Oncorhynchus nerka (sockeye salmon): 115133948
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Entry
115133948 CDS
T07952
Symbol
lrrk2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2 isoform X1
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
one
Oncorhynchus nerka (sockeye salmon)
Brite
KEGG Orthology (KO) [BR:
one00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
one01001
]
115133948 (lrrk2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
one04131
]
115133948 (lrrk2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
one04147
]
115133948 (lrrk2)
Enzymes [BR:
one01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
115133948 (lrrk2)
Protein kinases [BR:
one01001
]
Serine/threonine kinases: TKL group
LRRK family
115133948 (lrrk2)
Membrane trafficking [BR:
one04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
115133948 (lrrk2)
Exosome [BR:
one04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
115133948 (lrrk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
LRR_8
LRR_4
Roc
COR
Ras
LRR_14
Arf
LRR_9
LRR_6
Beta-prop_EML_2
LRR_NXF1-5
Ank_3
LRR_R13L1-DRL21
Beta-prop_RSE1_2nd
LRR_13
Kdo
TFCD_C
Gtr1_RagA
LRR_LRWD1
Motif
Other DBs
NCBI-GeneID:
115133948
NCBI-ProteinID:
XP_029523263
LinkDB
All DBs
Position
LG9a:2407662..2464255
Genome browser
AA seq
2558 aa
AA seq
DB search
MVNKEELEERLKKLLVRLKNLQEGKQLSTLVQIIQDLLFLAHTDDCAAELFEDKDVHVPL
MVVLSTYSNSRGVQQVGWSLLCRLMEICPSTLDSLVRPLGAGKDWEVLGVHQQILKVLSQ
HSGDCRVMMVGLRALALLLRSDVIVLLIRDEEEDVFSLIVEGMKTFPSSEEVQIQGCRGL
QLLLDRVSDDDLVEFLENQDHSVVLGALHHFHDSEDLFLQAMKVLLPLAGPASNVEILMS
GGERCYSVVAGAMESFPAVEALQEVGCCLFRKFTSERYCSILVLNGVHRVTVRACLTYPE
NATLQAAALSCLAALTETIVQSKAVVNEGMEEENRGKEEVVDDVGLCWMEACCRALEVHA
ADSTVQEAACWAIHSLLLHGSESWHHSTEEQDGRTPVHRQIMAAMLLHSSSPGVFQAAAS
AMGTLITYNSKMRSLLLSNGLHVNVVEMMKRHLSSPEVSAGGCKLLHLLFKGRMASLDEL
DMAMGQILRAMKVHNFIPEVQLEALRASLAFLCPDRSLRVSDHGVSVADPDTVDVSLRVQ
KNQSVVEGAHTVYLETLNRFISSAAIQECGLRVLSALADCSGAVDLLCQQGAIDTVLHTL
QMFPREREIHYWGLNLLCCLVSKKKLSRMIVPVLASVLVTSLLQYREDTEMLLKGFQVAL
RMLDACSGAAGELQREGFDREIFLQLKEGPPDRYSYPLSQLRKAACLALSKMCGDAELRY
SMLEKACKDGDVLMAECLIQLGADINKKTKTESLIYQVCEQGGPLQLVVLLLSRGVHEQH
LRGALGASVRRGDGPAIIQLLGRLGLDLNNNALCLGGFRLGRVDAAWLSPLLAERGRANS
LPSSTSKGACLARYVLSFQRGKTTPTPSTPRSLADPCLTSGYMSDESDDSSFLSLEDSLV
FNDDMESDGSDSLLLALSTNDLSEEWKAGSQKRKNGRRRHFSSESCIHPKGVQGEVELNE
PLQRRYGRTTPNQKGIHSPVLSSGYNSSPLVGDREWIRLLDLSGNELDSVSCLLGDGSVR
