KEGG   Oreochromis niloticus (Nile tilapia): 100697485
Entry
100697485         CDS       T06104                                 
Symbol
plcg2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform X1
  KO
K05859  phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
Organism
onl  Oreochromis niloticus (Nile tilapia)
Pathway
onl00562  Inositol phosphate metabolism
onl01100  Metabolic pathways
onl04012  ErbB signaling pathway
onl04020  Calcium signaling pathway
onl04070  Phosphatidylinositol signaling system
onl04370  VEGF signaling pathway
onl04625  C-type lectin receptor signaling pathway
Module
onl_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:onl00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100697485 (plcg2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    100697485 (plcg2)
   04370 VEGF signaling pathway
    100697485 (plcg2)
   04020 Calcium signaling pathway
    100697485 (plcg2)
   04070 Phosphatidylinositol signaling system
    100697485 (plcg2)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    100697485 (plcg2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:onl04131]
    100697485 (plcg2)
Enzymes [BR:onl01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     100697485 (plcg2)
Membrane trafficking [BR:onl04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    100697485 (plcg2)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    100697485 (plcg2)
SSDB
Motif
Pfam: PI-PLC-X SH2 PI-PLC-Y EF-hand_PLCG2 C2 SH3_1 SH3_9 PH EF-hand_PLCG1 SH2_1 PH_12 SH3_2 PH_14
Other DBs
NCBI-GeneID: 100697485
NCBI-ProteinID: XP_005449270
Ensembl: ENSONIG00000010726
LinkDB
Position
LG7:2880506..2926385
AA seq 1249 aa
MARLGQQGEMTEYRKIVIKRDLEMGVVMTVFRQKAERLTVQVIMETRQVAWTRTADKTDG
VLDLSEIREIRPGRNSKDFERFKDGKDKHDESTCFTIFYGSQFVLSTLSLGADSVDDAQK
WLVGLEMLREETQASPTPVLIESWLRKQMYSVNQTKTNSISLKELKALLPLMNYKAPSSR
TLKEKFQEVGSKKDRLDFEQFHKFYNLLMFEQNEILDEFKKESCAFILGNTDKPDASAVL
LHDFQRFLIYQQQETWANDLNQVREVMTTFIDDTMRKTNDPEFTVSEFLGFLFSKENCIW
DEKFSDISNVDMNNPLSHYWINSSHNTYLTGDQIRSESSTEAYVRCLRLGCRCVELDCWE
GPGEPIIYHGWSRTTKIKFEDVVRAINEHAFVTSEFPVILSIEEHCPIDQQRQMARIFRE
VFGDKLLIDPVEHLAEQLPSPTQMKGKIILKHKKINMEGGFTVKDVRKGQKEGDLEIWDP
VDQRWNKHYCVISDDKLYYAEEYEDEEEDPRKYQDLHCSEPWFHGRMKEGRQMAERLIQE
YCKETGGRDGTFLVRQSDTFVTDYTLSFWRSGRVQHCRIRSVTEGGHTSFYLTPNLHFPS
VYALIQHYRDNPLRCQDFELRLTDAVPKPDSHLQEGWFYSNLSRGQAEDYLMRIPRDGAF
LIRQREGEPDSFAITFRGDGKVKHCRIQKEGNMYLLGTTTEFESLVELVNYFKKKPLYRK
IKLRYPVTPELVDRFSTEKNCASLYDVKTYVEPNEIEPSLPKNTVKALYSYQARRPDELS
FQQGALIHNVSQEADGWCRGDHGGKLQLFFPANYVEPVSSNTEHVTRVQEMEDNPLGELC
QGVVDISKCNIQNLKNGKYGKPHAVTLQDKDEDSLQFDLTAGSLEELFEWYKVAWDIIQR
AANKQYSKEQEMKQQVEVEKKAEVAKEMSEVVVYCQPRSKEKDRFDSYSYKEVRSFVENK
LPGKSRTKDFLQYNRKALSRIYPKGQRVESSNYDPYPMWALGCHMVALNFQTADKYMQLN
NALFSLNGQTGYVLQPEFMRMDSYDPHQEKKEVKYKIVVKVIAARHLPKPGRSIASPFVE
IELCGHTEEKYKTIVYRDNGLNPVWKGSERVVLSVYEPELTFLRFVVNEEDMFSDPNFLA
QATFPVKGLRSGYRSVPLKNGYSEDLELASLLVYISVQQAGKAEEELYSSSSQLKKKQAE
LSEPFLYDTHSNLQRSSLAQPTNNLMRKGSTGENPRSREKKINNSKFYS
NT seq 3750 nt   +upstreamnt  +downstreamnt
atggctcgtttggggcagcagggcgagatgacggagtacaggaagatcgtgatcaagcgg
gatctggagatgggcgtggtcatgacggtgtttcggcagaaggcagagcggctcactgtg
caggtcatcatggagacccgtcaggtggcgtggacacgtaccgcagacaagactgatggc
gtcttggacctgtctgagatccgagagatccgtccgggaaggaactccaaggactttgag
cgcttcaaagatgggaaggacaagcacgatgagagcacctgcttcaccatcttctacggc
tcccagtttgttctcagcaccctcagtctgggagctgattctgtggatgatgcgcagaaa
tggctggtgggacttgaaatgctgagggaggagactcaggcatcaccgaccccagtgctc
