcagcgagctgctgcggtcccaggctccccttcaggcctcgctggaggtcctgcagact ctgggggagcagctgaagcagcaggtggacacgtcagcgtcctccaccctgcagtccgac cacctgtgtctgcggcagcgtctgcgcgtggtggagcaggctctccgtggacagctcacc gccctgcagactggcgtccaggactatcagaccttcaaggatcagctggagactctgagc tgctggatcagggaagcagaggaggacttgaggctgcaggatcccaacggctgcaccagc ctgtccgtcacgcagagccgcatggaggggcttaaggagctcatgctgcagttcagcagc acggcgccagagctggagcggctgaacgagctcggctaccggctcccgctcagcgacgca gagatcaagagcctgcagaacctgaacagaacctggaccaccgcctccactcagaccacc gagaggttcagcaaacttcaggcgttcctgctgcagcagcaaaccttcctggagaaatgt gaagcctggatggacttcctgctccaaacggaggacaagctggctgtggaaatctccggg aactttctgagtctaatggagcagcaaaaagcccacgagcttttccaggctgagatgttc agccggcagcagatcctccactccatcatcagtgacggacagcagatgctggagcaggga caggtggaggacagggaggagtttggcgtgaagctggcgctgctcagcaaccagtggcag ggcgtggtgcggcgcgcccagcagaggcggggcatcatcgacagcctgatccgccagtgg cagcgctacaaggaactgctggagaaattaagcaggtggctgcaggacgtgtgccccccc gcagaggccgaggggggcagggttcccctgcagcaggcccgctgcaggctggaggccgtc cagctgaaggagaagctgctgcagcgccagcggggcagcttcatcctgacggtggaggcc ggccgccagctgctgctgtcagccgacggccaggcggaggcggagctgcaggcccagctc acccaggtgcaggagcgctggagggaggcctgctcccgcctggaggaccagaggaggcgg ctggccggcgtgctgaaggactggcagaagtgtgaggcggggatcgccacttcactggaa aaactccgctccttcaagaagcagctctcccagcccctccctgatctccacgaggagctg caggcggagcagacgcgctgccaggacctagagaaaacatctggaggctggactgcagac ctggaccacctgactctgctgaaggaggctctgacctggtccatcagtgcagaggacctc tcagtcttgcaggagcgcattgagctcctgcatcgacagtgggaggaaacccgcctccag ctgtcgctgcgccggcagcaggtcagcaagcggctgaacgagtggaccgtgtttgcagac aagtacaaggacatgtgtgagtggctcaccaacatggagagcaaggtgtcccagaacgga gacatcagcatcgaggagatgatcgacaggctccacaaggactaccaggaggagatctcg gtagcagagaagaacaagcagcagctccatgatctgggggagcgtctggccagggccagc cagcagaacaaagctgccgagatccagcagaaactcggcaaagtcggcgaccgctggcag cacctgctggacctgattggagcccgagtgaagaagctgagggagaccctggtggccgtg cagcagctggacaggaacatgagcagcctgcggtcctggctggcccacatcgaaagcgag ctctccaaacccatttcctacgactcctgtgacttcacggacatccagaggaagctggat ctgcagcaggagcttcagcgggacatcgagaaacacagcacgggggtggcgtcggtgctg aacctgtgcgaggtgctgctgcacgactgcgacgcctgtgccaacgatgcggagtgcgac tccatccagcaggcgactcgcaacctggaccgccgctggaggagcatctgtgccgcatcg ttggagaggaggctccggatcgaggagacctggcgtttgtggcaaaagtttctggatgac ttcactcgttttgaggagtggctggcgccttatgaggagactgctgctcagcccaactcc tcaggagttctgtacacagaagcgaaggaggagctcaagaagtttgaggggttccagaga ctggtccatgaaggacttccccagctggagctcatcaacaagcaataccgccgcctggcc agagagaaccgcaccgactcctcctgccgcctgcgagggatggccaacagcgccaaccag cggtgggacgacctgcagaggaggggggcagtcatcgtccgacggctgaagcacttcatc agccagagggaggactttgagacggcgcgtgacgccatcctggtctggctgacggagatg gacctgcagctcaccaacatcgagcacttctccgagtgcgacattcaagctaagacccgg cagctgcggtcctttcagcaggagatctctctgaccacagccaggatggaacacatcttc cagcagggcggggcgctgctcgagaagagcgagccgctggatgctgctgtgattgaggag gagctggaggagctccagcgttatcgtcaggaggtgtttggtcgtgtggagcgctactac aaaaagctgattcacctcccgcttgcagacgaggacgccgacgcctccttctcggaccgg gagctggacgagcccggagatctctccggcgtgccgtggaacgagcgttcgggggacggc ttcctgtcccccctggcctcatcggggcgttcagcctcgctggcggctcaactgcgggcc gagcactctggcagagacacgccggcgagcgtggactccatcccactggaatgggaccac gactacgacctgagccgcggcctggagagcgccggccgggcgctgcgggagcagcagagc gaggaggagttcctgcagccggcgccgccggggctgtcggatgttcaggttgcagagaac ctggaggcctttgttagactaactgagcaaaccctgcggtcctgcacgggagaacccccc cccctggaggcagtggaccccaccccaacagagcaggatccctcctacataggctacatg cgtctgctgggggagtgccgcggccgcatcgatgccgctaagaggatgggctcggagctg caggaggagggggaggtgctgtcggggctggtggaccccagcagctcagagtcgcaggct tcaggagtgatcgagcgctgggagctccttcaggctcaggacctcagcaaggggaggagc agccagcagcagcagcagctgacctctgacctctgcagcgtgtgcagctggctggaggag gccgaagcagacctgcagcagcagagggggcagggggtcacctcggacatgcagaccatc cagcatcacatcaggaagctgaaggagctgcagaaggcttacgacaagcggaagcccatc gttctctccattaacctgtgcagccccgacttcctgcagccggacctgcaggactcccag cagctgcaggtccggctgaaagacctgaacaagcattgggaccagctgggagtgtccctg gatgagtggaggtcctccctgcaggaggcgctgctgcagtgtcaggacttccatgagatg agtcacggcctcctgctgtggttggagaacatcgaccgccggaggaaccaggcgcttccc atcgacgccgacgaggacgccgacggtctgcagcagcgccacgatgccctgacgcaaatc cggcaggagctcctggactcgcagctgaaggtgtcctcgctgcaggacgtgtccctgcag ctgctgctgcactctcagggcagcggctgctcggaggccaaggagaaggtccatgtgatc gggaaccgcctcaaagtgcttctgaaagaggtgacccacgacctccgggagctggccaag accctggacatgtccagcagccagcaggatttgtcttcctggtcgtctgcagacgatttg gacacctcgagctccctcagccccgcctctggaaggagcacgccaagccgccaacgatcg cagcggggcgacagtagcgcgccacagcctggagcgtgtatgagcggcccccccctcagc aggtttcgcagcgccgctggatccggttcctccccttctgatgacggacagctgcccccc cgggcgtcgcggctgcggcgcgtcctgtgggtggcgctgcctctccagctgctcctgctg ctcctgctgctcctggccttcctgctgccgctgtcggaggactactgcgcccagtccaac acgctggcccactccatgtaccccatgctcagctacaccaacgggcccccgcctgtgtag

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