Osmia lignaria (orchard mason bee): 117600488 Help Entry 117600488         CDS       T09775                                  Name (RefSeq) ryanodine receptor isoform X1   KO K04962   ryanodine receptor 2 Organism olg  Osmia lignaria (orchard mason bee) Brite KEGG Orthology (KO) [BR:olg00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:olg04040]     117600488    04990 Domain-containing proteins not elsewhere classified [BR:olg04990]     117600488 Ion channels [BR:olg04040]  Voltage-gated cation channels   Ryanodine receptor    117600488 Domain-containing proteins not elsewhere classified [BR:olg04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    117600488 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR SPRY Ins145_P3_rec MIR RR_TM4-6 RIH_assoc Ion_trans EF-hand_7 CFAP143 TrAA12 Serglycin DUF996 Motif Other DBs NCBI-GeneID:  117600488 NCBI-ProteinID:  XP_034171899 LinkDB All DBs Position Unknown AA seq 5159 aa AA seqDB search MADSEGGSEQDDVSFLRTEDMVCLSCTATGERVCLAAEGFGNRHCFLENIADKNIPPDLS QCVFVIEQALSVRALQELVTAAGSETQQENVGKGTGSGHRTLLYGNAILLRHQNSDMYLA CLSTSSSNDKLAFDVGLQQHSQGEACWWTVHPASKQRSEGEKVRVGDDLILVSVATERYL HTTKENDLSVVNASFHVTHWSVQPYGTGISRMKYVGYVFGGDVLRFFHGGDECLTIPSTW STAPSQNIVIYEGGSVMSQARSLWRLELARTKWAGGFINWLHPMRIRHLTTGRYLGVKEN NELYLVDRNEGTIETSTFWLRQEKDDQKIILEDKDLEVIGMPIIKYGDSTVIMQHATTCL WVSYKSYETKKKGVGKVEEKQAVLHEEGKMDDGLDFSRSQEEESRTARVIRKCSSLFTQF ITGLETLQVDRRASMFFQNVNLNEMVMCLEDLINYFAQPEDDMEHEEKQNRFRALRNRQD LFQEEGILNLILEAIDKINVITSQGFLVALSGDESGQAWDQISGYLYQLLAAIIKGNHTN CAQFANSNRLNWLFSRLGSQASSEGTGMLDVLHCVLIDSPEALNMMRDEHIKVIISLLEK HGRDPKVLDVLCSLCVGNGVAVRSSQNNICDFLLPGKNLLLQTQLVDHVASIRPNIFVGR VEGSALYQKWYFEVTVDHIEQTTHMMPHLRIGWANTSGYMPYPGGGEKWGGNGVGDDLYS FGFDGGFLWTGGRRTQVVQEANEPYIRKSDVIGCALDLTVPIITFTFNGAPIMGSFRNFN LDGMFFPAISCSSKLSCRFLLGGDHGRLKFQPPEEFSPLVESLLPHQILSLDPCFYFGNM NKVVLAGPWLVEDDTAFVPAPVDTSMINLPSYVEQIRDKLAENIHEMWAMNKIEAGWIFG EHRDDMRKIHPCIVQFERLPAAEKRYDTQLAVQTLKTILALGYYITMDKPPSRIKTLRLP NEPFLQSSGYKPAPLDLSAITLTPKMEELVDQLAENTHNLWAKERISQGWTYGLNEDSEM RRSPHLVPYPKVDEAIKKANRDTASETVRTLLVYGYMLEPPTGEQHEALLLEASRLRQLY FRTYRVEKHYAVSSGKWYFEFEVLTAGPMRVGWAKADCMPGSMLGSDESTWAFDGYNEEK VYSGTAETFGKQWQVGDVVGVFLDLIDRTISFSLNGELLMDALGGETSFADVQGDSFVPA FTLGVGQRAKLTFGQDVNTLKFFTTCGLQEGYEPFCVNMNRPVTYWYTKDQPIFENTDDM ADTRIDVARIPAGSDTPPCLKISHNTFETMEKANWEFLRLSLPVICQSTFVSESEKLRRW QEIKMRQNRLLSEQVEQSQQAAPSAHMEQIMRSGFSMSDIKGLQRNYSEDAVEADEMMKE SPLPMQRNKPARPPRKGSVYGSRQGNMENAISEVDMNGYGDMNGDVKDDKKKRGRSPFRK DTEDASFFSRKAKSPDAKAKTPEPPVRSDVSDKSTKTLPMNKASSRPPQVRISNMDLKVV PPQIPERNAPKAMSVLSGSGVESIGNEIYDAECLKLMNEYFYGVRIFPGQDPTHVYVGWV