Oreochromis niloticus (Nile tilapia): 100700801 Help Entry 100700801         CDS       T06104                                  Name (RefSeq) obscurin   KO K17531   obscurin-RhoGEF [EC:2.7.11.1] Organism onl  Oreochromis niloticus (Nile tilapia) Pathway onl04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:onl00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     100700801  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:onl01001]     100700801   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:onl04131]     100700801 Enzymes [BR:onl01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      100700801 Protein kinases [BR:onl01001]  Serine/threonine kinases: CAMK group   Trio family [OT]    100700801 Membrane trafficking [BR:onl04131]  Others   Rho GTPase associated proteins    Rho guanine nucleotide exchange factors (GEFs)     100700801 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  I-set Ig_3 ig Ig_2 V-set Pkinase PK_Tyr_Ser-Thr Ig_5 Ig_4 Izumo-Ig SOS1_NGEF_PH Ig_CD22 C1-set RhoGEF C2-set_2 Sp38 ABC1 fn3 Kdo PH Kinase-like IQ_SEC7_PH IQ APH RHG20_PH Motif Other DBs NCBI-GeneID:  100700801 NCBI-ProteinID:  XP_019207443 LinkDB All DBs Position LG23:complement(45029240..45077400) Genome browser AA seq 6090 aa AA seqDB search MGDNKPGGIVAAAKNRLQVVKGLDDAEVSECESCSFEVTLNLAYIEGMWMRDGTQLKSKP NCRISTHGKKHSLLLNRVALGDAGLFSFQANGIQTSGRLTVRARDIHIVKELEDVDTIER QPVTFVCEVNQMDVDGRWYRDDCRIRPGDSIRIRHQGKTHTLSFKSVRPEHAGEIRFTAE RVSSCATLTVQELPVQIVRPLRVKIAMYRHRGLLECHVSRPNAEVRWYKNRKELLPSKKY HLISQDIYRQLAINDVCSSDEDTYTCDAQDDKTSCQLLVEEQAITIVRGMKSVEVMEPEP ARFQVETNLKSGRPPKWTLNGEVLEPCAAVNIDREATLHSLCFTSTESSMSGPVVFVAGK SRSTAQLTVKERPLQVVHHLDDVEAKESSSVTLSCEFAPSPRVVRWFKGRTALKSSNKYS MNREGKRAELTIHGLTAMDAGQYRCLAGGSQSSAHVKVEVRKLKLVKHLEPVEIEENGVA TFSCELNYVVANVEWLLNNVRLYSNAINKIHHMGTMHRLTIKKLRPQESRVTFKAGLLTE TTTLKVKECPAVFLRPLEDAVGEEQGELCLQCEISKETASPAWKKDGVVLTADDKHELLQ FGKSMALVIHSLSKDDAGQYTCDLGTSQTKAKVTVHDLHITIVQRLKTTAVLEGDTCTFE CLLSHDLDDKPSWTINGQLVVTNSRIQLTNSGRMYTMTVRDALLTDAGDVVFTIKDLTCR TMLFVQEKPVHIFRDLLNVKAVPGEDAELTCEITKPEVTIRWLKNGRLIKESPKYEMSVE KHLARLVIKSTTIRDSGEYCCEAEGVASRAKLEIRELQHTFARELKDTRAEEKGKVTLEC ETRQPAKRVTWLKGLIELRPGRKYVIRQKGVVLSLTITSLEKSDTDIYICDVGTMQSRAQ LTVQGQKVVILDELEDVECLEGDTVTFRCRISPSDYAGAKWYLDETLLYTNELNEIQVLS GGFHTLTFKQLARKDTGTISFAAGDKRSYASLLVRERRPTICKSLEDCEAIEGGGLILSC VTSKPCHILWYKDGCLMWNSSRYFTSRLGCEARLTIREVCQTDAGVYECSAGSVTTRAAV TVKAIPAEFIHHLKHVEAKEGEAVTLTCEYSLPGVQVHWKKGFESIRPGDKYVMRQRKTI NSLTIKALKPEDAGQYTCQCRDHHTTASLKVHAVPITFIQQLKNMQAEEGSSVILRCEIS KPGIPVEWRKEDEVLKNSVKYQIRKRETTLELLIWKPVPEDGGVYSCVCADQMTSATVKI TALPVTFKQKLRNVLIEEGNTATLRCELSKPGHTVEWRKGGDELIRNGEKYHIRQRDMLI ELRIFDVTPEDSNIYTCICGNVETTATLTVNALPIVFKQKLKNVQVEEGHNITLCCEISK PGVSVEWRLGGDLLEHGDKYQIKQRDSVLELTIRDAVPEDSGVYTCVCREQRTKSTVKVI AIPATFKVSLKSQVAEEGTSMTLQCELSKKGVPIQWQKQGQLLSEEGSRGKYRIELEGKT AKLTVLNIQPEDAGKYSCITGDEKTTAEVKVKPLPVTFKREIRNLVVKEGDSGVFCCELS KPGAAISWRKGRVILKPGEKYEMKQDGCVTRLIINNVEDSDAGKYTCKTKDSQSTAELTV VESPKRRRQRESPPSFKILLANQEVTEGSSVVLRCELTKPASAVEWRRGGELLKNGDKYQ MRKKDLQVEMKIADLCVEDSGDYTCICGEQRTTAEIRVNERPIKFLQDLKNIQVQEGGVV TLCCELSQPGVPVQWTKGDTVLSNGDKYQIKQSGCIHELHIRKSLPEDSGTYSCICDEIK SMATTIVTAIPVTFKQKLKNQEAVEEGCVTLRCELSKAGVPVEWRKEAHLVKEGEKIQIK QEGRVVEMLIRNVTLADSGEYSCSVGTVVTSADIKVRALPVTFTKEVENLEVREGDGGVF CCELSKPGAPVDWRKGRVILKPGYKYEMKQEGRVTKLIINNVEESDAGKYTCKTKDSQST