Oncorhynchus nerka (sockeye salmon): 115146497 Help Entry 115146497         CDS       T07952                                  Name (RefSeq) ryanodine receptor 3-like   KO K04963   ryanodine receptor 3 Organism one  Oncorhynchus nerka (sockeye salmon) Pathway one04020   Calcium signaling pathway one04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:one00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     115146497    04020 Calcium signaling pathway     115146497  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:one04040]     115146497 Ion channels [BR:one04040]  Voltage-gated cation channels   Ryanodine receptor    115146497 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 SPRY RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_6 Med16_bridge Motif Other DBs NCBI-GeneID:  115146497 NCBI-ProteinID:  XP_029544460 LinkDB All DBs Position LG18:complement(32434213..32515388) Genome browser AA seq 4484 aa AA seqDB search MESEIVRDLDCLGGKNRASVALPIEEVHQTLYDLITYFQLPDAELEHEEKQIMLRSLKNR QNLFKQEGMLTLVSCCIDRLNVYNSAAHFGECAGAEAGASWKEILNLLYELLAALIRGNR NNCTQFSNNLDWLVSKLERLESSSGILEVLHCILTESPEALNIIQRGHIKSIISLLYKHG RNHKILDVLCSLCVCNGVAVRANQNLICDHLLPKRDLLLQTRLVNDVQSMRPNIFLGVSE GSAQYKKWYYELTIDQVDHFLTSDPSHLRVGWATNKGYAPYPGGGEGWGGNGVGDDLYSY GFDGLHLWSGRISRAVASNNQHILTSEDVVSCCLDLGAPSISFRINGQPVQGMFENFNID GLFFPVVSFSAGVKVRFLLGGRHGDFKFLPPSGYAPCYEALLPKEKVKVEPVKEYKRDME GVRDLLGTTQFMSQASFIPTPVETSQIVMLPYLEKVRDRLAENIHELWAMNKIELGWSYG KIRDDNKRHHPCLVDFSKLPETEKNYNLQMSTETLKTLLALGCHVVQVNANAEEDLKKIK LPKNYMMSNGYKPTPLELSDVKVTPGQELLVEKLAENAHNVWAKDRIKQGWTYGIQQDVK SKRNPRLVPYSLLDERTKKSNRDSLREAIRTLIGYGYNIEPPDQDGAGHVVERLSIDKIR FFRVERTYAVLTGKWYFEFEAVTGGDMRVGWARPGCKPDVELGTDELAFVFDGYKGHRLN MGSRFFGRCWQAGDVVGCMINMEDKSMIFTLNGEILITNKGSELCFADFETEDGFIPVCS LGLSQVGRMNLGKDASTFKYYTMCGLQEGFEPFAVNMNREVTMWFSKRLPTFFNVPKNNN HIMVTRIDGTIDSPPCLKVSHRTFGTQNSNGDMVYCRLSMPVEFHTFFKTSPVMDMNGVH EEHESLKLKHRHPLKSMRHSHDGIRGTDYSNITTYYYSVRVFAGQDPSCVWVGWVTPDYH YYSNQFNLSKNRTVTVTLGDERGRVHESVRRSNCYMVWGGDATSSGHSSSRSNVDLEIGC LIDLATGLVTFTVNGKELATSYQVEPNTKLFPAVFVRPTSPNLFQFELAKIKNTMPLSAA IFKSEHKNPVPQCPPRLDVQTINSVLWSRMPNTFLKVETARVSERHGWVVQCLEPLQMLA VHIPEENRCVDIMELSEQEDLRTFHYHTLKLYCALCALGNTRVAHALCSHLDQSQLLYTI DNQYLSGMLREGFYNVLISVHLETAKEARLMMNNEFIIPVTAETRSIRLFSDATKHHSPP GVGLSTSLKPRLNFYPPCFISTKREQQLYSPQIPLDALKEKAITMLTEAVQGGGHHIRDP VGGSVEYQFVPILRLIGTLLTMGVLGSQDVHKILLLIDPNVFAEHHEEAATAVTEAAEKE GLTGAEEKAVEAGEEEAAKEAKQPIKGLLEKRLPEPVKRQMCELLHYFCDCELKHRIEAI