Orcinus orca (killer whale): 101270052
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Entry
101270052 CDS
T05247
Symbol
PLA2G4E
Name
(RefSeq) cytosolic phospholipase A2 epsilon isoform X1
KO
K16342
cytosolic phospholipase A2 [EC:
3.1.1.4
]
Organism
oor
Orcinus orca (killer whale)
Pathway
oor00564
Glycerophospholipid metabolism
oor00565
Ether lipid metabolism
oor00590
Arachidonic acid metabolism
oor00591
Linoleic acid metabolism
oor00592
alpha-Linolenic acid metabolism
oor01100
Metabolic pathways
oor04010
MAPK signaling pathway
oor04014
Ras signaling pathway
oor04072
Phospholipase D signaling pathway
oor04217
Necroptosis
oor04270
Vascular smooth muscle contraction
oor04370
VEGF signaling pathway
oor04611
Platelet activation
oor04664
Fc epsilon RI signaling pathway
oor04666
Fc gamma R-mediated phagocytosis
oor04724
Glutamatergic synapse
oor04726
Serotonergic synapse
oor04730
Long-term depression
oor04750
Inflammatory mediator regulation of TRP channels
oor04912
GnRH signaling pathway
oor04913
Ovarian steroidogenesis
oor04921
Oxytocin signaling pathway
oor05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09100 Metabolism
09103 Lipid metabolism
00564 Glycerophospholipid metabolism
101270052 (PLA2G4E)
00565 Ether lipid metabolism
101270052 (PLA2G4E)
00590 Arachidonic acid metabolism
101270052 (PLA2G4E)
00591 Linoleic acid metabolism
101270052 (PLA2G4E)
00592 alpha-Linolenic acid metabolism
101270052 (PLA2G4E)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101270052 (PLA2G4E)
04014 Ras signaling pathway
101270052 (PLA2G4E)
04370 VEGF signaling pathway
101270052 (PLA2G4E)
04072 Phospholipase D signaling pathway
101270052 (PLA2G4E)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
101270052 (PLA2G4E)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
101270052 (PLA2G4E)
04664 Fc epsilon RI signaling pathway
101270052 (PLA2G4E)
04666 Fc gamma R-mediated phagocytosis
101270052 (PLA2G4E)
09152 Endocrine system
04912 GnRH signaling pathway
101270052 (PLA2G4E)
04913 Ovarian steroidogenesis
101270052 (PLA2G4E)
04921 Oxytocin signaling pathway
101270052 (PLA2G4E)
09153 Circulatory system
04270 Vascular smooth muscle contraction
101270052 (PLA2G4E)
09156 Nervous system
04724 Glutamatergic synapse
101270052 (PLA2G4E)
04726 Serotonergic synapse
101270052 (PLA2G4E)
04730 Long-term depression
101270052 (PLA2G4E)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
101270052 (PLA2G4E)
09160 Human Diseases
09161 Cancer: overview
05231 Choline metabolism in cancer
101270052 (PLA2G4E)
Enzymes [BR:
oor01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.1 Carboxylic-ester hydrolases
3.1.1.4 phospholipase A2
101270052 (PLA2G4E)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
cPLA2_C2
PLA2_B
C2
Motif
Other DBs
NCBI-GeneID:
101270052
NCBI-ProteinID:
XP_049562626
LinkDB
All DBs
Position
2:116044805..116089464
Genome browser
AA seq
726 aa
AA seq
DB search
MLQKETLVLASHHPSHPSQAEDGRPSATCTLEEELSPCHLLTVRVIRMKNVQQADVVSQT