atagagagctggctgaggaagcagatgtattctgttaatcagaccaagacaaacagcatc
tccttgaaggaactgaaggcgctgcttcctctgatgaactacaaggccccgagctctcgc
actctgaaagaaaaattccaggaagtgggctcgaagaaggatcgcctggactttgagcag
tttcataaattttacaaccttctcatgtttgagcagaatgagattcttgacgagttcaag
aaagaatcctgcgccttcattctgggtaacacagacaaaccggatgcctcggccgttctc
ctgcacgatttccaacgatttctcatctatcagcaacaggaaacttgggccaatgatctg
aaccaagtcagagaggtgatgacaacctttattgatgacaccatgagaaaaaccaatgac
ccggagttcaccgtcagcgagttcctcggcttcctgttttccaaggagaattgtatttgg
gatgagaagttctcagacatcagcaacgtggacatgaacaaccctttgtcacattactgg
atcaactcctcacacaacacctacctgacaggtgatcagattcgcagcgagtcgtccaca
gaggcttatgtccgctgtctgcgtctgggatgccgctgcgtcgaattggactgctgggag
ggccccggggagccaatcatttaccacggctggagcaggacgacgaagatcaagtttgag
gatgtggtcagagcgataaacgagcacgcttttgtcacctcggagttcccggtgattctg
tccatagaggagcactgccctatagatcagcagcgtcagatggctcgtattttcagagaa
gtatttggagacaaactgctgatcgatcccgtggagcacctggccgagcagctgccttca
cccacgcagatgaagggcaagatcatactcaagcacaagaagatcaacatggagggagga
tttaccgtcaaggatgttagaaagggacagaaagaaggagacctggagatctgggaccct
gtggatcagcgctggaacaagcactactgtgtgatctctgacgacaagctgtactacgca
gaagagtacgaggatgaggaagaggatcccaggaagtatcaggaccttcactgctcggag
ccgtggttccacggtcgcatgaaggaaggcaggcagatggccgagcggctgatccaagag
tactgtaaagagaccggcggacgagacggcaccttcttggtccgacagagcgataccttc
gttacagactatacgctctccttctggcgaagcgggagggtgcagcactgtcgcattcgc
tccgtcacagagggcggacacacctccttctacctgacgccaaacctgcactttcccagc
gtgtacgccctgatccagcactacagagacaacccgctgcgctgccaggactttgagctg
cgcctcaccgatgccgtaccaaaacctgactcacatctgcaagaagggtggttctacagt
aacctgagcagaggtcaggcagaggattacctaatgaggattcccagagatggagctttt
ctcatccggcagagagaaggagaaccagactcctttgccatcacattcagaggtgacggt
aaggtgaaacactgccgcatccagaaggagggcaacatgtatctgctgggcaccactacg
gagttcgagagcctcgtggagctggtcaactactttaagaagaagccgctgtatcgcaag
attaagctacgctacccggtcacgcccgagctggtcgaccgcttcagcacagagaagaac
tgtgcctctctatatgacgtgaagacgtatgtggagcccaatgagatcgagccctcgctg
cctaaaaatactgtgaaggcattatacagctaccaggcgaggaggccagatgagctgagc
tttcaacaaggagctttgatacacaacgtgtcccaagaggctgatggatggtgcagagga
gaccacggtggaaagttacagttattctttcctgctaactacgtggagccagtgtccagc
aacaccgagcatgtcaccagagtgcaggaaatggaagataacccactaggtgaactatgt
cagggcgtcgtggacatctccaaatgcaacattcaaaacttgaagaatggtaaatacggg
aagccccatgcagtgaccttgcaggacaaggatgaagacagtctgcagtttgacttgact
gcaggttctctggaagagctgtttgaatggtacaaggtggcatgggacattattcagaga
gcagcgaacaagcagtacagcaaggagcaagagatgaaacaacaggtggaagtggagaag
aaggcagaggttgccaaggagatgtcggaggtggtggtctactgtcagccacgcagcaaa
gagaaggaccgctttgacagttacagctacaaggaggtccgctccttcgtggagaacaag
cttccagggaagagccgcaccaaagacttcctgcagtacaaccgcaaagctctgagtcgt
atctacccaaaaggccagcgcgtcgagtcctcaaactacgacccttacccgatgtgggcc
ctcggctgtcacatggtggctctcaacttccaaacagcagataaatacatgcagctgaac
aacgccctcttcagtctgaacggacaaacgggctacgtgctgcagccggagttcatgcgc
atggatagctacgaccctcatcaggagaagaaggaagtcaaatacaaaattgtggtcaag
gtgattgctgccagacaccttccgaagccaggccgcagcatcgccagtccattcgtggag
atcgagctgtgcgggcacacagaggagaagtacaagaccatcgtctatcgtgacaatggt
ctgaacccagtgtggaaaggctcagagcgcgtagtcttgagtgtgtatgagcctgaactc
accttcctgcgcttcgtcgtcaacgaggaggacatgttctcagaccccaactttctggct
caggccacgtttcctgtgaaaggcctccgctcaggttaccgctctgtccctctaaagaac
ggctacagtgaagacttggagctagcttctcttctggtctacatcagtgtgcagcaggcc
gggaaagcggaggaggagctgtactcgtcttccagccagctgaagaagaagcaggcagag
ctgagtgaacccttcctgtacgacacacacagcaaccttcagcgatcctccctggcccag
cccactaacaacctcatgaggaagggcagcactggtgaaaatccaaggtcaagggaaaag
aagataaacaacagtaaattttactcctga

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