AELTVKAPPVTFKTKLKNQQVEEENSVTLSCELSKPGLAVEWRKGEELLRNNFKYQIKNR NNVMELTVKNAQLEDSGLYSCFHGDVKTTANVTITPIPLTFRMGLKNQEAPEGGNVSLRC ELSRAGVPVQWWKGEDQLYHGGRYQMILKGRIAEMTIRNIQPEDVGEYSCAFGEQKTTAE VNVRAAASVFFEKELESQTVMEGKSVLFSCEVSSPNVPVTWKKGNTVVEEGGRYIVTKKG PSHTLEIKKLHLEDAGEFCCITRGKKTTAKLIVRAPSSSAERVRIVTELQDKAVTAGEDA VFVCELSHADVSEGVWWLGNSPLQKNEMNQMTCHGRQHRLVLTMTTPEETGTVAFVVGEE RTSARLLVVPKPKVLLEEKPKDTVVMEGETATLSCTTSDLTTLVTWKRNHIPLRNGDKYE MRKEGKVNLLLIRDVDPLDTGVYSCDTGDMQSTAKLTVTELPPFFQEELQSVEAEEGASA TLYCELSKLGVPVQWKKNSLPLRASRKYEMRQDGCFLQLHIKELKLEDSGSYSCQAGGAE TSATVSVKELPPFFKKELRSVEADEGGTASLYCELSRPGVSVQWKKNRLPLRASRKYEIR QEGCILQLHIKELKPEDSGSYTCQAGSAETSTNVSVKELAPFFQKELQNMKAEEGSTASL CCELSKPGVSVQWKKNKLPLRASRKYEMKQDGCLVQLHIKELKPEDSGSYTCQAGSTETT AAVTVRELPLVFREELQSIAAEEGGTALLSCELSKPGISGEWRRNKLPLRASRKYEMKQD GCLLQLHVKELKPEDSGSYTCRAGTAETTAKVSVTERPPVFKQDLKDVAAEEGGTAFLCC EVSKPGLSVQWKKNKLPLRANRKYEMKQDGCLLQLHIKELKPEDSGSYSCRAGAAETAAT LTVQELPPFFKRELQNIEGEEESTAALHCEVSKPGVSVQWKKNKTPLRANRKYEMKQDGC LLQLHIKDLKPEDSGSYTCKAGGAETSGTVTVKELPPFFKRGLQSMEVEEGCTASLSCEL SKPGVMVQWKKNGLLVRPNAKYEMKQEGCFIQLLIKELTVEDSGSYTCQAGKAETSAAVT VKELTLFFNKELESIAAEAGGAASLYCELSKPSVSIQWKKNKLPLRASRKYEMKQDGCFL QLIISGLKPEDSGNYSCQAGSIETTAMVQVKGLQPTPAEAEPPTIMPQVKETVSKTTPTQ ETQRPGVSEGKAAPPEPKKRARKASIANSEKDTELVFDLGPSALKDDDKVQKDIQSARAV EKGTDGAQNAAHEQINKVKDREVNKKADKPVRLLETIDYRVDGKVGEPAKHLEKETDALP EMKQTRRHTEELAPADHEETQSDRALDKTCFEQRKQKEKKRGTEKSSEQLEIPLAKSEVD EKRKHPAAEVGMISQDEKSPVKPLEGLISKESMKDQNMKSLENEGELDKTEGEPLKPPTR SKGKLTDGKQPIKYLLKDSEEILPTMLKTTQIDSEEDGKQRDRLNKQVSKESERGTKPEQ VFDKEPTEQPERPVENEAPFTHPKPPVRTKSKVKGVEKQVSRDTETDREEQEPTSGVVKV QDQPIKQLLKPLIKQAKEKPAFERNQPVTATEKTEQPAKPPLKQPVKPMRKEPKMDQDVS LAVEPTRREEEQQTKVAEDIPLLYISEDETFSEALTEIPAEILLQTTEPLKESPPEIEIS TEDEPQMQEAAVKIQAAFKGFKTRKDMRPVFKEVFKNRTAALHGMLTLMCVVEGKPSAVR WLRNGQQISNDQRCRITTTDDGECTLVIKNLLNSDSGIYTCEVVNKFGVTSYNGNITVVQ TPQPAPVAQRPVHPPLAAITPLQLAPTKPEAPPKDQNENLPQSQAQVPTSAENYAESMNV SLWEAYTLTEHAPQQTLQERRRSSVMAASSMSSPSDYDTAPDMMEPVEISTITPREEPKP TEQAAPKDDNEEITQPPTMLLKIKGAHDGKMRTPSPKHRAHTPLDSTVSGSESEGEEDRR ETFEIYVARAHCCPNSGSKESFILKEGQFVEVLDSVHPDRWLVRTKPTKTNPGRQGWLCP AYLEKKRKETFPQLRARQEDLDGIGCTGEEYRRGLSQLIQGLIDGEEEFVREMKMFISQQ LNFLDSSYHVPVNVLNQKEIIFRNIKDIVLLHERCVLPGLRECATDDDVAMHLIKHREDF EKYIHYMVGQAQAEACIADKTVQQFFKELTEAGKLDGAVMDVLTFLQQPVERIQTYKALL KELIKNKAKSGQSCYLLEDAFSLVSCLPWRSDNLHKVSLIENYPAPLIALGEPVRQGSFT VLEETPEIKTPSRGHQRQVFLFKECIVLCKLKKDTSMNRDTYSFKNKMKLNDVEIKETVG GDERSWGLWHEHRGSIRRYTLQGSSTLVKLSWLKDLKELQQRSSLPTNSPPVFELLLSDC TSKMGQTIKLTCKVSGSPKPEISWLKDGLPLEDDPRHIITADRSGCCSLIVDSLTAEDSG EYACYATSFMGSAGTLAKVVVQTPPRFVSRLESACLIEGEDIQFSCSTFTTPLPRIRWLK DGKELTEQQKYLIMNDARSGILSLTVVGATEADIGQYECELWNELGGVKCKAGLCPAYVP PTDRENDQSQDLPPKDPDSEGWSAAFVKKWLQADFNPTSKAKMLFPPESPEHAEGGAEVT LYAPTSADQAPQQPMSYHEEEEEIYISEQIQEIADAPPSIQIPIEDLFVEPGHPSTFIAI ITGRPAPKIKWYKDEEELAANENVKMGQHGARCSLTIVCTEGEDSGMYTCFAHNDSGYAS CQAELTVEEGPLEFQEREVELGKRRKLFSVYDVHDEIGRGTFGVVKRIVHRRTGEVFAAK FLPLRSSTRTRAFQERDLLSRLAHPRVACLLDFFCTRRTLVLITEICCSHGLLDHLFLKG SVSEKEIQSFIQQILEGVGHIHSMNILHLDIKPDNILMVYPPRDEIKICDFGFCQEIDTS RHQYSMFGTPEFVAPEIVHQEPVTVATDIWAVGVVAFLCLVCRCPFVGETDRATLLTVGE GTLNWAAPDIMYRSPEAKNFLHMLLQPDPEKRPSAFECLGHDWIQDEHAGEDTDEINTRS LKAFISKRKWQRSLTCIGSVLTLRPIPELLDAPLRETAVTVPREPQEHSSTSPSSGSSSE YDEADSWDFFQHCSQTEEEEETEEDYDPLMERAQIPDPFPSFHRDGEEEGDLTLGEEEDG