Oreochromis niloticus (Nile tilapia): 100693798
Help
Entry
100693798 CDS
T06104
Symbol
lrrk2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2 isoform X1
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
onl
Oreochromis niloticus (Nile tilapia)
Brite
KEGG Orthology (KO) [BR:
onl00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
onl01001
]
100693798 (lrrk2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
onl04131
]
100693798 (lrrk2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
onl04147
]
100693798 (lrrk2)
Enzymes [BR:
onl01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
100693798 (lrrk2)
Protein kinases [BR:
onl01001
]
Serine/threonine kinases: TKL group
LRRK family
100693798 (lrrk2)
Membrane trafficking [BR:
onl04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
100693798 (lrrk2)
Exosome [BR:
onl04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
100693798 (lrrk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
LRR_4
LRR_8
Roc
COR-A
Ras
COR-B
LRR_14
WDR55
Ank_2
Ank_3
Beta-prop_WDR3_2nd
TFCD_C
Beta-prop_RSE1_2nd
LRR_9
Beta-prop_WDR36-Utp21_1st
Beta-prop_EML_2
LRR_13
AAA_16
NACHT
Kdo
AAA_22
Gtr1_RagA
Ank_4
Beta-prop_THOC3
Arf
nSTAND3
Viral_helicase1
UNC45-central
SRPRB
AAA_7
DUF7079
PduV-EutP
Spt5_N
Septin
Beta-prop_BBS7
Motif
Other DBs
NCBI-GeneID:
100693798
NCBI-ProteinID:
XP_005454224
Ensembl:
ENSONIG00000003823
LinkDB
All DBs
Position
LG7:complement(42265744..42296263)
Genome browser
AA seq
2533 aa
AA seq
DB search
MVNKEELEERLKKLLVRLKTPQEDRQLCTLIQIIQDLLFLAHTDYAAELFEDKDVHVPLV
LVLSTHISSRGVQQVGWSLLCQLIEICPTTLDQLTRPLDEAQEWEVEGVHQQILKVLSQY
SADCRVTMVALRALALLLRSAKIPLLVLLEEEEDVFGLVVYAMKAFPTSEEVQLQGCTAL
QLLLEEVSDDHLVEFVENQDHAVVLAALKRFPDNSEMQLQALKALLPLAHPGSNVEVLMS
GGTRCYSTIIAAMDAFPEVEELQEKACSLFKRFTSESYNDILVRNGVHRVAVRACQTFPN
NAKLQAAALSCLANLTATIVQNKAVAEQGLEEGEEEENRGNGQVEDMELSWMKECFTALE
LHADEPGVQEAACWAIHSLLLHGAALNHLEEEQDERTPVYRQLMAAMLLHFASPNVFNAA
TSAIATLITNNSKMRSLLLSSGLHVNLVEMMKRHSDSAEVSISACKLLNLLFQGRTASLD
ELTMAMNQILSTMKFHNFNLEVQLEALQASLVFLCPDRSLREHGNSVADPDMADVSLKVL
KNQCVVEGAHILYLEALNRFISSSAIQTCGLKVLSALADCSGAVDLLCQQGAIDTVLHTL
QMFPQEREIHYWGLTLLTYVVSKKKLSRMIVPVLASVVVTALIQYREDSEMLLKCLQVAL
RMLDACSGAAAELQKEDFDRHIFQCLREETDQSISPLRKSVCLALSKMWCDSELHYSMLE
KACMDGDTTMAECLIELGADINKKTKNESLIYQVCERGGPLELVELLLSRGCHEQHLRRA
LAVSVKRGDGPTVIQLLGRLGLDLNNNALCLGGFRLGRLDAAWLSPLLGERSRTYSLRYN
NTKGPSLAKYIQFLQRAKSVNCPPRSVTDPCLTSGYISDESDDSSFSFTSLEDGLFFNDD
