Orcinus orca (killer whale): 101276321
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Entry
101276321 CDS
T05247
Symbol
ITGA2B
Name
(RefSeq) integrin alpha-IIb isoform X2
KO
K06476
integrin alpha 2B
Organism
oor
Orcinus orca (killer whale)
Pathway
oor04015
Rap1 signaling pathway
oor04151
PI3K-Akt signaling pathway
oor04510
Focal adhesion
oor04512
ECM-receptor interaction
oor04611
Platelet activation
oor04613
Neutrophil extracellular trap formation
oor04640
Hematopoietic cell lineage
oor04810
Regulation of actin cytoskeleton
oor04820
Cytoskeleton in muscle cells
oor05165
Human papillomavirus infection
oor05200
Pathways in cancer
oor05222
Small cell lung cancer
oor05410
Hypertrophic cardiomyopathy
oor05412
Arrhythmogenic right ventricular cardiomyopathy
oor05414
Dilated cardiomyopathy
oor05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
101276321 (ITGA2B)
04151 PI3K-Akt signaling pathway
101276321 (ITGA2B)
09133 Signaling molecules and interaction
04512 ECM-receptor interaction
101276321 (ITGA2B)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
101276321 (ITGA2B)
09142 Cell motility
04820 Cytoskeleton in muscle cells
101276321 (ITGA2B)
04810 Regulation of actin cytoskeleton
101276321 (ITGA2B)
09150 Organismal Systems
09151 Immune system
04640 Hematopoietic cell lineage
101276321 (ITGA2B)
04611 Platelet activation
101276321 (ITGA2B)
04613 Neutrophil extracellular trap formation
101276321 (ITGA2B)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101276321 (ITGA2B)
09162 Cancer: specific types
05222 Small cell lung cancer
101276321 (ITGA2B)
09172 Infectious disease: viral
05165 Human papillomavirus infection
101276321 (ITGA2B)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
101276321 (ITGA2B)
05410 Hypertrophic cardiomyopathy
101276321 (ITGA2B)
05412 Arrhythmogenic right ventricular cardiomyopathy
101276321 (ITGA2B)
05414 Dilated cardiomyopathy
101276321 (ITGA2B)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
oor01009
]
101276321 (ITGA2B)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
oor04147
]
101276321 (ITGA2B)
04515 Cell adhesion molecules [BR:
oor04515
]
101276321 (ITGA2B)
04090 CD molecules [BR:
oor04090
]
101276321 (ITGA2B)
Protein phosphatases and associated proteins [BR:
oor01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
101276321 (ITGA2B)
Exosome [BR:
oor04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
101276321 (ITGA2B)
Cell adhesion molecules [BR:
oor04515
]
Integrins
Integrin alpha subunits
101276321 (ITGA2B)
CD molecules [BR:
oor04090
]
Proteins
101276321 (ITGA2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Integrin_A_Ig_3
Integrin_A_Ig_2
Integrin_A_Ig_1
FG-GAP
FG-GAP_3
Integrin_alpha
ITGAX-like_Ig_3
Motif
Other DBs
NCBI-GeneID:
101276321
NCBI-ProteinID:
XP_004286027
LinkDB
All DBs
Position
19:39366073..39379946
Genome browser
AA seq
1034 aa
AA seq
DB search
MARALCPLHALWLLEWVQLLLGPGAAPPTWALNLDPVRLTFYTGPNGSYFGFSLDFYKDS
RGSVSIVVGAPRTLGRSQEETGGVFLCPWKAEGDQCTSLPFDLNDETRSAGTQTFQTFKA
RQGLGASVVSWSDIVVACAPWQHWNVLEKAEEAEKTPVGGCFVAQLQNSGRAEYSPCRAN
IMSRVYQKNYFSGDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLARAPLGDIISSYRP
GTLLWHVPTQQLTFDYSHPEYFDGYRGYSVAVGDFDGNPNTTEFVVGAPTWSWTLGAVEI
LSSYHQTLHRLHGEQMASYFGHSVAVTDVNRDGRHDLLVGAPLYMESRAGRKLAEVGRVY
LFLQTRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLNRDGYNDVAVAAPYGGASGRGQV
SVFLGQSEGLNSHPSQVLDSPFPTGSGFGFSLRGATDIDDNGYPDLLVGAYGANKVVVYR
AQPVVMATVQLLVQDSLNPAVKNCVLPLTETPVSCFNIQMCVGATGHNVPKKLHLNAELQ
LDRQKPRQGRRVLLLASQQASTVLGLDLSGRHGPTCHTTKAFLRDEADFRDKLSPIVLSL
NVSLQPEKDGLAPALMLHGDTHIQEQTRIILDCGEDDVCVPQLQLTASVTGSPLLIGADN