EIVGRRTVLERSISRQSVASSEVSCQRTPQRERRFSKDSSPSLYLSDGDEGSGSDGGRIP RGSVIRSTFYSNSHQLSPLSARHMTLRDKFQAKKQERGRKPLRRSFSGRLNEPLIEYVED ETETSRGQRRASIQTAMQKSCSFDSGVGFAHANAPPHRRSRSLDEYSRRSPTSPKRANAG EEEGSQSLKEDFTDDEVAGTNLLAIPNSQRATRRGSVTPVQVIQTFRGSSVPSRLDQVQT EGDNFAGSQGSLAESFILEHGGSESSSRLGSNEELSHGRLRGRYRSGDGDGYDDQGERLI APSPRSFQEVKPRSSFPRAPPRNRTRSNPNLSTNSRGQLGTPLMPSPSPSLSSLQAPERP PRARDKKEGHSLQRHASAPALEARPPTGRSPKLGLLNIFRRQSWTGHSYSHLEDTELGPT LGEIMKPDTPTMSLRKRMRASASSLTKLFSRSSSKEDVSKGGPIVKGSAPTPPERKRSSS LESPKKRSSKLLPSFKIPAFKKKDLPVRPSKAEVLQLDGGGVLLAWRPVHSSDPVTYCVQ YCTDGGEWTVLSEDVTDSCYVAKDLPRGASYVFRVGCVTKMGAGPFSDASAPVVMATHPE EIHIPLIQTESLGSKVIGSEQAAHKNYNFLPEINRGRFSVVALCRNAETSQVFAAKITPY QAEQRQLVLREYQLLRRLHHPHLVQLHCAFITSCYLVLVEELCPGKELLYSLAARDLYAE TQVAEVLVQILSAVDYLHSRRVIHLDLKSDNMLVDDCNHLKIVDFGSAQSFTPGQPLNIE HIQGFSDSRDSCSKAPEILEGQGVGPETDIWAVGVLSFIMLSADSPFHAEHSWDQDRNIR KGKIQFGRCYPGLSEGALNFMKSSLNNKSWGRPTAAECLQNPWLRAHRAPHKARHSKVCF STDKLKAYLKQKEEKRDQVRTKLQGPFFFQ NT seq 18273 nt NT seq  +upstreamnt  +downstreamnt atgggagacaataagcctggaggaatagtagcagctgcaaagaaccgtctgcaggtggtg aagggattggacgatgcagaggtctcagagtgtgagagctgctcctttgaggttactctt aacctagcctacatagagggcatgtggatgagggatgggacgcagctcaaatctaaaccc aactgtcgcatcagcacacacgggaagaaacactccctcttactgaacagggtggctttg ggagatgccggtttgttctcctttcaagctaatggcattcagacctcaggccgactcact gtcagagctagggacattcacatcgtgaaggagctggaagatgtcgacacaatcgagcgt caacctgtaaccttcgtgtgcgaggtcaaccagatggatgtggatggtcggtggtacaga gatgactgccggatccgtcctggagacagcatcaggatcagacaccaaggtaaaactcat actctgtccttcaagtcagtcagaccagaacatgcaggagagatcaggttcacggcagag cgggtctcatcctgtgcaactctcacggtacaagagcttccagtccaaatagtgcgtcct ctgagagtaaaaattgccatgtatcgccaccgaggtctgctggagtgccacgtgtcacgg cctaatgctgaggtcaggtggtacaagaacaggaaggagctacttcccagcaagaagtat catctaatcagccaagatatctacaggcagcttgctatcaatgatgtctgctcgtcagat gaagacacctacacatgtgatgcacaggatgataaaacctcctgccagcttctggtagag gagcaggctatcaccatagtgcgggggatgaaatcggtggaggtgatggagccagagcct gcacgattccaggtagagaccaacttgaaatcagggaggccaccaaagtggacgctgaac ggtgaggtcctggagccatgcgcggcagtgaacattgacagggaggccaccctccacagc ctgtgcttcacctccacagaaagctccatgtcaggcccggtggtctttgtagctggaaag agtcgttccaccgctcagcttacggttaaagagcggcctcttcaggtggtccaccacttg gatgacgtggaggcaaaagagagcagctctgtgactctgagctgtgagtttgccccatct cccagggtggtgcgctggtttaagggccgcacagctctgaaatcctctaacaagtacagc atgaatagggaggggaaacgagcagagctgaccatccacggcctgacggcgatggatgcg ggacagtaccgctgtctggctggagggtcacagagctcggcacatgttaaagtagaagtg cggaaactgaagttggtcaaacaccttgaaccggtggaaattgaggagaatggcgtcgcc actttctcatgcgaactcaactacgtggtggccaatgtggaatggctcctcaacaacgtc cggctctattccaacgccatcaacaagatccaccacatgggcaccatgcacaggctcaca atcaaaaagcttcggccacaggagagcagggttaccttcaaagcgggccttctcactgag acaaccaccttaaaggtcaaagaatgcccagcagtgttcctgaggcctctggaggatgca gttggagaggagcaaggggagctttgtcttcagtgtgaaatttccaaagagacggcgagc cctgcttggaagaaggacggtgtagttctgacagctgatgacaaacacgagctgctccag tttgggaagtccatggctttggtcatccattcactgagtaaggatgatgcaggacagtac acgtgtgatctcggcacaagtcagaccaaagctaaagtcacagtacatgacttacacatt acaatcgtccagcgtttgaagacgaccgctgtcctcgagggagacacctgcacttttgag tgtcttctctcccatgatcttgacgataaaccttcttggacaattaacggccagctcgtg gttaccaacagccgcattcagctcaccaacagtggccgcatgtatacgatgacagttaga gatgcgttacttactgacgctggagatgtggtcttcacaattaaagatctaacctgtagg accatgctttttgttcaagagaagccagtgcacatcttcagggacttgttgaacgtcaag gccgtgcctggtgaggatgcagagctgacctgtgaaatcaccaaacctgaagtcaccatc