Orcinus orca (killer whale): 101269690
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Entry
101269690 CDS
T05247
Symbol
VAV2
Name
(RefSeq) guanine nucleotide exchange factor VAV2 isoform X11
KO
K05730
guanine nucleotide exchange factor VAV
Organism
oor
Orcinus orca (killer whale)
Pathway
oor04015
Rap1 signaling pathway
oor04024
cAMP signaling pathway
oor04062
Chemokine signaling pathway
oor04510
Focal adhesion
oor04517
IgSF CAM signaling
oor04519
Cadherin signaling
oor04650
Natural killer cell mediated cytotoxicity
oor04660
T cell receptor signaling pathway
oor04662
B cell receptor signaling pathway
oor04664
Fc epsilon RI signaling pathway
oor04666
Fc gamma R-mediated phagocytosis
oor04670
Leukocyte transendothelial migration
oor04810
Regulation of actin cytoskeleton
oor05135
Yersinia infection
oor05205
Proteoglycans in cancer
oor05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
101269690 (VAV2)
04024 cAMP signaling pathway
101269690 (VAV2)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
101269690 (VAV2)
04519 Cadherin signaling
101269690 (VAV2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
101269690 (VAV2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
101269690 (VAV2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
101269690 (VAV2)
04660 T cell receptor signaling pathway
101269690 (VAV2)
04662 B cell receptor signaling pathway
101269690 (VAV2)
04664 Fc epsilon RI signaling pathway
101269690 (VAV2)
04666 Fc gamma R-mediated phagocytosis
101269690 (VAV2)
04670 Leukocyte transendothelial migration
101269690 (VAV2)
04062 Chemokine signaling pathway
101269690 (VAV2)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
101269690 (VAV2)
09171 Infectious disease: bacterial
05135 Yersinia infection
101269690 (VAV2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101269690 (VAV2)
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Paralog
GFIT
Motif
Pfam:
RhoGEF
SH3_2
CAMSAP_CH
CH
SH3_1
SH3_9
SH2
SOS1_NGEF_PH
PH
C1_1
DUF7145
RHG20_PH
SH2_2
C1_2
CDC24
PLU-1
PH_10
DH_Alsin
ANC1_spectrin
DUF3848
Motif
Other DBs
NCBI-GeneID:
101269690
NCBI-ProteinID:
XP_004285057
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All DBs
Position
6:118407185..118586855
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AA seq
839 aa
AA seq
DB search
MEQWRQCGRWLIDCKVLPPNHRVVWPSAVVFDLAQALRDGVLLCQLLHNLSPGSIDLKDV
NFRPQMSQFLCLKNIRTFLKVCHDKFGLRNSELFDPFDLFDVRDFGKVISAVSRLSLHNL
AQTKGIRPFPSEETAENDDDVYRSLEELADEHDVGEDIYDCVPCEDEGDDIYEDIIKVEV
QQPMKMGMTEDDKRSCCLLEIQETEAKYYRTLEDIEKNYMTPLRLVLSPADMAAIFINLE
DLIKVHHSFLRAIDVSMMAGGSSLAKVFLDFKERLLIYGEYCSRMEHAQSTLSQLLAGRE
DFRQKVEECTLKVQDGKFKLQDLLVVPMQRVLKYHLLLKELLSHSTDRPERQQLKEALEA
MQDLAMYINEVKRDKETLKKIGEFQSSIENLQVKLEEFGRPKIDGELKVRSIVNHTKQDR
YLFLFDKAVIVCKRRGDSYELKEIIELLFHKMTDDPMNNKDVKKWSYGFYLIHLQGKQGF
QFFCKTEDMKRKWTEQFEMAMSNIKPDKATANQHSFQMYTFDKTTNCRACRMFLRGTFYQ
GYLCTKCGVGAHKECLEVTPPCKISSPADLDTSGVGPGPKMVAVQNYHGNPAPPGKPVLT
