Oryzias latipes (Japanese medaka): 101175437 Help Entry 101175437         CDS       T02443                                  Symbol obscn Name (RefSeq) obscurin isoform X1   KO K17531   obscurin-RhoGEF [EC:2.7.11.1] Organism ola  Oryzias latipes (Japanese medaka) Pathway ola04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:ola00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     101175437 (obscn)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:ola01001]     101175437 (obscn)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:ola04131]     101175437 (obscn) Enzymes [BR:ola01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      101175437 (obscn) Protein kinases [BR:ola01001]  Serine/threonine kinases: CAMK group   Trio family [OT]    101175437 (obscn) Membrane trafficking [BR:ola04131]  Others   Rho GTPase associated proteins    Rho guanine nucleotide exchange factors (GEFs)     101175437 (obscn) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  I-set Ig_3 ig Ig_2 V-set Ig_4 Ig_5 Ig_6 Izumo-Ig V-set_CD47 C1-set SOS1_NGEF_PH fn3 C2-set_2 RhoGEF Ig_DSCAM-DSCAML_C Ig_CD22 PH Receptor_2B4 IQ RHG20_PH Motif Other DBs NCBI-GeneID:  101175437 NCBI-ProteinID:  XP_023820733 LinkDB All DBs Position 17:27814447..27885107 Genome browser AA seq 6340 aa AA seqDB search MDQNFFGGAPRFLTRPKAFSVCVGKDAALSCTIVGSPTPVVSWEKDKLKLTSGGRFKTVE DGDVYRLTIYDLTLEDSGQYMCRAKNSVGEAYAAVTLKVALPAEMSQRAPAFMVKPSSTR VGLGGDVVFHCRVAAHPEANFEWEKDGRYLGETNRIKIVSDGDSSTLKIQSVRSLDGGTY TCRAQNSAGRSQAAATLGVDTQDARHTSVDKNTSLLSHLQKRKEEMKKDISIYHSEEKSS SVSSSSTTNVADVLSSLNLEHQLRASALAKLPKGVFTRTCTVTEGKHAKLSCLVTGHPKP HIIWRKDGTNISEGRRHVIYEDQAENFILKILYCKQSDNGLYTCNATNMAGQTYSAVLVT VKEPKVPFRRKLQDVEVQEKTSAKLMCEVPLVATQANWFMEETRLEQSYKYHMEEDGTVR RLTIHNVTTNDDGVYICEMKEGSRTVAELTVLGNITKKLPRRTVVPVSDTVIFCVELEHP CPDVYWTRNGEKLKQDSRISIASTLRQYTLTIRDCQADDSGEVAFVAGDCKTSTRFSVTA ARKHPPDPPVDAVVQNKSDSSITFGWAPPDSDRPVPIKGYVVERRKVGASTWQRCNAGEL IVTTEISICNFTEEASYQFRISAVNDFGQSPYLEVPGSFFLEPTADLRKGLADSSAVSGQ EFSLSVELSAVCSGFWSLNGRLLRSGADYLITRSKTTHTLVIRNVTMEMNGAEVKFVGGG SESSCILSVKAPPVRFTNKSDLPAEVTCSVQDAAELTAEVSDFEAEVVWMKNGREVKVGK KYEYVVMDRKRTLVVHNVTEEDVGIYECVLGNEKLPIKLNLKDEPAKFLNKARGTMGLSS SLKGDLELSCEVSPASGVVVWRKDQVEITEDQRTIIFSKGTHRKLIIKGAKKSDEGHYSC ETAADKVTFHVKIKEAQAQAFFTNKESVQKEVRATLSQKVTLSCEVSDCKMEVKWHKDGK LLGSSRTVYPEAKGAVRQLVIEKAERSDAGEYTCEAGGEKLSFRILVSDVQPTFLNKDLV QKEVKATVSQKTTLSCEVADTKTEVKWFKDGKQLTSSKTVHTESKGKLRQLVIDSVEKKD AGEYICEAGPEKMAFKIQVAEMQPVFSNKDSVQKEMKANVSQKATLSCEVFDSNTEVKWY KDQKLITSSKTVHVEAKGKIRQLVIDGLDKKDAGEYTCESGTEKLVFKLQVADTQVQSAF LKKESVQKEVKATLSKTATLTCEVADAKTEVKWFKEGKLVTSSKTVHAESKGKMRQLVID SVEKRDAGEYSCEAGTEKMTFKIHLDEGQPKSGFSNKESVQKEVKATLSKTATLTCEVAD AKTEVKWFKEGKLVTSSKTVHAESKGKMRQLVIDSMEKKDAGEYSCEAGTEKMTFKIHLD EGQPKSGFSNKESVQKEVKATLSKTATLTCEVADAKTEVKWFKEGKLVTSSKTVHAESKG KMRQLVIDSVEKKDAGEYSCEAGTEKMTFKIHLDESASAFSNKDSVQKEVKAALSEKVTL KCEVADVKTEVKWYKDNKLLISSKTVHAESKGKSRMLVIDSMEKKDAGEYTCEAGSEKLD FKLKLSDVAVKFQKKSVKEKYIFEASENIVLATELTAQSGSVRWFRDEVELKEGGKYEMK RDGLSRTLTVKCSDAKDSGTYSCQTSDDKVEFKVQVQDAALKFVVPLKAASVESGGTLSL VCELNKALGDVVWKHDGKEIKPGGRHCIGVDGAKRALTLTGMTKEDEGDYSCDCKSDKTS AKVTTKAPRLVRLTTKLNNVVATEGKDAIFKCAVTPVDASVKWFHKNVPITVGPKYKTEH GAGTHSLTIASVTQKDAGEISVDAEGKTCKATLQVQHEPVTFQKKLENLTVEEQSEVKLE VELSKASDEVRWMKNSVVLQPAGNIEIRLDGAKQALVFKRITYDDRGLYSCETLDDKTQA KLTVERKKIRVIKGLADTKAHEAESAKFEVELSQEDVEGSWTRDGTKLKTGANCRIAVLG NKHTLTLSNLRREDAGTISFKAEGVHTSGKLVVTEPPALICKPLMDIKVSEREKVAFECE