VSFSDSFVSKLQYNQKFRYNELMLALNMSAAITAKKTKEFRSPPQEQINMLLNFSTGEDC PCPEDIQEELYAFHNELRLHCGIPMEEEEDDQDTSIKGRLLALVYKVKGQPLKTEEEPTE QEQQAPSNLKELISQTMVSWAQECHVQDPELVRVMFSLLRRQYDSIGELLRAMRKSYTIS AASIQDTINLLASLGQIRSLLSVRMGKEEEKLMIDGLGDIMNNKIFYQHPNLMRVLGMHE TVMEVMVNVLGGGKSQEIAFPKMVASCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGL ASPAMRGSTPLDVAASSVMDNNGLALALEEPDLDKVVTYLAGCGLQSCPMLLDKGYPDIG WNPIEGERYLFFLRFAVFVNGESVEENSSVVVKLLIRRPECFGPALRGEGGNGLLAAMKE AIKISDNPAVDLPSSAQGVSSDASAEDDEEEEVVHMGNAIMSFYSALIDLLGRCAPEMHL INKGKGEALRIRAILRSLVPTEDLVGIISIPLKMPVVHKDGTVTEPDMAASFCPDHKAPM VLFLDRVYGIEDQSFLLQLLDVGFLPDLQASASLDTEVLSTTETALAMNRYIGSAMLPLL TRCAPHFAGTEHYAVLIDSTLHTIYRLSKGRSLTKAQRDAIEECLLAVCKYLRPSMLQHL LRRLVFDVPLLTEYCKMPLRLLTNHYEQSWKYYCLPSGWGSYGMASDEELLLTKKIFWGV LDSLSQRKYDADLFKMAMPCLSAISGALPPDYIDATISTTLEKPVSVDAQGNFDPKPIST ANISLPEKLEHVANKYAEHSHDKWSAEKVMLGWRYGDCIDEKAKTHPLLRTYKGLTEKEK DIYRWPVRETLKSMLAMGWNIDRTKDGETMSLRESEKMRKISQSSSHANGFNPTPIDTIN VVLSRELQGMVEVVAENYHNIWAKKKKNDLGIRGGATHPLLVPYDTLTAKEKARDKEKAR DLFRFLQINGYAITRGLKDMEQDSCSMEKRFAYKFLKKLLKYVNSAQEFIAHLETMATSG KTDKSPHEQEIKFFAKVLLPLIDQYFKNHCLYFLSSPSKNLSSSGYASNKEKEMATSLFC KLAALVRHRISLFGSDSTTMVSVLHILAHTLDTRTVMKSGSELVKAGLRTFFENAAEDLE KTLENLKLGKFTHSRSQMKGVSQNINYTTVALLPILTALFEHITQHHFGVDLLLDDVQVS CYRILTSLYALGTGKNIYVERQLPALGECLATLAGAMPVAFLEPLLNKHNPCSVFNTKTA RERAILGMPDAVEEMCPEMPRLDVLMKDINDMSESGARYTEMPHVIEVVLPMLCNYLSYW WEKGPENQASPHSGGSVGGSVFSTTVTSEHLSLILGNILKILNSNLGIDEASWMKRIAVY AQPIITKARAVLLKSHFLPTLEKLKKKTVKVVSEEELLKADSKGDTQEAELLILDEFAVL CRDLYAFYPMLIRYVDNNRSRWLKEPDADSNELFRMVAEIFILWCKSHNFKREEQNFVVQ NEINNLSFLTGDSKIKMSKSGGQDQERKHKRKRGEFYSIQTSLIVAALKKMLPIGLNMCT PGDQELISLAKTRYILKDTDDEVKEHLRQNLHLQEKSEDPAVRWQLNLYKDVMVKNEGPP DPERTVFRVQSISAAVFHLEQVEQPLRSKKCVWQKLLSKQRKRAVVACFRMAPLYNLPRH RSINLFLLGYQRIWIETETYSFEEKLVQDLATQLKVEEEEEEEAEMQPDPLHQLILHFSH NALTERSSLEEDPLYIAYADMMAKSCAEDEEEEDEGKEKTFEEKEMEKQKTLYQQARLHD RGAAEMVLQMISASKGSLGPMVTFTLKLGISILNGGNILVQQKMLDYLKEKRDAGFFKSL SGLMQSCSVLDLNAFERQNKAEGLGMVTEEGSINVSERGSKVLQNDEFTKDLFRFLQLLC EGHNNDFQNFLRTQTGNTTTVNIIISTVDYLLRLQESISDFYWYYSGKDIMDEAGQRNFS KALAVAKQIFNSLTEYIQGPCIGNQQSLAHSRLWDAVVGFLHVFANMQMKLSQDSSQIDL LKELLDLQKDMIVMMLSLLEGNVVNGTIGKQMVDTLVESSSNVEMILKFFDMFLKLKDLT SSDNFKEYDPDSKGVISKKEFQKSMENQKQYSQSEIEFLLSCVEADENDMFNYEEFVERF HEPAKDIGFNVAVLLTNLSEHMPHDARLATFLDLAESVINYFEPYLGRIEIMGGAKRIER VYFEISESSRTQWEKPQVKESKRQFIFDVVNEGGESEKMELFVNFCEDTIFEMQLASQIS EPDSVERLEEDEEDSHSVEEEGEEEEEESMMESHSAFTNSCVSMRKNLSSFRQLLTFKSM