QQLEHLYRLDLSQNSLSEFPSGLCESLKSLTRLDLQGNQLQSLPAELLALPSLTMLNVSR
NCVGPLLTLDPAVTCPSLRQLNLSYNHITTFPHQLGRAMERLEELSLEGNRMSELWSPLC
LLEMKLLDISKNSVESISRDFLSGCPKLENFSACTNHLSSLSHLPSKITTLKLSHNSFTT
IPQAVLDLPNLRSVDMRTNDITVLPGPCTWASVNLRELMFSQNRIGVLDLSGPEVYKWAR
LEKLHLSDNKLTEVPPQIGLLEELTSLDLSRNGGLRSFPDEMGKLSRLWDLPLDGLRLSL
DLKHIGNKTKDIVRFLQQRLKKAVPYYRMKLIVVGNADSGKTALIRQLMKLKRSQWQMER
PTAGIDVRDWTIRDRDKKNMVLNVWDFSGGEEFSGSHPHFLTPRALYLVVYDLSKGAAQV
DALKPWLFNIKAVAPLSPVILVGTHTDVSEDLQLQACLDKIRQELLNHQGFPAIRDYHMV
AVCEDSDSIGRLRKAIAREVANFKIQGQLVMGQLVPESYLELERRVLLERARVPGEFPVL
RHQYLLQLIQESQIQLEEAELPHAVHFLSEAGVLLHFDDPALQLRELYFIDPQWLCNIIS
QKLSLKSSGFWENPKGVVQRSMVERFLFESKCFPKCHLTQYFKLLEKFQIALPFGEDQLL
VPSSLSKHRPVIEMPHCENSEVIVRLYEMPYFPMGYWSRQINRLLEVSSYMLCGRERELR
PNRIYWRRGIYLSWSPEAYCLVEAANVEDNPASFVKITVPCSRKGRVLLGQVVDHVDSLL
EEWFPGLLATDIHGNGETLLKKWALYSFKDGQEWSKILLEDLFTHIDKDCLLVNPEDPRC
TVPISQIAPDLILSDQPAGIILDSEELEIDLTKENLLGDGGFGSVYRGIYKNEEVAVKIF
NKHASDLYIHRLLRQELVVLGRLHHPSLVGLLAAGAAPHLLVMELAPRGSLDSLFEHENS
SLNRKLQHRIALQVADGLRYLHSSMIIYRDLKPHNVLLFNLKTDSETIAKITDYGIAQCC
CSMGVRSSEGTPGFRAPEVARGNVIYNQQADVFSFGLLLYDLLTCGERISDGMKFPSEFD
EIAVQGKLPDPVRHHGCSPWPGFQGLMKDCMRENPQDRPTSTQVFERLNSGEMLCLMREL
VVSRAANAECFTVGYSSASNGPSSNPRAWVGGGSSTRRLGCVASVDLETEKVTTQVIDTS
PVLCLVTVQVPDEACDWLVAGTQSGALVMISTQNLSNWHNLQSVTDAVTSLFFHTQPQRS
QRKNYLLVGTANGILTVYEDSALQVENGQPVKTLHIGNVNTPVMCLGQSGHSLDRTTVWA
GCGTRILSFTADYGVCKTIDTKPNSLFQQHHAVSCEPCVSRMVVEKHVYLSKTGGQSVEV
WNKKSERMIDSIDCAKLLRHDSSRQPRKANSEFEFGADTPTWANIKSLLVQQTTTTLWIG
TRGGHLLLIELANLQLLQVISPHCQSIRSMASVFIETLNRKNVVLVLGRRLSQDKNQYDE
ESVLMVWNSSLPLEVKDLNKHCEMREEITAKMREQQND
NT seq
7677 nt
NT seq
+upstream
nt +downstream
nt
atggttaacaaggaagaactggaagaaagattgaaaaaactattagtgagattgaaaaac
ctacaggaggggaagcagttgagtaccctggttcagatcatccaagaccttcttttcctg
gcgcacactgatgactgtgcagcagagctatttgaggataaagatgtccatgtgcctctt
atggtggtgttgtcgacttacagcaacagcagaggggtgcaacaggtgggatggtcgttg
ctgtgtcggctgatggagatatgtccttccaccttggactcactggtcaggcccctggga
gcagggaaagactgggaggtacttggagtgcatcagcagatccttaaggtgttgtcccag
cacagtggagactgcagagtgatgatggttgggctcagggcactggctctgctcctcaga
tcagatgtgatcgtgttgttgattcgggatgaggaagaggatgtgtttagtttgatcgtt
gaggggatgaagactttcccctccagtgaggaggttcagattcagggctgccgtggtctc
cagctgctactggacagagtgtctgatgacgacctggtagagtttctggagaaccaggac
cacagtgtggttctaggtgctctccaccattttcacgacagtgaagacctgtttctgcag
gccatgaaggtactccttcctctagcaggtcctgccagtaacgtggagatcctgatgtcg
