Orcinus orca (killer whale): 101279035
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Entry
101279035 CDS
T05247
Symbol
PFAS
Name
(RefSeq) phosphoribosylformylglycinamidine synthase isoform X1
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
oor
Orcinus orca (killer whale)
Pathway
oor00230
Purine metabolism
oor01100
Metabolic pathways
Module
oor_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
101279035 (PFAS)
Enzymes [BR:
oor01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
101279035 (PFAS)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
AIRS
Motif
Other DBs
NCBI-GeneID:
101279035
NCBI-ProteinID:
XP_004266915
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All DBs
Position
19:12509735..12528508
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AA seq
1338 aa
AA seq
DB search
MSSVLHFYVRPSGHERAASEYTQRKLQGELPELQGVKTELCYNVNWTAESSPSAEEMKKL
TWLFGCPLLLDDVAQESWLLPGPTDLLLEVGPRLNFSTPTSSNIVSVCQAVGLGAVDRVE
PTRRYLLSFAHPPSAELEAVALATLHDRMTEQHFPRPIQSFSLGCTPAPLGGPIDILAEG
RSALEKANQELGLALDSWDLDFYTKRFQELQRNPSTVEAFDLAQSNSEHSRHWFFKGRLH
VDGQELAHSLFESIMSTQASSHPNNVLKFCDNSSAIQGKEVQFLRPEDPSRPSCFRQRQG
LRHVVFTAETHNFPTGVAPFSGATTGTGGRIRDVQCTGRGAHVVAGTAGYCFGNLHIPGY
SMPWEDPSFQYPGNFARPLEIAIEASNGASDYGNKFGEPVLAGFARSLGLQLPDGQRREW
IKPIMFSGGIGCIEAEHVSKEPPEPGMDVVKVGGPVYRIGVGGGAASSVQVQGDNASDLD
FGAVQRGDPEMEQKMNRVIRACVEAPGGNPICSLHDQGAGGNGNVLKELSDPAGAVIYTS
RFQLGDPTLNALEIWGAEYQESNALLLRPPDRDFLSRVSARERCPVCFVGTITGDGRIVL
VDDRECPMGRDGQGDAPPTPPPTPVDLDLDWVLGKMPRKEFFLQRSLPVLRPLALPPGLS
VRQALAWVLRLPAVASKRYLTSKVDRSVGGLVAQQQCVGPLQTPLADVAVVALSHQELVG
AATALGEQPVKSLLDPKVAARLAVAEALTNLVFALVTDLRDVKCSGNWMWAAKLPGEGAA
LADACGAVAAVMAALGVAVDGGKDSLSMAARVGAETVRAPGSLVISAYAVCPDITATVTP
DLKCPGGRGHLLYVPLSPGRHRLGGTALAQCFSQLGEQPPDLDLPENLVQAFGITQGLLK
DRLLCSGHDVSDGGLITCLLEMAFAGNCGIEVAIPAPGVNALPVLFAEEPGLVLEVQEPD
LAQVLTRYREAGLHCLELGRTGSAGPHATVRVSVNGAVVLEEPVGQLRALWEETSFQLDR
LQAEPHCVAQEEGGLRERTGPTYCLPPTFPTASVPHEPGGPAPRVAIFREEGSNGDREMA
DAFHLAGFEVWDVTMQDLCSGAVRLDTFQGMAFVGGFSYADVLGSAKGWAAAVTFNPQAG
AELRRFRQRPDTFSLGVCNGCQLLALLGWVGGSPGDEAAEMGHESWPARPGLLLRHNQSG
RFESRWASVRVGPGPALMLRGMEGAVLPVWSAHGEGYMAFSSPELQAQIEARGLAPLHWA
DDDGNPTEQYPLNPNGSPGGMAGICSPDGRHLALMPHPERSVRPWQWAWRPPPFDTMTTS
PWLQLFINARNWTREGGC
NT seq
4017 nt
NT seq
+upstream
nt +downstream
nt
atgtcctcagtccttcacttctatgtccgtccctctggccacgagagggcagcctctgaa
tatactcaaaggaagctgcaaggggaactgccagagctgcagggtgtcaagaccgagctg
tgctacaatgtgaactggacagctgagtcctccccgagcgccgaggagatgaagaagctg
acgtggctgtttggctgccccttgttactggacgatgtcgctcaggagtcctggctcctt
cccggccccactgacctgctgctggaggtcgggcccaggctgaacttctccacgccaaca
tccagcaacatcgtgtcagtgtgccaggctgtggggctgggggccgtggaccgcgtggag
ccgacccggcgctacctgctctcgtttgcccacccgccttcggctgagctagaggccgtc
gccctggctaccctgcatgaccggatgacggagcagcacttcccccgtcccatccagagc
ttctccctggggtgcaccccagcaccccttggcggcccaattgacatactggccgagggc
cggtctgccctggagaaagccaaccaggagctaggtctggccctagactcctgggacctg
gatttctacaccaagcgcttccaggagctgcagcggaaccccagcactgtggaggccttc
gacttggctcagtccaatagtgagcacagccgacactggttcttcaagggccgactccac
gtggatgggcaggagctggcacactcgctgtttgagtccatcatgagcacccaggcatcc
tcgcaccccaacaacgtcctcaagttctgtgacaacagcagtgcaatccaggggaaggaa
gtccaattcctgcgtcccgaggacccctcacggccaagctgcttccggcaacgtcagggg
ctgagacatgtcgtcttcacggcagagacccacaacttccccacgggagtagcccccttc
