Orcinus orca (killer whale): 101270334 Help Entry 101270334         CDS       T05247                                  Symbol TOP2A Name (RefSeq) DNA topoisomerase 2-alpha   KO K03164   DNA topoisomerase II [EC:5.6.2.2] Organism oor  Orcinus orca (killer whale) Pathway oor01524   Platinum drug resistance Brite KEGG Orthology (KO) [BR:oor00001]  09160 Human Diseases   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     101270334 (TOP2A)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03032 DNA replication proteins [BR:oor03032]     101270334 (TOP2A)    03036 Chromosome and associated proteins [BR:oor03036]     101270334 (TOP2A) Enzymes [BR:oor01000]  5. Isomerases   5.6  Isomerases altering macromolecular conformation    5.6.2  Enzymes altering nucleic acid conformation     5.6.2.2  DNA topoisomerase (ATP-hydrolysing)      101270334 (TOP2A) DNA replication proteins [BR:oor03032]  Eukaryotic type   DNA Topoisomerases    101270334 (TOP2A) Chromosome and associated proteins [BR:oor03036]  Eukaryotic type   Chromosome condensation proteins    Other regulators of chromosome condensation     101270334 (TOP2A)   Centrosome formation proteins    Centriole proteins     101270334 (TOP2A) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  DNA_topoisoIV TOPRIM_C DNA_gyraseB DTHCT HATPase_c Toprim Microp_apicomplexa_20 Motif Other DBs NCBI-GeneID:  101270334 NCBI-ProteinID:  XP_012393194 LinkDB All DBs Position 19:41870579..41896101 Genome browser AA seq 1533 aa AA seqDB search MEMSPLQPVDDNMQVNKTKKNEDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVESVTQQ MWVYDEDIGINCREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWN NGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDEEKKVTGGRNGYGAKLCNIFSTKFTVE TASREYKKMFKQTWRDNMGRAGEMELKPFSGEDYTCITFHPDLSKFKMQSLDKDIVALMV RRAYDIAGSTKDVKVFLNGNKLPIKGFRSYVDMYLKDKVDETGNALKIIHEQVNPRWEVC LTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVTKLVDVVKKKNKGGVAVKAHQVKNHM WIFVNALIENPTFDSQTKENMTLQVKSFGSTCPLSEKFIKAAIGCGIVESILNWVKFKAQ VQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSTECTLILTEGDSAKTLAVSGLGVVGRDK YGVFPLRGKMLNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMT DQDQDGSHIKGLLINFIHHNWPSLLHHRFLEEFITPIVKVSKNKQEVAFYSLPEFEEWKN STPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDD RKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVD GLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNN LNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLRFLYDDNQRVEPEW YIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLPMLPSYKNFKGTIE ELAPNQYVISGEMSILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREY HTDTTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILR DFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQR GYDSDPVKAWKEAQQKVPDEEENEESDNEKETAKSDSVTDSGPTFNYLLDMPLWYLTKEK KDELCKLRNEKEQELETLKRKSPSDLWKEDLAAFVEELEAVEAKEKQDEQIGLPGKGGKA KGKKTQRAEVLPSPCGKRVIPQVTIEMKAEAEKKIKKKIKNENTEGSSREDGIEIEGLKQ RLEKKQKREPGTKTKKQTTLPFKPVKKAKKRNPWSDSESDIDSNESNFDVPPREKEPRRA ATKTKFTMDLDSDEDFSDFDENTQDEDCVPSDASPPRTTTSPKHTNKELKPQKSATSVTD LNADDAKDNVPPPPSSPAADFPAVTKTTNPVPKKNVTVKKTAAKSQSSTSTTGAKKRAAP KGTKKDPDLDSDVSKKPNPPKTKSHRKRKPSTSDDSDSNFEKMISKAVTSKKPKEDSDDF HLDLDSAVASRAKSGRTKKPIKYLEESDEDDLF NT seq 4602 nt NT seq  +upstreamnt  +downstreamnt atggagatgtcaccgctgcagcctgtagatgacaatatgcaagtcaacaaaacaaagaaa aatgaagatgctaagaaaaggctgtctattgaaagaatctatcaaaagaaaacacaactg gaacatattctgctccgcccagacacctacattggctctgtggaatcagtgacccagcaa atgtgggtttacgatgaagatattggcattaactgtagggaagtcacttttgttcctggt ttgtacaaaatctttgatgagattctagtcaatgctgcagacaacaaacaaagggacccc aaaatgtcttgtattagagtcacaattgacccggagaataatttaattagtatatggaat aatggaaaaggtattcctgttgttgaacacaaagttgagaagatgtatgtcccagctctc atctttggacagctcctaacttctagtaactatgatgatgaagaaaagaaagtaacgggt ggtcgaaatggctatggagccaaattgtgtaacatattcagtaccaaatttactgtggaa acagccagtagagaatacaagaaaatgttcaaacagacatggagggataacatggggaga gctggtgagatggaactcaagccctttagtggagaagattatacatgtattaccttccac cctgatttgtctaagtttaaaatgcaaagcctagacaaagatattgttgcactgatggtt