MESDGSDSLSGALSPKSYNNSSEELRGESLRRKQGRRRHASAESGQTESEHTEPLHRRYG
RNSSSQKVLGSAENSAALPKEKERIHLLDLSGNELNSLSCLNDGFVQQQLWHIHRLDLSY
NCLLEFPSELCLSLKNLTRLDLQGNQLQSLPQELLSLPSLSMLNASRNCVGPQLTFDPEV
TCPKLKQLNLSFNKITTFPFELGRTMHTLEELYMEGNCITELCTPLCLPEIKLLDVSKNG
VENISADFLRSCPKLETLNVSMNKLCSLSRLPSKIMTLKLANNSFASIPEAVLELPVLRS
VDMRTNSIVVLPGPASWVSSIIRELMFSQNCIQTLDLSGPIHKWTRLEKLHLSANRLTEI
PPQIGLLEGLTSLDVSHNTNLRSFPDEMGKLSRLWDLPLDGLQLQLDLKLTGSKTKDIVR
FLQQRLKKAVPYYRMKLIVVGNAGSGKTSLIQQLMKLKRSQLNSKQTSFGIDVRDWTVRE
RDKKKMVLNVWDFSGGEEFSGSHPHFLTSRALYLVVYNISKGTSQVDALKPWLFNIKAVA
PLSPVILVGTHTDVSEDSQLQNCLSKIRQEILIHQGFPVIRDYYMVSVCEDSDAIARLRK
AIVREVTSFKIQDQPVMGQLVPDSYVELERRILQERARVPPEFPVLRHHELLQLIQESQL
QLEEAELPHAIHFLSEVGVLLHFDDPALELQELYFIDPQWLCSVISQKLTLKSCGYWEHP
KGVVQRSVVEKFLSETKCFPKSHLTQFLKLLEKFQIALPFGEDQLLVPSSLSKHRPVIEL
PHCENSEVIVRLYEMPYFPMDYWSRQISRLLEASSYLLCGREKMVRPNRIYWRRGIYLNW
SQEAYCLVEENPSSCVRITVPASCKGRLLLGQVVDHIDSLLEEWFPGLLNTDMHGSGEAL
LKKWALYSPEDGQEWRKIPLEDIFTDFLGASAENRPCTLPVFQTAPDLLLSDQPAGTTLD
SEELDIDLSLENRLGDGGFGTVYRGVYKNEDVAVKIFNKHASELYIYRLLRQELVVLGRL
RHPSLVSLLAAGSTPQVLVMELALRGSLDSLFQKKNVSFNQKLQHRIALQVADGLRYLHS
AMIIYRDLKPHNILLFNLKTDSDIIAKITDYGIAQYCCSMGVRSSEGTAGFRAPEVARGN
VIYNQQADVFSFGLLLYDLMTRGERISDGMKFPSEFDEIAVQGKLPDPVKHYGCSPWPSF
QVLIKECLQESPQDRPTSAQVFDRLNSGEMLCLMRELVVPGVLSAECFILSSGADSNSSS
HRVWLGGGSRTQKKGSITAVDLNTNTVATQAGSFEVDTSPVLCLVTVQIPNEDSDWLVAG
TQSGSLVVINSRDTSTWHHLQRVTDAVTSLYFHVHPRRTQRKNYLLVGTADGILSIYEDS
VLKQENGQPVKTLSVGNVNTPVMCLGQSVHSLDSRSVWAGCGPKILSFTADYDVCKSIDT
RPNLFSHQQRSLGSEACVYRMVVDKYVYLSKARTTTVEVWDKRSERMVDCIDCAQIIRRD
RGGDGREAELPSEASPSWATVKALLLPNAAMLWIGTRRGHLLLLELPKHQILQVMESHCD
SLRCMASALIQTLNRENVVLVLGRRQTQHKNPNDEESVLTVWNSMLPVEVKDLKKHCEKR
EQIAAKMREQLHQ
NT seq
7602 nt
NT seq
+upstream
nt +downstream
nt
atggttaacaaagaggagctggaagaaaggctgaaaaaacttttggtgaggctgaaaact
ccccaggaagacaggcaactgtgcacgctgattcaaatcatccaggatctgcttttcctg
gcgcacaccgactatgcagctgaactgtttgaagacaaagatgtccacgtgcccctcgtg
ctggttctgtctacccacatcagcagcagaggagtccagcaggttggctggtcattgctg
tgtcagctgattgaaatatgccccactacactggaccagttaaccagacctttggatgaa
gcccaagagtgggaggtagagggagtgcaccagcagatcctcaaggtgttatctcagtac
agcgcagattgtcgagtgaccatggttgcactcagagccttggcactgctgctcagatca
gccaagattcctctgctggtgctgctggaggaggaggaggacgtgtttggccttgtggtg
tacgccatgaaggcgtttcctacaagtgaagaagtgcaactccaaggctgcacagctctg
cagctgcttctggaggaagtcagtgatgaccaccttgtggagtttgtggagaaccaggat
cacgctgtggttctggcagcactcaagaggtttccggacaactcagagatgcagctgcag