cgctggctgaaaaatgggcgtctgatcaaggagagccccaagtatgagatgagcgtggag aaacatctggcacgattggtgatcaaaagcaccactatccgagactctggagagtactgc tgtgaggccgaaggcgtggcctcccgtgccaagcttgagatcagagagttacagcacacg tttgccagggagctgaaagacactcgagcagaagaaaaaggaaaggtgacactcgagtgc gagacgaggcagccagccaaacgcgtgacctggctgaagggcttgattgagctgcggcct ggaaggaagtatgtcatcaggcagaagggcgtggtgctgtccctcaccatcacctcactg gagaaatcggacacagatatttatatatgtgatgttggcaccatgcaaagccgggcacag ctgactgtgcaaggtcagaaggtggtgatactggatgaactggaagacgttgagtgtctg gagggggacacagtcacattcaggtgtcgtatctctcccagtgactacgctggggccaag tggtatttggatgagactttgctttataccaacgagctcaatgagatccaggtgctttca ggaggcttccacacccttacgtttaaacagctggcccgtaaagacactggcactatttcc ttcgcagcaggggacaaaagatcttacgcctcgctgttggtccgagaaaggcgtcccacc atttgtaagtcacttgaggactgtgaggccatcgaaggaggtggcttgattttgtcctgt gtgacctccaagccgtgtcacatcctgtggtacaaagatggctgtctcatgtggaactcc tcaagatactttaccagtcgtttggggtgcgaagctcggctgaccatccgagaagtttgc caaacagatgcaggagtgtacgagtgcagtgctggctctgttacaactagggccgcggtc actgtcaaagccatcccagcagagttcatccaccatttgaagcatgtggaggccaaagaa ggagaagctgtcaccctgacctgtgagtactctctgcctggggtccaggtccactggaag aaaggttttgagagcatcaggccaggagacaagtacgtgatgagacagaggaaaacgatc aactctctgaccatcaaagccctgaaacccgaggacgctggacagtatacatgccagtgc agagaccaccacactacagcaagtctcaaagtacacgctgttccgatcacattcatacaa caactcaagaatatgcaagcagaagagggcagcagtgtcatattgcgctgtgaaatttcc aaacctggaataccggtagagtggaggaaagaggatgaggtgctgaagaatagtgtgaag taccagataaggaaaagggagaccacactggagctcctcatatggaaacctgtgcccgag gacggtggggtctacagctgtgtgtgtgctgatcagatgacatctgccactgtcaagatt actgctctcccagtcaccttcaagcagaagctgaggaacgtgttgatagaggagggcaac actgccacgttacgctgtgagctctccaaacctggtcacacagtggagtggaggaaaggc ggggatgaactgataagaaatggagagaaatatcacatacgacagagagacatgctcatt gaactgaggatctttgacgtgacccccgaggacagcaacatctacacatgcatctgtgga aacgtggagaccaccgctactctgactgttaatgctcttcccatcgtcttcaaacaaaag ctaaaaaatgtacaagtcgaggaaggacacaacatcacgctgtgttgtgagatctctaaa cctggtgtctcagtggaatggaggcttggaggagatctgcttgagcacggagacaagtac cagataaagcagagggactcggtcctggagctgaccatcagagatgctgtaccagaggac agcggtgtctacacatgtgtctgccgagagcagaggacaaagtctactgttaaagttatt gcgatccccgcgacatttaaggtgagcctgaagagtcaggtggccgaagaagggaccagc atgacgttacagtgtgagctgtcaaagaagggagtcccgattcagtggcagaagcagggt cagctgctctctgaggagggatctcggggaaagtatcgcatagagctcgaaggaaagacg gctaaactgaccgttttaaacatccaaccagaagacgcaggaaaatacagctgcatcaca ggagatgagaaaaccaccgctgaagtcaaagtgaaaccacttcctgtgacatttaaacgg gagatccggaacctggtggtaaaggaaggcgacagcggcgttttctgctgtgagctctcc aaacctggagctgcaatcagctggaggaaaggcagagtcattctgaaacctggagagaaa tacgagatgaaacaggacggatgcgtcaccaggctgatcatcaacaacgtggaggacagc gatgccggcaaatacacctgcaagactaaagacagccaatccactgctgagctcacagtc gtagagtcacccaagcgcagacgccaaagagagtcaccgcctagtttcaagatactgcta gccaatcaggaggtgacggagggcagcagcgtggttctacgctgtgagctcaccaaacct gcgtccgcggtggagtggaggagaggaggagagctgctgaagaatggagacaagtaccag atgaggaaaaaagacctgcaggtggagatgaagatcgcagacctctgtgtggaggacagt ggagattatacttgtatatgtggagaacagaggacaacagctgagatcagagtgaatgag cggcctatcaaatttcttcaagacttgaagaatattcaggtgcaggagggcggtgttgtt acactgtgctgtgagctgtcccagcctggggtccccgtgcagtggacaaagggagacact gtcctttccaatggagacaaataccagatcaagcagagcggctgcatccacgagctccac atcaggaaaagcctccctgaggacagcgggacctacagctgcatttgtgatgagataaaa tccatggcaacaacaatcgttactgcaataccagtgacctttaagcagaaactgaagaac