TSQYHLHTKDFNLSRVRKGSVVITDDYERPVEQVDRQSCYMVRADELYNEVTQDASGKGA SQGMFVGCFVDTATGWVSFTCEGKETSHKFRMEPDTKLFPAIFVEATSKEILQIELGRTS TTLPLSAAVLQNSERHVIPQFPPRLKVQCLKPHQWARVPNQSLQVHALKLSDIRGWSMLC EDAISMLALHIPEEDRCIDILELIEMDKLLSFHAHTLTLYAALCYQSNYRAAHALCQHVD QKQLLYAIRAEYMSGPLRQGFYDLLIALHLESHATTMEVCKNEYIIPLGQELKDLYEDEE MKHSLRYLETESVRPQMKMTDIREIPSSDQTIENIRSLYSPHFPLDVVRDYVMMALNEAV EVNQVHNRDPIGGSNENLFLPLLKLVDRLLLVGMLRNEDIMKLLIMIHPETWDPTFDKEG KDEHKKGLLHMKMAEGAKLQMCYLLHHLNDIQLRHRVESIIGFSHDFVGDLQSDQLRRYI EIKQSDLPSAVAAKKTREFRCPPREQMNAILSFKNMESADDPDNIPCGEDLINRMNEFHN NLMSYVSLHALQEAADAENEPIEEVQKPGAIKKLFNFINAVKELEEEPKPEPEPQRKTPE EVFRKVLIKTIVSWAEESQIETPKLVREMFSLLVRQYDTVGELIRALEKTYVINSKTRDD VALMWVGLSQIRALLPVQMSQEEEELVRERLWKLVNNHTFFQHPDLIRVLRIHENVMAIM MNTLGRRAQAQSDAQTQPQTTEGEPASKEKDTSHEMVVACCRFLCYFCRTSRQNQKAMFD HFDFLLENSNILLSRPSLRGSTPLDVAYSSLMENTELALALREHYLEKIAIYLSRCGLQS NSELVEKGYPDLGWDPVEGERYLDFLRFCVWVNGESVEENANLVIRLLIRRPECLGPALR GEGEGLLRAIIDANKMSERIADRRQVHDEAEGTTSVMQFEHPLPESDDDEDYIDTGAAIL NFYCTLVDLLGRCAPDSSVIEQEASTESVGKNESLRARAILRSLVPLDDLQGVLSLRFTL LNPAAGEEKPKSDMPSGLIPGHKQSVVLFLERVYGIETRELFFKILEEAFLPDLRAATML DRNDGYESDMALAMNRYIGNSILPLLIKHSKFYNEADNYASLLDATLHTVYRLSKNRMLT KGQREAVSDFLVALTRDVHELNVSQMQPSMLLKLLRKLTVDVSKLSEYTTVALRLLTLHY DRCAKYYGSTGGQGAYGASSDEEKRLTMVLFSNIFDSLSKMDYDPELFGKALPCLTAIGC ALPPDYSLSKNYDDEWYGSKSASTQSPDGPYNPQPINTSSVVLNNDLNQIVQKFSEHYHD AWASRKQENGWTYGEQWSEINKTHPRLKPYNMLNDYERERYKEPVRESLKALLAIGWSVE HAEVDVSSTNRSSMRRSSKSQVVATMFQSDSGNPFNYNPHPVDMTNLTLSREMQNMAERL ADNAHDIWAKKKKEELITCGGGIHPQLVPYDLLTDKEKRKDRERSQEFLKYLQYQGYKLH KPNRGGESEVATAGASVELRFAYSLLEKLIAYLDKATINMKLLKPSDTFSRRNSFKTSTR DIKFFSKVVLPLMEKYFSTHRNYFIAVATATNNVGAASLKEKEMVAALFCKLASLLRSRL AAFGPDVRITVRCLQVLVKGIDAKSLVKNCPEFIRTSMLTFFNNTADDLGHTILNLQEGK YSHLRGTHLKTSTSLSYINSVVLPVLTAMFDHLAACEYGSDLLLDEIQVASYKMLASLYT LGVDSSLTHDRKYLKTEIERNKPNLGSCLGAFSSCFPVAFLEPHLNKHNQFSLLNRIADH SLEAQDIMTKMESSMPTLETILTEVDQFVESDKTYNDLPHVVDVILPLLCSYLPFWWAQG PDNVNPTEGTYVSMVTSDHMNQLLKNVLKLIKKNIGNENAPWMTRIAAYTQQIIINSSEE LLKDPFLPLAERVRKRTDNMFHKEESLRGFIKSSTDDTSQVEAQIQEDWQLLVRDIYSFY PLLIKYVDLQRNHWLRNNIPEAEDLYNHVAAIFNIWSKSQYFLREEQNFISANEIDNMVL IMPTATRRPTTISDGTAPSGGGKKKKKHRDKKRDKDKEVQASLMVACLKRLLPVGLNLFA GREQELVQHCKDRFLKKMPEYEIAEFAKTQLTLPDKIDPADEMSWQHYLYSKLGQKKDSM EPVKAQQLEDVVARITDMAKVLYGLHMIDHPQQQSKGQYRSVVSIQRKRAVIACFRQTSL HSLPRHRAINIFARTYYELWLQDENVGQEVMIEDLTQSFEDAELKKMDKDEDESKPDPLT QLVTTFCRGAMTERSGALQEDPLYMSYARIISKSCGEEEEEGEDEGGGGEEEGGASIHKR GYKPLMRPMHKLMEQEMEKQKLLFHQARLANRGVAEMVLLHISACKGLPSEMVMKTLELG ISILRGGNIEIQRGMLNHLKEKKDVGFFTSIAGLMNSCSVLDLDAFERNTKAEGLGVGSE