gctttaaaagcgctgcttcctctggctcaccctggcagtaatgtggaggtgttgatgtca
gggggcactcggtgctacagcaccatcatcgctgccatggatgctttccctgaggtggag
gagctgcaggagaaagcctgctccctgttcaaaaggtttacttcagagagttacaacgac
atcctggtgaggaatggtgtccacagagtcgcagtcagagcctgccagactttccctaac
aacgccaagctgcaagccgctgctctgtcctgcctggctaacctcactgcaaccatcgtg
cagaacaaagcggtggccgagcagggtctggaggaaggagaggaggaggagaacaggggt
aacgggcaggtggaggacatggagctgagctggatgaaggaatgctttactgcactggag
ctccacgcagatgagccaggtgttcaggaagctgcgtgctgggccattcacagtctgtta
ctgcacggagctgcactgaaccatctagaagaagagcaggatgaaaggactcctgtttat
agacagctgatggcggccatgctgctccacttcgcctctcctaatgtgtttaatgctgct
accagcgccatcgccacactcatcacaaacaacagtaaaatgcgttctttgctgctgtca
agtggccttcatgtgaatttggtggagatgatgaagagacattcagactcagccgaggtt
tccatcagtgcctgcaaactgttaaacctgctcttccagggaaggacagccagtctggat
gagttgaccatggccatgaaccagatcctcagcaccatgaagtttcataactttaatctt
gaggttcagctggaggctctgcaagccagcttggtcttcctttgcccggacaggagttta
agggagcacggcaactcggtcgcagatcccgacatggccgacgtgtctctgaaggtcctg
aaaaaccagtgtgtggtggaaggagctcacatcctctacctggaggctctcaacaggttc
atcagcagctcagccattcaaacgtgtggtttgaaggtgctgtctgctctggctgactgc
tctggtgcggtggatcttctgtgccagcagggggcgatagacacagtgctgcatacacta
caaatgttcccacaggaacgagagatacactactgggggctgaccctactcacctacgtt
gtgtccaagaagaagctctcgaggatgatcgtacctgtactggcctccgttgtggttacc
gctctaattcagtacagagaagactctgagatgctgctaaagtgtttacaggtggcattg
aggatgctagacgcctgttcaggagcagctgctgaactgcagaaagaagactttgacagg
catatcttccagtgccttagagaagagactgaccagagcatcagtccactgcggaagtcg
gtgtgcctggctctgtctaaaatgtggtgcgactcagagctgcactacagcatgctggaa
aaggcctgcatggatggagatacgacaatggccgagtgtctgatcgagctgggagctgac
atcaacaagaagaccaaaaatgagtctctcatttaccaggtctgtgagagaggtggacct
ctggaactggtggaactcttgttaagccgaggctgccacgagcagcacctccgcagggct
ctggccgtgagcgtgaagaggggtgacgggcccacagtcatccagttacttggccgtctg
ggtctggacctcaacaacaatgccctgtgcctgggcggcttcaggctaggccgtctggat
gccgcttggctgagccccctgctgggtgaaagaagcagaacttacagtctacgctacaac
aacactaagggcccgagtctggcaaagtacatccagtttctccagagggccaaaagtgtg
aactgtccccctcggtcagtgactgacccatgtttgacctctggctacatttctgatgag
agcgacgactccagcttcagctttacctctttggaagacggcctgtttttcaacgatgac
atggagagtgatggaagtgattcgctgtctggtgctctttctccaaagtcgtacaacaat
tcatcagaggagctgaggggggaatccttaaggaggaagcagggccgtcgcagacatgcc
agcgcagagagtggtcagactgagagcgagcacactgagcctcttcacagaagatatgga
cggaatagctcgagtcaaaaagtgctggggtctgccgagaactctgctgctctgcccaaa
gagaaagagaggatccacctgctggacctatctgggaatgagctgaactccctgtcctgt