VSRANAEVRWLKDDLELKPGRNFGIHSSGQKRTLIITKCTPEDAGTYVCRTADDSTSAKL SVHVRDIKVVKKLEDVEVMEKESATFVCEVSHDDVEGHWYKGNAKLKASDNIKMRQEGKT YVLLFKCVSPEDMGEIKFTAEKASSVAKLKVKELPVKFVKKLRDKIAMYKHRVHLECHVS RASAGVKWFKNKTELKPSQKYEIKSEDVYRMLTINDVDSGDEETYTCDATDDRTSCKLLV EEQSISIVQELSSVEVTEPFAAVFEVEISMELVKPPAWTLNGVPIQEGPDVEMEKEGTMH RLTFKKTKASMTGLVQFTAGKSKSSAQLTVKERPLEIAEPISDVNAKEKSSATLTCKFSA TPKEVKWFKGQELLTASDKYSTKQKAATAQLTIQRLTEEDSGEYRCLSGPAESKGTLTVE AREIKITKHLADAEVDEDSDAVFTCEINYADEEAQWLLNDKVLFTNEVNTITHDGKVHKL TLKNLAPKDGGTITFQVRKVKESVALKVKEKRAVFLKSLDDVTGEEKGMITLTCEASKPR VSPVWKKEGKVLKAGPKYELLHTGKSLGLIIKDVTKDDAGEYSCDLGTEVSKSKVIVREI GIGITKWLKSTEVNEGETCSFECILSRESTDDFLWTVNGKTVANDGRVKIANQGRKYMLT IKDVTPDDSGEVVFSIKDLSSRARLTVEGKASSISKALQTVTTVQGEDAVFTCEVTQAGS SVKWAKDGKAIKVSQKYEISQQDTVRKLIIRSVSSKDCGEYSCEVVGGATTKAKLEIKEP IHKFVKALEDSQADEKSSVTLKCETAQTPSTVTWLKGHTELKAGSRYVMSQKEGVITLTI KDLEEKDTDIYTCDVGTAKSMAKVTVKALPATFTKNLINQTKAEGEVVLLCCELSKPAAT VQWKKGSELLKPGEKYDMKQKATSCEIQIKSLTIEDSGEYSCAVGDQKTFATLKVTALPP NFVQKLKSEEAEEGAGVALMCELSKAGVPVVWRKGTEVLKSGGKYQMRQKATVYELLINK VAPEDGGEYSCVCGTQKTTANLDIKVSPTTFKQTLKSQEAEEGASITLSCELSKPGLPVE WKKGTQVLRSGEKYQMKQNASVNELLINKVVPEDSGEYSCVCGDQKTTASLNIKAQRVTF KQTLKSQEAEEGASVTLSCELSKPGLPVEWKKGTQVLRSGEKYQMKQNASVNELLINKVV PEDSGEYSCVYGDQKTTASLNIKGQRVTFRRTLESTEAEEGAKVTLSCELSKPGLPVEWK KGTRVLKSGEKYLMMQKASLYELVIKEAMPEDSGEYSCMCGDQKTTASIKINACPPVFTK ELQSQTVEEGDSVTLQCELSKADVPLEWRKGQLGLCPCAKYEIKQTGRLAKLVIHDADPE DSGSYTCDTGDHQSTGDLTVKAKPVLFKTQLHNLESEAGQSASFRCETTKPGAIVVWKCA DRILATSSKYQLKQDGAVVELVIHKLQSADSGEYSCDTGYQRTSAVLTVKEVEVSILKFL ESCVVHEGEDVCFQCLLSHEDTPPVQWKLQDVPLQKNEMNLIKAEGRQHSLTLRGVTTAD SGTVTFTVGNHNSTASLTVKAAPVSFKKELENQVSAEGGEASLSCETTSSDCKVTWRRNS TILTHGKKYTMQQRDATHILIIHKLVKEDSGEYTCVTGDKKSTATLTVKEKVRIVRDLCD VTVSTGQDACFEVELSHIGVTNWEWWLGDNLLQNNDLNQMSSQGRVHRLVLKMVTTDESG DVAFVVGEEKSVACLLVEEKPKVLILEQPQSTVALEGESVTLACSISDPTGSVTWIRNNV AIRAGLKYDLKKNGAFHQLHIHNLGLDDSGTYTCDTGDARCDVTLTVEGAPTFFQKELKN QDAVEGDDITLHCELSKPGVHVEWRKGGVVLQPGKKYEMKQEKRVQKLFIRNLEPEDSGY YTCDAGNQLTTASLAVQVKEVFIVSGLKTTDVFVGEWAVFSCQLSGRAPGKVQWWLDGTL LENGPNAEIGEGEGHIHTLTLKNLATDDSGTVAFKAGSLTSAAKLLVKDPTVEVVSKMED LWVLENLPAEFICQYSRPVKAEWRKDGQPLHPDGQRVVVEQDWNVARLYIKHVSAEDRGT YSCEAEGTCVAASLYVEAKPITIVQGLENVEIFDGGEALFECGLSRPENKDCCWLLDGNP VKESPTAEIVTFESGRRHLLLLKEMRVKDSCTVTFKAGTASTSAKLTIKAWKVNIVKGLE DRVAAVGEKVEFSIQLEEAIPAAEVAWYANGVELKPGDLWTMRADGSVYHLVLRQVPLLP QQEITFAARDALSLAKLTIITVPDPPEDPEVLSKTSESVTLSWFTPLYDGGSPILGYRVE MRLVDSALWLPCHSEPVCNTEYVVGNLTSGSGYRFRVAAINRAGTGEPVELPLTVQLATK QEEVLVQPNLPPEAAEDADLHELWEASTKKRRMSREPTLDSISEQPEEDGKKGLAKKAET GLVSSQKVEIKSSVKEQTVVTRTAESKQANSVEEEIVSGGSTLVSYLKKSSKTAVAEVSE TETLSTEKFFAHFQVGEQKTVQQTDVKSVVTEHIDEKLISTEGASLMDITKEDEPELKHA AIKIQAAFKGYKARKDMRPVFREVFKDQTIEPNGTIHLDCVTEGKPDKVRWLKDGEPVMD GKHHHVDIYSDGTCSLVITAITTKDTGVYTCEVSNKFGTTSHSAKVTVGTARESSGRRPL SVGYSADSEPESSSGSEMDDSLRQARRRLRRLLRTCLPPDVEEEPFVSADEGDLHPPDPH SYREDDNYIYIRFDSRSEAEVASKRFQEMFTIHGVPIDTAIVAAGLHKVELRIKKMGYNQ DGTQTPTQDRQAPAFMAGATAAPVFLTELRSQDVADGYPVSFDCVVIGKPPPTVRWYKDG KLLEENDHYMINEDQEGCHQLIITSVLPTDMGVYRCTAENSSGIAATKAELKVDMSCSSD YDTAVDATETSSYVSAKGYASSRETETFESVAEDDQLPQVLDELHDVHVCPGSPIAKMQL RVKGFPKPRVYWFKDGQPVHASSRIQLSVERDVHSIEIMEVKREDMGEYSAYISNVAGSA YSSARLIVLSPGEIMPKDKKDSKEPLVPPRFLERFCNRKVKQGASITLSVKVEGSPTPMV SWLKEKSEEDVLWIKPETPRYKIASSGRQHSLILMDVESEHSAIYTCIATNRAGQCVCTA HLQVDDTPQPKKETMPSSSLGITVIPPGGETSRGTEGKIPYLGEVGTEEFLMKLTSQITE MVSAKFTQDSLQNQEVLQWMKSWPKNSTSLRVPGCDSDDETKTPSPSPHHGRSRPPSLIA DSSSESDEGDARGEMFDIYVATADYTPTLASKDSISLKEGQYVEVLDSAHPLKWLVRTKP