caggaagctgtggaggagggctgcgtgaccttacgctgtgagctttcaaaagccggagtc cccgtggagtggaggaaagaggctcacctggtgaaagagggagaaaaaattcaaataaag caagaaggccgagtggtggagatgttaatcagaaatgtaactctggcagactctggcgag tacagctgttctgttgggaccgttgtgacatcagctgacatcaaagtaagagcacttcct gttacatttacaaaggaggttgagaatttggaggtgagggagggggacggtggagttttc tgctgtgagctctccaaacctggagctccggtggactggagaaaaggcagagtgatcctg aagcctggatacaaatatgagatgaaacaggagggacgcgtcaccaagctgatcatcaac aacgtggaggagagcgatgctggcaaatacacctgcaagactaaagacagccaatccact gctgagctcacagttaaagcgccgccagtcacattcaaaactaagctaaagaaccagcag gtggaggaggagaacagcgtgaccctgagctgcgagctgtccaagcctggccttgctgtg gagtggcggaaaggagaagagctgctgaggaataatttcaagtaccagattaaaaaccga aacaacgtcatggagctgacggtcaaaaatgcacaactggaggacagtggcctctacagc tgtttccatggagatgtcaagactacagccaatgtcacaatcacacctataccgcttacg ttcagaatgggtctgaagaaccaggaggcccctgaaggaggcaacgtgtccctgcgctgt gaactatccagggccggggtgcccgtacagtggtggaagggggaggaccagctttatcat ggaggaagatatcagatgatactgaaggggaggatagctgagatgaccatcaggaacatc cagccagaggatgtcggcgagtacagctgcgccttcggggagcagaagacgacagctgaa gtcaacgtgagagcggcagcatctgtgttctttgaaaaggaacttgagagccaaactgtg atggaggggaagtctgtgctgttctcctgtgaagtctccagtcctaacgtgcccgtaacg tggaagaagggcaacactgtggtggaagaaggaggacgttatatcgtaacaaagaaaggc cccagtcacactctggagatcaagaaattgcatctggaggatgctggggagttctgctgt atcaccaggggcaagaagaccactgccaagttgattgtcagggctccttcttcctccgca gagcgcgttcggatcgttacagagcttcaagacaaagcggtgacagcgggagaggacgcg gtgtttgtgtgcgagctgagccacgcagacgtgagcgagggcgtctggtggcttgggaac agccctctgcagaagaacgagatgaatcagatgacgtgtcacggccgacagcaccgactg gtgctcaccatgacaacgcctgaggagacgggcacggttgcttttgtggtcggggaggag aggacctctgcacgcctgctggttgttccgaagcctaaagttttattggaggagaagccc aaagacacggtggtcatggagggcgagacggctactttgagttgcaccacctctgacctc accaccttggttacctggaaacgcaaccacattcctcttcgaaatggtgataaatacgag atgcgcaaggagggaaaagtcaacctgctgctcatccgtgatgtcgaccccctggatact ggtgtatactcctgtgatacaggagacatgcagagcactgccaaacttaccgtcactgag cttcctccgttcttccaggaggagcttcagagtgtggaagctgaagaaggagcttcggcc accctgtactgcgagttgtccaaacttggagtaccagttcagtggaagaaaaacagcttg cccctaagagcgagcaggaagtatgagatgcgacaggacggttgcttcctccagcttcac atcaaggagctcaaacttgaagacagtggcagctactcgtgccaagcagggggtgcagag accagtgcaactgtgtctgtgaaagaacttcctccattcttcaagaaagaattaagaagt gtggaggctgacgagggaggtacagcctccttgtactgcgagttgtccagacctggagtg tcagtgcagtggaagaagaacagactacctctgagagccagcaggaagtatgagatcagg caagagggctgcatcttacagcttcacatcaaagagctcaagcctgaagacagtggcagc tacacatgccaagcaggaagtgcagaaaccagcacaaatgtgtcagtgaaagagcttgca ccatttttccaaaaagagctgcagaatatgaaggcagaggagggaagtacggcatcactg tgctgtgagctgtctaagcctggggtgtcagtgcagtggaagaagaacaagctgcctctg agagccagcaggaagtatgagatgaagcaggacggctgcttagtccagcttcatatcaaa gagctcaaacccgaggacagcggcagctacacgtgtcaagcagggagcacagagaccact gcagctgtaacagtgagagagcttccacttgttttcagagaagaattacaaagtatagct gcagaggaaggaggtacagccttattgtcctgtgagctgtccaagcctggcatatcaggg gagtggaggaggaacaagctgcctctgagagccagcaggaagtatgagatgaagcaggac ggctgcctcctccagcttcatgtcaaagagctcaaacccgaggacagcggcagctacacg tgtcgagcagggacggctgaaactactgcaaaagtgtccgtgacagagcgcccacctgtt ttcaaacaagatttgaaagatgtggctgctgaggaaggaggcacagccttcctgtgctgt gaagtgtctaaacctggattatcagtgcagtggaagaagaacaagctgccactgagagca aacaggaagtatgagatgaagcaggacggctgcctcctccagcttcatatcaaagagctc aaacccgaggacagcggcagctactcgtgtcgagcaggagctgcagagacagctgcaact ctgacagtgcaagagctgcctcctttcttcaagagagaattacaaaatatagaaggcgag