ctcaacgatggctttgtccagcagcagctgtggcatatccaccgtctggacctgagctat
aattgtctgctcgagtttccctctgagctctgcctgagtttgaagaatttgactcgacta
gacctgcaggggaatcagctccagtcgctgccacaggagctgctgtctctgccctcgctg
agcatgctgaacgcctctcgtaactgcgttggcccccagctgacctttgaccctgaagtt
acctgtccaaaactgaagcagctcaacctttcattcaacaaaatcaccacattccctttc
gagctgggccgcaccatgcatacactggaggagctttatatggaaggaaactgtatcact
gagctgtgcacacctctttgtctgcctgagattaagttgcttgatgtgagcaagaacggt
gtggagaatatttctgcagatttcctgagaagctgccccaaactggaaactttgaatgtc
tctatgaacaaactctgttccctgtcccggctgccatcaaagattatgacactaaaactt
gcaaacaatagctttgcatcaattcccgaggctgtacttgaacttccagtgttgcggtca
gtagatatgagaaccaacagcatcgttgttctgcctggcccggcgtcctgggtgtccagc
atcatcagagagctgatgttcagtcagaactgcatacagactctggatctgagtggacct
atccacaaatggaccagactggagaaactccaccttagtgccaataggctcactgagatc
cctccccagattggcttgttggaaggcctgacttccctggatgtgagtcataacactaac
ctgcgctcattcccagatgaaatgggaaaactgagcagactgtgggacctgccactagat
ggccttcagctgcagctggacctcaaactcactggcagcaagacaaaagacatagtcagg
ttccttcagcagcggctgaagaaggcagtgccatactatcggatgaagctcatcgtggtg
gggaacgcaggcagtggaaagaccagcctgatccagcagctgatgaagctaaaacgctcg
cagctgaactcaaaacagacgtcttttggcattgacgtccgcgactggaccgtcagggaa
cgagacaagaagaaaatggtgctgaatgtctgggacttttcaggaggagaggagttcagt
ggttctcaccctcacttcctgacgtccagagctctctacctggtagtttacaacatcagc
aagggaactagtcaagtggacgctctcaaaccttggctcttcaacatcaaagcagtagca
ccgctgtctccagtcattctggtgggcacccacacagatgtgagtgaggactcacagctg
cagaactgcctgagcaaaatcagacaggagatcctgatccaccaaggcttccctgttatc
agggattattacatggtctcagtctgtgaggactcggatgccatcgccagactccgtaag
gccattgtccgggaggtcaccagcttcaagatacaagaccagcccgtgatgggtcagctg
gtgccagacagctacgtggagctggagcgccggattcttcaggaaagagccagggttcct
ccagagttccctgtcctcaggcaccatgagctcctgcagctcatccaagagagtcagctg
cagctggaggaagctgagctccctcatgccatccacttcctcagcgaagtcggggttcta
ttgcacttcgatgatcctgcacttgagcttcaggagctttactttattgacccacagtgg
ctatgcagtgtcatctcacagaaactgaccttaaagagctgtggctactgggagcatcct
aaaggagtggtccagcgctctgtcgtggaaaagtttctgtctgagactaagtgtttccca
aagagtcacctgacacagttcttgaagctgctggagaagtttcagattgctcttccgttt
ggcgaggaccagctgctggtacccagcagtttgtccaaacacagacccgtaatagaactg
cctcactgtgagaactctgaggtgatcgtccgactgtatgagatgccgtacttccccatg
gattactggtctcggcagatcagccgcctgctagaggcatcctcctacttgctttgtgga
agggaaaaaatggtccgacccaaccggatctactggaggagaggaatttacctaaactgg
tcccaggaggcgtactgtctggtggaggaaaacccctccagctgtgtcagaataaccgtg