FQTGDVIELLRGDPESQWWEGRLVQTRKSGYFPSSSVKPCPVDGRPPISRPPSRDMDYTA
YPWFAGNMERQQTDNLLKSHASGTYLIRERPAEAERFAISIKFNDEVKHIKVVEKDSWVH
ITEAKKFESLSELVEYYQCHSLKESFKQLDTTLKYPYKSRERVASRASSRSPVFTPRVIG
TAVARYNFAARDLRELSLREGDVVKIYSRIGGDQGWWKGETNGRIGWFPSTYVEEEGIQ
NT seq
2520 nt
NT seq
+upstream
nt +downstream
nt
atggagcagtggcggcagtgcggccgctggctcatcgactgcaaggtcctgccgcccaac
caccgggtcgtgtggccctcggccgtggtcttcgacctggcccaggcgctgcgcgacggc
gtcctcctgtgccagctgctgcacaacctctcccccggctccatcgacctcaaggacgtc
aacttccggccgcagatgtcccagttcctgtgtttgaagaacattcgcaccttccttaaa
gtctgccacgacaaatttggactcaggaacagcgagctgtttgaccccttcgacctcttt
gatgtccgagactttgggaaggtcatctcggccgtgtcgaggctctccctgcacaacttg
gctcagaccaaaggaatcaggcccttcccctcggaggagaccgcggagaatgacgatgac
gtctaccgcagcctggaggaactggcagatgagcatgacgtgggggaggacatctacgac
tgcgtcccgtgcgaggatgaaggggacgacatttatgaggacatcatcaaggtggaagtg
cagcagcccatgaaaatgggcatgacggaggacgacaagagaagctgctgcctgctggag
atccaggagacggaagccaagtactaccggaccctggaggacatcgagaagaactacatg
acccctctgaggctcgtgctgagcccggcggacatggcggccatcttcatcaacctggag
gacctaattaaggtgcatcacagcttcctgagggccatcgacgtgtccatgatggcgggg
ggcagctcgctggccaaggtcttcctggacttcaaggaaaggctcctgatctacggggag
tactgcagccgcatggagcacgcgcagagcacgctgagccagctgctggccggcagggag
gacttcagacagaaagtcgaggaatgcaccctgaaggtccaagacgggaagttcaagctg
caggacctgctggtggtccccatgcagagggtgctcaaataccacctgctcctcaaggaa
ctcctgagccattccaccgaccggcccgagaggcagcagctcaaagaagcgctggaggcc
atgcaggacctggcgatgtacatcaacgaagtcaaacgggacaaagagaccctgaagaaa
atcggcgagtttcagagttccatagagaacctgcaagtgaaactggaggaatttgggaga
ccaaagatcgacggggagctgaaggtccggtccatagtgaaccacaccaagcaagacagg
tacctgttcctgtttgacaaggcggtcattgtgtgcaagaggaggggcgacagctacgag
ctgaaggagatcatcgagctgcttttccacaagatgaccgacgaccccatgaacaacaag
gacgtcaagaagtggtcctacggtttctatctaattcaccttcaaggcaagcaaggcttc
cagtttttctgcaagacggaagacatgaagaggaagtggacggaacagtttgagatggcc
atgtcaaacatcaagcccgacaaagccaccgccaaccagcacagcttccagatgtacacg
tttgacaagaccaccaactgcagagcgtgcaggatgttcctcagaggcaccttctaccag
ggttacctgtgcaccaagtgtggcgtcggggcacacaaggagtgcctggaagtgacccct
ccctgcaagatcagttctcctgcagacctggacacctctggagtggggccaggtcccaag
atggtggccgtgcagaattaccatggcaaccctgctccccccgggaagccggtgctgacc
ttccagacgggtgatgtgattgagctgctgagaggcgaccctgagtctcagtggtgggag
ggtcggttggtgcaaaccaggaagtcaggttacttccctagctcgtctgtgaagccctgt
ccagtggatggaaggccgcccatcagccggccgccgtcccgggatatggactacaccgca
tacccctggtttgccggcaacatggaacggcagcagaccgacaacctgctcaaatcccac
gccagcgggacctacctaatcagggagcggccggccgaggccgagcgttttgccataagc
atcaaattcaacgacgaggtgaaacacatcaaggtggtggagaaggacagctgggtgcac
atcaccgaagccaagaaatttgagagcctctcagagttggtagagtactaccagtgccac
tcgctcaaggagagcttcaagcagctggacaccacgctcaagtacccctacaagtcacgg
gaacgcgtggcctctagggcctccagccggtccccagtgtttacgccccgcgtcatcggc
acagccgtggccaggtacaacttcgctgcccgggacctgcgggagctctcgctgcgagaa
ggcgacgtggtgaagatctacagccgcatcggtggggaccagggctggtggaagggcgag
accaacggccggattggctggtttccttcaacgtacgtagaagaagagggcatccagtga
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