gaggaaagcacagcagccctgcactgtgaagtgtctaaacctggggtgtcagtgcagtgg aagaaaaacaaaacaccattaagagccaacaggaagtatgagatgaagcaggacggctgc ctcctccagctccacatcaaagatctcaaacccgaggacagcggcagctacacctgtaaa gctggaggtgcagaaaccagtgggactgtgacagtaaaggagctccctccattcttcaag cgaggtttacagagcatggaagttgaagaaggatgcacggcttccctttcctgtgaactg tctaaacctggagttatggtgcagtggaagaagaacgggctgctggtgagaccgaatgca aagtatgaaatgaagcaggagggctgcttcatccagctgctgattaaggagctcacagtg gaagacagcggcagctacacgtgccaagcaggcaaagcagagaccagcgcagctgtaaca gtgaaagagctcactctattcttcaataaagaattagaaagtatagcggctgaagcagga ggtgcagcttccctgtattgtgagctgtctaagcccagcgtatcaatacagtggaaaaag aacaagctcccactgagggccagcaggaagtatgagatgaagcaagatggctgcttcctg cagctgatcatcagtgggctcaaacctgaagacagtggtaactactcttgtcaggcagga agcatagagaccactgcaatggtgcaagtaaaaggactacaaccgactccagcagaggca gaacctccaacaatcatgccgcaggtaaaagaaaccgtttccaaaacaactcctactcag gagacgcagagaccgggagtctcagagggtaaagcagctcctcctgagcctaaaaagagg gcaagaaaagcatcaattgcaaattcagaaaaagacacagagcttgtttttgacctcgga ccgtctgcgctgaaggatgatgataaagtccaaaaggacattcagtctgcaagagccgta gaaaaaggcactgatggtgcacagaacgcagcacatgaacagattaataaagtgaaggac agggaagtgaacaagaaagctgataaacctgtgagactactggagactatagactatagg gttgacgggaaggttggggagccagctaagcatttggaaaaagaaactgatgctttaccg gagatgaaacaaacaagaagacatactgaagaattagctccagctgaccacgaagaaact caatcagacagggctttggataaaacatgttttgaacaaaggaaacaaaaagaaaagaaa cgtggaactgaaaagagctcagaacaactagaaatacctttggcaaaaagtgaagttgat gagaagaggaaacatccagctgcagaagtaggaatgattagccaggatgaaaagtctcct gtgaaaccactagaagggttgattagcaaagaatcaatgaaagatcaaaatatgaaatct ttagaaaatgaaggtgaactagacaagacagaaggagagcctttgaaaccaccaacaaga tctaaaggaaaactgacagatggaaagcaaccaatcaagtatttactgaaggatagtgag gagatccttcctacaatgctaaagactacacagatcgattctgaagaagacggcaaacag agagatcgtctgaataaacaagtgtccaaagagtcagagagaggaacaaagccagaacaa gtgtttgacaaagagccaactgaacaaccagaacggccggtagaaaacgaagctccgttt actcatccaaagcctccggtgaggacaaaaagcaaagtcaaaggtgtagaaaaacaagta tcacgggacactgagacggatcgagaggaacaagaaccaacatcaggagtggtaaaagtt caagaccaaccaataaaacaacttctaaagccattaataaaacaggccaaagagaaacca gcatttgagaggaaccagccagttacagcaactgagaaaacagagcagcctgccaaacct ccattaaaacagccagttaaacccatgagaaaagaaccgaaaatggaccaggacgtgagc ctagcagtggagccaacgagaagggaggaagaacaacaaacaaaggtggcagaagacatt cctctcctttatatttctgaagatgaaactttctcagaggctttgactgagataccagct gagattctactccagacgacagaaccattgaaggagtctccgccggagatcgagatcagc accgaggatgagccacaaatgcaagaggctgcagtcaagatccaggctgctttcaaaggc ttcaagacacgcaaagatatgcgaccagtttttaaagaggtttttaagaaccggacagca gctcttcacggtatgctcactctaatgtgtgttgttgagggaaagccgagcgcagtacgg tggctcagaaatggccaacaaatttccaacgaccagagatgcaggattacgactacagat gatggagaatgcacacttgtgatcaagaacctgttaaacagcgacagtggaatttatacc tgtgaggtggtcaataagtttggtgtgacctcctacaatggaaacataacggtggtgcaa actccacagcctgcccctgtggcacagaggcccgtacacccacctcttgcagccattact cctttgcagctcgccccaacaaagcccgaagccccgcccaaagaccagaatgagaatctg ccacagagtcaagcgcaggtgcccacgtcagcagagaactatgcagaaagcatgaacgtg tctctgtgggaggcctacaccctgacagagcatgctcctcagcagaccctacaagagagg agacggtcctctgtcatggctgccagctccatgtcgagtccctctgattatgacacagct cccgatatgatggaacctgttgagatttccacaatcacaccgagggaagaaccaaaacca acagaacaagcagctccgaaggacgataacgaggagataacccaacctcccacgatgcta ttaaagatcaaaggggcccatgatggtaaaatgaggacaccatctccaaaacaccgtgcc cacacgcccttggacagcaccgtctctggatctgagtctgaaggagaagaggacagaaga