gggggagagaggtgttacagtgtggtggctggagccatggagtcgttcccagcggtcgag
gcactgcaggaggtcggctgctgtctgttcaggaagtttacatcagaaagatattgtagt
attctggtgctgaatggggtgcatagggtcactgtaagagcctgtttgacttaccctgag
aacgccactctacaagctgctgctctctcctgtctggctgccctcactgaaaccatagtg
cagagcaaagctgtggtgaatgaagggatggaggaggagaacagaggtaaggaggaggtg
gtggatgatgtggggttgtgctggatggaggcctgctgcagagctctggaggtccatgct
gctgattccacagtgcaggaagctgcatgttgggccatacacagcctgctattgcatggc
agcgagtcatggcaccattccacagaagagcaagacggaaggacaccagtccacagacag
atcatggctgccatgctgctccactcttcctcccctggggtgttccaggctgctgccagc
gccatgggaacactcatcacatacaatagtaaaatgcgatctctgttgttgtccaacggc
ctccatgtgaacgtggtggagatgatgaagagacatctgtcctctccagaggtctccgca
ggtggatgtaaactgctccacctgctcttcaagggaaggatggccagtctggatgaactg
gacatggccatgggtcagatccttagggccatgaaggtccataacttcatacctgaggtc
cagctggaagctctgagggccagcctggccttcctctgtcctgatcgaagtttgcgggtg
tctgatcacggtgtgtctgtggctgatccagacacagtggacgtgtctctgagggtgcag
aagaaccagagtgtggtggagggggcccacacagtctacctagagacactcaacaggttt
attagcagtgcagccatccaggagtgtggcctgcgtgttctgtctgccctggctgactgc
tctggtgctgtagacctgctctgtcaacagggggcgatagacactgtgctgcacacacta
cagatgttccctagggaacgagaaatacactactggggtctaaacctcctctgctgcctt
gtgtctaagaagaagctgtccagaatgatagtacccgtcctggcgtctgttctcgttacc
agtctcctgcagtacagggaggacacagagatgctgttaaaggggttccaggtggccctc
cgaatgctggatgcctgctcaggggcagcaggggagctgcagagggaaggctttgacaga
gagatcttcctccagctcaaagaaggaccacctgaccggtatagctacccgctctcccag
ctgcgtaaggctgcatgcctggccctgtccaagatgtgtggcgatgcagagctgaggtac
agtatgctggagaaggcctgtaaggacggggatgtgctcatggctgagtgtctcatccag
ctaggagccgacatcaacaagaagaccaagaccgagtcgctcatataccaggtgtgtgag
cagggcgggcctctgcagcttgtggtgctgcttctcagtcgaggggtccatgagcagcac
ctgcgtggggccctgggggccagcgtgcgtcgtggggacggccctgcgatcatccagcta
ctggggcgtctggggctggacctgaacaacaatgccctctgtctgggggggttcaggctg
ggtcgggtggatgctgcctggctcagccccctgctcgctgaacgaggtcgcgccaacagt
ctaccctccagcacaagtaagggtgcatgtttagctcggtacgtgttatccttccagagg
ggtaagacgacccctaccccctccacccccaggtctctagctgacccctgccttacctct
gggtacatgtcagacgagagtgatgactccagcttcctgtctttagaggacagtctggtc
ttcaacgacgatatggagagtgacggaagtgattcgcttttgttggcactgtccaccaat
gatttgtcggaggagtggaaggcagggtcacagaagaggaaaaacgggcgtcgcaggcac
tttagctccgagtcctgtatccatccgaagggagtccagggtgaggttgagctcaacgag
ccacttcagaggaggtatggcaggacaacccctaaccagaaaggtattcactccccagtc
ttgagctctgggtataactcctcccctctggtcggggacagagagtggatccgcctgctg
gacctatcagggaatgagctggactctgtgtcatgtttgttgggcgacggttctgtccga