agaagagcatatgatattgctggatccactaaagatgtcaaggtctttctcaatggaaat aagcttccaataaaaggattccgtagctatgtagatatgtatctgaaggataaggtagat gaaactggcaatgcactgaaaattatccatgaacaagtaaaccccaggtgggaagtgtgt ttaacaatgagtgaaaaaggctttcagcaaatcagctttgtcaacagcattgctacttcc aagggtggcagacatgttgattatgtagctgatcagattgtgactaaacttgttgatgtt gtgaagaaaaagaacaagggtggtgttgcagtaaaagcacatcaggtaaaaaatcacatg tggatttttgtgaacgccttaattgaaaacccaaccttcgactcccagacaaaagagaac atgactttacaagtcaagagctttggatcaacgtgcccgttgagtgaaaaattcatcaaa gctgcaattggctgtggtattgtagaaagcatactaaactgggtgaaatttaaggcccaa gtccagttaaacaagaagtgttcagctgtaaaacataacagaatcaaaggaattcccaaa cttgatgatgccaatgatgcaggaggccgaaactccactgagtgtacacttatcctgaca gagggagactcagctaaaactttggctgtttcaggccttggtgtggttgggagagacaag tacggggttttccctcttagaggaaaaatgcttaatgttcgagaagcttctcataaacag ataatggaaaatgctgaaattaacaatataatcaagattgtgggtcttcagtacaagaaa aactatgaagatgaagattcattgaagactctgcgttatgggaagataatgattatgaca gatcaggaccaagacggttcccatatcaaaggcttgctgattaattttatccatcataac tggccctctcttctgcaccatcgttttctggaggaatttatcactcccattgtaaaggtg tctaaaaacaagcaagaagtagcattctatagccttcctgagtttgaagaatggaagaat tctacgccaaatcataaaaaatggaaagtcaagtattacaaaggtttgggcaccagcaca tcaaaagaagctaaagagtactttgcagatatgaaaagacatcgtatccaattcaaatat tcaggtcctgaagatgatgctgcaatcagcctggcctttagcaaaaaacagatagatgat cgaaaggaatggttaactcatttcatggaagatagaaggcaacgaaagttacttggcctt cctgaggattacttatatgggcaaactaccacatatctgacatataatgacttcataaat aaggaacttatcctgttctcaaattctgataatgagaggtctatcccatctatggtggat ggtttgaagccaggtcagagaaaggttttgtttacatgtttcaaacggaatgacaagcga gaggtgaaggttgcccagttagctgggtcagtagctgagatgtcctcttatcatcatggt gagatgtcactaatgatgaccattatcaatttggctcagaactttgtgggtagcaataat ctgaacctcttgcagcccattggtcagtttggtaccaggctgcatggtggcaaggattct gctagtcctcgatacatcttcacaatgctcagccctttggctcggttgttatttccacca aaagatgatcacacgttaaggtttttatatgatgacaaccaacgtgttgagcctgaatgg tacattcctattatacccatggtgctgataaatggcgctgaaggaattggtactgggtgg tcctgcaaaatccccaactttgatgttcgtgaagttgtgaataacatcagacgtttgatg gatggagaagaacctttgccaatgcttccaagttacaagaacttcaagggtactattgaa gagctggctccaaatcagtatgtgattagtggtgaaatgtctattcttaattctacaacc attgaaatctcagagcttcccatcagaacatggacccagacatataaagaacaggttcta gaacccatgttgaatggcactgagaagacaccccctctgataacagattatagggaatac cacacagacaccactgtgaagtttgttgtgaagatgactgaagaaaaactggcagaggca gagagagttggactacacaaagtcttcaaactccaaactagtctcacatgcaactctatg gtgctttttgaccatgtaggctgtttaaagaaatacgacacagtgttggatattctaaga gacttctttgaactcaggcttaaatattatggattaagaaaagaatggcttctaggaatg cttggcgctgaatctgctaaactgaataatcaggctcgctttatcttagagaaaatagat ggcaaaataatcattgaaaacaagcctaagaaagaattaattaaagttctgattcaaaga ggttatgattcggatcctgtgaaggcttggaaagaagcccagcaaaaggttccagatgaa gaagaaaatgaagagagtgacaatgaaaaggaaactgcaaagagtgactctgtaacagat tctggaccaaccttcaactaccttcttgatatgcctctttggtatctaaccaaggaaaag aaagatgaactgtgcaaactaagaaatgaaaaagagcaagagctagaaacattaaagaga aagagtccatcagatttgtggaaagaagacttggctgcttttgttgaagagctggaggct gttgaagcaaaggagaaacaagatgaacaaataggacttcctgggaaaggtgggaaagca aaggggaaaaaaacacaaagggcagaagttttgccttctccatgtggaaaaagagtcatc ccccaagtgaccatagagatgaaagcagaggcagaaaagaaaattaaaaaaaaaattaag aatgaaaatactgaaggaagctctcgagaggatgggatagaaatagaaggcctaaaacag agattggaaaagaaacagaaaagagaaccaggtaccaagacaaagaaacaaactacattg ccatttaaaccagtcaagaaagccaaaaagagaaacccctggtctgattcggaatcagat atagacagtaacgaaagtaattttgatgtccctccccgagaaaaagagccacggagagca gcaacaaaaaccaaattcacaatggatttggattcagatgaagatttctcagattttgat gaaaacactcaagatgaagattgtgtcccatcagatgctagtccacctaggaccacaact tccccaaaacatactaacaaagaactgaagccacagaaaagtgccacatcagtaacagac cttaacgctgatgatgccaaggataatgtaccacctcctccaagctctcctgctgctgat ttcccagctgtaactaaaaccacaaaccctgttcctaaaaagaacgtgacagttaagaag acggcagcaaaaagtcagtcttccacctctactacaggggccaaaaaaagggctgcacca aaaggaaccaaaaaggatccagacttggattctgatgtctctaaaaagcctaatcccccg aaaaccaagagtcaccgcaaaaggaagccgtccacttctgatgattccgactctaatttt gagaaaatgatttctaaagcagtcacaagcaagaaacccaaggaggacagcgatgacttc cacctggatttagactcagctgtggcttctcgggcaaaatcgggacggacaaagaaacct ataaagtacctggaagaatcagatgaagatgatctgttttaa

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