cctgcatcatgcaaaggccggctgctgctgggtcaggtggtggatcacattgactccctg
ctggaggaatggtttcccggcctgctaaacaccgacatgcacggcagtggagaagctctg
ctgaagaagtgggctctgtacagcccagaggatgggcaggagtggaggaagattcccctg
gaagacatttttacagattttttgggagcgagtgcagaaaatcggccctgcactcttccc
gtctttcaaacagcccctgatctgttattgagtgaccagcctgcaggaacaacactggac
agtgaagaactggatatagatctgtctttagagaaccgactgggggacggtggctttgga
actgtctatcgaggcgtctataagaacgaagatgtagctgtgaagatattcaacaagcat
gcttctgagctttacatctacagactcctcagacaggaattagtcgttttgggtcgcctc
cgtcaccccagcctggtgagcctgctggcagccggctcgactcctcaggtcctggtgatg
gagctggctctgcgcggctctctggattcccttttccaaaagaagaatgttagcttcaac
caaaagctccagcacaggattgccctgcaggtggcagatgggctcaggtaccttcactca
gccatgatcatctatcgggatctgaagcctcacaacatcctcctgttcaacctgaagacc
gactctgacatcatcgccaagatcacagactacggcatcgctcagtactgctgcagcatg
ggagtaagaagctccgaggggacagcaggtttccgagctccagaggttgcccgaggtaat
gtgatttataatcagcaggctgatgtgttctcgttcggcctgctgctctacgacctgatg
acgcgtggcgagcgcatttcagacggcatgaagtttcccagcgagtttgatgaaattgca
gttcagggaaagctgccagatccagttaaacactacggttgctcaccttggcccagcttt
caggttctaataaaggagtgtctgcaggagagcccacaggatcgacccacttctgctcag
gtgtttgacaggttgaattcaggtgaaatgctgtgtcttatgagggagcttgtggttccc
ggggttttgagcgctgagtgcttcattctgagctctggcgccgacagcaattcttccagc
caccgggtctggcttggtggaggcagcaggacccagaagaagggatccatcacagctgtg
gacctgaacaccaacacggtcgctacacaggctggttctttcgaggtcgacaccagtccc
gtcctgtgcctcgtgaccgtccaaatcccaaacgaggacagcgattggctggtggcaggc
acccagtctggctctttagtggtcatcaacagtcgggacacgtcgacttggcaccacctg
cagagggtcaccgacgccgtcacatcactgtacttccatgtacaccctcgacgcactcaa
agaaagaattatttgctggttgggacagcagatggaattcttagcatttatgaggactct
gtgctcaagcaggagaatggccaaccggttaaaacgctcagtgtgggcaacgtcaacact
ccggtcatgtgtttgggccagtcggtgcattcactggacagcaggtctgtgtgggccggc
tgcggacccaagatcctttccttcactgctgactatgatgtctgcaagtccatcgacaca
agaccgaacctcttttcccaccagcagcggtcactggggagcgaggcgtgtgtgtatcgt
atggttgtggataagtacgtgtacctcagcaaagccaggacaacaactgttgaggtttgg
gacaagaggagcgagaggatggtggactgtattgactgtgctcagattattagacgtgac
agaggcggggacggcagagaagctgagctgccctctgaggcgtcgccctcctgggccaca
gtgaaggccctgctcttgccaaacgccgccatgctctggatcggcactagaaggggccac
ctgctgctactggagctccccaaacaccaaattctgcaggtcatggagtcccactgtgat
tctctccgctgcatggcatctgcactcatacaaacacttaacagggagaatgtggtgctg
gttttgggccgaagacaaactcagcacaagaatccaaatgatgaggagtctgtgcttacg
gtgtggaacagcatgctcccggtggaggtcaaagacctgaaaaagcactgcgagaagaga
gagcagatcgcagccaaaatgagagagcagctccaccagtga
DBGET
integrated database retrieval system