cagcagctggagcacctgtatcgactagacttgagccagaacagcctatcagagttcccc
tctgggctgtgtgagagcttgaagagtctgacacgtctggatctccaaggcaaccagttg
cagtcgttgccggcagagcttctggccctgccctcactgaccatgctcaacgtgtcacgt
aactgtgtcggcccgcttctgacccttgaccccgccgtcacctgcccgtcgctacggcaa
ctcaacctgtcctacaaccacatcaccaccttcccccaccagctgggccgggccatggag
cgactggaggagctgtccctcgaggggaacagaatgagtgagctgtggtctcctctgtgt
cttctggagatgaagctcctagacatcagtaagaacagtgtggagagcatctcacgtgac
ttcctgtctggctgccccaaactagagaacttcagtgcttgtaccaaccatctcagttcg
ctgtcacatcttccctcaaagataacaactctgaagttatcacataacagtttcactacc
attcctcaagccgttctggatcttccaaatttacggtctgtggatatgaggaccaatgac
atcacagttttaccggggccgtgcacctgggcatcggtcaacctgcgggagctcatgttc
agtcagaaccgcatcggagtgctggacctgagtggacctgaagtttacaagtgggccaga
ctggagaaactacacctgagtgacaataagctcacagaggtccctcctcagatcggcctg
ctggaggagctgacctctctcgacttgagccgtaatggcggcctgcgctccttccctgac
gagatgggcaagctgagccggctgtgggatttgccactggatggcctgcgcctcagcctg
gatctcaagcacattggcaacaagaccaaagacatagtcaggttcctccagcagcgtctg
aagaaagccgttccgtactaccggatgaagctgattgtggttgggaatgccgacagtggt
aagactgctctgatccgacagctgatgaagctcaagcgttctcagtggcagatggagcgg
cccaccgctgggatcgacgtcagagattggaccatccgggaccgggataagaagaacatg
gtgctcaacgtctgggacttctcaggtggggaggagttcagtggttctcacccccacttc
cttaccccccgggccctctacctggttgtgtacgacctcagtaagggggctgcccaggtg
gacgcgctcaaaccctggctcttcaacatcaaggcggtggcccccctgtcaccagtcatc
ctggtggggacacacacagacgtgagcgaggacctccagctgcaggcttgcctggataag
atccgccaggagctcctcaaccaccagggcttccctgccatccgggactaccacatggtg
gcggtgtgcgaggactcggactccatcggcagactccgcaaggctatcgccagggaggtc
gccaacttcaagatccaagggcagctggtgatggggcagctggtcccagaaagctatttg
gagctggagagaagggtgctgctggagagggccagggtgccgggggagttccccgtgctc
agacaccaatacctgctacagctcatccaggagagccagatacagctggaggaggctgag
ctaccccacgctgttcacttcctcagcgaggccggagtccttctgcactttgacgacccg
gccctccaactccgagaactctactttatcgacccacagtggctttgcaacatcatctca
cagaaactgtctctgaaaagctctgggttctgggagaatcccaaaggcgtagtccagcgc
tctatggtggaacggttcctatttgagagtaagtgtttccccaagtgccacctgacccag
tactttaaactgctggagaagttccagatcgccctgcccttcggagaggaccagctccta
gtgccgagcagtctctccaaacaccggccagtaattgagatgccccactgtgaaaattct
gaggtcattgttcgtctctatgagatgccctacttccccatgggctactggtcgagacag
atcaaccgcctacttgaggtctcctcctacatgctctgtggcagagaaagagagctgcgt
cccaaccgtatctattggaggagaggcatctacctgagctggtctcctgaggcctactgt
ctggttgaggctgccaatgtagaggacaaccctgccagcttcgtcaagatcactgtgccc
tgctcacgcaaaggtcgtgtgttactgggtcaggtagtggaccatgttgactctctcttg