RRQYRNFRKMSVREMVRGLFSFFWKIITGLFRFLYNLVWGFFHILWSSMFGGGLVEGAKN MKVTDILGNMPDPTQFGIHGDVLEAEKMEASEASSVAEMVQMAQVDKAEADLMAELLNIQ TKSQGGKHAAEPGLGDMGEVVGVDAPSLATAVKQKKAKEASTMEPANGDHKAKPEKADPE DEEKKDKDEAKEETPPESPPEEEKKAPKKRPGLKKEPPEAFMARFFSGLEIYQTKMLNYL ARNFYNLRFLALFVAFAINFILLFYKVTGDDGDDDDPGPWNGGGGTDEEEDEGGMEYFVL QESTGYMAPTLRFLAILHTVISFLCVVGYYYLKVPLTVFKREKEIARKLEFDGLYITEQP SDDDIKGQWDRLVINTPSFPNNYWDKFVKRKVINKYGDLYGAERIAELLGLDKSALDFNP TEETVVKEASLVSWLSSVDTKYQCWKMGVVFTDNSFLYLVWYTTMSILGHYNNFFFAAHL LDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDENQPD MKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDPYELYRILFDITFFFFVIVILLAIIQ GLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDTTPHGFETHTLQEHNLANYLFFLM YLINKDETEHTGQESYVWKMYQERQWDFFPAGDCFRKQYEDQLG NT seq 13455 nt NT seq  +upstreamnt  +downstreamnt atggagagtgagatagtgagagacctagactgtctggggggtaagaaccgtgcatcagta gccctgcccatcgaggaggtccaccagactctctacgacctcatcacctatttccagctg cctgatgctgagctggagcacgaggagaaacagatcatgctgcgctctctcaagaaccga cagaacctcttcaaacaggaaggcatgctgactctggtgtcctgctgcatcgaccgtctc aacgtgtacaacagtgcagcccactttggggagtgtgccggggcagaggctggggcttcc tggaaggaaatcctcaacctgctctatgagctgctggcggcgctgatccgaggcaacagg aacaactgcacccagttctccaacaaccttgactggctggtcagcaagctggagagactc gagtcctcctcaggcatactggaggttctccactgcattctaactgagagcccggaggct ctaaatatcatccagagaggacacatcaagtccatcatctccctgctctacaaacatgga cgcaaccacaagattctggatgtgctctgctccctctgtgtgtgtaacggggtggctgta agagccaatcagaatcttatctgcgatcacctgctccctaaaagagatctgcttctccag acccgattggtcaatgacgtccaaagcatgaggcccaacatcttcctgggagtgagtgag ggctcggcccagtataagaagtggtactacgagctgacgattgaccaggtggaccacttc ttgaccagcgacccctctcacctgcgtgtgggctgggccaccaacaagggttacgcccct taccctggtggaggggagggctgggggggcaacggggtgggggacgacctctactcttac ggctttgacggacttcatctctggtcaggtcgtatctcccgggcggtggcttctaataac caacacatcctgacctctgaggatgtggtgagctgttgtctggacctgggagctcccagc atctccttcaggatcaatggacagcccgtacagggcatgttcgagaacttcaacatcgat ggactcttcttccctgttgtcagcttctctgctggcgtcaaggtgcgtttcctgttgggc ggtcgtcatggcgacttcaagttcctgcctccgtcaggctacgctccgtgttacgaggcc ctgctccctaaggagaaggtgaaggtggagccagtgaaggagtacaagagggacatggag ggggtccgagacctgctggggaccacacagttcatgtcccaggcctccttcatacccacc cctgtggagactagccagatcgtcatgctgccatacctggagaaggtccgggacagactg gctgagaatatccacgagctgtgggccatgaacaagatagaactgggctggtcttatggg aagataagggacgataataagcggcatcacccctgccttgtggatttttccaaactgcct gaaacagaaaagaattacaacctgcagatgtcaactgaaaccttgaagaccctgctggca ttaggctgccatgttgtccaggtcaacgccaacgctgaagaggacctgaagaagatcaaa