Orcinus orca (killer whale): 101274058
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Entry
101274058 CDS
T05247
Symbol
NRG2
Name
(RefSeq) pro-neuregulin-2, membrane-bound isoform isoform X1
KO
K05456
neuregulin 2
Organism
oor
Orcinus orca (killer whale)
Pathway
oor01521
EGFR tyrosine kinase inhibitor resistance
oor04012
ErbB signaling pathway
oor05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
101274058 (NRG2)
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
101274058 (NRG2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101274058 (NRG2)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04052 Cytokines and neuropeptides [BR:
oor04052
]
101274058 (NRG2)
Cytokines and neuropeptides [BR:
oor04052
]
Cytokines
Growth factors (RTK binding)
101274058 (NRG2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Neuregulin
I-set
Ig_3
ig
Ig_2
Ig_6
C2-set_2
EGF
V-set
DUF3169
DUF6377
EGF_2
Motif
Other DBs
NCBI-GeneID:
101274058
NCBI-ProteinID:
XP_004280338
LinkDB
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Position
3:68532661..68711571
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AA seq
845 aa
AA seq
DB search
MRQVCCSALPPPPLEKARCSSYSDSSSSERSSSSSGGESSSSRSSSSDSNSGISRPAAPP
EPRPSQQPQPRSPAARRAAARSRAAAAGGMRRDPAPGFSMLLFGVSLACYSPSLKSVQDQ
AYKAPVVVEGKVQGLAPAGGSSSNSTREPPASGRVALVKVLDKWPLRSGGLQREQVISVG
SCAPLERNQRYIFFLEPTEQPLVFKTAFAPLDTNGKNLKKEVGKILCTDCATRPKLKKMK
SQTGQVGEKQSLKCEAAAGNPQPSYRWFKDGKELNRSRDIRIKYGNGRKNSRLQFNKVKV
EDAGEYVCEAENILGKDTVRGRLFVNSVSTTLSSWSGHARKCNETAKSYCVNGGVCYYIE
GINQLSCKCPVGYTGDRCQQFAMVNFSKHLGFELKEAEELYQKRVLTITGICVALLVVGI
VCVVAYCKTKKQRKQMHNHLRQNMCPAHQNRSLANGPSHPRLDPEEIQMADYISKNVPAT
DHVIRRETETTFSGSHSCSPSHHCSTATPTSSHRHESHTWSLEHSESLTSDSQSGIMLSS
VGTSKCNSPACVEARARRAAAYSLEEQRRAAVPPYHDSIDSLRDSPHSERYVSALTTPAR
LSPVDFHYSLATQVPTFEITSPNSAHAVSLPPAAPISYRLAEQQPLLRHPAPPGPGPGPG
TGADMQRSYDSYYYPAAGPGPRRGACALGGSLGSLPASPFRIPEDDEYETTQECAPPPPP
RPRARGASRRTSAGPRRWRRSRLNGLAAQRARAARDSLSLSSGSGGGSASASDDEADDAD
GALAAESTPFLGLRAAHDALRSDSPPLCPAADSRTYYSLDSHSTRASSRHSRGPPPRAKQ
DSGPL
NT seq
2538 nt
NT seq
+upstream
nt +downstream
nt
atgcggcaggtttgctgctcagcgctgccgccgccgccactggagaaggctcggtgcagc
agctacagcgacagcagcagcagcgagaggagcagcagcagcagcggcggcgagagcagc
agcagcaggagcagcagcagcgacagcaacagcggcatctctcgtcccgctgcgccccca
gagccgcggccgtcgcaacagccgcagccccgcagccccgcagcccggagagccgccgcc
cgctcgcgagccgcagccgccggcggcatgaggcgcgacccggcccccggcttctctatg
ctgctcttcggtgtgtcactcgcctgctactcgcctagcctcaagtcggtgcaggaccag
gcgtacaaggcacccgtggtggtggagggcaaggtacaggggctggccccggccggcggc
tccagctccaacagcacccgtgagccgcccgcctcgggtcgggtggcactggtgaaggtg
ctggacaagtggccgctccggagcgggggactgcagcgcgagcaggtgatcagcgtgggc
tcctgtgcgccgctcgaaaggaaccagcgctacatctttttcctggagcccacggagcag
cccttggtctttaagacagcctttgcccctcttgacaccaacggcaaaaacctcaagaaa
gaggtgggcaagatcctgtgcactgactgcgccacccggcccaagctgaagaagatgaag
agtcagacgggacaggtgggtgagaagcaatcactgaagtgtgaggcagcagctggtaac
ccccagccctcctaccgctggttcaaggatggcaaggagctcaaccgcagccgcgacatt
cgcatcaagtacggcaatggcagaaagaactcacgactacagttcaacaaggtgaaggtg
gaggacgctggggagtacgtctgcgaggctgagaacatcctggggaaggacaccgtcagg
ggccggctcttcgtcaacagcgtgagcactaccctatcatcctggtcggggcacgcccgc
aagtgcaacgagacagccaagtcctattgtgtcaacggaggcgtctgctactacatcgag
ggcatcaaccagctctcctgcaagtgtcctgtgggatacaccggggacaggtgtcagcag
ttcgcaatggtcaacttctccaagcaccttggatttgaactaaaggaagccgaggagctg
taccagaaaagggtcctgactatcaccggcatctgcgtggctctgctggtcgtgggcatc
gtctgcgtggtcgcctactgcaagaccaaaaaacagcggaagcagatgcataaccacctt
cgacagaacatgtgtccagcccaccagaaccggagcttggccaatgggcccagccacccc
cggctggaccctgaggagatccagatggcagactatatctccaagaatgtgccagccaca
gaccatgtcatccggagggaaacggagaccaccttctctgggagccactcctgttctcct
tctcaccactgctccacagccacgcccacctccagccacaggcatgagagccacacgtgg
agcctggaacattctgagagcctgacctccgactcccaatcgggcatcatgctgtcatca
gtgggcaccagcaagtgcaacagcccagcgtgtgtggaggcgcgggcacggcgggcggca
gcctacagcctagaggagcagcgcagggctgcggtgccaccttaccacgactccatagac
tccctgcgtgactccccacacagcgagaggtatgtgtcggccctgaccacgcccgcgcgc
ctctctcccgtggacttccattactcgctggccacgcaggtgccgactttcgagatcacg
tcccccaactcggcgcacgccgtgtcgctgccgccggccgcgcccatcagctaccgcctg
gcggagcagcagccgctcctgcggcacccggcgccccccggccccggtccagggcccggg
accggtgcggacatgcagcgcagctacgacagctactactaccccgcggcgggaccgggg
ccgcggcgcggggcctgcgccctaggcggcagcctgggcagtctgcccgccagccctttc
cgcatccccgaggacgacgagtacgagaccacgcaggagtgcgcgcccccgccgccgccg
cggccgcgcgcccgcggtgcgtcccgtaggacgtctgctggaccccggcgctggcgccgc
tcgcgcctcaacgggctggcggcgcagcgcgcacgcgcggcgcgggactcgctgtcgctg
agcagcggctcgggaggcggctcggcttctgcctcggacgacgaagcggacgacgcggac
ggggcgctggcggccgagagcacgcctttcctcggcctgcgtgcggcgcacgacgcgctg
cgctcggactcgccgccgctctgcccggcggccgacagcaggacttactactccctggac
agccacagcacgcgggccagcagcagacacagccgcgggccgcccccgcgggccaagcag
gactcggggcccctctag
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