gaggagtggttccctggtctcctcgccactgatatccatggcaacggagagaccctgctg
aagaaatgggctctgtacagcttcaaggatggacaggagtggagcaagatactgctggag
gacctgttcactcacatagataaagactgtcttttggtaaacccggaggaccctcgctgc
acagtgcccatctctcagattgctccagacctgatcctcagtgaccagcctgctggaatc
atccttgacagcgaggagcttgagatcgaccttaccaaggagaatctgctgggggatggt
ggttttgggtctgtctatcgaggcatctacaaaaatgaagaggtggcagtgaagattttc
aacaagcatgcctctgatctctatatacaccgactactccgacaggagttggtggtgttg
ggtcgtctccaccaccccagcctggtggggctgctggcagccggggcggcccctcatctc
ctggtgatggagttagcccccagaggatccctggactctctgtttgaacacgagaacagc
agcctcaaccgcaagctccagcacaggattgctctgcaggtggccgacgggctcaggtat
ctccactcgtccatgatcatctaccgggacctgaagcctcacaacgtgctgctgttcaac
ctgaaaactgactccgagaccatcgctaagatcacagactacggcatcgctcagtgctgc
tgcagcatgggggtcaggagctctgagggcaccccaggtttccgggcgccagaggttgcc
cggggcaatgtgatctacaaccagcaggcagacgtgttctcattcggcctgctgctatac
gacctgctgacctgtggtgagcgcatctcagatggcatgaagttccccagcgagtttgac
gagatcgctgtgcagggcaagctgccagacccagtgaggcaccacggctgctccccctgg
ccaggcttccaaggcctaatgaaggactgtatgagggagaatccccaggacagacccacc
tccacacaggtgtttgagaggctgaactctggggagatgctgtgtctgatgagggagctg
gtggtcagcagagctgccaatgctgagtgtttcacggtgggctacagcagcgccagcaac
ggacccagttctaacccaagggcctgggtgggagggggcagcagcacacggagactgggc
tgtgtcgcgtctgtcgacctggagactgagaaagtcacaacacaggtgattgacacgagt
cctgtcttatgcctggtgactgtccaagtcccagacgaagcctgcgattggctggtggct
ggtacacaatcgggggcactggtcatgatcagcactcagaacctgtccaactggcacaac
ctgcagagtgtcaccgacgctgtgacatcactgttcttccacacacaacctcagcgcagt
caaagaaagaattacttgttagttgggacagcaaatggaattctgacggtttatgaggac
tctgcgctccaggtggagaatggccagccagtcaagacgttgcacatcgggaacgtcaac
accccagtgatgtgtctgggccaatcaggtcactccctggacaggaccacggtgtgggcc
ggctgtgggaccagaatcctttcctttaccgcagactatggcgtctgtaagaccattgac
actaaacccaacagcctcttccagcagcatcatgcggtgagctgtgagccgtgtgtgtct
cgtatggtagtggagaagcatgtgtacctcagcaagactggagggcagagcgtggaggtg
tggaataagaagagtgagcggatgattgacagcattgactgtgccaaactactcagacac
gactccagccggcaacccagaaaggctaattcagagtttgaatttggagcggatactcca
acctgggcgaatatcaagtccctcctggtgcaacaaaccaccactaccctgtggatcggc
acccggggaggccacctcctcctgatagagctggccaacctgcagctgctgcaggtcatc
agcccccactgccagtccatacgcagcatggcctctgtttttatagaaacactaaaccgt
aagaatgtggtcctggttttgggaagaagactgtcccaagataagaatcaatatgacgag
gagtctgtactgatggtgtggaacagttctctgcctctggaggtcaaggacctcaacaaa
cactgtgagatgagagaggagatcacagccaagatgagagagcagcaaaacgactga
DBGET
integrated database retrieval system
