Onychostoma macrolepis: 131534284
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Entry
131534284 CDS
T09350
Symbol
lrrk2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
omc
Onychostoma macrolepis
Brite
KEGG Orthology (KO) [BR:
omc00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
omc01001
]
131534284 (lrrk2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
omc04131
]
131534284 (lrrk2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
omc04147
]
131534284 (lrrk2)
Enzymes [BR:
omc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
131534284 (lrrk2)
Protein kinases [BR:
omc01001
]
Serine/threonine kinases: TKL group
LRRK family
131534284 (lrrk2)
Membrane trafficking [BR:
omc04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
131534284 (lrrk2)
Exosome [BR:
omc04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
131534284 (lrrk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
LRR_4
LRR_8
COR
Roc
Ras
LRR_14
WD40_CDC20-Fz
Beta-prop_EML_2
WDR55
LRR_13
Ank_2
MMR_HSR1
LRR_9
Ank_3
Beta-prop_HPS5
LRR_LRWD1
LRR_EndoS
Motif
Other DBs
NCBI-GeneID:
131534284
NCBI-ProteinID:
XP_058623064
LinkDB
All DBs
Position
25:complement(22179258..22226098)
Genome browser
AA seq
2536 aa
AA seq
DB search
MADKEELGIRLKKLLVRLNLQEGKQLGTMVQIIQDLLFLSHTDHCVELFSDQNVHMPLML
VLSSHFNSKVQQVGWSLLCRLMEICPNTLDSLANPDEYEFTEVHKQILKVLSKYRNDCKM
MMVSLRALSLLLKSDEIVMQVLDEEEVDVFSLVLEAMRSFNDKEEVQLQGCAALQLLLQT
VSDAHLVEFIENKDHEVVLDALRRFMDSENVVLQALRVLIPLAASASNIEILMSKHVKCY
SLLCQAMDMWLDSEAIQETGCCLLQKFTSESYYNILVLNGVHKVAVKACVSYPANATVQT
TALSCLSALAECIVQNEGLDKEWNEEDEADQKVLVKKEATQGEEMLIWREACYTALERHA
DHAAVQEAACWALNSLLLHYHSFNHVELEGRPPLHSLIMAAMLLHSSSVEVFQAASCTLR
TLIQHHSRLRALLLSHGIHVNIVQLMRKHGSSSAVCESACKLLHTLFQGAKASLDDATLI
LGQILTALKTHNFIPEVQLEGLRASLVLLSPDRRLRKHGTSVPDPDTVDVSLQVLKNQCV
LEGAHTVYLEALNRFISSEEIQQCGLGVLSALADSSGAVDLMCQQGAIDTVLHTLQMFPQ
ERDVHYWGLSLLFHLISKKKLSRMMVPVLASVLVSSVRQHKEDAVMLLKGFQVVWKLLDT
CSSAAAWLQKEAFEKDIFQILRENMAEQCRDPLQAMSCLCLSKMVADSEIMYALLERACE
DGDVDMAECLILLGADINKKTKSDSLIYQVCDRGPPLVLLELLVSAGVHEQQLRGALSVC
VRKGDDPAVTLLLARLGVDHTNNALCLGSFHLGKMKATWLSALLSERKAQTPVNKKNSKG
QHLARQILSLQRNKEFVGVARLRSDASTSEYFTDEESDDSHISLDESLTRMFDDMESDGS
DGPLQGLLLLNDSPEVGRKPAWRQNSRRRHANSEGCHGETETSVPLHKRFNSHNTRGQGF
IESSTPAALPLAMDKEPIRLLDLSGNELGNLSCLMGVSALKQQTENLLRLDLSSNNLSEF
PSVLCQNLRSLTRLDLQGNQLQSLPVELLGLPALNTLNVSRNCIGPVLMLGPTVRSPALR
