Orcinus orca (killer whale): 101276336 Help Entry 101276336         CDS       T05247                                  Symbol TSC2 Name (RefSeq) tuberin isoform X9   KO K07207   tuberous sclerosis 2 Organism oor  Orcinus orca (killer whale) Pathway oor04072   Phospholipase D signaling pathway oor04115   p53 signaling pathway oor04140   Autophagy - animal oor04150   mTOR signaling pathway oor04151   PI3K-Akt signaling pathway oor04152   AMPK signaling pathway oor04211   Longevity regulating pathway oor04218   Cellular senescence oor04714   Thermogenesis oor04910   Insulin signaling pathway oor04919   Thyroid hormone signaling pathway oor05163   Human cytomegalovirus infection oor05165   Human papillomavirus infection oor05168   Herpes simplex virus 1 infection oor05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:oor00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     101276336 (TSC2)    04151 PI3K-Akt signaling pathway     101276336 (TSC2)    04152 AMPK signaling pathway     101276336 (TSC2)    04150 mTOR signaling pathway     101276336 (TSC2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     101276336 (TSC2)   09143 Cell growth and death    04115 p53 signaling pathway     101276336 (TSC2)    04218 Cellular senescence     101276336 (TSC2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     101276336 (TSC2)    04919 Thyroid hormone signaling pathway     101276336 (TSC2)   09149 Aging    04211 Longevity regulating pathway     101276336 (TSC2)   09159 Environmental adaptation    04714 Thermogenesis     101276336 (TSC2)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     101276336 (TSC2)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     101276336 (TSC2)    05163 Human cytomegalovirus infection     101276336 (TSC2)    05165 Human papillomavirus infection     101276336 (TSC2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:oor01009]     101276336 (TSC2) Protein phosphatases and associated proteins [BR:oor01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      101276336 (TSC2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Tuberin DUF3384 Rap_GAP Cnd1 Motif Other DBs NCBI-GeneID:  101276336 NCBI-ProteinID:  XP_004270354 LinkDB All DBs Position 16:51150229..51187523 Genome browser AA seq 1748 aa AA seqDB search MAKPASKDSGLKEKFKILLGLGTPRPNPRSAEGKQTEFIITAEILRELSVECGLNNRIRV IGQICEVAKTKKFEEHAVEALWKAVSDLLQPERPPEARHAVLALLKAIVQGQGDRLGVLR ALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELAEFVLQWMDIGLSSEFLLVL VNLVKFNSCYLDEYIASMVHMICLLCVQTVSSVDIEVSLQVLDAVVCYNCLPAESLPLFI VTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCRIMEDRAYMEDAPLLRGAVFFVG MALWGAHRLYSLKNSPTSVLPSFYEAMTCPNEVVSYEIVLSITRLIKKYRRELQAVTWDI LLNIVERLLQQLQSLDSPELKAIVHDLLTTVEELCDQNEFHGSQERYFELIERCADQRPE SSLLNLITYRAQSIHPAKDGWIHNLQLLMERFFRNELRSAVRIKVLDVLSFVLLINRQFY EEELINSVVISQLSHVPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVIARSLS PPPELEERDVVVYSASLEDVKTAVLGLLVILQTKLYALPASHATRVYETLVSHIQLHYKH TYTLPIASSIRLQAFDFLLQLRADSLHRLGLPSKDGLVRFSPYCVCDYMEPERGSEKKAG GPLSPPTGPPGPAPAGPAVRLGSLPYSLLFRVLLQCLKQETDWKVLKLVLSKLPESLRYK VLIFTSPCSVDQLSAALCSMLSGPKTLERLRSTPEGFSRTDLHLAVVPVLTALISYHNYL DKTRQREMVYCLEQGLIYRCASQCVVALAICSVEMPDIIIKALPVLVVKLTHISATASMA IPLLEFLSTLARLPQLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRC RLPFRKDFVPYITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKRIQTSLTSASLGSAD ENSMAQADDNLKTLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGN KLVTVTTSVGTGTRSLLGLDSGELQGGPELSSDPSVHVRQTKEAPAKLESQAGQQVCRGA RDRVRSMSGGHGLRVGALDAPASHFPGSPASPGLQTAPASKPEKASASTQLPAQKEKTNL AAYVPLLTQGWAEILVRRPTGNTSWLMSLENPLSPFSSDINNTPLQELSNALMAAERFKE RRDTALYKSLSVPAAGSAKPPPPPRSNTDSAVVLEEGSPGEASLPVEPPELEDFEATLGT DGRYRHAEAFSRSSSTSSQEEKSFHAEELAAGGIPIERAISSEGSRPSVELAFQPSQPLS KSSSSPELQTLQDILGDPGDKADVGRLSPEAKARSQSGILDREGAAWSAPGEESQGQGPT QPEGPLPSSCPRSPSGLRPRGYTISDSAPSRRGKRVERDAFKSRAGTSNTEKVPGINPSF VFLQLYHSPFFGDESNKPILLPNESFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAI LSNEHGSYRYTEFLTGLGKLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHI ATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIITPLDYECN LVSLQCRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDTYPSKWI ARLRHIKRLRHRIREEAHYSNASLPLMQTHPPGHAKAPTQAPAESTPTYETGQRKRLVSS VDDFTEFV NT seq 5247 nt NT seq  +upstreamnt  +downstreamnt atggccaagccagcaagcaaagattcaggcttgaaggagaagttcaagattctattggga ctgggaactccaaggccaaatcccaggtctgcagagggcaaacagacggagtttatcatc acggcggaaatcctgagagagctgagtgttgaatgtggcctcaacaatcgcatccgggtg atagggcagatctgtgaggttgccaaaacgaagaaatttgaagagcatgcggtggaagca ctctggaaggccgtctcggacttgctgcagccagagcggccgccagaggcccggcacgcc gtgctggctctgctgaaggccatcgtgcaggggcagggagaccgcttgggcgttctcagg gccctcttctttaaggtcatcaaggattacccctctaacgaagacctccacgagagactg gaagttttcaaggccctcacggacaacgggagacacatcacctacttggaggaagagctg gctgaatttgtcctgcagtggatggacattggcctgtcctcagaattccttctggtgctt gtgaatttggtcaaattcaacagctgttacctcgatgaatacattgcatccatggtccac atgatctgcctgctgtgcgtccagaccgtgtcctccgtggacatagaggtctctctgcag gtgctggacgccgtggtctgctacaactgcctgccggccgagagcctccccctgttcatc gtcaccctctgccgcaccatcaatgtcaaggagctctgtgagccttgctggaagctgatg cgcaatctcctgggcacccacctgggccacagtgccatctacaatatgtgccgcatcatg gaggacagagcctacatggaagatgccccactgctgagaggagctgtgttctttgttggc atggctctctggggagcccaccggctctactctctcaagaactccccaacatctgtgttg ccgtcattttatgaggccatgacctgtccgaacgaggtggtgtcctatgagatcgtgctc tccataaccagacttatcaagaagtaccggagggagctccaggctgtgacatgggacatc ctgctgaacattgttgaacgcctgcttcagcagctccagagcctggacagcccagaactc aaagctatcgtccacgacctgctgaccacggtggaagagctgtgtgatcaaaatgagttc catggctcgcaggagagatactttgagctcattgagagatgtgcagaccagaggcctgag tcctccctcttaaacttaataacctacagggctcagtcaatccatccagcaaaggatggc tggattcacaacctgcagttactgatggagagatttttcagaaacgaattgcgcagtgct gtgcgtatcaaggtgctggacgtcctgtccttcgtgctgctcatcaacaggcagttctat gaggaggagctgatcaactcagtggtcatctcacagctctcccacgtcccggaggataaa gaccaccaagtccgaaagctggccacccagttgctggtagatctggctgaaggctgccac acccaccactttaatagcctgctggacatcattgagaaagtgattgcccgctccctgtct ccaccccctgagctggaggaaagggatgtggtggtgtactcggcctccttggaggatgtg aagactgcagtcctgggactcctggtcatccttcagaccaagctgtacgccctgcctgcc agccacgccacacgtgtgtatgaaacgcttgtcagccatatccagctccactacaagcac acctacaccctgcccattgccagcagcatccggctgcaggctttcgacttcctcctgcag ctgcgggccgactcgctgcaccgcttgggcctgcccagcaaggacgggcttgtgaggttc agcccctactgcgtctgcgactacatggagccggagaggggctctgagaagaaggctggt ggccccctgtcacctcccactgggccccctggcccggcacctgcaggccccgccgtgcgg ctcggctcgctgccctactccttgctcttccgtgtcctgctgcagtgtttgaagcaggag actgactggaaggtgctgaagctggtgctcagcaagctgcccgagtctctgcgctacaag