TKTTPSRQGWVSPAYLDKKLKLSADSGDLPETSTEEVSEGEYKRKLFQLIQDLINGESEF VREVDFFTSHHQKHADSPDAGRDISSQKETIFRNIEDIKTFHSKTFFPKLSDCETDDDVA MCFLKNKEGFERYLQYLVGQSQAESAVSDKTVHRFFKDYTDKEQASADPAGPPVRSINSY LKQPLERIQKYKGILKDFIRNKARNGQNCCLLEEAYAMVSALPQRSDNTHHVSLIENYPA TLEVLGEPIRQGPFQVWEGAPGIRSSSRGHHRHVFLFKNYCIICKPKRDSNTDTQAYVFK NMMKLNNIDVNETVEGDDRAFEIWHEREDSVRKYTLQARTVTIKNSWLRDFRELQQRFSM PAWNPPDFVEILANCTAELGQTVKLACKATGVPKPVITWYKDGRQVEADPHHIIIEDPDG SCTLILDNMTADDSGQYMCFAASSAGNASTLGKITVQVPPRFVTKMRNCVFVAGEDAQFT CVIQSAPSPKIRWFKDGRLLTDQEKYQTYSELRSGVLVLVIKNLTERDLGHYECELSNRL GSAKCAADLVLPSAAARTGEKAIIIEVTEQETKIPKKTIIIEETITTVVKNPRMRRHRSP GLIVAGAHRSETSTPEPPSARPRRMPASRKTTIPTLYVTEPAGAEARPVESKPRWVEVEE VIEYKVNKSPRLSRRRGVSPAGSDRSATPSRAKRSVENPNANNSNNKLVQQDVSDHLLPQ EEEGSLVATGSPYGEPSELSSVLSEEDSEDQDDLTVIFESEEENNDCDSSRTQEPVTLKQ GDHILTLEDLEDYVPEEGETFGSSSSHRGADEKPCEVSVLQREIGGSTVGQPVLLNVGRP HAAPRQRSGFFCRFKEQLSSSLFTPPFPQGSETRRRPERRVPVQVSHAKLEVQPSYCSEV QRVEGGQQSFKTKVSTQTYGYTSVGNPVTLQIKDNLYQNQ NT seq 19023 nt NT seq  +upstreamnt  +downstreamnt atggatcagaacttcttcggaggggccccccggtttctcactcggccgaaggctttctct gtgtgtgtggggaaggatgctgcactcagctgcaccatcgtgggcagccccaccccagtc gtaagctgggaaaaagacaagctcaagctcacgtctgggggccgcttcaagaccgtggag gatggagatgtgtaccgcctgaccatctatgacctaacactggaagatagcggccagtac atgtgccgagccaaaaacagtgttggggaggcgtacgctgctgtgaccctgaaagtggcc ctgccagcagagatgtctcagagggcccctgccttcatggtgaagccgtcctccacacgt gtgggcttggggggagatgtcgtcttccactgccgggtggcagctcaccctgaggccaac tttgagtgggagaaggatgggcgctacctcggagagaccaaccgcatcaagatagtctct gacggcgacagcagcacattaaagattcagagtgttcgcagtctggacggcggcacctac acctgcagggcccaaaactctgcaggccgttcccaggctgcagcgacccttggcgttgac acgcaggatgctcgccacacgtctgtggacaaaaacacctccctgctctcccatctgcaa aagcgcaaagaggaaatgaagaaggacatttccatctatcactctgaagaaaagagcagc tctgtctcttcctcctccacaaccaacgttgccgacgtgttgagttcactgaacctggaa caccagttaagggcatctgctctggccaagcttcccaagggtgtgttcacccgcacgtgc acagtgactgaggggaaacatgccaaactcagctgcttagtgacaggtcaccccaaaccg cacatcatctggaggaaggatgggactaacatcagcgaaggccgcaggcacgtcatctac gaggaccaggccgagaacttcatcctgaagatcctgtattgcaagcagagcgataacggc ctttacacttgcaatgccacaaacatggctgggcagacctacagtgctgtgttggttaca gtgaaagagcctaaagttccatttaggaggaagctgcaggatgtggaggtgcaggaaaaa acctcggccaagctcatgtgtgaggtccctctggttgccactcaggccaactggttcatg gaggaaacgcgcctggagcaaagttacaagtatcacatggaggaggacggcaccgtgcgt cgcctcaccatacataatgtcaccaccaacgatgatggcgtttacatctgtgagatgaag gagggcagccggactgtcgctgagctcactgtcctaggtaacatcactaaaaagcttcct cgaagaacagtagttcctgtcagtgacacggtcatcttctgcgtggagctggaacatccg tgcccggatgtgtactggactcggaacggcgagaagttgaagcaagattcccgcatttcg attgcttccacgctcagacagtacaccctgaccatcagggattgtcaggcagacgactcc ggagaagtggcctttgtggctggagactgcaaaacctccacacgattctctgttacagct gcacggaaacatcctcctgacccccccgtcgatgccgtggtgcagaacaagtctgactcc tcgatcacctttgggtgggctcctcctgacagcgaccgtcctgtacccatcaaaggctat gtcgtggagagaaggaaagttggcgcctctacctggcaaaggtgcaacgctggagaactc attgttacaactgagatctcaatctgcaacttcactgaagaagctagctaccaattccgc atttctgctgttaatgactttgggcagagtccttacctggaggttcctggaagcttcttt cttgagcccactgcagacctgaggaaaggtctggcggacagctctgcagtttccgggcag gagttctctctgtccgtggaactgtccgctgtttgctcgggcttctggtctttaaatgga cgcctcctgcgtagtggagctgactacctcatcaccaggtcaaagaccacccacacactg gtcatccgcaacgtgacgatggaaatgaacggagctgaagttaaatttgtgggtggaggg tcagagagcagctgcattttatctgtaaaggcccctcctgttaggttcaccaacaagtca gatcttcctgcagaggtgacctgcagtgttcaagatgccgctgagcttactgctgaggtc tcagactttgaagcggaggttgtttggatgaaaaatggtcgggaggtaaaagttggcaag