QLNLSFNQFTIFPFQLGQAMDRLEELSLEGNQISELSLPLHLAELKVLDISKNQVKIISD
HFLTECLKLETFIASVNKISSLSHLPSKITTVKLSQNNFTTVPEIIINLPNLRSVDMRNN
SIIDLPGPSFWVSVNLRELMFSHNRISALKLSGPVYKWARLEKLHLSSNKLTEIPPQIGM
LEDLTSLDVSQNEGLRSFPDEMGKLVHLWDLPLDGLQLQMDLKHIGNKTKDIIRFLQQRL
KKAVPYYRMKLIVVGSPCSGKSSLIHQLMRLKRSQWRSDQHTVGISVRDWAIKNKDKRNM
LLNVWEFSGGEECSGFHPHFMSSRALYLVLYDLSKGPSEIDTIKPWLFNIKAVAGQSPVI
VVGTHADVCEEHHLQECVLKLREELSQPGFPVIKENHILCACEESESISRLRKTICRELI
GFKIQGQPVMGQLIPDCYVELERRVLQERSHVPTDFPVLRHSRLLEIIQETQLQLEEGEL
PHAIHFLSEAGVLLHFDDPVLQLKDLYFIDPQWLCNLISQTLTLRSTGQGDSTRGVVQRT
TVEKFLNKSRCFPKDHLTQYFKLLEKFQIALPFGDDQLLIPSSLSDQRPVIELPHCENSE
VIVRLYEMPYFPMGYWSRQINRLLEVSAFLLYGKEKALRPNRIYWRKGIYLSWSADAYCL
VEALSLEENPASFIKITVPCSRKGRVLFGQVVDHIDSLLEEWFPGLLTTDVHGTGETLLK
RWALYSFSDGHNCQKMLLEDLLSNINADGLLVNPEDPSCTLPISQISPDLVLSDQPSRTI
LDPEQLEMELSMEYRLGDGGFGSVYKAVYKNEEVAVKIFNKHATTLYVHRLVRQELAVLG
RLSHPSLVGLLAASCNPHILVMELAPCGSLDSLFERENSSLSHKLQHRIALHVVDGLRYL
HSSMIIYRDLKPHNVLLFNLKTDAEIIAKITDYGIAQYCCSMGVCSSEGTPGFRAPEVAR
GNVIYNVQADVYSFGLLLYDLMTYGERISDGMKFPSEFDEVAVQGKLPDPVKYYGCSPWP
GFESLMRDCLRENPQDRPTSAQVFDRLNSVEMLCLMQELTLMSLPGECFTVSCASGGANG
GKNTRVWIGGGSCSQKLGCVTSLDLETGGSLNQEIDSSPILCMVIIRAPGSCSDWLVAGT
QSGSLFIMDTINAEVLHCLKSVKDSVTSLYFHIHRHFKNYLLVGTADGSLVIYEDSVLKV
KNGGPVKTLQVGDVNTPLMCLGPFSQTLERKELWAACGSKVFSLTVEYDICRSLDTKLKL
LYPQQSRISSDPCISQLVVDKHVYVSKMGGHTVEVWDKKTERMINLIDCAQLLGLCPTKK
PKAQNEEHSRQTVPSSVIVKALLVQHSSTLWIGTKAGHILLVEVSSCQLLQTISPHCHSI
RCMGSVLLDTLNRKNVILVLGRRQRMSQDQIKTQVPAEDSVLTVWNSSLPLEVRNLIRHC
ELRDKITSKMRETVHN
NT seq
7611 nt
NT seq
+upstream
nt +downstream
nt
atggctgataaagaggagctagggatcaggctgaagaagctgctggtgaggttgaatctt
caagaggggaagcagttgggcaccatggtccagatcatacaggacctcctgttcctgtcc
catacggatcactgtgttgagctgttttccgatcagaatgtccatatgcctctgatgctg
gtgctgtcatcgcatttcaacagcaaagttcagcaggtaggctggtctctgctgtgtcgt
ctgatggagatctgtcccaacactctggatagtctggccaacccagatgaatatgagttt
acagaggtgcacaagcagattcttaaggtgctttcaaaatatcgtaatgactgcaagatg
atgatggtgagcctgagagctctgtctctcctactgaagtcagatgagattgtgatgcag
gttctagatgaggaggaagtggacgtgttttccttggttctggaggccatgaggtcattt
aatgacaaagaagaggttcagctacagggatgtgctgctctacaactactgctgcaaaca
gtttctgatgctcatctggtggagttcattgagaacaaggaccatgaggtggttttggat
gcgctcaggcggttcatggacagtgagaatgtggtactgcaagctctgagggtcctcata
ccactggctgcttcagccagcaatattgagattctgatgtccaaacacgttaaatgctac
agtctgctgtgtcaggctatggacatgtggcttgactcggaggccatacaggagactgga