gagacgtttgaaatatatgtggctcgagctcactgttgccctaacagtggcagtaaggag agttttattctgaaggagggccagtttgtagaggtcctggactctgttcatcctgacaga tggctggtgaggaccaaacccaccaaaaccaaccctggtcggcagggatggctgtgtcca gcatacttggagaagaagagaaaggagaccttcccccaactgagagcacgtcaagaggat cttgatggaattggatgtacaggagaagagtacaggagaggcctgagtcagttgatccaa ggcctgattgatggagaagaggagtttgtgagagagatgaagatgtttatatctcagcag ctaaattttctggactccagctaccacgtccccgttaacgtcctcaaccagaaagagatc attttcaggaacatcaaagacatcgtgttgttacatgagaggtgtgtccttcctgggttg agggagtgtgccacagatgatgatgtggccatgcatctgatcaaacacagagaagacttt gagaagtatattcactacatggtgggacaagctcaagcagaggcctgcatcgctgacaag actgtccaacagtttttcaaggagttaacagaagctggtaagctggacggtgctgttatg gatgtccttacattcctccagcaaccagtggaaagaattcaaacttacaaagctttacta aaggagttaatcaagaataaagctaagagtggccagagctgctatctgctggaggatgct ttctctttggtgtcctgccttccctggaggtcagacaacctgcacaaggtgtctctgatt gagaactacccggctcctcttattgccctgggtgagcccgtgcgtcagggatccttcaca gtgttggaggagactccagaaattaagaccccctctagagggcatcagagacaagtcttt ctcttcaaggaatgcattgtactgtgtaaactgaaaaaagacaccagcatgaaccgagac acctacagctttaagaacaaaatgaagctgaatgatgtggaaataaaggagactgtgggt ggagatgaaaggtcttggggcttgtggcacgaacacagaggctccataaggaggtacacg ctgcagggcagctccacgctggtcaaactgtcctggcttaaagacctgaaggagctacag caacgttccagcctgcctactaacagtcccccagtgtttgagttactgttgtctgactgc acgtcaaagatgggacaaacaatcaagctgacctgcaaagtgtcaggatctccaaaacca gagatcagctggctcaaagatggccttcctttggaggacgacccacgtcacatcatcaca gcagaccggtcgggctgttgtagtctcatcgtggacagcctcactgcggaggactctgga gagtacgcgtgctacgctaccagcttcatgggcagtgctggcactctggctaaggtggtg gtgcagactccacccagattcgtgagtcgactggaaagtgcttgtctcattgaaggagag gacatccagttctcctgctccacattcaccactcctttacccagaattaggtggttgaag gatggcaaagagttgactgagcagcagaaatacttgattatgaatgatgcacggagcggg atcctgtctctgaccgtcgtcggggcaactgaagcagatattgggcagtacgagtgtgag ctttggaatgaacttggtggcgtcaagtgcaaggcaggtttatgccccgcctatgtcccc ccgactgaccgtgagaatgaccaatcacaggacttacctcctaaagatcctgactcagag ggctggtctgctgcatttgtgaagaaatggttacaggctgatttcaacccaacttctaaa gccaagatgctttttcctcccgaaagtcctgaacacgctgagggtggtgctgaagtgact ctttatgcccccacgtcagccgatcaagcaccacagcagcccatgagttaccatgaggaa gaagaggagatctacatctcagagcaaatacaggaaattgcagatgctcctccctctatt cagatacccatcgaggacctgtttgtagagccgggtcacccatcgacatttatagccatc atcacaggaagaccagcacctaagataaagtggtacaaggacgaagaggagcttgcagcc aatgagaatgtgaagatgggacaacatggtgcccgctgctcattaaccatagtgtgcacc gagggtgaggacagtgggatgtacacctgcttcgctcacaacgactctggttatgcatcg tgtcaggctgagctgacagtagaagaaggacccctggagtttcaggagagagaggtggag ctgggaaaaagaaggaagctgttctctgtctatgacgtccacgatgaaattggaagggga acgttcggagtagtgaagcgcatcgtccacagaaggaccggtgaagtctttgcggccaag tttctgcctctgcggagcagcacccggaccagggccttccaggagagggacctgctgtcc cggctcgctcaccccagagtggcttgtctgctggacttcttttgcaccagacgcaccttg gtgctgattacagaaatctgctgttctcacgggcttctggatcatttattcctgaaagga tcagtctcagaaaaagagattcagtcattcatacagcaaattctggagggagttggtcac attcatagcatgaacatcttgcatctggacattaaacctgataatatcctcatggtgtat cccccaagagacgagatcaaaatctgtgactttggcttctgccaggaaatagacacatcc aggcaccagtacagcatgtttggcacgcctgaatttgttgccccagaaattgttcaccaa gaaccagtaactgtggccactgatatttgggccgtgggggttgttgcgtttctctgtctg gtgtgtcgatgcccttttgttggcgagactgaccgcgccacactgctgacggtgggggag gggactctgaactgggcagcccctgatatcatgtacaggagcccagaagccaagaacttt ctccacatgctccttcagcctgacccagagaagcgaccgtctgcctttgagtgcttgggc catgactggatccaggatgaacatgcaggagaagacacggatgaaatcaatacaaggagt