ctcccaaaaaactacatgatgtcgaatggttacaagcccacaccgctggagctgtctgac gtgaaagtgaccccaggtcaggagctcctggtggagaaactggcggagaacgcccataac gtgtgggccaaggacaggatcaaacagggttggacctacggcattcagcaggatgtgaag agtaagaggaaccctcgcctggtgccatattctttattagacgagcgcactaagaagtcc aacagggacagcctccgtgaggccatccgcactctgattggatacggatacaacatcgaa cctcccgaccaggatggcgcaggccacgtggtggagagactgagcattgacaaaatacgc ttcttccgtgtggagagaacgtatgcggtgctgacagggaagtggtactttgagtttgag gcggtgacgggaggtgacatgcgtgtgggttgggccagacctggatgtaagccggatgta gagctgggtactgatgagctggctttcgtctttgatggatacaagggtcaccgtctgaac atgggcagccgtttctttggccgttgttggcaggcaggggatgtggtgggctgcatgatc aacatggaggacaagtctatgattttcaccctcaatggagagatcctcatcaccaacaag ggctccgagctctgcttcgccgacttcgagacggaggacggttttatcccagtatgtagt ctgggcctgtcccaggtgggtcgtatgaacctggggaaggatgccagtacctttaagtac tacaccatgtgtggtctccaggagggctttgaacccttcgccgtcaacatgaaccgtgag gtcaccatgtggttcagcaaacgcctccccacctttttcaatgtgccaaagaacaacaac catataatggtgaccagaatagatggcaccatcgacagccctccctgtctgaaggtgagt cacaggacgtttgggacccagaacagtaatggtgacatggtatactgtcgtctgagcatg cccgtggagttccacaccttcttcaagaccagccctgtcatggacatgaacggagtgcac gaagagcacgagtccctcaaactcaaacacagacatccactgaagtccatgagacacagt catgacggaataagaggaacagattacagcaacatcaccacgtactactactctgtcagg gtattcgctggtcaggatccatcctgcgtgtgggtgggctgggtcaccccagactaccat tactatagcaaccaattcaacctcagtaagaaccggacggtgacagttacccttggagac gagcgtgggcgggtccacgagagtgtgaggaggagtaactgctacatggtgtggggaggg gatgccaccagctcaggccactcgtccagtcgcagtaatgtggacctggagataggctgc ctcattgacctggccactggcctggtgaccttcactgtcaacggcaaggagctggccacc tcctaccaggtggaacccaacacaaagctgtttcctgctgtgtttgtgcgaccgaccagc cccaatctcttccagtttgagctggccaagataaagaacaccatgcctctgtcggcggcc atctttaagagtgaacataagaacccagtgcctcagtgccctccgaggctggacgtccag accatcaactcagtgctgtggagccgcatgcccaacactttcctaaaggtggagacagcc agggtcagtgagagacacggctgggtggtgcagtgtctggagcccctccagatgctggct gtgcacatacctgaggagaacaggtgtgttgacatcatggagctgtctgagcaggaggac ctgaggacgttccactaccacaccctgaagctctactgtgccctgtgtgcactgggtaat acccgtgtagcacacgccctctgcagccacctagaccaatcccagctgctctacaccatc gacaaccagtacctgtcgggcatgctgcgtgagggcttctacaacgtcctgatcagcgtt catctggagacggccaaggaggcccgcctcatgatgaacaacgagttcatcatccctgtc actgccgagactcgcagcatccgcctgttctccgatgccaccaagcaccactctcctccc ggcgtgggcctcagcacctccctgaagccccggctcaacttctaccctccctgtttcatc agcaccaagagggagcagcagctgtacagcccccaaatccccctggatgccctgaaggag aaggccatcaccatgctgaccgaggccgtacagggcggtgggcatcacatcagagaccct