Orcinus orca (killer whale): 101276513
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Entry
101276513 CDS
T05247
Symbol
GNE
Name
(RefSeq) bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase isoform X3
KO
K12409
bifunctional UDP-N-acetylglucosamine 2-epimerase / N-acetylmannosamine kinase [EC:
3.2.1.183
2.7.1.60
]
Organism
oor
Orcinus orca (killer whale)
Pathway
oor00520
Amino sugar and nucleotide sugar metabolism
oor00541
Biosynthesis of various nucleotide sugars
oor01100
Metabolic pathways
oor01250
Biosynthesis of nucleotide sugars
Module
oor_M00955
CMP-Neu5Ac/Neu5Gc biosynthesis, animals, UDP-GlcNAc => CMP-Neu5Ac => CMP-Neu5Gc
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00520 Amino sugar and nucleotide sugar metabolism
101276513 (GNE)
00541 Biosynthesis of various nucleotide sugars
101276513 (GNE)
Enzymes [BR:
oor01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.60 N-acylmannosamine kinase
101276513 (GNE)
3. Hydrolases
3.2 Glycosylases
3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
3.2.1.183 UDP-N-acetylglucosamine 2-epimerase (hydrolysing)
101276513 (GNE)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Epimerase_2
ROK
Hexokinase_1
FGGY_N
DRTGG
Glucokinase
Motif
Other DBs
NCBI-GeneID:
101276513
NCBI-ProteinID:
XP_004271480
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Position
6:complement(84477926..84518489)
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AA seq
722 aa
AA seq
DB search
MEKKENNRKLRVCVATCNRADYSKLAPIMFGIKMEPEFFELDVVVLGSHLIDDYGNTYRM
IEQDDFDINTRLHTIVRGEDEAAMVESVGLALVKLPDVLNRLKPDIMIVHGDRFDALALA
TSAALMNIRILHIEGGEVSGTIDDSIRHAITKLAHYHVCCTRSAEQHLISMCEDHDRILL
AGCPSYDKLLSAKNKDYMSIIRMWLGDDVKSKDYIVALQHPVTTDIKHSLKMFELTLDAL
ISFNKRTLVLFPNIDAGSKEMVRVMRKKGIEHHPNFRAVKHVPFDQFIQLVAHAGCMIGN
SSCGVREVGAFGTPVINLGTRQIGRETGENVLHVRDADTQDKILQALHLQFGKQYPCSKI
YGDGNAVPRILKFLKSIDLQEPLQKKFCFPPVKDNISQDIDHILETLSALAVDLGGTNLR
VAIVSMKGEIVKKYTQFNPKTYEERINLILQMCVEAAAEAVKLNCRILGVGISTGGRVNP
REGIVLHSTKLIQEWNSVDLRTPLSDTLHLPVWVDNDGNCAALAERKFGQGKGLENFVTL
ITGTGIGGGIIHQHELIHGSSFCAAELGHIVVSLDGPDCSCGSHGCIEAYASGMALQREA
KKLHDEDQLLVEGMSVPKDEAVGALHLIQAAKLGNAKAQSILRTAGTALGLAVVNILHTM
NPSLVILSGVLASHYIHTVKDVIRQQALSSVQDVDVVVSDLVEPALLGAASMVLDYTTRR
IY
NT seq
2169 nt
NT seq
+upstream
nt +downstream
nt
atggagaagaaggagaataaccgaaagcttcgggtttgtgttgctacttgcaaccgtgct
gattattctaaactcgccccaatcatgtttggcattaaaatggaacctgagttctttgaa
cttgacgtggtggtacttggctctcacctgatagatgactatggaaacacatatcgcatg
attgaacaagatgactttgacattaacaccagactacacacaattgtcagaggggaagat
gaggcagccatggtggagtcagtgggcctggcccttgtgaagctaccagatgttcttaac
cgcctgaagcctgatatcatgattgttcatggagacaggtttgatgccctggctctggct
acgtctgctgccttgatgaacatccgaatccttcacattgaagggggggaagtcagtggg
accattgacgactctatcagacacgctataacgaaactggctcattatcatgtgtgctgc
acccgaagtgcagagcaacacctgatatccatgtgtgaggaccatgatcgcatcttgttg
gcaggctgcccttcctatgacaaacttctctccgccaagaacaaagactacatgagcatc
attcggatgtggttaggtgatgatgtaaaatctaaagattacattgttgcactacagcac
cctgtgaccacggacattaagcattccctaaaaatgtttgaactaacattggatgcactt
atctcatttaacaagcggaccctagttctgtttccaaatattgatgcagggagcaaagaa
atggttcgagtgatgcggaagaagggcattgagcatcatcccaattttcgtgcagttaaa
catgtcccatttgaccagtttatacagctggttgcccatgctggttgtatgattgggaac
agcagctgtggggtacgagaggttggagcttttggaacacctgtgatcaacctaggaaca
cgtcagattggaagagaaacaggggagaatgtccttcatgtccgggatgctgatacccaa
gacaaaatattgcaagcgctgcaccttcagtttggtaaacagtacccttgttcaaagata
tatggggatggaaatgctgttccgaggattttgaagtttctcaaatctattgatcttcaa
gagccactacaaaagaaattctgttttcctcctgtgaaggataacatctcccaagatatt
gaccatattcttgaaactctaagtgccttggctgttgatcttggtgggacgaacctccga
gttgcaatagtcagcatgaagggtgaaatagttaagaagtatactcagttcaatcctaaa
acctatgaagagaggattaatttaatcctacagatgtgtgtagaagctgcagcagaagct
gtaaaactgaactgcagaattttgggagtaggcatttccacaggtggccgtgtaaatcct
cgggaaggaattgtgctgcattcaaccaaactgattcaagagtggaactctgtggatctc
aggacccccctgtctgacactttgcatctccccgtatgggtagacaatgatggcaactgt
gctgcccttgcagaaaggaaatttggccaaggaaagggccttgaaaactttgtgacactt
atcacaggcacaggaattggcggggggatcatccatcagcatgaactgatccatggcagc
tccttctgcgctgcagagcttggccacattgtggtgtccctggatgggcctgactgttcc
tgtggaagccatgggtgtattgaagcatatgcctctggaatggccttgcagagggaagca
aaaaagctacatgatgaagaccagctcttggtggaagggatgtcagtgccaaaagatgaa
gctgtgggcgcactccatctcatccaagctgcgaaacttggcaatgcaaaggcccagagc
atcttgagaacagctggaacagcgttgggtcttgcggttgtgaacatcctccacactatg
aatccttcccttgtgatcctctctggagtcctagccagtcactatatccacactgtcaaa
gacgtcatccgccagcaagccttgtcctcggttcaggacgtggacgtggtggtttcggat
ttggtggaacccgccctgctcggcgcggccagcatggttctggactacacgactcgcagg
atctactag
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