gtcctcatcttcacctccccgtgtagtgttgaccagctatctgccgccctctgctccatg ctttcaggtcccaagaccctcgagcggctccgaagcaccccagaagggttctccagaacc gacctgcatctcgctgtggttcccgtgctgacagcgttaatttcttatcataactacttg gacaaaaccagacagcgggagatggtgtactgcctggagcaaggcctcatctaccgctgc gccagccagtgcgtggtggccctggccatctgcagcgtggagatgcctgacatcatcatc aaggcgctgcctgtcctggtcgtgaagctcacgcacatctcagccacggccagcatggcc attccactcctcgagttcctgtcgactctggccaggctacctcagctctacaggaacttt gcagcagagcagtacgccagtgtgtttgctatctccctgccgtataccaacccctccaag ttcaatcagtacattgtgtgcctggcccatcacgtcatagccatgtggttcattaggtgc cgcctgcccttccggaaagattttgttccttatatcactaagggtctgcgctccaacgtt ctcctgtcttttgatgacacccccgaaaaggacagctttagagcacggagcaccagtctc aacgagaggcccaagaggatccagacatctctcacgagcgccagcttggggtctgcagat gagaactcaatggcccaggctgacgacaacttgaaaactctccacctggagctcacagag acgtgtctggacatgatggccagatacgtgttctccaacttcacggcggtccccaagagg tcccccgtgggagagttcctcctggcaggtggcaggacgaaaacctggctggttgggaac aagcttgtcaccgtgacgacgagcgtgggaactgggacccggtctctgctgggcctggac tcaggagagctgcaggggggcccagagttgagctctgaccccagtgtgcacgtgagacag acaaaggaggcaccagccaagctggagtcccaggctgggcaacaggtgtgccgtggagcc cgggaccgggtccgctccatgtctgggggccatggccttcgagttggtgccttggatgct ccagcctcccactttcctggcagccctgcttccccgggcttacagactgctccagccagc aagcccgagaaagcctcagccagcacccagctaccggcacagaaggagaagacaaacctg gcggcttacgtccccctgctgacccagggctgggcagagatcttggtccggagacccaca gggaacaccagctggctgatgagcctggagaacccactcagtcccttctcctcggacatc aacaacacgcccctgcaggagctgtccaatgccctaatggccgccgagcgcttcaaggag cgtcgcgacacggccctctacaagtcgctgtcggtgccagcggccggctcagccaagccc cccccacccccacgctctaacacagactctgcagtagttctggaggagggaagtccaggc gaggctagtttgccagtggagccccccgaactggaagactttgaggcaaccctaggcaca gacgggcgctatcggcacgctgaagctttcagcaggtcatcttcgacctccagccaggag gagaagtcattccacgccgaggagttggctgctggggggatccccatcgagcgggccatc tcctctgagggctcccggccctctgtggagctcgccttccagccctcgcagcccctgagc aagtcaagctcatcgcctgaactacagacgctgcaggacatccttggggaccctggggac aaggctgatgtcggccggctgagccctgaggccaaggcccggtcacagtcagggatcctg gacagggaaggtgctgcctggtcagccccaggcgaagagagccagggccagggtcccacc cagcctgagggtcccttgccttccagctgtccccgctcccccagtgggctgcggcctcga ggctacactatctctgattcggccccgtcacgcaggggcaagagggtggagagggacgcc ttcaagagcagagctgggacctccaataccgagaaggtgccgggtatcaaccctagcttt gtgttcctgcagctctaccactcacctttcttcggtgatgagtccaacaagccaatcctt ttacccaatgagtcttttgagcggtcagtgcagctccttgaccagatcccatcgtatgac acacacaagatcgccgtcctgtacgtgggagaaggccagagcaacagtgagctcgccatc ctgtccaatgagcatggctcctacaggtacacagaattcctgacggggctgggcaagctc atcgagctcaaggactgccagccggacaaggtgtacctgggcggcctggacgtgtgcggc gaggacggccagttcacctactgctggcatgacgacatcatgcaagccgtcttccacatc gccaccctgatgcccaccaaggacgtggacaagcatcgctgtgacaagaagcgccacctg ggcaacgacttcgtgtccattgtctacaatgactctggcgaggacttcaagctcggcacc atcaaaggccagttcaactttgtccacgtgatcatcactcccctggattatgagtgcaac ctggtgtcgctgcagtgcaggaaagacatggagggcctcgtggacaccagcgtggccaag atcgtgtctgaccgaaacctgcccttcgtggcccgtcagatggccctgcacgcaaatatg gcctcgcaggtgcaccacagccgctccaaccccaccgacacctatccctccaagtggatt gccaggctccgccacatcaagcggctccgccaccggatccgtgaggaagcccactactca aacgccagcctgcccctgatgcagactcaccctcctggccacgccaaggcccccacgcag gccccagctgagtccacgcccacctacgagacaggccagcggaagcgcctcgtctcctcc gtggatgacttcactgagtttgtgtga

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