aagtatgaatatgtggtgatggatcgaaagaggaccctggtagttcacaacgtaacggag gaagatgtgggcatttatgagtgtgttttaggaaatgaaaagttacccataaaactcaac ctgaaagacgaacctgccaaatttctgaacaaagcaagaggaactatgggattgtcatcc tcactcaaaggagatcttgagttgagctgtgaagtctctcctgccagcggtgttgttgtt tggagaaaggatcaagtagaaattacggaggaccaaagaactataatcttttcaaaaggg actcacaggaagctcatcatcaagggcgccaagaaaagtgatgaaggccattactcctgt gagacggcagccgacaaagtcacattccatgtcaaaatcaaagaagctcaagcccaagct tttttcaccaacaaagagtccgtccagaaggaggtgagggcgactctttcccagaaagta acacttagctgtgaagtgtctgactgcaagatggaggtgaaatggcacaaagacggcaag ctgcttgggtcaagtcggacggtgtacccagaggcaaagggggctgtccgtcagctggtg attgaaaaagcagagaggagtgatgctggagagtacacatgtgaagccggaggggagaag ctttcctttaggatccttgtgtcagacgttcaaccaacgttcctcaacaaggacttggtt cagaaggaagtgaaagccaccgtttcccagaaaaccactttaagctgtgaggttgcggat accaaaacagaggtcaagtggtttaaagatggcaagcagctgacctccagcaaaactgtt cacactgaatcaaaaggaaaacttcgtcagctggtgatagacagcgtggagaagaaagat gctggagagtacatttgtgaggctggcccagagaagatggcttttaagatccaagtagca gagatgcagccggtcttctccaacaaagattcagtccagaaggagatgaaagccaatgtg tcccagaaggccactctcagctgtgaggtgtttgattccaacactgaagtgaaatggtac aaagaccaaaagctcatcacttccagtaaaactgttcatgtcgaggcaaaggggaagatt cgccagttggtaatcgacggcttggacaagaaggacgctggagagtacacctgtgaatct gggactgaaaagctggtctttaaacttcaggtggcagacacgcaggtgcagtcggctttc cttaaaaaagaatcagtccagaaggaggtgaaggccacgctctccaagactgccactctg acctgcgaggtggctgatgccaaaacggaggtgaaatggttcaaggagggcaaactggtg acatccagcaagacggttcatgcagagtctaaagggaagatgcggcagctggtcatcgac agcgtggagaagagagatgctggagaatacagctgtgaggctggaactgagaagatgact tttaaaatacacctggatgaaggtcaacccaaatctggcttctccaacaaggagtcagtc cagaaggaggtgaaggccacgctctccaagaccgccactctgacctgcgaggtggctgat gccaaaacggaggtgaaatggttcaaggagggcaaactggtgacatccagcaagacggtt catgcagagtctaaagggaagatgcggcagctggtcatcgacagcatggagaagaaagat gctggagaatacagctgtgaggctggaactgagaagatgacttttaaaatacacctggat gaaggtcaacccaaatctggcttctccaacaaggagtcagtccagaaggaggtgaaggcc acgctctccaagaccgccactctgacctgcgaggtggctgatgccaaaacggaggtgaaa tggttcaaggagggcaaactggtgacatccagcaagacggttcatgcagagtctaaaggg aagatgcggcagctggtcatcgacagcgtggagaagaaagatgctggagaatacagctgt gaggctggaactgagaagatgacttttaaaatacacctggatgaatctgcgtctgccttc tccaacaaagattctgttcagaaggaggtgaaggccgcgctctctgaaaaagtcaccctg aagtgcgaggtggccgatgtgaagacagaggtcaaatggtacaaggacaacaaactactg atttcaagcaagacggttcatgcagagtcaaagggaaaaagccgcatgctggttattgac agcatggagaagaaagacgctggagaatacacatgtgaagctgggagtgaaaagttggat ttcaaactaaagttatcagatgtggctgtcaagttccagaagaagtccgttaaggagaaa tatatttttgaagcaagtgaaaacattgttttggccactgagctgaccgcacagagcggc agcgtcaggtggttcagagatgaggtggagctcaaggagggcggcaagtatgaaatgaaa agagatggcctctcccggactctgacggtgaaatgttcagacgccaaagacagcgggacg tactcctgtcagacctcagatgacaaagtggagttcaaggttcaggttcaagatgcagct ttgaagtttgttgttcctttgaaagctgcttcagtggagtcaggcggcacacttagcctg gtttgtgaattaaacaaggccttgggcgatgttgtctggaaacatgacggcaaagagatc aaacccgggggcaggcactgcatcggagtagatggtgcaaagcgagctctcactctgacc ggcatgacgaaagaagatgaaggagactacagctgcgactgtaaaagtgacaagacttct gctaaagttaccaccaaagcgccacgactcgtgaggctgaccaccaagctgaacaatgtt gttgccacggagggaaaagacgccatttttaagtgcgccgtaacgccagtggatgccagt gttaagtggttccacaaaaatgttcccatcaccgttggtccaaagtacaagactgaacac ggcgcagggactcactcactcaccatcgcctctgtcacccagaaagatgccggcgagata agcgttgatgcagaaggcaaaacttgcaaagcaactctgcaagttcagcatgaacctgtg accttccagaaaaagctggaaaacctgacggtggaggagcagagtgaggtcaaactggag gtagagctcagtaaggcttccgatgaggtcaggtggatgaagaacagtgtggtgctgcag cctgcaggaaacattgagattcgtctcgatggagctaagcaggctctagtcttcaagaga