agcggtgcgaccactggcacagggggccggatccgagatgtccagtgcacaggccgcggg
gcccacgtggtggctggcactgctggctattgctttggaaacctgcacatcccaggttac
agtatgccctgggaggatccaagcttccagtatcctgggaactttgcccgacccctggag
attgccatcgaggccagtaatggggcttctgactacggcaacaagtttggagaaccagtt
ctggctggctttgcccgttccttgggcctccagctcccagatggccagcggcgcgagtgg
atcaagcccatcatgtttagtggaggcattgggtgcatagaagctgagcatgtgagcaag
gagcccccagagccaggcatggatgttgtgaaggttgggggtcctgtctacaggattgga
gtcgggggcggagctgcttcgtccgtgcaggtgcagggagacaacgccagcgacctggac
ttcggggctgtgcagcggggagacccggagatggaacagaagatgaaccgtgtgatccgg
gcttgcgtggaggcccccggaggaaaccccatctgcagccttcatgaccagggtgccggt
ggcaatggcaacgtcctgaaggagctgagtgacccagctggagccgtcatttataccagc
cgcttccagctcggggacccgaccctgaacgccctggaaatctggggggctgagtaccag
gagtcaaatgcacttctgctgaggccccccgaccgggacttcctgagtcgtgtcagtgcc
cgggaacgctgcccagtttgctttgtgggcaccatcacgggagacgggaggatagtgctg
gtggatgatcgggagtgtcctatgggaagagatggccagggggatgcccccccaacacct
cccccgacacctgtggacctggatctggactgggtgctgggcaagatgccccggaaggag
ttcttcctccagaggagtctccccgtgctgcggcccctggccttgcccccagggctgagc
gtgcgccaggccctggcatgggtcctcaggctgcctgcggtggccagcaagcgctacctc
accagcaaggtggaccgctccgtgggcggcctggtggcacagcagcagtgtgtgggaccc
ctgcagacccctctggcagatgtggcggtggtggcactgagtcaccaggagctcgtaggg
gctgccacagccctgggagagcagcccgtcaagagcctgctagaccccaaggttgctgcc
cggctggctgtggctgaagccctcaccaacctggtgtttgctctggtcaccgacctccgg
gacgtgaaatgcagcgggaactggatgtgggcggccaagctcccgggggagggtgcggct
ctggccgacgcctgtggggctgtggcagccgtgatggcggccctgggtgtggcagtggat
ggtggcaaggactccctcagcatggctgcccgggttggcgctgagaccgtgcgggctcct
gggtcgctggtcatctcagcctatgctgtctgtccagacattacagccactgtgacccca
gacctcaagtgtcccggagggagaggccacctgctctacgtgcctctgagtcctgggcgc
catcggctcgggggcacagctctggcccagtgcttctcccagctcggcgagcagcctccc
gatctggaccttcccgagaacttggtgcaagccttcggcatcacccaggggctgctgaaa
gaccgcctcctctgctcaggccacgatgtcagtgacggaggtctcatcacctgcctgcta
gagatggcctttgctgggaattgtgggatagaggtggccatccctgcccctggggtcaat
gcgctgcctgtactgttcgctgaggagccaggcttggtgctggaggtgcaagagccagac
ctggcccaagtactgacacgttaccgggaggctggcctccactgcctggagctgggccgc
acgggcagcgccgggccccatgccacggtccgggtatcagtgaacggggctgtcgttctg
gaggagcccgttgggcagctacgagccctctgggaggagaccagtttccagctggatcgg
ctgcaggcagagccccactgtgtggcccaggaagaaggagggctgagggagcggacgggg
cccacctactgcctgccccccaccttccccacagcttccgtgcctcatgagcctggtggc
cccgccccccgcgttgccatctttcgagaagaaggcagtaacggagaccgggagatggcc
gatgccttccacttggctgggtttgaggtgtgggacgtgaccatgcaggacctctgctct
ggagcagtcaggctggacacgttccaaggcatggccttcgtgggcggcttcagctacgcg
gacgtcctgggctctgccaaagggtgggcagccgctgtgacctttaacccccaggccggg
gctgagctgaggcggttccggcaacggccagacaccttcagcctgggcgtgtgtaacggc
tgccagctgctggccctgctgggctgggtgggaggcagtcctggtgacgaggcggcagag
atgggccacgagtcctggccggcccggcctggcctcctgctgcgccacaaccagtctggg
cgtttcgagtcgcgctgggccagcgtgcgagtggggcccgggccggccctgatgctgcga
gggatggagggtgccgtgctgcccgtgtggagcgcccatggggaaggttacatggcattt
tcttccccggaactccaagcccagattgaggccaggggcttggctccgctgcactgggca
gacgatgacggcaaccccacggaacagtaccccctgaatcccaacgggtccccagggggc
atggctggcatctgctcccccgatggccgccacctggctctcatgcctcaccctgagcgg
tctgtgaggccttggcagtgggcgtggcgaccccctccgtttgacactatgaccacctcc
ccctggctccagctcttcatcaatgcccgaaactggacccgggaaggaggctgctga
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