Oreochromis niloticus (Nile tilapia): 100704221
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Entry
100704221 CDS
T06104
Symbol
pfas
Name
(RefSeq) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
onl
Oreochromis niloticus (Nile tilapia)
Pathway
onl00230
Purine metabolism
onl01100
Metabolic pathways
Module
onl_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
onl00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
100704221 (pfas)
Enzymes [BR:
onl01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
100704221 (pfas)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-GeneID:
100704221
NCBI-ProteinID:
XP_013121884
Ensembl:
ENSONIG00000002695
UniProt:
A0A669AZI3
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Position
LG23:39294254..39309877
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AA seq
1423 aa
AA seq
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MKYEIKLADYKPTSNLPQFEYWRSSLSKYWKSLFATTPIPTCACVLQFEWITRGCRGPAI
LPSIQSVSQSVCRPQLTQPLSVRPAGAEVTPGLQQRPGLIPDSVTAAALMAVVRFYSNEA
LNSRALQRAAKLYPHLLVTTELCYNVELTGCESLSTEQKGVLLWLFRHPLHAEPLSEKPN
LTEGSGEKLVEIGPRLNFSTAWSTNAVSICQSAGLTNVTRVELSRRFLIKPKTEQSVSEI
SGDMKKLIECLYDSMTECIYQHPITSFTVETEPQAVFDVDILGKGRAALESANDELGLAF
DSWDLDYYTLMFQRIERNPTSVECFDLAQSNSEHSRHWFFRGRMVIDGKEQKETLFSLIM
DTQRHSNQNNVIKFCDNSSGIKGMELEFIYPKDPSQASPYETRRSLRHVIFTAETHNFPT
GVSPFSGATTGTGGRIRDVQSAGRGGHVIAGTAGYCFGNLHIPGYDLPWECKGEGWEYPS
TFAPPLQVAIEASDGASDYGNKFGEPVLSGFARSFGMRLANGERREWIKPIMFSGGLGSI
EDIHVKKEAPEPGMEVVKIGGPVYRIGVGGGAASSVQVQGDNSSDRDLGAVQRGDAEMEQ
KMNRALRACLERSGGNPICSIHDQGAGGNGNVLKELSEPAGAVIYCSRFKKGDPTLSVLE
LWGAEYQESNALLLQPSDRSFLERVCQREKCPVDFVGNITGDGKIVLVHDEGGSGDVADS
GRCPVDLQLEWVLGKMPQKEFKVESLALNHQTLSLPAGLTVKDALHRVLRLPAVASKRYL
TNKVDRSVTGLVAQQQCVGPLHTPLADVAVVALSPFSLGGAATAIGEQPIKGLVCPAAGA
RMAVGEALTNLVFARVTELKDVKCSGNWMWAAKLPGEGACLWEACKAMCAVMGQLGVAID
GGKDSLSMAARVGKETVKAPGALVISAYAVSPDITATVTPDLEDPDGKGVLLWVPLSPGH
HRLGGSALAQCYSQLGDCSPDLDQPELLTACFNTTQKLIHDRLLSAGHDISDGGLLTCLL
EMAFAGNRGIDVELTSQGAGVMELLFSEELGLVLEVSQSDLETVCQRYSDAGVQCLHIGR
TYGFGPEAMVRVRVDGKEVLRELLPDLRAIWEDTSFQLERLQANELCIKQEEEGLSKRTQ
PYFKLTFNPSEMPTISQPARVAVVREEGSNGDREMSVSLYTAGFEVWDVTMQDLCTGSLT
LDPFKAVVFVGGFSYADVLGSAKGWAATVAYNPKAKAEFDRFRQREDTVSLGVCNGCQLL
ALLGWVGESEEGVESEVVLSHNKSGRFESRFVSVGIQDSPSIWLRGMEGSALGVWVAHGE
GLVQFRSSRAQDLIISGGLAPLRYLDDQGHPTEEYPLNPNGSPQGIAGLCSRDGRHLAMM
PHPERCTLSWQWPWAPRDFRPSLTPSPWLRMFKNAASWCSNQE
NT seq
4272 nt
NT seq
+upstream
nt +downstream
nt
atgaaatatgagataaaattggcagattataagccaacaagtaatttaccacagtttgaa
tactggcgatcgtctttgagcaaatactggaaatcactttttgctacaacacccattccc
acttgcgcatgcgtcttgcagtttgagtggatcacacgtgggtgcagaggtccagccatc
cttccatccattcagtcagtcagtcaatcagtgtgcagaccgcagctaacccagccgctt
tcagtccgtcctgcaggagcagaagttactccgggactccagcagagaccaggtttgatc
ccagacagcgtaactgctgctgcactcatggctgtcgtgaggttctacagtaatgaagct
ctgaatagtcgggccttacagagggcagccaagctctacccacatctgttagtcacgact
gagctgtgctacaatgtggaactgacaggctgtgagagtctcagcactgagcagaagggg
gttctactctggttgtttcgtcatcctctgcacgcagagccgctgtctgagaaaccaaac
ctcacagagggcagtggggagaaactggtggagatcgggcccaggttgaacttctccact
gcctggtccactaacgctgtgtccatctgccagagtgccggtctcactaacgtcacccga
gtcgagctgtcgcgcaggtttctcatcaagcccaagaccgagcagagtgtgagtgaaatc
agtggagatatgaagaagctgattgagtgtctgtatgacagcatgacggagtgcatctat
caacaccccatcacctccttcactgtggaaacagaacctcaggcggtgttcgacgtggac
atcctggggaagggtcgcgcagccttggagagcgctaatgatgagctgggcttggccttt
gactcctgggatctggactactacacattgatgttccagaggattgaaaggaaccccacc
