Orcinus orca (killer whale): 101277661
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Entry
101277661 CDS
T05247
Symbol
SLC46A1
Name
(RefSeq) proton-coupled folate transporter
KO
K14613
MFS transporter, PCFT/HCP family, solute carrier family 46 (folate transporter), member 1
Organism
oor
Orcinus orca (killer whale)
Pathway
oor01523
Antifolate resistance
oor04977
Vitamin digestion and absorption
oor04978
Mineral absorption
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09150 Organismal Systems
09154 Digestive system
04977 Vitamin digestion and absorption
101277661 (SLC46A1)
04978 Mineral absorption
101277661 (SLC46A1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
101277661 (SLC46A1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
oor02000
]
101277661 (SLC46A1)
Transporters [BR:
oor02000
]
Solute carrier family (SLC)
SLC46: Folate transporter
101277661 (SLC46A1)
Major facilitator superfamily (MFS)
Organic acid transporters
Proton coupled folate transporter/heme carrier protein (PCFT/HCP) family [TC:
2.A.1.50
]
101277661 (SLC46A1)
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Gene cluster
GFIT
Motif
Pfam:
MFS_1
Sugar_tr
Motif
Other DBs
NCBI-GeneID:
101277661
NCBI-ProteinID:
XP_004267186
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Position
19:complement(4844067..4852749)
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AA seq
459 aa
AA seq
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MEGRANSRGESRAWPAGPVLCRGCVEPLIFLANFALVLQGPVTTQYLWHRFSADLGYNGT
RDRGSCTNHSVDPTAQKVETLTSHWTLYMNMGGFLVGLFSSTLLGAWSDCVGRRPLLVLA
SLGLLLQTVLSIFVVQLQLHVGYFVLGRILCALLGDFSGLLAAGFASVADVSSSRTRSIR
MALLEACIGVAGMLASLIGGNWLQEQGYANPFWLALAVLIAMTLYAAFCFGETVKEATPA
RLFTLRHHRSIVQLYVTQAPEKSRKHLALYSLTIFVVITVHLGAQDILTLYELSTPLCWD
SRLIGYGSAAQHLPYLTSLLGLRLLQYCLADTWVAEIGLAFNIMGMVVFAFATITPLMFT
GYGLLFLSLVVTPVIRAKLSRLVRESEQGALFSAVACVNGLAMLTASGIFNSLYPATLNF
MKGFPFLLGAGLLFIPAVLIGILERANHCPEFQQFSQSP
NT seq
1380 nt
NT seq
+upstream
nt +downstream
nt
atggagggacgcgcgaattcccggggcgagtcccgcgcctggcccgccgggcccgtgctg
tgccgcggctgcgtggagcctctcatcttccttgccaacttcgccttggtcctgcagggc
ccggtcaccacgcagtacctgtggcaccgcttcagtgccgaccttggctacaacggcact
cgtgacaggggcagctgcaccaaccatagcgtggaccccaccgcgcagaaagtggagacg
cttacctcccactggaccctctacatgaacatgggcggcttcctggtgggactcttctcg
tccaccctgctgggtgcctggagtgactgtgtgggccgccgcccgctgctggtgctggcc
tccctcggcctgctgctccagaccgtgctgtccatctttgtggtacagctgcagctccac
gttggctacttcgtgctgggccgcatcctttgtgccctcctcggcgatttcagcggcctc
ctggctgctggctttgcctccgtggcagatgtcagctccagccgcacccgttccatccga
atggccctgctggaagcgtgcatcggggtggcagggatgctggcgagtctcattggtggc
aactggctccaggagcagggttatgccaaccctttctggttggccttggccgtgctgatt
gccatgactctctatgcagcattctgctttggtgaaacagtgaaagaggcgacacccgcc
cggctcttcacactccgtcaccaccgatccatcgtccagctctatgtgacccaggccccg
gagaagtccaggaagcacttagccctgtactcgttgaccatcttcgtggtgatcactgtg
caccttggggcccaggacatcctgaccctctatgagctgagcacacccctctgctgggac
tctaggctgattggctacggttctgcggctcagcacctcccatacctcaccagcctgctg
ggcctgcggcttctgcagtactgcctggccgacacctgggtggctgagatcggtctggcc
ttcaacatcatggggatggtggtctttgcatttgctaccattacacccctcatgttcaca
gggtacgggctcctcttcctgtcgttggtcgtcacgcctgtcatccgggccaaactctcc
aggctggtgagagagtcagagcagggtgctctcttttctgctgtggcctgtgtgaatggc
ttggccatgctgacagcctccggcatcttcaactcgctctacccagccaccctgaacttc
atgaagggcttccctttcctcctgggagctggcctcctcttcatcccggccgtcctgatt
gggatactggaaagggctaatcattgccctgaattccagcagttttcccagagcccctga
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