tgctgtttgttacagaaattcacatcggagagttattataacatactggtgctgaatggt
gtccataaggtggcggtgaaagcgtgtgtctcttatcctgcgaatgccacagtgcagacc
actgccctctcctgcctgagcgcgctcgcggagtgtattgtacagaatgaagggctggac
aaagagtggaacgaggaggacgaggcggatcagaaagttctggtaaagaaagaagccact
caaggagaggagatgcttatctggagagaggcctgttatacagctttagagagacatgct
gaccatgctgcagtgcaggaagctgcatgttgggctttaaacagcttgctgcttcattac
cactcattcaaccacgtggaactggaaggaaggcctcctcttcattctctcattatggct
gccatgcttttgcattcatccagtgtggaggttttccaagctgcttcctgtacactacgc
acactaatacagcaccacagtaggcttagggctctgctgctgtcacatggcattcatgtc
aacattgtgcaactgatgcggaaacacgggagctccagcgctgtgtgtgaaagtgcctgc
aaactgcttcacacactcttccagggagcgaaggccagtctagatgatgcgaccctgatt
ctcggtcagatcctgactgctctgaaaacacataacttcattcctgaagttcagctggag
ggtctcagagcgagtttagttcttctcagcccagacaggcgtttaagaaaacatggcacc
tcagtgccggatcctgacacagtggacgtgtccctgcaggtgctgaagaaccagtgtgtt
cttgagggagctcatactgtctatctagaggcacttaataggtttatcagtagtgaggag
attcaacagtgtggacttggtgtactctcggcactagccgacagttctggagcggttgac
ctcatgtgccagcagggggcgatagatacggttcttcatacgctgcagatgtttccacag
gagcgtgatgttcactactggggtcttagtcttctgtttcacctcatctctaagaagaag
ctctctcgtatgatggtgcctgtactggcatcagttttggtcagctcagtacggcaacac
aaggaggacgcagtcatgctactaaagggtttccaggttgtgtggaagttgttggacacc
tgctcgagtgccgcagcatggctgcagaaagaagccttcgagaaagacatcttccagatc
ctgcgggaaaatatggcagaacagtgcagagatccattgcaggcaatgagttgcctgtgc
ctgtctaagatggtggcggacagtgagatcatgtatgccctgttggagagagcatgtgag
gatggtgacgtggacatggcagaatgtctcatcctgctgggcgctgacatcaacaagaaa
acaaagagcgattcgctcatatatcaggtttgtgatcgggggcctcctctggttttgctg
gagctgctggtttctgcaggtgttcatgagcagcagttacgtggagctctgagcgtatgt
gtcaggaagggtgatgaccctgcagtcaccctcctcctcgcccgtctgggggtggaccac
accaacaacgccctgtgtctcgggagcttccacctcggaaaaatgaaggcgacgtggctc
agcgctcttctctctgagcgcaaagctcagactccagtcaacaagaaaaacagtaaaggt
cagcatttagccagacagatcttgtcactccaaagaaacaaagagtttgtgggagtagct
agattacggagtgatgccagcacatcagaatatttcacagatgaggaaagtgacgactca
cacatttcattagatgaaagcttgacccgtatgtttgatgacatggagagtgatgggagc
gatgggcctttacaaggattgttgcttttaaatgattccccagaagtgggcagaaaacct
gcttggagacaaaacagccggcgtagacatgccaattcagagggatgccatggtgagaca
gagacaagtgtccctttacataagcgttttaactctcacaacactagagggcagggtttt
attgaaagctccactcctgctgctcttcctttggccatggacaaagaacctatccgtctg
ctcgacctctcaggaaatgagctgggcaatctgtcctgtttgatgggtgtgagcgctctc
aaacagcagactgaaaaccttctacggcttgatttgagcagcaacaatctatcagagttt