atcacctatgatgaccgaggactctattcttgtgaaactctggatgataaaactcaggcc aagcttaccgtggaaaggaagaagatccgtgtcattaagggtctcgcagacaccaaagcg catgaagcagagagtgcaaagtttgaggtagagctcagtcaagaagatgttgagggctca tggaccagagatgggaccaagttgaagactggagcaaactgcaggatcgcagtccttgga aacaagcacaccctgacgctgtctaatcttaggagagaagatgctggaactatttccttt aaggcagaaggagtccatacttcaggcaaactggttgtcacggaacctcctgcgctgatc tgcaaacctttaatggatattaaagtttcagagagggaaaaggttgcttttgaatgtgag gtttctagagccaacgctgaggttagatggttgaaggatgatctagaactgaaacccggg agaaacttcggcattcattcctcaggacaaaaacgcactttgatcatcaccaaatgcacg cctgaagatgcaggcacctatgtctgccgcacagccgatgacagcacctcagctaagctc agcgttcacgtcagggatataaaggttgtgaagaagctggaagatgttgaagtaatggag aaggagagcgcgacttttgtttgtgaagtttcacacgacgatgtggagggccactggtac aaaggaaacgccaaacttaaagccagtgacaacatcaagatgagacaagagggcaaaacc tatgtgttgttgtttaagtgtgtttcccctgaagatatgggggagattaaatttacagca gaaaaggcatcttcagttgcaaaactcaaagttaaagaactgcctgtcaagtttgtgaag aagctcagagataagatagccatgtacaaacatcgggtccaccttgagtgccacgtgtcc cgcgccagcgcaggggtgaagtggttcaaaaacaagacggaacttaaacccagccaaaaa tacgagattaaaagcgaagacgtgtaccgaatgctcaccatcaacgacgtggactctggc gacgaagagacttacacctgtgacgccactgatgacaggacgtcctgtaaactactggta gaagaacagtccatcagcattgtgcaggagctgagctccgtggaggtgaccgagcccttt gcagctgtttttgaggtggaaatcagtatggagctggtcaaacctcctgcttggactttg aatggagttcccattcaggagggtcctgatgttgagatggagaaagaaggcaccatgcat cgcctcaccttcaaaaagacaaaagcctccatgacggggcttgtgcagttcaccgctggg aaaagtaaatcctcagctcagctcacagttaaagagcgtccgcttgagattgctgagcca atctctgatgtgaatgcaaaggagaaaagctccgccacactcacctgcaaattctcagcc acaccaaaagaggtcaaatggttcaaaggtcaggagcttctaacagcatcagacaagtac agcacgaagcaaaaagctgcgacagcgcaactcactatccaacggctgacagaggaggac agtggcgagtatcgctgcctgtctggacctgctgagtccaaaggcacactgactgttgaa gcacgggaaattaagatcacgaagcatctggccgacgctgaggtggatgaagacagcgat gccgtcttcacatgtgagatcaattatgcagatgaagaggcgcagtggcttctgaacgac aaggtgctcttcacgaacgaagtcaacaccatcacgcacgacggaaaggtccacaaactc acgctgaaaaacctggcgccaaaagatggaggaaccatcacatttcaagtgcggaaggtg aaagagtctgtcgcactcaaggttaaagaaaagcgtgcagtgttcctcaaatcactagat gatgttactggggaggaaaagggcatgataactctgacatgcgaggcatcaaagccaagg gtctccccagtttggaaaaaagaaggtaaagtcctgaaagctggacccaagtatgagctc ctgcacacgggcaagtctttagggctgatcataaaggatgtgaccaaagacgatgctgga gaatacagttgtgatctcggtacggaggtctctaagtcaaaggtcattgtgagagaaatt ggtatcggaatcacaaaatggctgaaatctacagaggtgaacgaaggagagacgtgcagc tttgagtgcattctgtctcgagagagcactgatgacttcctgtggacggtcaacggcaaa actgtggcgaacgacggccgcgtgaagatagccaatcaaggacgcaagtacatgctgacg attaaagatgtcacccctgatgattctggtgaggtggtcttcagcatcaaggacctgagc tccagagcaagattaacagttgaaggaaaagcatcctccatatcaaaagcacttcagact gttactaccgttcaaggtgaagacgcagtttttacctgtgaggtgacacaggctggttct tctgttaagtgggccaaagatggcaaggccataaaggtgagccagaagtatgagatcagt caacaggatacggtcaggaagctgatcatccgcagtgtatcctccaaagactgcggcgaa tacagttgtgaagtcgttggaggcgcaacaaccaaagccaagctggaaataaaagaaccg atccataaatttgttaaggccctggaggacagccaagcagatgagaaaagctctgtgact ttgaagtgtgagacagcacaaaccccatccacggtaacatggctcaaaggccacaccgag ctcaaggctggcagtcgatatgtgatgtcccagaaggaaggggtgataaccctcaccatc aaagacctggaggagaaggatacggacatctacacgtgtgatgtgggaaccgcgaagagc atggcaaaagtgacggttaaagcccttccagccacttttaccaagaatctgatcaatcag actaaagcggaaggagaggttgtgttattgtgctgtgaattatccaaaccggctgccact gttcagtggaaaaaaggctcagaacttctaaaaccaggagaaaagtatgacatgaagcaa aaagcaacttcctgtgaaattcaaatcaagagtttgacgattgaagatagtggagaatat tcttgtgcggttggggaccagaaaacatttgctaccttaaaagtcactgcgctgcctcca aacttcgtgcagaagctgaaaagcgaagaagctgaagaaggagccggtgttgctttaatg