GAAGEKNMHDAEFTCALFRFIQLTCEGHNLDWQNYLRTQAGNTTTVNVVICTVDYLLRLQ ESIMDFYWHYSSKELIDPAGKANFFKAIGVASQVFNTLTEVIQGPCAQNQQALAHSRLWD AVGGFLFLFSHMQDKLSKHSSQVDLLKELLNLQKDMITMMLSMLEGNVVNGTIGKQMVDT LVESAGNVELILKYFDMFLKLKDLVSSPSFLEVDLNSDGWVYPKDFKEKMEQQKSYTDEE IEFLLACCETNHDGKIDYVAFMDRFHEPAKEIGFNLAVLLTNLSEHMPNEPRLARFLETA GSVLNYFEPFLGRIEILGGNKKIERVYFEIKESNIEQWEKPQIKESKRTYFYNTVVEAGE KEKLETFINFCEDAIFEMQHASALMAVEESGGIGKARESSYTYMSEDDEERNKDPIRRGI QTFKDGIYFFFSIFSPSNIKNKIAEMQQMTFLELFIGFFKMIFYSFYYSGFGVGCVISYF MRLLLALMKGPHVEEPVVEVKEEEEKPSRHLPALPPTPDESNLQVQAFGMDITKEEGGQI KIAPHESATSTPQSSIEETGESTPEEATGEDGTRVEGGGESETPVSLADLLGGEQARAQA AAAAEAAAAQQAAMAAVEAEAKQETITEPSGSSIDFSEYTHRIVSFLARNFYNLKYVALV LAFCINFMLLFYKVSSLAGDGDEEGSGDAIADILADISGEGPSGSGNGSGVEMGSGSGEN ESEEEEDVYALEYVEVAEDFYYMAHVMRLMAALHSIVSLAMLVAYYHLKVPLAIFKREKE IARRVEFDGLYIAETPEEDDIKAHWDKMVISAKTFPVNYWDKFVKKKVRQKYSETYDFDY ISNLLGMEKTSFSQQEEEGSGLIHFIVNIDWRYQVWKAGVTITDNAFLYSLWYFIFSILG NYNNFFFAAHLLDVAVGFKTLRTILQSVTHNGKQLVLTVMLLTIVVYIYTVIAFNFFRKF YIQEEDDEVDKKCHDMLTCFVFHLYKGVRAGGGIGDEIGEPDGDDYEVYRIMFDITFFFF VIVILLAIIQGLIIDAFGELRDQLENVKTNMESNCFICGLGKEYFDTVPHGFDTHVQQEH NLANYMFFLMHLINKPDTEYTGQETYVWNMYQQRCWDFFPVGDCFRKQNEAVEEEAKKK NT seq 15480 nt NT seq  +upstreamnt  +downstreamnt atggctgacagtgagggtggatccgagcaggatgacgtatcattccttcgcacggaggat atggtgtgtctatcctgcacagcaactggtgaaagagtttgcctcgcggccgagggtttt ggtaatcgacactgctttctcgaaaacatcgcagacaagaatattccaccggatctgtcg caatgcgtattcgtaatagaacaggctctctcggtgagagctttgcaggaattggttact gctgctggttccgagacgcagcaagaaaatgtaggaaagggcactggatccgggcacaga acgttgttatacggtaacgctattctgttgaggcatcagaacagcgatatgtatttggct tgtttatcgaccagctcttccaacgacaagttggctttcgacgtgggtctacaacagcat tctcaaggggaggcttgttggtggacggtgcatccggcatcgaaacagagatccgagggt gagaaggttcgagtcggtgatgatcttattttagtatctgtagctactgaaagatatttg cacaccacgaaagagaacgatttatcggtggtgaacgcctcgtttcacgtgacacattgg tcggttcaaccgtacggtactggaattagtcgaatgaaatatgtcggttacgtgttcggt ggtgatgtgctccgatttttccacggcggcgacgaatgcctcacaataccgtctacgtgg agtacggcgccaagtcaaaatatagtgatctacgagggtggcagtgtaatgagccaggca cgttcattatggaggctggaattagctagaacgaaatgggcaggtggattcatcaattgg ttgcatccgatgaggatcagacacttgaccacgggacgttaccttggggtgaaagaaaac aatgaactctacctggtcgataggaacgaggggacgatagagacgtcgacgttctggtta cgacaagaaaaagatgaccagaagatcattcttgaggacaaggatctcgaagttatcggt atgccgatcatcaaatacggtgactcgactgttattatgcaacatgccactacttgtctc tgggtctcgtacaagtcgtacgagacgaagaaaaagggcgtgggtaaagtagaagagaaa caagcggtcctgcacgaggaaggaaaaatggacgacggtttggacttctctcgttctcaa gaggaagaatctcgtacggctcgtgtgatccgaaagtgtagcagcttgttcacccagttc atcacaggcctagagacgctgcaagtagatagaagagcgtctatgttcttccaaaatgtg