ctgaaagcctttatttcaaaaagaaaatggcagcgttctctgacatgcattgggtcagtg ctcacgctgaggcccattcctgagctactagatgctcctctcagggagacggcagtgacg gtgccccgtgagccccaagaacacagcagtacctccccgagcagtggctcttcgtcggag tatgacgaggctgactcctgggactttttccagcactgcagccagactgaagaggaagag gaaacagaggaagactatgatcctttaatggagagagcacagatcccagatccttttccc agcttccaccgggatggagaagaggaaggggatttgacactaggcgaggaagaggatggg gagatagtaggaaggaggactgtattagagcggagtataagcaggcaatcggtcgcatca tcagaagtatcgtgtcaaaggacacctcagagggaacgtcggttcagcaaggacagcagc ccatcgctctacctgtcggatggggatgagggttcagggagtgacggaggtcgtattcct cggggtagcgtcatccgaagcactttttatagcaactctcatcagctttcgccgttgtct gccagacacatgacattaagggacaaatttcaagctaagaagcaggagaggggccgcaag ccactcaggaggagcttctcaggacgcctcaacgagcctcttattgaatatgtggaggat gagacagagaccagccgtggccagagacgagcatccatccagaccgcaatgcagaagtcc tgctcgtttgacagcggggtgggtttcgcccatgctaacgcaccacctcacagaaggagt aggtctcttgatgagtattcacgtcggtctcccacctcacccaaacgtgcgaacgccggt gaagaagaagggtcacaaagtctaaaggaagattttacagacgatgaagtggccgggaca aacttgctggcaatcccaaattctcagcgagccacgagaagaggctctgtcactcctgta caggtgattcagacttttagaggatcctctgttccttcgaggttagaccaagtacagaca gagggagataactttgctggctcccaggggtctctggctgagtcttttattttggagcat ggtggatctgagtcttcaagtagacttggctccaatgaagaactgagtcacggtcgtctc agagggagatacagatcaggagacggcgatggatatgatgatcagggtgagcgcctcatt gcaccatcgcctcgctctttccaagaagtaaaacctcgaagctcgtttccccgggcacca ccacgtaatcgcacacgctccaatcccaacctgtccacaaacagcagaggtcagctgggg acgccgctaatgccaagccccagtcccagcctctcttctctacaggctccagagaggcct cccagagcccgggacaagaaagagggtcacagcctccagaggcacgcatctgctccagcc cttgaagctcgaccacctacaggaaggtcaccaaaactgggactgctgaacatcttccgc aggcaatcctggactggccattcctactcccatctggaggacacagagttaggaccaact ctgggcgagatcatgaagcctgatacacccaccatgtctctaaggaagagaatgagagcg tcagcctcaagtctgaccaaactgttttccagatcctccagtaaagaggacgtgagtaaa ggagggccaatagtgaaaggatcagctcccactccacctgaaaggaagcgcagcagcagc ctcgagagtcccaaaaagaggagctcaaagctcttaccatccttcaaaatacctgcgttt aaaaagaaagacctgccagttcgccccagcaaggctgaggtgctacagttggatggaggc ggagtcctcctggcgtggaggccggttcactcaagtgatcccgtcacttactgcgtgcag tactgtaccgacgggggggagtggacagtcctgtcagaggacgtgacagacagctgctat gtggcaaaggacttaccgagaggagcttcttacgtgttcagggtgggttgtgtcacaaag atgggagcaggaccgttcagtgacgcttcagctcccgttgttatggcgactcatcctgaa gagatccacattcctctcattcagactgagtcactggggtcaaaggtcattggatcagaa caagcagcacacaagaactacaacttcctgcctgagatcaacaggggtcgtttcagcgtg gtagccctgtgcaggaacgctgagaccagccaggtgtttgcggccaagatcaccccttac caagcagagcagaggcagctggtgttgagggagtaccagctgctgaggaggcttcaccac ccccacctggttcagctgcactgtgctttcatcacctcctgctacctcgtgttagtagaa gagctttgtcccggcaaggagctcctctacagcctggctgcgagagatctgtacgcagag actcaagtggccgaggtgctggttcagatcctgagtgcggtcgactatctccacagccgt cgagtcatccacctggacctgaagtctgacaacatgctggtggacgactgtaaccacctg aagattgttgactttggctcggctcagtccttcacacccggacagcctttaaacatcgag cacatccagggcttttctgacagcagagactcctgcagcaaagctccggaaatcctcgaa ggtcagggtgttgggccagagaccgacatctgggctgttggagttttgtcgttcattatg ctgagtgctgacagcccgtttcatgcagagcacagctgggatcaagacagaaacatcagg aaagggaagatccagtttggacgctgttacccgggtctgtctgagggagccctgaacttc atgaagagcagcctgaacaacaaatcctgggggagacccactgcggccgagtgtctccag aatccgtggctccgtgcccatcgcgccccacacaaagcccgacactccaaagtctgcttc tccaccgacaaacttaaagcttacctcaagcagaaagaggagaaacgagatcaggtgcgc accaagcttcagggtcccttcttcttccagtga

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