tgtgaactctcgaaagccggagttccagtggtgtggaggaaaggaacagaggtcctgaag tctggagggaaataccagatgaggcagaaggccactgtttatgaactccttatcaacaaa gtcgccccagaagacggtggagagtacagctgtgtgtgtggaacgcagaagacaacagca aacctagatatcaaggtctcgccaacgaccttcaaacagactttaaagagtcaagaagcg gaggagggagccagcattactctgagctgtgagctctccaaacccggacttcctgtggag tggaagaaaggaacccaggtcctgaggtctggagagaagtaccaaatgaagcagaatgct tctgtaaacgaactcctaatcaacaaggtggtgcctgaagacagcggagagtacagctgt gtgtgtggagaccagaagaccacagccagcctcaacattaaggcccaacgcgtgaccttc aaacagactttaaagagtcaagaagctgaggagggagccagcgttactctgagctgtgag ctctccaaacctggacttcctgtggagtggaagaaaggaacccaggtcctgaggtctgga gagaagtaccaaatgaagcagaatgcttctgtaaacgaactcctaatcaacaaggtggtg cctgaagacagtggagagtacagctgtgtgtatggggaccagaagaccacagccagcctc aacattaagggccagcgcgtgaccttcagacgaacactggagagcacagaagctgaggag ggagccaaggttactctgagctgcgagctctccaaacctggacttcctgtggagtggaag aagggaactcgggtcctgaagtccggagaaaagtacctgatgatgcagaaggcctctctt tatgaactagtgatcaaagaggcgatgcctgaggacagtggggagtacagctgtatgtgt ggagaccagaagaccacagccagcatcaagatcaacgcttgtccacctgtgttcactaaa gaactgcaaagccaaacagtggaggagggagacagtgttacattacaatgtgagctctct aaagctgatgttcctttggagtggagaaagggccaacttggtctttgtccttgtgccaaa tatgagattaaacaaacaggacgcctggctaaattagtaatccatgatgccgatccagag gattctggaagttacacatgtgacactggtgaccatcaaagcacgggcgacttaactgtg aaggccaagccagtacttttcaaaacccagctacacaaccttgaaagcgaggcaggacag agtgctagttttcgatgtgagaccacaaagccaggagccattgtggtctggaagtgtgct gacaggattttggcaaccagtagcaagtatcaactgaagcaggatggagctgtagtggaa cttgtcatccataaactgcagagtgctgactcaggggaatactcgtgtgatacaggctac cagaggacgtcagctgtcctcacagtgaaggaggtggaggttagcattctgaaattcttg gagagctgcgttgttcatgaaggagaagacgtctgcttccagtgtctgctttctcacgaa gacacgcctccagtccagtggaaactgcaggatgtccctctacaaaagaatgagatgaac ttgattaaagcggaggggcggcagcacagtcttacacttagaggtgtcactacagcagac tctggaaccgtcactttcacggtgggaaaccacaactccactgcctccctgacagtcaaa gcggcaccagtttcattcaagaaggagctggaaaatcaagtgtctgcagaaggtggtgag gcctcattgtcctgtgagacaaccagctctgattgcaaggtgacctggcggagaaactcc acaatactcacccacggaaagaagtacacaatgcagcaaagagacgctactcacatcctg atcatacacaagctggtaaaggaggatagtggtgaatatacatgtgtaacaggagacaag aaaagcactgcaactcttactgtaaaagagaaagtccgtatcgtccgagatctctgtgat gtgaccgtgtccaccggtcaggacgcttgctttgaggttgagctgtcacacataggcgtc accaactgggaatggtggcttggagacaacctcctacagaacaatgatctaaatcaaatg agcagccaaggcagagtgcaccgcctggttctgaagatggtaaccacagatgaatcaggg gatgttgccttcgtagttggagaagagaagagtgtggcttgccttttggtggaggaaaaa cccaaagtgttgatactcgaacagccgcagagcactgtggcattagaaggagaatcggtc accctggcctgctccatttctgaccccaccggttcagtcacctggatcaggaacaatgtg gccatccgagcaggtctcaagtatgacctgaagaagaacggggctttccaccagcttcat atccacaatctgggtctcgatgattcaggaacgtacacctgtgacactggagatgctcgc tgtgacgtcacgttgactgtggaaggtgctcctacgttcttccagaaagaactcaagaac caggatgccgtagagggtgatgatatcactttgcactgcgagctatctaaaccaggtgta catgttgagtggaggaaggggggtgttgtcctccagcctggtaagaagtatgaaatgaag caggaaaaacgtgttcaaaagctctttatacgaaacctggagccggaagacagtggctac tacacttgtgatgcaggaaaccagctcactacagcttctttagcagtgcaagtaaaagaa gtcttcattgtttctggtcttaagaccaccgatgtcttcgttggggaatgggcagtgttc tcctgccagctctctggtagggcacccggtaaggtgcagtggtggctggatggtacgctg ctggagaacggccccaatgctgaaataggggagggggagggccacatccacacactgacc ttaaagaacctggccacagatgattctggcactgtcgccttcaaagcgggcagcttaacc tcagcagccaagctcttagtcaaagatccaacagttgaagtggtgagcaagatggaggac ctttgggtgcttgaaaaccttccagctgagttcatctgtcagtactcacggccagtcaag gctgagtggaggaaagatggacagcctttgcatcctgatggccaaagggtggtagtggag caggactggaatgtggctcgcttgtacatcaagcatgtgtccgctgaggacaggggtaca