Orcinus orca (killer whale): 101270543
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Entry
101270543 CDS
T05247
Symbol
PLA2G4A
Name
(RefSeq) cytosolic phospholipase A2 isoform X1
KO
K16342
cytosolic phospholipase A2 [EC:
3.1.1.4
]
Organism
oor
Orcinus orca (killer whale)
Pathway
oor00564
Glycerophospholipid metabolism
oor00565
Ether lipid metabolism
oor00590
Arachidonic acid metabolism
oor00591
Linoleic acid metabolism
oor00592
alpha-Linolenic acid metabolism
oor01100
Metabolic pathways
oor04010
MAPK signaling pathway
oor04014
Ras signaling pathway
oor04072
Phospholipase D signaling pathway
oor04217
Necroptosis
oor04270
Vascular smooth muscle contraction
oor04370
VEGF signaling pathway
oor04611
Platelet activation
oor04664
Fc epsilon RI signaling pathway
oor04666
Fc gamma R-mediated phagocytosis
oor04724
Glutamatergic synapse
oor04726
Serotonergic synapse
oor04730
Long-term depression
oor04750
Inflammatory mediator regulation of TRP channels
oor04912
GnRH signaling pathway
oor04913
Ovarian steroidogenesis
oor04921
Oxytocin signaling pathway
oor05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09100 Metabolism
09103 Lipid metabolism
00564 Glycerophospholipid metabolism
101270543 (PLA2G4A)
00565 Ether lipid metabolism
101270543 (PLA2G4A)
00590 Arachidonic acid metabolism
101270543 (PLA2G4A)
00591 Linoleic acid metabolism
101270543 (PLA2G4A)
00592 alpha-Linolenic acid metabolism
101270543 (PLA2G4A)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101270543 (PLA2G4A)
04014 Ras signaling pathway
101270543 (PLA2G4A)
04370 VEGF signaling pathway
101270543 (PLA2G4A)
04072 Phospholipase D signaling pathway
101270543 (PLA2G4A)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
101270543 (PLA2G4A)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
101270543 (PLA2G4A)
04664 Fc epsilon RI signaling pathway
101270543 (PLA2G4A)
04666 Fc gamma R-mediated phagocytosis
101270543 (PLA2G4A)
09152 Endocrine system
04912 GnRH signaling pathway
101270543 (PLA2G4A)
04913 Ovarian steroidogenesis
101270543 (PLA2G4A)
04921 Oxytocin signaling pathway
101270543 (PLA2G4A)
09153 Circulatory system
04270 Vascular smooth muscle contraction
101270543 (PLA2G4A)
09156 Nervous system
04724 Glutamatergic synapse
101270543 (PLA2G4A)
04726 Serotonergic synapse
101270543 (PLA2G4A)
04730 Long-term depression
101270543 (PLA2G4A)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
101270543 (PLA2G4A)
09160 Human Diseases
09161 Cancer: overview
05231 Choline metabolism in cancer
101270543 (PLA2G4A)
Enzymes [BR:
oor01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.1 Carboxylic-ester hydrolases
3.1.1.4 phospholipase A2
101270543 (PLA2G4A)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PLA2_B
C2
cPLA2_C2
Motif
Other DBs
NCBI-GeneID:
101270543
NCBI-ProteinID:
XP_012390439
LinkDB
All DBs
Position
1:complement(44646676..44848532)
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AA seq
749 aa
AA seq
DB search
MSFIDPYQHIIVEHHYSHKFTVVVLRATKVTKGAFGDMLDTPDPYVELFISSTPDSRKRT
KHFNNDINPVWNETFEFILDPNQDNVLEITLMDANYVMDETLGTAIFPISSMKVGEKKEV