aatctgaacgaaatggtgatgtgtctggaagacttgattaattattttgctcagcctgaa gacgacatggaacacgaggaaaaacaaaacagatttcgtgctctgagaaatcgtcaggat ctgttccaagaggaaggcatactgaatctgatcctggaggccatcgacaagattaacgtc atcacgtcgcaaggttttctggtggcgctttcgggggacgagagcggtcaagcatgggac caaatatccggatacttgtatcaattattggcagctatcatcaaaggaaaccacaccaac tgcgcgcaattcgctaacagcaatcgactgaactggctgtttagtcgattgggttcgcaa gcttccagcgagggcaccggaatgttggatgtgcttcactgtgtacttatcgactcgcct gaagctttaaacatgatgagagacgaacacattaaagtcatcatctccttgcttgagaaa cacgggagggacccaaaagtcttggacgtcctctgctcactttgcgtgggtaatggcgtg gcagttcgttcgtcgcaaaacaacatctgcgacttcttgctacctgggaagaatcttctg cttcaaacacagctggtcgatcacgtcgccagtatcaggccgaatatattcgtcggtaga gtcgaaggttctgccctttatcagaaatggtacttcgaagttaccgtcgatcacatcgag caaacgacacacatgatgcctcacttgaggatcggttgggcgaacacctcggggtatatg ccataccctggtggtggtgagaaatggggaggaaacggcgttggcgacgacctctattcg ttcggtttcgacggtgggtttttgtggacaggtggcagaaggacccaagtggttcaggag gccaatgaaccgtacatcagaaagagcgacgtgatcggttgtgcgttggatttaacagta cccatcataacttttactttcaacggtgcacccatcatgggatccttcagaaacttcaac ctggatggcatgttcttccctgcgatcagctgttcttctaaattgtcctgcagattcctt ttaggtggtgatcacggtcgactcaagtttcaaccacctgaagaattctcacccttggta gaaagcctgctacctcatcagattttgtctctagacccctgcttctactttggcaacatg aacaaggtggtgttagcaggaccatggctggtcgaagatgacactgcttttgttcctgcg cccgttgacacatcgatgatcaatctaccatcttacgttgaacaaatcagggacaaatta gctgagaacattcatgagatgtgggcgatgaacaagatcgaggctggctggatcttcggt gaacacagagacgatatgaggaagattcatccgtgtatcgttcagttcgaacgactgcca gctgcagagaaacgttacgacacccagctggctgtgcagacgttgaaaactattttggca ctcggttattacatcaccatggacaaaccaccgtctagaatcaaaaccttgaggctgcct aacgaaccgttcctacagagcagcggatacaaaccggcgcctctcgatcttagcgccatc acactcacccccaagatggaggagctcgtggatcaattggcagagaacactcacaatttg tgggctaaggagaggatcagtcaaggttggacctatggactgaacgaggattccgagatg agacgaagtccacatttggtaccttatccaaaggttgatgaagctatcaagaaagctaat cgtgatacagcaagcgaaacagtgaggacacttttggtgtatgggtatatgttggagccc ccaactggagaacaacacgaagctttactactggaggcgagcagactacgacaattatac ttcaggacttatcgcgttgagaaacattacgcagtcagcagtggaaaatggtacttcgaa ttcgaggtactcactgctggtcccatgcgagttggatgggcgaaagcggattgtatgccc ggaagtatgctgggaagcgacgagagcacatgggcattcgatggttacaacgaggaaaaa gtatactcgggcacagccgagacatttggcaaacaatggcaggttggagacgttgtcggg gttttcctggatctaattgaccgaacgattagcttttctctgaatggagaattgttaatg gatgcactcggtggcgaaacatcgttcgcggacgtgcaaggggactcttttgtcccagct ttcacacttggagtcggacagagggcaaaattaacttttggtcaggatgtgaacaccctg aagttcttcacgacctgtggtttgcaagaaggatacgaaccattttgcgtgaatatgaat cgaccggttacctactggtacacgaaggatcaaccgatcttcgagaacacagacgacatg