tactcctgtgaagcagaggggacgtgcgtagctgcctcactttatgtggaagccaaaccc attactattgttcaaggcctggaaaatgtggaaatatttgatggaggtgaagccctcttt gagtgtggactgtctcgacctgaaaacaaagactgctgctggctgctggatggcaaccca gtgaaggaatcccctaccgctgagattgtgacatttgagagtggccgtcgccatcttctc ctcttgaaggaaatgcgtgtgaaagacagttgtacagtgacatttaaagccgggacagct tctacttctgccaaactcaccattaaagcctggaaagtgaacattgtgaagggtttggag gacagagtggctgcagttggagagaaagtggagttctccattcagttagaggaagccatt cccgcagcagaagtggcctggtatgcgaatggagtggagctcaaacccggcgacctctgg acaatgagagctgatggcagtgtttaccatcttgtcctgagacaagtacccctgttgccc cagcaggaaattacatttgctgctcgggatgctctctctttggccaaacttaccatcatt actgttcctgatcctccagaagacccagaggtcctcagtaaaacttcagagtctgtcacc ctctcttggttcactcctctttatgatggaggaagtccaattctaggctacagagtggaa atgcggctggtggacagtgcactttggctcccatgtcattccgagccggtgtgcaacacg gagtacgtagttgggaatctcacttcagggagtggatacaggtttagagtggcagcaatc aacagagcagggaccggagagcctgtggagctgccactgactgtgcagcttgctacaaaa caggaagaagtgctagtgcaacccaatctgcctcccgaagcagcagaagatgcagatctc catgagctttgggaagcatcaacaaagaaacggagaatgagtcgcgaaccaactctggac tcaatttctgaacagccagaggaagacggtaaaaaagggctagcaaaaaaagcagagaca gggctcgtatcatctcagaaagtggagataaaatcctccgtaaaggaacagactgttgtg actaggacggcagaatccaagcaggcaaatagcgttgaggaagagattgtttctggaggt tcaacacttgtgtcttacctcaaaaaaagtagcaagaccgctgtcgcagaggtcagcgaa acagagaccttaagcactgagaagttctttgctcatttccaagtgggagaacagaaaacc gtgcagcagactgatgtaaagtcagttgtaactgagcacatagacgagaaactgatatcc acagaaggtgcgagccttatggatatcacaaaagaagatgagcccgagcttaaacacgct gccattaagattcaagcagcttttaaaggttacaaggctcgtaaggacatgcgccctgtc ttcagagaagtcttcaaagatcagaccattgaaccaaacggcaccatccaccttgactgt gtgacagaaggcaaacctgacaaggttcgctggttaaaagacggagagccagtgatggac ggcaagcatcatcacgttgacatatacagtgatggtacttgttctctagtcataactgct atcaccaccaaggacacaggagtttacacttgtgaggtcagcaacaagtttggaacaact tctcatagcgcaaaggtaacagtggggacggcaagagaatcatcagggcgccgacctttg agcgtcggctacagtgcagacagtgagccagagagctcgtctggcagtgagatggatgac tccctcaggcaggcaagaagacgcctccggcgcctcttacggacatgtcttcccccggat gttgaggaagaaccgtttgtcagcgcagatgaaggagacctgcatcccccagacccccac tcttaccgcgaggatgacaattatatctacatccgctttgattcacggtctgaggctgaa gttgcttctaagagattccaggagatgttcaccatccatggagtcccaatcgatacagct atcgtagcagcagggcttcacaaagtggagctacgaatcaaaaagatggggtacaaccaa gacggcacacagacccccacacaggatcgacaggctcctgctttcatggctggagctaca gctgccccagtcttcctgacagagctgcgcagtcaggacgttgctgatggctatccagtc agctttgactgtgtggtgatcggaaagccccctcccactgttcgttggtacaaggatgga aaactgctggaggagaacgaccattacatgatcaacgaggaccaagagggctgccatcag cttatcatcacctctgtgttacccactgacatgggtgtctaccgctgcacggccgagaac agcagcggcattgcagccactaaagccgaactcaaggttgacatgtcttgcagctcagat tatgacactgcggttgatgctaccgagacttcctcctatgtcagtgccaaaggttatgcg tccagcagggaaacagagacttttgagtctgtagctgaagacgatcagctgcctcaggtc ctagatgagcttcatgatgttcacgtctgtccaggttcacctatagcaaagatgcaactt agagtgaaaggctttcccaaacccagagtgtactggtttaaagatggacaaccagttcac gcatcgagcaggattcagctctcagtagagagggacgtccacagtatcgaaatcatggag gtgaagagagaagacatgggcgagtactctgcttacatcagcaacgtagccggatctgcc tactcttctgcccgactgatcgtgctgagtccaggggagattatgccaaaagacaaaaaa gactctaaggagcccctggtgccgccccgctttctggagaggttctgcaacagaaaagta aaacaaggagcgagcatcactctgtctgtcaaagtagaagggtctcctacaccgatggtc tcctggttaaaggaaaagtcggaggaggatgtcttgtggatcaagcctgagacgcctaga tacaaaatagcaagttctgggcgccagcacagcctgatcctgatggacgtagagtctgag cacagcgccatctacacctgtattgctacaaacagagctggacagtgcgtctgcacggct catctgcaggtggatgacacaccacaaccaaagaaggaaacaatgccttcaagttctctt