PFIFNQVTEMILEMSLEVCSSPDLRFSMALCDQEKAFRQQRKENIKENMKKLLGPKNNEG
LYSTRDVPVVAILGSGGGFRAMVGFSGVMKALYESGILDCATYIAGLSGSTWYMSTLYSH
PDFPEKGPEEINEELMKSVSHNPLLLLTPQKIKRYIESLWKKKSSGQPVTFTDIFGMLIG
ETLIHNRMNTTLSSLKEKVNTGQCPLPLFTCLHVKPDVSELMFADWVEFSPYEIGMAKYG
TFMAPDLFGSKFFMGTVVKKYEENPLHFLMGVWGSAFSILFNRVLGVSGSQSKGSTMEEE
LENITAKHIVSNDSSDSDDESQEPKGTENEEAEREYQNDNQASWVQRMIMALVSDSALFN
TREGRAGKVHNFMLGLNLNTSYPMSPLRDFTTQESLEEDELDAAVADPDEFERIYEPLDV
KSKKIHVVDSGLTFNLPYPLILRPQRGVDLVISFDFSARPSDSSPPFKELLLAEKWAKMN
KLPFPKIDPYVFDREGLKECYVFKPKNPDVEKDCPTIIHFVLANINFRKYKAPGVPRETK
EEKELADFDIFDDPESPFSTFNFQYPNQAFKRLHDLMYFNTLNNIDVIKNAIVESIEYRR
QNPSRCSVSLSSVEARRFFNKEFLSKPTA
NT seq
2250 nt
NT seq
+upstream
nt +downstream
nt
atgtcatttatagatccttatcagcacattatagtggagcaccattattcccacaagttc
acagtagtggtgttacgtgccacaaaagtaacaaagggggccttcggtgacatgcttgac
actccagacccctatgtggaacttttcatctcctcaacccctgacagcaggaagagaacg
aaacacttcaataatgacataaaccctgtgtggaatgagacctttgaatttattttggat
cctaatcaggacaatgttttggagatcacgttgatggatgccaattacgtcatggatgaa
acactcgggacagcaatatttcccatatcttctatgaaagtgggagagaagaaagaggtt
ccttttattttcaaccaagtcactgaaatgattctggaaatgtctcttgaagtttgttca
tccccagacctccgatttagtatggctctgtgtgaccaggagaaagctttccgacaacag
agaaaagaaaacataaaggaaaacatgaagaaactcctgggtccaaagaataatgaaggc
ttgtattctacacgtgatgtgcctgtggtggccatactgggctcaggtgggggtttccga
gccatggtaggattctccggtgtgatgaaggcattgtatgaatcaggaattttagattgc
gctacctacattgctggtctttctggatctacgtggtacatgtcaactttatattctcac
cctgattttccagagaaaggaccagaggagattaatgaagaactaatgaaaagtgttagc
cacaaccctcttttacttctcacaccacagaaaattaaaagatacattgagtctttatgg
aagaagaaaagctctggacaacctgtcacctttactgatatctttgggatgttaatagga
gaaacactaattcacaatagaatgaacactaccttgagtagtttgaaggaaaaagtcaat
actggacagtgccctttgcctcttttcacctgtctccatgtcaaacccgatgtctcagag
ctgatgtttgcagattgggttgaatttagtccatatgagattggcatggctaaatatggt
acttttatggctcctgacttatttggaagtaaattttttatgggaacagttgtaaagaag
tatgaagaaaaccccttgcatttcttaatgggtgtctgggggagtgccttttctatattg
ttcaacagagtcttgggagtttctggctctcaaagtaaaggttccacaatggaagaagaa
ctagaaaatattacagcaaagcatattgtgagtaatgatagctcggatagtgatgatgaa
tcacaagaacccaaaggcactgaaaatgaagaagcagaaagggaatatcaaaatgataat
caagcaagttgggtccaacgtatgataatggccttggtgagtgactcagctttgtttaat
accagagaaggacgagctgggaaggtgcacaacttcatgctgggcttgaatctcaataca
tcctatccgatgtctcctttgagagactttaccacccaggagtccttggaggaagatgaa
ttggatgcagctgtagcagatcctgatgaatttgagcggatatatgagcctctggatgtc
aaaagtaaaaagattcatgtggtggacagtggcctcacatttaacctgccgtaccccttg
atcctgagacctcaaagaggagttgatctcgtcatctcctttgacttttctgcaaggcca
agtgactccagtcctcccttcaaggaacttctgcttgcagaaaagtgggctaaaatgaat
aagctcccctttccaaagatcgatccttatgtgtttgatcgagaaggactgaaggaatgc
tatgtctttaaacccaagaatcctgatgttgagaaagattgcccaactatcatccatttt
gttctggccaacatcaacttcagaaagtacaaggctccaggtgttccaagagaaactaag
gaagagaaggaactagctgattttgatatttttgatgaccctgaatcaccattttcaacc
ttcaactttcaatacccaaatcaagcattcaaaaggctgcatgatctgatgtacttcaat
accctgaacaacatcgatgtaataaagaatgccatagttgaaagcattgaatatagaaga
cagaatccatctcgttgctctgtttccctcagtagtgttgaggcaagaagattcttcaac
aaggagtttctaagcaaacccacagcatag
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