gctgacaccaggatagatgtagcccgaattccagctggttctgacactccgccgtgctta aaaatctcccataacacgtttgaaaccatggagaaagcgaactgggaatttctacggtta tccttgccagttatctgccaatcgaccttcgtgtccgaaagcgaaaagttacgaagatgg caggaaattaaaatgcgacagaacagattattgtctgaacaggtggaacaatcgcaacaa gccgcaccttctgcccacatggagcagatcatgagatctggtttcagtatgagcgacatc aaaggattacagaggaactactcggaggatgcggttgaggctgacgaaatgatgaaggaa tcaccgctcccaatgcaaaggaacaaacctgcgagaccacccagaaaaggatctgtttat ggatctcggcaaggaaacatggagaacgccatcagcgaagtcgatatgaatggatatggc gacatgaacggcgacgtgaaggatgacaagaagaaacgagggcgttcgccattccgcaaa gacacagaggatgcctcgttcttctcgcgtaaagcgaagtctcctgatgcgaaagcgaaa acgcccgaaccacctgtacgatccgacgtgtccgacaaaagcaccaagaccttaccgatg aacaaagcaagtagtcggcctccccaagttcgcatatcaaatatggatttgaaggtagtg ccaccacagatcccagaacgcaacgcaccaaaagcaatgtcggttctcagtggatccggg gtcgagtcgatcggaaacgaaatatacgacgcggaatgcttaaaactgatgaacgaatac ttctacggagtgaggatttttcctggacaggatccaactcacgtatacgttggttgggtc acttctcagtatcatttgcacacgaaggactttaatttgtcccgcgtgagaaagggctct gtcgttatcaccgacgattatgaacgtccagtagaacaggtcgatagacagagttgttac atggtgagagcagacgagctatacaacgaggtaacgcaggacgcatccggcaaaggtgcg tctcaaggaatgttcgtgggttgtttcgtggacacagcgacaggttgggtctccttcacc tgcgagggcaaggaaaccagccacaaattccggatggaacccgacacgaaattgttccct gctatcttcgttgaagctaccagcaaggagatccttcagatcgaactaggaagaacttcc acgaccttaccactgtctgctgcggtgttacaaaattcagaacgccatgtaataccacaa tttccacctagattgaaggtgcaatgtctgaagcctcatcagtgggctagagtacccaat cagtcgctccaggtacacgccttgaaattgtcagatatcagaggttggtcgatgttgtgc gaagatgcgatatcaatgctagctttgcacattcctgaagaggacaggtgtatagatatc ttggaactaatagaaatggacaaactgctgagcttccacgcccatactttgacactgtac gcggccctctgttatcagtcaaattatagagcagcccacgctctatgtcaacacgtcgat caaaaacaattactatacgcaattcgagcggaatacatgtccgggcccctacgacaagga ttctacgacttgctaatcgctttgcatctcgagtcacacgcgaccacgatggaagtgtgc aagaacgaatacattattcctttaggtcaagagctgaaggacttgtacgaagacgaagaa atgaagcacagcctcaggtacctggaaaccgagtccgttcgtcctcaaatgaaaatgacg gatatcagggaaattccttctagcgatcaaacgatcgagaacataaggagcctctacagc cctcatttccccttggacgtcgtgagggattacgtgatgatggccttgaacgaggccgtc gaagtgaatcaagttcacaaccgagatcctatcggtggcagcaacgagaatctattcctg ccacttttgaagctcgtcgataggttactcttggtgggtatgctgaggaacgaggatatc atgaagcttctaatcatgattcatcctgaaacgtgggacccgacgtttgacaaagaaggt aaagacgaacacaagaagggattgctacatatgaagatggcagagggagcgaagttacag atgtgctatcttcttcatcatctgaacgacatccagcttcgtcatcgcgtcgaatcgata atcggcttcagccacgactttgtcggcgatctgcagtccgatcaacttcgtcgttacatc gagatcaaacaatctgatctgccatcggctgtagcggcgaagaagaccagagaattcagg tgtccgcctcgcgagcagatgaacgcgattttaagcttcaaaaacatggaatccgcggac