gtagggggcagcgtggagtaccagtttgtgcccatcctgaggctgattggcacgctgctc accatgggcgtgctgggcagtcaggacgttcataagatcctgctgcttatcgaccccaac gtgttcgcggagcatcacgaggaggcggccaccgcggtgacggaggccgcagagaaggag ggactgacaggtgccgaggagaaggcagtggaggccggggaggaggaggctgccaaagag gccaagcagccaatcaaaggtctgctggagaagaggctgcctgagccagtcaaacgacag atgtgtgagctgcttcactacttctgtgactgtgagctgaagcatcgcattgaggccatc gtgtccttctcagacagctttgtctccaagctgcagtacaaccagaagttcaggtacaac gagctgatgctggccctcaacatgtctgctgccatcaccgccaagaagaccaaggagttc cgctcccctccccaagaacagattaacatgctgttgaacttcagtacgggggaggactgc ccgtgtccagaggacattcaggaggagctctatgccttccacaacgagctgcggctgcac tgtggaatccctatggaggaagaggaagatgaccaggacacgtctattaaaggtcgtctg ctggccctggtctacaaggtcaaaggtcaacctctgaagactgaagaggagcccacagag caggaacaacaagccccctccaacctgaaggagttgatctcccagaccatggtgagctgg gctcaggagtgccacgtccaggaccccgagctggtcagagtgatgttcagcctgctgagg agacagtacgacagcattggagagctgctccgggccatgaggaagagctacactatcagt gctgcctctatacaggataccatcaacctgctggcctctctgggtcagatcagatcactg ctatccgtacgcatgggcaaggaggaggagaaactcatgatcgacggtctgggtgacatc atgaacaacaagatattctaccagcaccccaacctgatgcgtgttctaggcatgcatgag acggtgatggaggtgatggtcaacgtgctgggaggaggcaagtcccaggagatagcgttc cccaagatggtggccagctgctgtcgcttcctgtgttacttctgcaggatcagtcgtcag aaccaaaaggccatgtttgaccacctcagctaccttctggagaacagcagcgtaggcctt gcatccccagccatgagaggctcgactcctctagacgtggctgcctcctctgtgatggac aacaacggcctggccttggccctggaagagcccgacctggacaaggtggtgacgtaccta gcaggctgtgggctccagagctgtcccatgctgctggacaaaggttaccctgacatcggc tggaaccccattgagggtgaacgctacctcttcttcctgcgcttcgctgtatttgtcaat ggtgagagtgtggaggagaactccagtgtggtggtgaagctactgatcaggcgtccagag tgttttggtccggctctgagaggagaggggggtaacgggctgctggcagccatgaaggag gccatcaaaatctcagataaccctgctgtggacttgccctcctccgcccagggggtcagc tctgacgcgtctgctgaggacgatgaggaggaagaggtggtgcatatgggcaatgccatc atgtccttctactctgccctcatcgacctactgggacgctgtgccccagagatgcacttg atcaacaaaggtaaaggggaggccctgcgaatccgtgccatcctgcgctcccttgtgccc actgaagacctggtgggcatcatcagcatacccctcaaaatgcctgtcgtccacaaagac ggcactgtgacagagcctgatatggcagccagtttctgcccggaccacaaggcccccatg gtgctgttcctggacagggtctatggtattgaggaccagagctttctacttcagctgctg gacgtgggcttcctgcccgacctgcaagcctctgcttctctggacacggaggtactcagc accacagagacagctctggccatgaacaggtacatcggctctgccatgctgcccctgctc acccgctgtgccccccacttcgctggcacagagcactatgccgtgctcatcgactccacg ctgcacaccatctacaggctgtccaagggccgctcgctcaccaaggcccagagagacgct atcgaggagtgtctgctggccgtctgcaagtacctccgtccctccatgctgcagcatctc ctgcgacgcctcgtctttgacgtgcccttgctgacggagtactgcaagatgcctctcagg