Onychostoma macrolepis: 131534314
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Entry
131534314 CDS
T09350
Symbol
hsd17b2
Name
(RefSeq) estradiol 17-beta-dehydrogenase 2 isoform X1
KO
K13368
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:
1.1.1.62
1.1.1.239
]
Organism
omc
Onychostoma macrolepis
Pathway
omc00140
Steroid hormone biosynthesis
omc01100
Metabolic pathways
Module
omc_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
omc00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
131534314 (hsd17b2)
Enzymes [BR:
omc01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.62 17beta-estradiol 17-dehydrogenase
131534314 (hsd17b2)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
131534314 (hsd17b2)
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Motif
Pfam:
adh_short
adh_short_C2
DUF1776
KR
Epimerase
Motif
Other DBs
NCBI-GeneID:
131534314
NCBI-ProteinID:
XP_058623127
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Position
25:22446798..22456875
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AA seq
377 aa
AA seq
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MEGIVEGCLGFLYDLLVVVCVGLLLLRVAEGRSVRWLVLLVVSGVTLTCLVHSSALKAGL
VSVLCSVIHYVGREGVMLPTQNKAVLITGCDSGFGHDLAKFLDSAGMRVFAGVLDEHSPG
ALELKKAASPNLTVLQLDITNSSQITQAHQYIQSQTGLWALVNNAGVLGYMCDGEILPIK
MYKKCLDVNFIGSVEITQVFLPLIRQSKGRLISISSMAGEVPLPGFAGYGASKAALISFS
GAIRQELSRWGVKVIIILPGAFKTNILGSREQWDSAQEDVLSGLSPEAMASYGEEYIRSM
QQRLAHMSSVSSSDTGPFLEALKHAILSPSPKPFYYPGASAWALPFLYRHCPTSLSDTIL
SQIFTSSDAQPAEVLNS
NT seq
1134 nt
NT seq
+upstream
nt +downstream
nt
atggaggggattgtagaaggctgtctggggtttctatacgatctgctggtggtagtgtgt
gttgggctgctgcttctgcgggttgctgagggccggtcggtgaggtggttggtgctgctc
gtggtttctggagtgactttgacctgtttggtccattcaagcgctcttaaagctggcctt
gtgagtgtgctgtgtagtgttatccactatgtagggcgagaaggggtcatgttgcctacc
caaaacaaggctgtactgatcacaggttgtgattcgggttttggtcatgatctggccaag
tttttagacagcgcagggatgagggtgtttgcaggggttctggatgaacacagtcctgga
gctctggagcttaagaaagctgcatctccaaaccttaccgtcctacagttagacattacc
aacagcagccagatcacacaggcacaccagtacatccagagccaaacagggctctgggca
ctagtgaacaatgctggagtgctgggctacatgtgcgatggagaaattctgccaattaaa
atgtataaaaaatgcttagatgtgaattttattggtagtgtggagattacacaagtcttt
ctgcctctgatacggcaatcaaaaggacggctcatcagtatatcaagtatggcaggagaa
gttccacttcctggattcgcaggatatggggcatctaaagcagcgctgatctcattcagt
ggagcgattagacaggaactctcacgctggggtgtcaaagtcatcatcattctacctgga
gctttcaaaacaaatattctgggcagcagagagcagtgggatagcgctcaggaggacgtc
ctcagcggtttgtctccggaagcgatggcgtcttatggagaagagtacatccgctcaatg
cagcagcggctggcccacatgtcctcagtatccagctcagacacaggaccgtttctggag
gctttaaagcacgccatactgtccccgagcccaaaacccttctattacccaggggcctca
gcgtgggctcttccattcctctacagacactgtcccacctcgctgtcagacacaatcctc
tcacaaatcttcacgagcagcgatgcccaacctgcagaagtcttgaattcctga
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