Orcinus orca (killer whale): 101270209
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Entry
101270209 CDS
T05247
Symbol
TOP2B
Name
(RefSeq) DNA topoisomerase 2-beta isoform X2
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
oor
Orcinus orca (killer whale)
Pathway
oor01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
101270209 (TOP2B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
oor03032
]
101270209 (TOP2B)
03036 Chromosome and associated proteins [BR:
oor03036
]
101270209 (TOP2B)
Enzymes [BR:
oor01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
101270209 (TOP2B)
DNA replication proteins [BR:
oor03032
]
Eukaryotic type
DNA Topoisomerases
101270209 (TOP2B)
Chromosome and associated proteins [BR:
oor03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
101270209 (TOP2B)
Centrosome formation proteins
Centriole proteins
101270209 (TOP2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
DUF7180
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
101270209
NCBI-ProteinID:
XP_004271952
LinkDB
All DBs
Position
5:3252394..3351418
Genome browser
AA seq
1617 aa
AA seq
DB search
MAKAGGGGGSGAGAGGLGALTWVNNAAKKEESETANKNDSSKKLSVERVYQKKTQLEHIL
LRPDTYIGSVEPLTQLMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTC
IKVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNG
YGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPDLS
KFKMEKLDKDIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETGV
ALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKK
NKAGVSVKPFQVKNHIWVFINCLIENPSFDSQTKENMTLQPKSFGSKCQLSEKFFKAASN
CGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGRHSLECTLILTEGDS
AKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDD
AESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNK
QELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPE
DDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELI
LFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQAL
MMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLARLLFPAVDDN
LLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLEGLD
PHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPML
NGTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLFD
HMGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKIT
IENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEEETQNQHDDSSSDSGTPSGPDFNY
ILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVEVQERE
DLLAGMAGKAIKGKVGKPKVKKLQLEETMPSPFGRRIVPEITAMKADASKKLLKKKKGDL
DTTAVKVEFDEEFSGAQVEGAGEEALIPSAPINKGPKPKREKKEPGTRVRKAPTSSGKPS
AKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDD
DDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKASPEKSSHDKGQDYGNL
FSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTEKVPSKTVAAKKGKPSLDTAPKP
KRTPKQKKVETVNSDSDSEFGVPKKTTAPKGKGRGAKKRKASGSENEGDYNPGRKTSRTT
SKKPKKTSFDQDSDVDIFPSDFTSEPPSLPRTGRARKEVKYFAESDEEEDVDFAMFN
NT seq
4854 nt
NT seq
+upstream
nt +downstream
nt
atggccaaggcgggcggcggcggcggcagcggcgcgggagctggcggcctcggggcgctg
acttgggtgaacaatgctgcaaaaaaagaagagtcagaaactgcaaacaaaaatgattct
tcaaagaagttgtctgttgagagagtgtatcagaaaaagacacaacttgaacatattctc
cttcgtcctgatacgtacattgggtcggtggagccattgacacagctcatgtgggtgtat
gatgaagatgtaggaatgaattgcagagaggttacctttgtgccgggtttatacaagatc
tttgatgaaattttggttaatgcagctgacaataaacagagggataagaacatgacctgt
attaaagtttctattgatcctgaatctaacatcataagcatctggaataatgggaaaggc
attccggtagtagaacacaaagtagagaaagtttatgttcctgcattaatttttggacag
cttttaacatccagtaactatgatgatgatgagaaaaaagtaacaggtggtcgcaatggt
tatggtgcaaaactttgtaatattttcagtacaaagtttacagtagaaactgcttgcaaa
gaatacaaacatagttttaagcagacatggatgaataatatgatgaagacttctgaagcc
aaaattaaacattttgatggtgaagattacacatgcataacattccaaccagatctgtcc
aagtttaagatggagaaacttgacaaggacattgtggctctcatgaccagaagagcttac
gatttggctggttcgtgcaaaggagtcaaggttatgtttaatggaaagaaattgcctgta
aatggatttcgcagttatgtagatctttatgtgaaagacaagttggatgaaactggagtg
gccctaaaagttattcatgaacttgcaaatgaaagatgggatgtttgtctcacactgagt
gaaaaaggattccagcaaatcagctttgttaatagcattgcaacaacaaaaggtggacgg