gggatcacagtgattcctccaggaggggagactagcagaggaacagagggtaaaatacct taccttggtgaagtaggcactgaggaattcctcatgaaactcacatctcagatcactgaa atggtttcagcgaaattcacacaagacagtttacagaatcaggaagtcctccagtggatg aaatcttggcccaaaaattccacatccttacgcgtgccaggttgtgacagtgatgacgag acaaaaaccccttcgccgtctcctcaccacggcagatccagacccccctccctcatcgca gactcctcctcagagtcggatgaaggagatgcccgaggagagatgtttgacatctatgta gcaacagcggactacacgccgactctggccagcaaagactccatctccctgaaggaggga cagtatgtggaagttctggattcggctcatccgctgaagtggttagttcgtaccaagccc acaaaaacaaccccatcccgccaaggctgggtctcacccgcttacctggacaaaaaactc aagctttctgctgactcgggtgaccttccggaaaccagcacagaggaggtctctgagggg gaatacaagagaaagctgttccaactgattcaagatttgataaacggagaatcagaattt gtcagggaggtggatttctttacgtcccaccaccagaagcacgccgactcccccgatgcc ggtcgtgacatttccagccagaaggaaaccattttcaggaacattgaagatatcaagacc ttccacagcaagacattctttccaaagttgagtgactgtgaaactgatgatgatgtagca atgtgtttcctgaagaacaaagaaggctttgagaggtatctccagtatctcgtaggtcag agccaggctgaatctgctgtcagcgacaagactgtgcaccgtttctttaaggactacaca gacaaagagcaggccagtgccgaccctgcaggtcccccagtgcgaagcatcaactcctat ctcaagcaaccccttgagaggattcagaagtacaagggcattctcaaggattttatccgg aacaaggcgagaaatggccagaactgctgcctgctggaggaagcgtacgctatggtgtct gcactccctcagcgctctgacaacacccaccacgtctccctgattgagaactatccggct accctggaagttctcggagaaccaataagacagggacctttccaggtgtgggagggggct cctggaatcagatcatcctccaggggccaccaccgccacgtcttcctctttaaaaactac tgcatcatctgcaaaccgaagagagatagtaacactgacacgcaagcgtatgttttcaag aacatgatgaagctgaacaacatcgatgtgaatgaaacagttgagggcgacgaccgcgct tttgagatctggcacgagcgggaagactctgtgaggaaatacactctacaggcccggact gttaccatcaagaactcgtggctgagagacttcagggaactgcagcagcgattcagcatg ccggcatggaatcctcctgattttgtagaaattttggcaaactgcactgcagagttgggc caaacggttaagcttgcctgcaaagctactggtgtgcccaaacctgtcatcacctggtac aaagacggccgtcaagttgaggcggaccctcatcacatcatcattgaagaccctgatggc tcctgcactctgattctggataacatgaccgccgatgactctggccagtacatgtgcttt gccgcgagctcagctggaaatgccagtactcttggaaagatcactgttcaagtacctcct cgttttgtgacgaagatgaggaattgtgtgtttgttgccggtgaagatgctcagtttact tgtgtcatacaaagtgcgcccagtcccaaaataaggtggttcaaggatggacggctgcta actgaccaggagaaatatcaaacctacagtgaactccgcagtggggttctggttctggtc attaaaaatctgacagaaagagacctggggcactacgagtgtgagttgtctaaccgtctg ggcagtgccaagtgtgcggctgatttagtcctcccctctgctgcagcccggactggtgag aaggctatcatcattgaagttaccgagcaggaaaccaaaatcccaaagaaaaccatcatc attgaggagactattaccaccgtggtgaagaacccacggatgaggagacaccgatcccct ggtttgattgttgctggtgcgcaccgctctgagacgtccacacccgagcccccatcagcc aggcccaggaggatgcccgcctctaggaagaccaccatcccaactctttatgtcactgag cctgcaggcgccgaggccaggcctgtggagagcaagccccggtgggttgaagtggaggag gttatagagtataaggtcaacaagtcccccaggctgtcgaggaggagaggcgtctcacct gcagggtctgatcgctccgccacgccctcaagggcgaagaggtctgtggaaaacccaaac gctaacaattccaacaacaagctggtgcagcaagatgtcagcgaccacctgctgcctcag gaggaagaggggtctctcgttgccacggggtctccttatggagagccaagtgagctgtcg tctgttctctctgaggaagacagtgaagatcaggatgatctaactgtcatctttgagtct gaggaggaaaataatgactgtgattcatccagaacacaggaacccgtcaccctgaaacaa ggagatcacattttgactctggaagacttggaggattacgtcccagaggaaggggagacg ttcggttcttcgagctcccaccgaggggctgatgaaaagccctgcgaggtctccgtgctc cagagggagattggggggtccacggtggggcagccggtgcttctcaatgtgggccggccc catgcagcgccgcggcagaggagcggcttcttctgccgcttcaaggagcagctctccagc agtcttttcacgcctcctttcccgcaaggcagcgaaacccgacgcaggccagagaggaga gtcccggtccaagtgagccacgcaaagctggaggtccaaccctcgtactgctcggaggtg cagagggtcgagggcggtcagcagagcttcaaaactaaagtgtccactcaaacttacggt tacacatccgtcggaaaccctgtcactcttcaaatcaaagataacctctatcaaaatcaa taa

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