cccagtgttctctgtcagaatttaagaagtcttacccgtctagatcttcaaggtaaccaa
ctgcagtcacttcctgtggaactcctgggtttgcctgcattaaacacactcaatgtttct
cgcaactgcattggtcctgttctgatgctgggcccaactgtgcgcagtccagccttacgc
cagctcaacctgtcctttaaccagttcaccatcttccccttccagctggggcaggctatg
gacagactggaggagctctcgttggagggcaatcagatatcagaactgtctctcccgctc
cacctggctgaactgaaagttttagatatcagtaagaatcaagttaaaatcatttcagat
catttcctcactgaatgtctcaagttggaaactttcatcgcttcagttaacaaaatcagt
tcattgtcacaccttccttcaaaaattaccactgttaaattatcacagaacaatttcaca
actgttcctgaaataatcatcaacttgccaaatttgcgttcggtggacatgagaaataac
agtattattgatctgccgggtccatctttctgggtcagtgtaaacctaagagagctgatg
ttcagtcataatcgcatctctgcactcaaactgagcggcccggtgtacaagtgggccaga
ctggagaaacttcatttaagctccaacaaactgactgagatccctcctcagatcggtatg
ttggaggacctgacgtctctagatgttagtcagaatgaaggtttgcgctctttccctgat
gagatgggaaagcttgttcatttatgggatctgcctctagacggtctgcagctccagatg
gacctcaaacacattgggaacaaaaccaaagacatcatcaggttcttgcagcagcgtctg
aagaaagctgtcccttattaccgcatgaaactcattgtggtcggcagcccatgtagcggg
aaaagctctttgattcatcagctaatgagactcaaacgctctcagtggcgatctgaccag
cacaccgtcggcattagcgtcagagactgggccatcaaaaacaaagacaagaggaacatg
ctgctgaatgtttgggagttctcaggtggtgaagagtgcagtggatttcaccctcacttt
atgagctccagggctctctatctagtcctgtatgatctgagtaaaggacccagtgagata
gacactatcaaaccctggctctttaacattaaagccgtagctggacagtctcctgtgatt
gtggttggaactcatgcagatgtgtgtgaagagcaccacctacaggagtgtgttctgaag
ctgcgagaggagctgtctcaaccgggctttccagtgatcaaagagaaccacatactctgt
gcctgtgaggagtctgagtctatcagcaggttgcgcaaaaccatctgtagggagctcatt
gggttcaagatccagggtcagccggtaatggggcagctgattccagactgttatgtggag
ttggagaggagagttttacaggagaggtcacatgtacccactgatttcccagtgctcaga
cacagcagactactggagatcatacaggaaacacaactgcagctagaggagggagagtta
ccccacgctatccacttcctcagcgaagctggtgtcctgcttcactttgatgatccagtg
cttcagctaaaggatttgtatttcattgacccacaatggctttgtaacctcatctcacag
acattgactctgaggagcactggtcagggggacagcactagaggagtggtacagcgaacc
actgtagaaaagtttctgaacaaaagccgctgtttccccaaggatcatctgactcagtac
ttcaaactattggaaaagtttcaaatagccctgcccttcggagatgaccagttacttata
ccaagcagcctatcagatcaaaggccggtgattgagctcccccactgtgagaattcagag
gtgattgttcggctttatgagatgccgtacttccccatgggctactggtccagacagatc
aaccgtctgttggaagtgtctgctttcctgctctacggcaaagagaaagcattgagacca
aaccggatctactggaggaagggcatctatctgagctggtctgctgatgcttactgtctg
gtggaggccttgtctctagaagagaaccctgctagcttcatcaagatcaccgtcccctgc
tctcgcaaaggtcgtgtgttgtttgggcaggtggtggatcatattgactctctgctggag