ctcctgaccaatcactacgagcagagctggaagtactactgtctgccatcaggctggggc agctacggcatggcctcagacgaggagctgctcctcacaaagaagatcttctggggtgtc ttggattcgctctcacagaggaagtacgatgcagatctctttaagatggccatgccctgt ctgagtgccatatctggggccttaccgcctgactacatagacgccaccatcagcaccacc ctggagaagcctgtgtctgtggacgctcagggcaacttcgaccccaaacccatcagcact gccaacatatctcttccagagaaactggaacacgttgccaacaaatatgctgagcattcc catgacaaatggtcagccgagaaggtgatgttgggatggaggtatggggactgtatagat gagaaggccaagactcaccctctactcaggacctacaaaggtctgacagagaaggagaag gatatctacaggtggcctgtgagggagactctgaagagcatgctggctatgggctggaac atcgacaggaccaaggacggagagaccatgtccctacgggagagtgagaagatgcgcaag atctcccagtcctcctctcatgctaacggtttcaacccgaccccaatagacaccatcaat gtggttctgtctagagagttacagggcatggtggaggttgtggctgagaattatcacaac atctgggctaagaagaaaaagaatgaccttggaattagaggtggggcaactcaccctctg ctggtgccctatgacaccctgaccgccaaagagaaggcccgggacaaagagaaggcccgg gacctgttccgcttcctgcagatcaacggctacgccatcaccagaggtctgaaggacatg gagcaggactcttgctccatggagaagaggtttgcctacaagttcctcaagaagctgctg aagtatgtgaactcagcccaggagttcattgcccaccttgagaccatggctaccagtggg aagaccgacaagtcgcctcatgagcaagaaatcaagttttttgccaaagtcctcctccct ctgatagaccagtacttcaagaaccactgtctctacttcctgtcttctcccagtaagaac ctgagcagcagcggctacgcctctaataaggagaaggagatggccaccagcctgttctgt aaactggcagctcttgtcagacacaggatttccctatttgggagtgactccaccaccatg gtgagcgttctccacatcctggcccacacactggacaccaggacggtgatgaagtctggc tcagagctggtgaaggcggggttaaggacgttcttcgagaacgcagcggaggacttggag aagacacttgagaacctgaagttggggaagttcacccactcccgctcacagatgaagggc gtgtcccagaacatcaactacaccacggtggcactactgcccatcctcactgccctgttt gaacacatcacccagcaccactttggagtggacctgctcttggatgatgtccaagtgtcc tgctatcgtatcctgaccagcctctatgcgctcgggactgggaaaaacatctatgtggaa aggcagctgccggccctgggggagtgtctggccaccctggcaggggccatgcctgtggcc ttcctggagcccctgctcaacaaacacaacccctgctctgtgttcaacaccaagaccgcc agagaacgggccatcctgggcatgccagacgcggtggaggagatgtgtccggagatgcct cgtctagacgtcctgatgaaggacatcaacgacatgtctgagtctggggcgcgctacaca gagatgccccacgtcatcgaggtggtgctacccatgctgtgtaactacctgtcctactgg tgggagaagggcccagagaaccaggcgtctccgcacagcgggggaagtgttgggggcagt gtcttctccaccaccgtcacctcagaacacctcagcctcatcctgggaaacatcctgaag atcctcaacagcaacctgggcatcgacgaggcctcctggatgaagaggatcgcagtgtac gcccagcccatcatcactaaggccagggctgttctgttgaagagtcacttcctgcctaca ctggagaagctgaagaagaagacagtgaaggtggtgtcggaagaggagctactgaaggct gacagtaagggagatacccaggaggctgagctcctcatcctggatgagttcgctgtgctc tgcagagacctctacgccttctacccaatgctcatccgctatgtagacaacaacaggtcc aggtggctgaaagaaccagacgctgactccaatgaactcttcagaatggtggctgagatc