gatcctgacaacattccttgcggagaggatctgataaaccgaatgaacgagttccacaac aatctcatgtcttacgtgtctctgcacgctcttcaggaggcggccgatgctgagaacgag cctatagaagaagttcagaaacctggcgccataaagaagctgttcaacttcattaatgcg gttaaagaactcgaagaggaacccaaaccggagccggaaccacaaagaaaaactccagaa gaggtgttccgtaaggtgctgataaaaacaatcgtcagctgggctgaagaatcacaaatc gagacaccaaagttggtccgagagatgtttagcctcttagttcgtcaatatgataccgtt ggcgagttaattagagccctagaaaagacttatgtgattaacagcaagacaagggacgat gtcgccctgatgtgggtcggtttgagccagattcgtgctttactacccgtgcaaatgtct caagaagaggaggaactagtcagagaacgactctggaagctggtgaacaatcatacgttc ttccagcatccagatttaatcagagtcctaagaattcatgaaaatgtgatggcgatcatg atgaacaccttaggtagacgagcacaggcacaatctgatgctcaaactcagcctcaaaca acagaaggcgaaccagcttcgaaagaaaaggatacatctcacgagatggttgtagcctgc tgtagattcctgtgctacttctgtcgtacatccagacagaatcagaaggccatgttcgat cacttcgacttcctactggagaacagtaacatcttgttgtcaagaccatctttgaggggc tcgacgccattggacgtggcttattcgtctcttatggagaacacagaactagctttggct ctcagagaacactatctcgaaaagattgccatctatctgtctcgttgtggtttgcaatcg aattctgaactggtggagaaaggttatcctgatctgggatgggacccagtggaaggtgaa cgatacttggactttttaagattctgcgtgtgggtgaacggtgaaagtgtggaagaaaat gccaacctggtgatacgtttactgatcagaagaccggaatgtttgggacctgcacttcgg ggcgaaggtgaagggttgttgagggccattatagacgccaataaaatgtctgaacgcatt gctgaccgacgacaagtacacgacgaagccgagggcacaacgagcgtgatgcaattcgag catccccttccagaatcagacgacgacgaagactacatagacacaggagctgcgatcctg aacttctattgtactttggtcgatctcttaggccgttgcgctccggattcttctgtcatc gaacaagaggcttctacagaatccgttgggaagaacgagtctctacgagcgagggccatt ttacgatccctggtaccattggatgatctacagggtgttttatcgttgagattcactctg ttgaacccagcagctggtgaagagaaaccaaaaagcgatatgccatcgggtttaatcccg gggcacaagcaaagcgtcgtactgtttctggaacgcgtttatggcatcgaaacgagggag ctgttcttcaaaatactcgaggaagctttcttgcctgatcttagagctgccaccatgctc gacagaaacgatggctacgagtctgacatggcattggcgatgaaccgttacattggaaac agtattctacctctactgatcaagcattccaagttttataacgaggcagataattacgct agcctcctcgatgccacactgcacactgtctacagattgagcaagaacaggatgctgacg aaaggtcaacgtgaagccgtatcggacttcctcgtggcattgaccagagacgtccacgag ttaaatgtctcccaaatgcaaccaagcatgctgttgaaactgcttcgaaagttgaccgta gacgtgtccaaactgtctgaatacacgaccgtcgctctcagattgttgaccctgcactac gatcggtgcgctaaatattatgggtcaaccggtggacaaggagcatacggtgcatcgagc gacgaagagaaacgtctaaccatggtgctcttcagcaacatattcgactcgttgtccaag atggattacgatccagaattattcggaaaagccttaccttgtctcacagccatcggttgt gccctgccacctgattactcgttgtccaaaaactatgacgacgaatggtacggaagtaaa tcagcatccacgcagtcgcctgatggtccttacaatcctcagccaatcaacacctcgagt gtggttctcaataacgatctaaatcagatagtacaaaagttctcggaacattatcacgat gcttgggccagtcgtaaacaagagaatggttggacttatggggaacaatggtctgaaatc aataagactcatcccagattgaaaccttataatatgctgaacgattatgagagagaacgt