Orcinus orca (killer whale): 101269912
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Entry
101269912 CDS
T05247
Symbol
NDUFS1
Name
(RefSeq) NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
KO
K03934
NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:
7.1.1.2
]
Organism
oor
Orcinus orca (killer whale)
Pathway
oor00190
Oxidative phosphorylation
oor01100
Metabolic pathways
oor04714
Thermogenesis
oor04723
Retrograde endocannabinoid signaling
oor04932
Non-alcoholic fatty liver disease
oor05010
Alzheimer disease
oor05012
Parkinson disease
oor05014
Amyotrophic lateral sclerosis
oor05016
Huntington disease
oor05020
Prion disease
oor05022
Pathways of neurodegeneration - multiple diseases
oor05208
Chemical carcinogenesis - reactive oxygen species
oor05415
Diabetic cardiomyopathy
Module
oor_M00143
NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09100 Metabolism
09102 Energy metabolism
00190 Oxidative phosphorylation
101269912 (NDUFS1)
09150 Organismal Systems
09156 Nervous system
04723 Retrograde endocannabinoid signaling
101269912 (NDUFS1)
09159 Environmental adaptation
04714 Thermogenesis
101269912 (NDUFS1)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
101269912 (NDUFS1)
09164 Neurodegenerative disease
05010 Alzheimer disease
101269912 (NDUFS1)
05012 Parkinson disease
101269912 (NDUFS1)
05014 Amyotrophic lateral sclerosis
101269912 (NDUFS1)
05016 Huntington disease
101269912 (NDUFS1)
05020 Prion disease
101269912 (NDUFS1)
05022 Pathways of neurodegeneration - multiple diseases
101269912 (NDUFS1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
101269912 (NDUFS1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
101269912 (NDUFS1)
Enzymes [BR:
oor01000
]
7. Translocases
7.1 Catalysing the translocation of protons
7.1.1 Linked to oxidoreductase reactions
7.1.1.2 NADH:ubiquinone reductase (H+-translocating)
101269912 (NDUFS1)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Molybdopterin
Fer4_Nqo3
Fer4_NDSU1
Fer2_4
NADH-G_4Fe-4S_3
NADH_dhqG_C
Fer2
Motif
Other DBs
NCBI-GeneID:
101269912
NCBI-ProteinID:
XP_004262857
LinkDB
All DBs
Position
7:complement(90879380..90909611)
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AA seq
727 aa
AA seq
DB search
MLRIPVRRALVSLSKSPKGCVRTTATAASNLIEVFVDGQSVMVEPGTTVLQACEKVGMQI
PRFCYHERLSVAGNCRMCLVEIEKAPKVVAACAMPVMKGWNILTNSEKTKKAREGVMEFL
LANHPLDCPICDQGGECDLQDQSMMFGSDRSRFLEGKRAVEDKNIGPLIKTIMTRCIQCT
RCIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNIIDICPVGALTSKPYAFTA
RPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINEEWISDKTRFAYDGLKRQ
RLTEPMVRNEKGLLTYTTWEDALSRVAGMLQSFQGNDVAAIAGGLVDAEALVSLKDLLNR
VDSDTLCTEEVFPTTGAGTDLRSNYLLNTTIAGVEETDVVLLVGTNPRFEAPLFNARIRK
SWLHNDLKVALIGSPVDLTYSYDHLGDSPKILQDIASGSHPFSQVLKEAKKPMVVLGSSA
LQRNDGAAILAAVSNIAQKIRMSSGVTGDWKVMNILHRIASQVAALDLGYKPGVEAIRKN
PPKVLFLLGADGGCITRQDLPKDCFIIYQGHHGDVGAPIADVILPGAAYTEKSATYVNTE
GRAQQTKVAVTPPGLAREDWKIIRALSEIAGMTLPYDTLDQVRNRLEEVSPNLVRYDDVE
GANYFQQANELSKLVNQHLLADPLVPPQLTIKDFYMTDSISRASQTMAKCVKAVTEGAHA
VEEPSIC
NT seq
2184 nt
NT seq
+upstream
nt +downstream
nt
atgttaaggatacctgtaagaagggccttagtgagcctttctaagtctcctaaaggatgt
gttcgaacaactgccacagcagcaagcaacttgattgaagtatttgttgatggtcagtct
gtcatggtggaaccaggaactaccgtcctccaagcttgtgagaaggttggcatgcagatc
cctcgattctgttatcatgaaaggttgtctgttgctggaaactgcaggatgtgccttgtt
gaaattgagaaagctcctaaggttgtagctgcttgtgccatgccagtaatgaaaggttgg
aatatcctgacaaactcagagaaaactaagaaagccagggaaggtgtgatggagttccta
ctagcaaatcacccactggattgtcctatttgtgaccagggaggtgaatgtgatctgcag
gaccagtccatgatgtttggaagtgataggagccggtttttagaggggaaacgtgctgtg
gaggacaagaacattgggccattgataaaaaccattatgactagatgtatacagtgtact
cggtgcatcagatttgcaagtgagattgcaggagtagatgatctgggaacaacaggcaga
ggaaatgatatgcaagttggcacatacattgaaaagatgttcatgtctgaactttctggg
aatatcattgacatctgccctgtaggtgccctgacctctaagccctatgcctttactgct
cggccttgggaaacaagaaagacagaatccattgatgtaatggatgcagttggaagtaat
attgtggtcagcacaagaactggagaggtaatgaggattttgccaaggatgcatgaggac
atcaatgaagagtggatctctgataaaaccagatttgcctatgatgggctaaaacgtcaa
agacttaccgagccgatggtcagaaatgaaaaggggcttttaacatacaccacctgggag
gacgcactctctcgtgtagctggaatgttgcagagttttcaaggcaacgatgtggcagca
attgcaggtggcttggtggatgctgaagccctagtatctctcaaagatttacttaataga
gtggactctgacaccctatgcactgaagaggtgttccctaccacaggagctggcacagat
ctacgttccaattatcttcttaatactacaattgccggtgtggaagagacagatgttgtc
ctcctggttggtacaaatccacgttttgaggcaccactatttaatgctagaattcgaaag
agttggctccacaatgacttaaaagtggcccttataggcagccctgttgatctcacttac
agctacgaccatctgggagattctcccaaaattcttcaagacattgcttcgggcagccat
cctttcagccaggtcctaaaggaagctaaaaaaccaatggtggttttaggcagttctgca
ctccaaagaaatgatggggcagcaattcttgcagctgtttccaacattgctcaaaagatt
cggatgagtagtggtgttactggtgattggaaagttatgaatatccttcataggattgca
agccaagtagctgctttggaccttggctataaacctggggtggaagcaattcggaagaac
cctcccaaagtgctgtttcttctgggagcagatggaggttgtattactcgacaggatttg
ccaaaggattgtttcattatttatcaaggacatcatggtgatgttggagctcctatagcg
gatgttattctccccggcgctgcttacacagagaagtctgctacttatgtcaatactgag
ggccgagctcagcagactaaagtagcagtgacacctcctggcttggcaagagaagactgg
aaaattataagagcactttctgagattgcaggtatgactcttccatatgatactctggat
caagtaaggaacagattggaagaagtctctcctaatcttgttcgatatgatgatgtcgaa
ggagctaattatttccagcaagcaaatgagctttccaagctcgtgaaccaacaccttctt
gctgatccacttgttccacctcagctaacaataaaagacttctacatgacagattcaatt
agcagagcctcacagacaatggctaaatgtgtcaaagctgtcacagagggtgcccatgca
gtagaggaaccatccatatgctga
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