ttcatcctctggtgcaaatcacataacttcaaaagggaagagcagaactttgtggttcag aatgaaatcaacaacctgtcattcctgactggtgatagcaagatcaagatgtcaaagtca gggggtcaggaccaggagaggaagcataagaggaaacgaggagagttctactccatccag acctccctgatcgtggctgccctgaagaagatgctgcccattggactcaacatgtgcacc cccggggaccaggagctcatctccctggccaagacacgctatatcctgaaagacacagat gatgaagtgaaggagcatttgcggcagaatctgcaccttcaagagaagtcagaggaccct gcagtgcggtggcagctgaacctgtataaggatgtgatggtgaagaacgaggggcctcca gaccctgagagaacagtgttccgggtccagagcatctcagctgcagtctttcatctggag caggttgagcagccgttgaggtctaagaagtgcgtgtggcagaagctgctgtccaagcag agaaagcgtgcggtggtggcctgcttccgcatggctcctctctacaacctgcccaggcat cgctctattaacctcttcctcctgggctatcagagaatatggatagagacagagacgtac tcttttgaagagaagctagtgcaggacctggcaacccaactgaaggtggaggaggaggaa gaggaggaggcagagatgcagccagaccctcttcatcagctcatcctgcatttcagtcac aatgcgctcactgagcggagttctttggaagaggatcctttgtatattgcatatgcagac atgatggcaaagagttgtgcagaagatgaagaagaggaagatgaaggaaaagagaaaacg tttgaggaaaaagagatggagaaacagaagactctgtaccagcaggccagactgcatgac agaggagctgctgagatggtgttacagatgatcagtgccagcaaaggttcacttgggccc atggtgacctttaccttgaagctgggcatctctatactcaacgggggcaacatactggtt cagcagaaaatgcttgactatctgaaggaaaaaagagatgctggctttttcaagagttta tcaggactcatgcagtcttgcagtgtcctggatttgaatgcattcgaaaggcaaaacaaa gcagaaggtcttgggatggtgactgaggaaggatcaatcaacgtgagtgagcggggttcc aaggtactgcagaacgatgagttcactaaggatctgtttaggtttctgcaattgctctgc gagggacacaacaacgacttccaaaacttcctgcggactcagacagggaacacgaccaca gtaaatatcatcatcagcactgtggactacctgctccgtctgcaggaatccatcagtgat ttctactggtactactctgggaaagacatcatggatgaggctggccagcggaacttctcc aaagccctggctgtggccaagcagatcttcaactctctcactgagtacatacagggcccg tgtattgggaaccagcagagtctggcccacagcaggctatgggatgcagtggtgggcttc ttgcatgtgtttgccaatatgcagatgaagctctcacaggactcaagtcagattgactta ttgaaggagctgctagacctgcagaaggacatgattgtgatgatgctctcccttctggaa ggtaatgttgtcaacggaaccattggcaaacagatggtggacaccctggtggagtcctcc agcaatgtagagatgatcctcaagttcttcgacatgttcctcaaactcaaagacctgacc tcctcggacaacttcaaggagtacgacccggacagcaagggagtgatctccaagaaggag ttccagaagtccatggagaaccagaagcagtactcccagtcagagattgagttcctgctc tcctgcgtcgaggctgacgaaaacgacatgttcaactacgaggagtttgttgaacgtttt catgaaccggccaaggacattggttttaacgtggcggtcctgctcaccaacctatcagaa cacatgcctcacgacgcccgtctagccaccttcctggacctggctgagagcgtaatcaac tacttcgagccctacctgggccgcatcgagatcatgggcggggccaagcgcatcgagagg gtctactttgagatcagtgagtccagtcgtacgcagtgggagaaaccccaggtcaaagag tccaagagacagttcatctttgacgtggtcaacgagggcggggaaagcgagaagatggag