tataaggaaccggttagagagagtttgaaagctttgttggctataggatggagcgtcgaa cacgcggaagtggatgtatcttctacgaatcgtagttccatgaggagatcatcgaaaagt caggttgttgccacaatgtttcagagtgattcgggaaatccgttcaactacaatcctcat ccggtggacatgaccaacctgacgctcagcagagaaatgcagaacatggccgaacgtttg gcggacaatgcacatgatatatgggcgaagaagaagaaagaagagctcataacttgtggt ggtggcattcatcctcaattggtaccatacgatttgctgactgacaaggagaaacgaaag 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tccttggaggcgcaggatatcatgacgaagatggagtcgagcatgcccaccctggagacg attctaacagaggtcgaccagtttgtggaatccgacaaaacctacaacgatcttcctcac gtagttgacgtgattcttcctctactttgctcctatttgcccttctggtgggctcaaggt ccagacaacgtaaatccaaccgagggaacttacgttagcatggtcactagcgatcacatg aaccagctattgaaaaatgttctcaaattgatcaagaagaacatcggcaacgagaatgct ccctggatgactcgtatcgctgcctacacccaacagatcatcatcaactcttcggaagag ttattgaaagatcctttcttgccacttgctgaacgagttagaaaacgtacggataatatg ttccacaaagaagagtcccttcgtggtttcattaaatcgtcgaccgatgacacgtcacaa gttgaagcacagattcaagaggactggcaacttttggttcgcgatatttactcgttctat cctctgttgatcaagtatgttgatctgcagaggaatcattggctcagaaacaacattcct gaagcggaggatctttacaaccacgtggccgcgatatttaatatctggtctaaatcacag tactttttgcgcgaggaacagaatttcatatcagcgaacgagattgataacatggtgctg atcatgcctacagcgactaggagacctaccaccatttcggatggaaccgcaccttctgga ggaggcaagaaaaagaagaaacatcgcgacaagaagagggacaaagacaaagaagtgcag gcatcgttgatggtagcctgtctgaagagactgttaccagttggtctgaatttgttcgct ggtcgtgaacaggaactggtacaacattgcaaggacagattcttgaagaagatgccggag tacgagattgctgaattcgccaagacccagttaacactgccagacaagatcgacccagct gacgaaatgtcctggcagcattatctgtattccaagttaggtcagaagaaagactcgatg gaaccagtgaaagcacaacagttagaggatgtcgttgcaaggatcaccgacatggctaaa gttctctacggtttacacatgatagatcatccgcaacagcagagcaagggtcaatatcga tccgtggtatcgatacaacgtaaacgagccgtgattgcttgtttccgtcaaacttcccta cattccctgcccaggcatcgggctataaacatctttgcacgaacgtactacgagctctgg ttgcaggacgagaatgttggtcaagaagtgatgattgaagaccttacgcaatcattcgaa gacgcggaattgaagaagatggacaaagacgaggacgagagtaaaccagatccgctcacg caactggtaacaacgttctgtcgcggtgccatgaccgaacggtccggtgctcttcaagaa gatccattgtacatgagttacgcccgaattatatcaaagtcttgcggagaggaagaagaa gaaggcgaggacgaaggtggaggtggcgaagaagaaggaggtgcctcgatccacaagcgg ggctataagccacttatgcgaccgatgcataaactgatggaacaagaaatggagaagcaa aagcttctgttccatcaagctcgtcttgcgaaccgaggggtggctgagatggtactgctt catatatcagcctgcaaaggtctacccagcgagatggtgatgaagaccttggaattaggg atttccattttgcgtggtggtaacatagagattcaacgaggaatgctgaaccacttgaag gagaagaaggacgtgggtttcttcacttccatcgctggtctaatgaactcttgcagcgtg ttggatttagatgcgtttgaaaggaacacgaaagcggaaggtcttggagttggttccgag ggtgctgctggagagaagaacatgcacgacgcagagttcacctgtgcattgttcagattc