VLELQMEAANEGEGAYEAELAVHLPPGAHYMRALSNIEGFERIICNQKRENETKVVLCEL
GNPMKRNAQIGITMLVSVGNLEEAGEHVSFRLQIRSKNSQNPNSEMVMLDVPVRAEAHVE
LRGNSFPASLVVAAEESKRDNSSDSWGPKVEHTYELHNNGPGAVNGLRLNLRLPGQSQPS
DLLYILDIQPRGGLQCSPQPSPNPLKLDWGLPTSSPSQAYHKRDRRQALLPEQEQPSRLQ
GPVFVSCDSAPCTVVQCELQEMARGQRVMVTVLAFLSLPSLRKRPLDQFVLQSHAWFNVS
SLPYAVPALSLPSGEALVQTQLLRVLEERDIPIWWVLLGVLGGLLLLTFLVLAMWKVGFF
KRNRPPLQEDDEEE
NT seq
3105 nt
NT seq
+upstream
nt +downstream
nt
atggccagagctttgtgtccacttcatgccctctggcttctggagtgggtgcagctgctc
ttgggacccggtgctgcacctccaacctgggccttgaacctggacccggtgcgactcacc
ttctacacaggccccaatggcagctactttgggttttcattggacttctacaaggacagc
cgtgggagcgtgtccatcgtggtgggcgccccacggaccctgggccgcagccaggaggag
acaggcggcgttttcctgtgcccctggaaggccgagggcgaccagtgtacctcgctgccc
ttcgacctcaatgatgagacgcgaagcgcaggcacccaaactttccaaaccttcaaggcc
cgtcaaggactaggggcgtcggtcgttagttggagcgacatcgttgtggcctgcgccccc
tggcagcactggaacgtcctggaaaaggccgaggaggctgagaagacgcccgtaggtgga
tgcttcgtggctcagctgcagaacagcggccgcgcagagtactcaccctgccgggccaac
atcatgagccgagtttaccagaaaaattacttcagcggagacaagcgctactgtgaagcc
ggcttcagctctgtggtcactcaggctggggagctggtgcttggggcccctggcggctac
tatttcctaggtctcctggcgcgggctccacttggcgatatcatctcgagttaccgcccg
ggcaccctcttgtggcacgtgcccacccagcagctcacctttgactacagccacccagag
tacttcgacggctaccgggggtactcggtggctgtaggcgacttcgacgggaatccaaac
actacagagtttgtcgtcggtgcccctacctggagctggaccctgggagcggtggaaatt
ttgagctcgtaccaccagacgctgcaccggctgcatggagagcagatggcttcgtatttc
gggcactcagtggccgtcactgacgtcaacagggacgggaggcatgacctcttggtgggc
gcgccactgtacatggagagccgtgctggccgcaagctggccgaggtggggcgcgtgtac
ttgttcctgcagactcgaggccctcacgcgctgggcgcccccagcctcctgctgaccggc
acgcagctctatgggcgatttggctcagccatcgcgcctctgggcgacctcaaccgggat
ggctacaatgatgttgctgtggccgccccctatgggggtgccagcggtcgaggccaagtg
tcggtgttcctgggtcagagtgagggacttaactcacacccttcccaggtcctggacagc
cccttccccacaggctctggctttggcttctcccttcgaggtgccacagacatcgatgac
aatggatacccagacctgctggtgggagcttacggggccaacaaggttgttgtgtacagg
gctcagccggtggtgatggccactgtccagctgctggtgcaagattcgctgaatcctgct
gtgaagaattgtgtcctgcccctgaccgagacaccagtgagctgctttaacatccagatg
tgtgtgggagccactggacacaacgttcccaagaagctgcacctaaatgctgagctgcag
ctggaccggcagaagccccgccagggccggcgggtgctactgctggcctctcaacaggcg
agcacggtcctgggcctggatctgagcggaaggcacggccccacctgccacaccaccaag
gccttcctccgagatgaggccgacttccgggacaagctgagccccatcgtgctcagcctc
aatgtgtccctgcagcctgagaaggatggactagcccctgctctcatgttgcatggagac
acccacatccaggaacagacccgcatcattctggactgtggggaagatgacgtgtgtgtg
ccacagctccagctcactgccagcgtgacaggctccccgctcctcattggagctgataac
gtgctggagctgcagatggaagcggccaacgagggtgagggagcctacgaggccgagctg
gctgtgcacctgcctccaggcgcacactacatgcgggccctcagcaacatcgagggcttt
gagaggatcatctgtaaccagaagagggagaatgagaccaaggtggtgctgtgtgagctg
ggcaaccccatgaagaggaacgcccagataggaatcacgatgttagtgagtgtggggaac
ctggaagaggctggggagcacgtgtccttccggctgcagatcaggagcaagaacagccag
aatccaaacagtgagatggtgatgctggatgtgccagttcgggcagaggcccatgtggag
ctgagagggaactcctttccagcctccctggtggtggcagcagaagaaagcaagagagac
aacagctcggacagctggggccccaaagtggagcacacctacgagctccacaacaatggc
cctggtgctgtaaacggcctccgcctcaacctccgcctccccggccagtcccagccctcc
gaccttctctacatcctggatatacagccccggggaggccttcagtgctccccacaacca
tctcccaaccccctcaagctggactgggggctgcccacctccagcccttcccaggcctat
cacaagcgggaccgcagacaggcgctcctgccggagcaggagcagccctcgaggcttcaa
ggtccagtttttgtgagctgcgattcggcgccctgtactgtggtgcagtgtgagctgcag
gagatggcgcgcgggcagcgggtcatggtcacggtgctggccttcctgtcgctgcccagc
ctccgaaagaggcccctggatcagtttgtgctgcagtcgcacgcttggttcaacgtctcc
tcccttccctacgccgtgcccgccctcagcctgcccagcggggaagctctggtgcagaca
cagctgcttcgggtcttggaggagagagacattcccatctggtgggtgctgctaggcgtg
ctgggtggcctgctgttgctcacgttcctggtcctggccatgtggaaggttggcttcttc
aagcggaatcggccacccttacaagaagatgacgaagaggagtga
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