ctgtttgtcaacttctgtgaggacaccatctttgagatgcaactggcctcccagatctct gagcctgactcagtggagcgtctcgaggaggatgaggaagacagccacagtgtggaggag gaaggggaggaggaagaggaggagagcatgatggagtctcactcagccttcacaaactcc tgtgtctccatgaggaagaacctgtccagcttccgccagctgctcaccttcaagagcatg cggcggcagtacaggaatttcaggaagatgagtgtgagggagatggttcgagggttattc tccttcttctggaagataatcacgggcctcttccgcttcctctacaacctggtgtggggc ttcttccacatcttgtggtcctccatgtttggtgggggcctggtggaaggggcaaagaac atgaaggttacagacatcctggggaacatgcctgaccccacacagtttggtatccatggc gacgtgctggaggcagagaagatggaggcgagcgaggcatcgtcggttgcagagatggtc cagatggcccaagtggacaaggcagaggccgacctgatggctgagctgctcaacattcaa accaagagccaggggggcaagcacgcagccgagccaggtctgggggacatgggggaagtg gtgggggttgacgccccctctttagccactgccgtcaaacagaagaaggccaaggaggct tctactatggagcctgccaatggagatcacaaagccaagccagagaaggcagacccagaa gacgaggagaagaaagacaaggacgaagccaaagaggagactccacctgagtccccacca gaagaggagaagaaggcccccaagaagagaccgggactaaagaaagagcccccagaggcc ttcatggccagattcttctctggcctggagatctaccagaccaagatgttgaactatctg gccagaaacttctacaacctgcgtttcttagcgttgttcgttgctttcgccatcaacttt attctgctcttctacaaagtgactggcgatgatggggatgacgatgatccaggcccctgg aacggtggtggaggtactgatgaagaggaggatgaaggtgggatggagtattttgtcctg caggagagcaccggctacatggcacctacactgcgcttcctggccatattacacacagtc atctctttcctgtgtgtggtgggatactactacctgaaggtgcctctgacggtgttcaag agagagaaggagatcgccaggaagctggagtttgacggcctctacatcacagagcagccg tcagacgatgacatcaaaggacagtgggaccgcctcgtcatcaacaccccttccttccct aataactactgggacaagtttgtgaaacgcaaggtgatcaataagtatggagatctgtat ggagcagagaggatagcagagctgctggggctggacaagagtgctctggacttcaacccc acagaggagacagtggtgaaggaggcatcgctggtgtcctggttgagctctgtcgacacc aagtatcaatgctggaaaatgggtgtggtgtttacagacaattcgttcctgtacctggtg tggtacaccaccatgtccatcctgggtcactacaacaacttcttcttcgctgcccatctg ctggacatcgccatgggcttcaagaccctccggaccatcctgtcctcagtcacccacaat ggcaaacagctggttctgactgtaggtctactggcggtggtggtgtatctgtacactgtg gtggccttcaacttcttccgcaagttttacaacaagagtgaggatgagaaccagccggat atgaagtgtgacgacatgatgacttgctacctgttccacatgtatgttggtgtgagggca gggggtggcatcggagacgagatagaagaccctgcgggcgacccctacgagctctaccgc atcctcttcgacatcaccttcttcttcttcgtcattgtcatcctgctggctatcatccag ggtctgatcattgatgcttttggagagctgagagaccaacaggagcaagtgaaagaggat atggagaccaaatgtttcatctgtggcatcggcaatgactactttgacaccacgcctcac ggctttgaaacacacaccttacaagagcacaacttggctaactacctgtttttcctgatg tacctcatcaacaaagatgagacagaacacactggccaggagtcatacgtgtggaagatg taccaggagaggcaatgggactttttccccgctggagactgtttcagaaagcagtatgag gatcagcttggatag

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