gaatggtttccaggcctcctcaccactgatgtccatggcactggagagacactgcttaag
agatgggctctgtacagcttcagtgatggacacaactgccagaagatgctgctggaagat
ctactctccaacatcaatgcagatggtttgctggtgaacccagaggaccccagctgtact
ctgcccatctctcagatctctccagacctggtactgagtgaccagccatccagaaccata
ctggatccagagcagctggagatggagctctctatggaatataggttgggagatggaggc
ttcggctctgtatataaagcagtgtacaagaatgaggaagtcgctgtgaagattttcaat
aaacatgcaactacactttatgttcatcggttggtacgacaggaacttgcagtacttggc
agactgtctcatcccagtctggtggggcttttggctgccagttgtaacccacacattctt
gtgatggaacttgccccatgtgggtctctggactcgctttttgagcgtgaaaatagcagt
ctcagccacaagctacagcacaggatagcactgcatgtggtggatggtctcagatatttg
cactcatctatgattatctatcgagatctgaagccgcacaacgttctgttgtttaacctg
aagacggatgctgagatcattgctaaaatcacagactatggcatagcacagtactgctgc
agtatgggtgtctgcagctcagaaggaacaccaggttttagagcaccggaggtcgcccga
ggtaatgtcatctataacgtccaggcagatgtatattcgtttggtctgctgctgtatgac
cttatgacctacggcgagcggatatctgatgggatgaagtttcccagtgagtttgatgag
gtggctgtgcagggaaaactaccagatccagttaagtattacggctgttctccgtggcca
gggtttgagtctttgatgagggactgtttgagagaaaacccacaggacaggcctacatct
gctcaggtgtttgatcgtctgaattctgtagagatgctttgtctaatgcaagagctgaca
ttaatgagtttgccgggtgagtgtttcactgtctcttgtgccagcggaggtgcaaacgga
ggtaaaaatactcgtgtgtggattggaggtggcagttgcagccagaaattgggctgtgtg
acatcactggatctggagacagggggaagcttgaaccaggagattgacagcagtcctatc
ctctgcatggtgatcatcagagctccagggtcatgcagtgactggttagttgctggtaca
cagtcaggttcactgttcatcatggatactataaacgcagaggttctgcactgtctgaag
agtgtgaaggactctgtgacatcactatactttcacattcacagacactttaagaattac
cttttggtcgggacagcagatggatcactagtcatatatgaagattcagtcttgaaggtg
aagaatggtggaccagtgaaaacactgcaggttggtgatgtgaacactcctcttatgtgt
cttggtccattcagtcaaactctggagcgcaaagagctgtgggctgcctgtggcagcaag
gtgttctcactcacagtggaatacgacatctgtagaagcttagacaccaaactcaaactg
ctgtacccgcagcagagtcgaatcagcagtgatccttgcatatcacagttagtggtggac
aaacatgtgtatgtaagtaaaatgggcggccacactgtggaggtctgggataagaagact
gagaggatgataaacctcattgactgcgcacagttactcggattatgtcccaccaaaaag
cccaaagcccagaatgaggagcattctagacaaacggtgccgtcttcggtgattgttaaa
gctctgttggtccagcacagcagtactctgtggattgggaccaaagcaggacacatcctg
ttggtggaagtctccagctgtcagctactgcagaccatcagccctcactgccactccata
cgctgcatgggctctgtgctgctagacacactcaaccgaaagaatgttattctagtactg
ggtagacggcaacgcatgtcacaagaccaaatcaaaacacaagtcccagctgaggattca
gtgctgaccgtgtggaacagttcacttcctctggaggtcagaaatctgatcagacactgt
gagctacgagacaagatcaccagcaaaatgagagaaacagtccacaactga
DBGET
integrated database retrieval system