catgtggattatgtagtagaccaagttgttggtaaactgattgaagtagttaagaaaaag
aacaaagctggtgtgtcagtgaaaccatttcaagtaaaaaaccatatatgggtttttatt
aactgccttatcgaaaatccaagttttgattctcagactaaggaaaacatgactttgcag
cccaaaagttttggatccaaatgccaactgtcagaaaagttttttaaagcagcctctaac
tgtggcattgtggaaagtatcctgaactgggtgaaatttaaggctcagacgcagctgaac
aagaagtgttcatcagtaaagtacagtaaaatcaaaggtattcccaaactggacgatgct
aatgatgctggtggcaggcactccctggagtgcacgctgatactgacggaaggggactct
gctaagtcgctggccgtgtccggactgggcgtgattgggagggacaggtacggggtcttc
cccctcaggggcaagatcctcaacgtgcgggaggcctctcacaagcagatcatggagaat
gcagaaataaacaatatcattaagatagttggtctacaatacaagaaaagttacgatgat
gcagaatcgctgaaaaccttacgctatgggaagattatgattatgactgatcaggatcaa
gatggttctcacataaaaggcctgcttattaatttcatccatcacaattggccatcactt
ttgaagcatggttttcttgaagagttcattactcctatcgtaaaggctagcaaaaataag
caggaactttccttctatagtattcctgaatttgatgagtggaaaaaacatatagaaaac
cagaaagcctggaaaataaaatactacaaagggttgggtaccagtacagctaaggaagcc
aaggaatattttgctgatatggaaaggcaccgcatcttatttagatatgctggtcctgaa
gatgatgctgccattaccttggcattcagtaagaagaagatcgatgacagaaaagaatgg
ttaacaaattttatggaagatcggagacagcgtaggttacatggcttaccagagcaattt
ttatatggtacagcaacaaagcatttgacttacaatgatttcatcaacaaggaattgatt
ctcttctcaaactcagacaatgaaaggtctataccatctcttgttgatggctttaaacca
ggccaacgaaaagttttatttacctgtttcaagaggaatgataaacgcgaagtaaaagtt
gcacagttggctggatctgttgccgagatgtctgcttatcatcatggagaacaagcactg
atgatgactattgtgaacttggctcagaactttgtggggagtaacaacattaacttgctt
cagcccatcggtcagtttggaactcggcttcacgggggcaaagatgctgcaagtcctcgt
tacattttcacgatgttaagctctttggcaagactgcttttccctgctgtggacgacaac
ctgcttaaattcctttatgatgataatcaacgcgtagagcccgagtggtatattcccata
atccccatggttttaataaatggtgctgagggtatcggcacaggatgggcttgtaaacta
cccaactatgatgctagggagattgtgaacaacgtcagacggatgctggaaggcttggat
cctcatcccatgcttccaaactacaaaaactttaaaggaacaatccaagaacttggtcaa
aaccaatatgcagtcagtggtgaaatatttgtggtggatagaaacacagtggagattaca
gagcttcccgttagaacttggacacaggtatacaaagaacaggttttagaacctatgcta
aatggaacagataaaacaccagcattaatttctgattataaagaataccatacggataca
actgtgaaatttgtggtgaaaatgactgaagagaaactagcacaagcagaagctgctgga
ttgcacaaagtttttaaacttcaaactactcttacttgtaattccatggtactctttgat
catatgggatgtctgaagaagtatgaaactgtgcaagacattttgaaagaattctttgat
ttacgattaagctattatggtttacgtaaggagtggcttgtaggaatgctgggagcagaa
tctacaaagcttaacaatcaagcccgtttcattttagagaagatacaagggaagattact
atagagaataggtcaaagaaagatttgattcaaatgttagtccagagaggttatgaatct
gacccagtgaaagcctggaaagaagcacaagaaaaggcagcagaagaggaagaaacacaa
aaccagcatgatgatagttcctctgattcaggaactccttcaggccctgattttaattat
attttaaatatgtctctatggtctcttactaaagaaaaagttgaagaactgattaaacag
agagatgcaaaagggcgagaggtcaatgatcttaaaagaaaatctccttcagatctttgg
aaagaagatttagcagcttttgttgaagaactggataaagtggaagtgcaagaacgagaa
gatcttctggctgggatggctggaaaagcaataaaagggaaagttggcaaacctaaggtg
aagaagcttcaactggaagagacaatgccctcacctttcgggagaagaatagttcctgaa
attactgccatgaaggcagatgccagtaagaagttgctgaagaagaaaaagggtgatctc
gataccacagcagtgaaagtggaatttgatgaagaattcagtggtgcacaagtagaaggt
gcaggagaagaggcattgatcccgtcagctcctataaataaaggtcccaaacccaaaagg
gagaaaaaggagcctggtaccagggtgagaaaagcacctacatcatctggtaaacccagc
gcaaagaaagtgaagaaacggaatccttggtcagacgatgaatccaagtcagaaagtgac
ttggaagaaacagaacctgtggttattccacgagattctttacttaggagagcggctgct
gaaaggcctaagtacacatttgatttctcagaagaagaggacgacgatgctgatgatgac
gatgacaataatgatttagaggaattgaaagttaaagcatctcccataacaaatgatgga
gaagatgaatttgtcccttcagatggcctagataaagatgaatatacgttttcaccaggc
aaatccaaagctagtccagaaaagtcttcccatgacaaaggtcaggattacgggaatctc
ttctcatttccttcatactctcagaagtcagaagatgattcagctaaatttgacagtaat
gaagaagattctgcttctgtcttttcaccatcatttggtctgaaacaaacagaaaaagtt
ccaagtaaaacagtagctgctaagaagggaaaaccatctttagatacagcccccaagccc
aagagaactcccaaacagaagaaagtagagactgtaaactctgactcggattccgaattt
ggcgttccaaagaagacaacagcacccaaaggtaaaggccgaggggcaaagaagaggaaa
gcatctggctctgaaaacgaaggtgattataaccctggcaggaaaacctctagaacaaca
agcaagaaaccgaagaaaacatcttttgatcaggattcagatgtggacatcttcccatca
gacttcacttctgaaccaccttctctgccgcggaccggtcgggctaggaaagaagtaaaa
tattttgcagagtctgatgaagaagaagatgttgattttgcgatgtttaattag
DBGET
integrated database retrieval system