atccaacttacatgcgagggtcacaatctagactggcagaattatcttagaacccaagct ggtaacacaacaacagtgaacgtggtcatctgcaccgtcgattatctgttacgacttcaa gaatccatcatggatttctactggcactactccagcaaggaactcatcgacccagccgga aaagcgaatttcttcaaagccataggcgttgccagtcaagtctttaacacccttactgaa gttattcaaggtccttgcgcacagaatcaacaggcactcgcacattctcgattatgggac gcagtcggtggattcctcttcttgttttctcatatgcaagacaaattatcgaaacattcg agccaagtggacctcctgaaggaactgctgaatcttcagaaagacatgatcaccatgatg ctttccatgcttgaaggtaacgttgtgaatggaaccattggaaaacagatggtggacact ttggtggagtctgcgggcaacgtcgagctgatcctgaagtatttcgacatgttcttgaag ttgaaggacctcgtgtcgtcgcctagtttcttagaggtggatctgaacagcgatggttgg gtgtatccgaaggatttcaaagagaaaatggagcaacagaagagttacaccgacgaggag attgagtttctgttggcttgttgcgagacgaatcacgacgggaagatcgactacgttgcg ttcatggatcgtttccacgagccagcaaaagaaatcggcttcaatcttgctgttctactc accaatctgtctgaacacatgccgaatgaacccagactggctaggttcctcgagacagct ggctctgtactgaactacttcgaaccgttccttggcaggatcgagattctcggtggaaac aagaagatcgagagagtgtacttcgagatcaaagagtccaacatcgaacaatgggaaaag cctcaaatcaaagaatcgaagaggacctacttctacaacactgtggtggaagctggcgag aaagaaaaattggaaacgttcattaacttctgtgaagatgccatctttgagatgcaacac gctagtgcattgatggctgttgaagagagtggtggaatcggaaaagcgagagaatcctct tacacgtacatgtcagaagacgatgaagaaaggaacaaggatcccatcagaagaggcatt cagaccttcaaggacggtatatacttcttcttctctatattctctcccagcaacatcaag aacaagatcgcagagatgcaacagatgactttcttggaactcttcattggctttttcaaa atgatattctactctttctactattctggattcggtgttggttgtgtgatcagctacttc atgagattgttactggcgttgatgaagggaccacacgtggaagagcctgtcgtcgaggtg aaggaagaggaagagaaaccgtccagacatttacctgctttaccaccaacgccggatgaa tccaatctacaggtacaagccttcggaatggatataacgaaagaagaaggaggccagata aaaatagcacctcacgaatctgcaacttcgacaccccagtcgagtatagaggaaactggt gagagtacaccggaagaagcaactggcgaggacggtacaagggtcgaaggtggcggggaa tcggaaacaccagtttctttggccgatttattgggtggtgaacaagctagagctcaagca gcagccgcagcggaagcagcagcagctcaacaagcagccatggcagcagtcgaagctgaa 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ttgttgacgatcgtcgtgtacatctacacggtgatagccttcaacttcttcaggaagttt tacattcaagaagaggatgatgaagtggacaagaagtgtcatgacatgttaacgtgcttc gtgttccatctttacaaaggtgtcagagctggtggtggtatcggtgacgaaatcggtgaa cctgacggcgatgattacgaagtctatcgtatcatgttcgacatcacattcttcttcttc gtcatcgtcattctgctggctatcattcagggtttgattatcgacgcgttcggtgaactt cgagaccagctcgagaacgtgaaaacaaatatggagagcaattgtttcatctgtggttta ggaaaggaatacttcgacacagtccctcatggatttgatacgcacgttcagcaagagcat aatcttgctaattatatgttcttcctcatgcacttgatcaacaagccggacaccgaatac accggtcaagaaacgtacgtgtggaacatgtatcagcaaaggtgttgggacttcttcccg gtcggtgattgtttccgcaagcagaacgaagcggtagaggaagaggccaagaagaaataa

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