DCFVSLWLPTSSPKRLRTRTISNCRNPEWNESFKFQIQTRVKNVLELSVCDDDTLTPDDH
FLTVLYDLTKLCFREKTHVKFPLNREGMEELEVEFLLEESPSPPESLITNGVLVSRQMSC
LEVHAESRRQKNRKVKGLPVTVTESFEHTQHISHCLEPCGPNPACFHYPKYFQPQVHVEV
PKSQWSSVLCCCSACKNDPVCQSLDCLPDGQAVTLPVNKNCELHMKSTPCSEALDVRLGF
SLCQAELEFLQKRRVVVAEALKQVLQLEEDLQADEVPLISIMATGGGTRSMTAMYGHLLG
LQKLNILNCASYITGLSGATWTMATLYRDPDWSSKNLELAILEARRHVVKDKTPALFPDQ
LLKFREELQQRRQEGYKVTFTDFWGLLVETCLGDERYECKLSDQRAALCQGQNPLPIYLT
INVKDDVSNQDFREWFEFSPYEVGLQKYGAFIPTELFGSEFFMGRLMRRIPESRICYMLG
LWSSIFSLNLLDAWNLSHTSEEFFHRWTRERVHDIEDEPLLPEIPKCDANMLDTTVVMPG
SWLSNTFRNILTSRAFLSEFHNFLLGLQMHTDYYQNGQFSTWKDSVLDGFPNKLTASVNH
LCLLDTAFVINSSYPPVLRPERKADLIIHLNYCAGSQTKNFCCQCPCPHGEPQPPPLPPL
QETLQH
NT seq
2181 nt
NT seq
+upstream
nt +downstream
nt
atgctgcagaaggagacgcttgtcttagcctcccaccacccgtcacacccaagccaagca
gaagatggcaggccctccgccacctgcaccttggaggaggagctgtctccatgccacctg
ctgacagtgagggtcatccggatgaaaaacgtccaacaggctgacgtggtaagccagaca
gactgctttgtgagcctctggctgcccacaagctctcctaagaggctgaggactaggacc
atctccaactgccgaaacccagagtggaatgaaagcttcaagttccagatccagacccgg
gtgaagaacgtgctagagctgagcgtctgtgatgacgacacgttgacaccagatgaccat
ttcttgacagttctctatgacctcaccaagctctgcttccgagagaaaacccacgtgaag
ttcccactcaacagagagggcatggaggagctggaggtggagttcctgctggaggagagc
ccctctccacctgagagtctcatcacgaatggcgtgctggtgtctcgacaaatgtcctgc
ctggaggttcatgcagaatccaggagacagaagaataggaaagtgaagggcctcccggtg
acagtgacggagtccttcgagcacacccagcacatctcacactgcctggagccctgcggc
ccaaaccctgcctgcttccactaccccaagtacttccagccccaggtccacgtggaggtg
cccaagagccagtggagctctgtgctttgctgctgcagtgcgtgcaagaacgaccctgtg
tgccagtccctggattgcctccctgacggccaggcggtgaccctgcctgtgaacaagaat
tgtgaattacacatgaaatctacaccctgctccgaggcactggacgtgcggctaggcttc
agcctgtgccaggcagagctggagttcctgcagaagcggagggtggtggtggctgaggcg
ctgaagcaggtgttgcagctggaggaggacctgcaggcagacgaggtcccactgatatcc
atcatggccactgggggtgggacaagatccatgactgccatgtatggccacctgctgggg
ctgcagaagctgaacatcctgaactgtgccagctacatcactggcctgtcaggggccacc
tggaccatggctaccttgtaccgtgaccctgactggtcctccaaaaacctggagcttgcc
atcctcgaggcgcggaggcacgtagtcaaggacaagacgcccgctctgttcccagatcag
ctcctcaaattccgggaggagctgcagcagcgcaggcaggaaggctacaaagtcaccttc
acagacttctggggtctgctggtcgagacctgtctgggggacgagagatatgaatgcaaa
ctgtcagatcagcgtgctgctttgtgtcagggccagaaccccctgcctatctacctcacc
atcaatgtcaaggatgatgtaagcaaccaggatttcagagagtggttcgagttctctccc
tacgaggtgggtctgcagaagtatggagccttcattcccaccgagctcttcggctccgag
ttcttcatggggcggctgatgaggaggatcccagagtcgcggatatgctacatgctaggt
ctgtggagcagcatcttctccctgaacctgctcgatgcctggaatttgtcccacacctcg
gaggagtttttccacaggtggacaagggagagagtgcatgatatcgaagatgagccactc
ctacctgaaatccctaaatgtgatgccaacatgctggacaccacggtggtgatgccaggg
tcatggctgtccaatactttccgcaacatcctcacctcccgggcctttttgtctgagttc
cacaacttcctgctggggctgcagatgcacaccgactactaccagaatggccagttctcc
acgtggaaggactcggtgctagatggcttcccaaacaagctgacagcgtccgtgaaccac
ttgtgcctgctggacactgcattcgtcatcaactccagctacccgcccgtcctcaggccg
gagagaaaagctgacctcatcatccacctcaattactgtgctgggtcccagacaaagaac
ttctgctgccagtgtccttgtccccacggtgagccacagccaccacccctcccgcctctg
caggagaccctccaacactag
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