agtgtggaatgttttgacctggcccagtccaatagtgagcacagtcgtcactggttcttc
cgggggcggatggtgatcgacgggaaggagcagaaggagactcttttcagcctcataatg
gacacgcagcggcacagcaaccagaacaacgtcatcaagttctgcgacaacagcagtggc
atcaaaggcatggagcttgagttcatttacccaaaagacccatcccaagcgagcccgtat
gagactcggcgatcactaagacatgtcatcttcacagcagagacgcacaacttcccgact
ggtgtatcaccgttcagcggagcaaccacagggactggtggtcgtatcagagatgtccag
agtgccggacgaggaggccacgtcattgctggcactgcgggatactgcttcgggaacctg
cacataccaggatatgatctcccatgggaatgtaaaggagagggatgggagtatccctcc
acctttgcccctcccctgcaggtggccattgaagccagcgatggagcgtcggactacggc
aacaagtttggagaacctgtcctctcgggctttgctcgttccttcggcatgcggctggct
aatggggagcgacgggagtggattaagccgatcatgttcagtggtggtctcggttctatc
gaagatatacacgtgaagaaagaagcgccagagcctggaatggaggtggtgaagatcgga
gggccggtgtacaggatcggtgtaggaggaggagcagcctcttctgttcaagtccagggg
gacaactccagcgacagggatctgggtgctgtccagaggggagatgctgagatggagcaa
aagatgaaccgtgctctcagggcatgcctggaaagaagcggtggaaatccaatctgcagt
atacatgatcagggggcaggaggaaatggtaatgtgctcaaggagctcagtgagccagca
ggagctgtgatatactgcagtagattcaagaaaggtgaccccacactgagtgtgctggag
ctgtggggggccgagtatcaggagagcaatgccctcctgctgcagccatcagaccggtcc
ttcctggagagggtgtgtcaaagggagaagtgtcctgttgactttgtgggaaacatcaca
ggagacggcaagattgtgctggtccatgatgagggaggaagtggagatgtggcagacagc
gggcgttgtcctgtggacctgcagctggagtgggttctgggaaagatgccgcagaaggag
tttaaggtggagtcactggccctgaatcatcaaacactgagtcttcctgctgggctgact
gtcaaagatgctctgcacagagttttacgtttgcctgctgtggcgtccaaacgctacctg
accaacaaggtggaccggtctgtgactgggttggttgcccagcaacagtgtgtcggccct
cttcacaccccattggccgatgtggctgttgttgctctatcacctttcagcctaggggga
gcagcaacagccattggggagcagccaattaaagggctggtgtgtcctgcagcaggggct
cgcatggctgtgggtgaggctctgaccaatctggtgtttgcaagggtaacagaactaaag
gatgtgaagtgcagtggtaactggatgtgggctgctaagctacctggagagggggcatgc
ctgtgggaagcctgcaaagccatgtgtgcagtcatgggtcagctgggagtggccatcgat
ggaggcaaggactctctgagcatggctgctagagttggaaaagagacggtcaaagctcca
ggtgctcttgttatttcagcatatgctgtttcccctgacatcactgctactgtgacgcct
gatctcgaggatccagatggcaaaggcgtgttgttgtgggttcctctcagtccaggccat
catcgtctgggaggctctgccctggctcagtgctacagccagctgggagactgctctcct
gacctggaccagccagaactattgacagcctgtttcaacaccactcagaaactcatacac
gatcgcctgctgagtgcaggtcatgacatcagtgacggaggccttcttacctgcttgcta
gagatggcgtttgcaggaaaccgtgggattgatgttgaattgacttcacaaggagctgga
gtcatggagctgttgttcagcgaggagctgggtttggttctggaggtttcacagtcagat
ttagaaactgtgtgccaaagatacagcgatgcaggcgtccagtgccttcatatcggcaga
acatatggctttggaccagaagccatggtcagggtccgtgtagatggaaaggaggtgctg
agggagctgctgcctgacctcagagcaatatgggaggacacgagtttccagctggagcgt
ctccaagccaatgagctgtgtattaaacaggaggaggaggggctatcaaagaggacacag
ccatactttaaactgacctttaacccctctgaaatgcccaccatcagccaacctgcacgt
gttgctgtggtcagagaggagggcagtaatggagatcgagagatgtctgtctccttgtac
acggcgggctttgaggtttgggatgtcaccatgcaagacctgtgcactggctcactaacg
ctggaccctttcaaagcagttgtctttgttggtggtttcagctatgcagacgttctggga
tcagctaaaggttgggcagctactgttgcctacaaccccaaggccaaggctgaatttgat
cgtttccgacaacgtgaggatacagtgagtctgggcgtatgtaatggctgtcagctgctc
gccttgctgggctgggtgggagagagcgaggaaggagtggaatctgaagtggtgctgagt
cacaataagtctggcaggtttgagtcgcgttttgtcagcgttgggatccaggactctcca
tccatctggctgagaggcatggagggctcagcgctgggagtctgggttgcacatggagaa
ggtcttgtgcaattccgtagctctcgggctcaggacctgattatttctggtggactagcc
cccctccgttaccttgacgaccagggtcatcccactgaagaataccctctcaaccctaac
ggctcaccgcagggtatcgcaggactctgctccagggacggcagacacctggccatgatg
ccccacccggagcgctgcaccctgagctggcagtggccctgggccccgagggacttcaga
ccttctctcacaccttcgccctggctgcgtatgttcaagaacgcagcttcttggtgcagc
aaccaagagtga
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